Alab019192.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis laboriosa
Gene Symbol
bab2
Assembly
GCA_014066325.1
Location
JACEOM010001026.1:1455309-1469967[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.8e-27 5.9e-24 85.4 0.4 1 100 35 131 35 135 0.94

Sequence Information

Coding Sequence
atGGAGACGGATCGTTATTGGGGCGTGCACTACAGCGGCGGCATGGCCGGGCAGCACTACTGCCTGCGCTGGAATAACTACCAATCAAACATGACGTCCGTTTTCCATCAACTACTTCAAACGGAAGCTTTTGTCGACGTTACCCTGGCATGTAACGAAGCTTCCTTAAAAGCGCACAAAGTGGTATTATCGGCGTGCAGTTCCTACTTTCAAAAGCTCCTACTTTCAAATCCCTGCAAACATCCGACAATCATTATGCCACAAGATGTATGCTTCAATGatctcaaatttattatagaattcgtCTACAGAGGAGAGATCGATGTTTCGCAAGCAGAACTTCAGTCACTGTTGAAAACAGCCGATCAACTAAAGATCAAAGGATTGTGCGAGGTGCCTGAAAGCAGAGACGGCCCACCCTCGGTAAGTTTGAGCTCACCGCCGAGAGAGCCTGGTACACCTAGGATAAATTTCACCAAGCTGAAGAGGCATCATCCGAGATACAAGAGGCCCAGAACGACGTTCGAGCCTCGTGCCACGGATTCCAGACATTACGATCGATACAAAGAGGaggaatcgaacgaaaattacAATTGGGAGCATAAAGAGACCCACATAGACTGGCAACCCGAAGATGAAGAGTGCACGGAGGCAACAGCGGGAGCAGTAGTCTTGGAAACTTGCCAACGCAACAGTAACAATAGTACCATTACCACCGGCAACACCAGCACCACtagcaataataacaataataataataataataataataacaacaacggCGCTAACGACAACGGCAACGGTAACAGTGCGAGCAATAACAACAACGgtgACATGTTTTGTCATACAGGCCTCGGACATTATGGCCATCATCCGGATCCCGGAGAGGTTGACCTACCACCTGAAACACAACCAACACCACCAAGTGCCACGTTGGTCGGCACTACGATTACCCATTTAAGAGACCCAGATCATCATTCCACAGACATTCAAAATTGTGACAgtgtaaaaatcaaattcgaaACGTTGCATACGATGGATTCGTCGGAcacgatcgatatcgatagcCACATGTCGGATCGGGCGAGCGTTAGTTCAAAGAACGCGGCTGATAGTGATAATATGATGATGATCACACCAGAGTTACTTGGATTAATGCCCTCTGGAAGTTCTGTTCATTCGGATTCAGgcgaaaataattcaagaggGCATTCTGGACAATCCAGCTCTCATCACCATGGCTCAAAATCATGGACTCAAGAGGATATGGATGCTGCTCTGGAAGCATTGAGAAATCATGATATGAGTCTTACGAAAGCTTCTGCAACGTTCGGTATACCCTCGACGACCTTGTGGCAAAGAGCGCATCGGCTTGGCATCGATACTCCAAAAAAGGATGGACCTACTAAATCATGGAGCGATGAGAGTTTAAACAATGCGCTTGATGCATTACGAACGGGCACAATATCGGCGAACAAAGCTTCAAAAGCGTTTGGCATACCATCGAGCACCTTGTACAAAATCGCGAGAAGAGAAGGCATCAGATTGGCTGCACCTTTCAACGCCAGTCCTACTACTTGGTCACCAGCTGATCTCGATCGCGCCCTCGAAGCGATACGTTCCGGTCAAACGTCTGTGCAAAGAGCGTCCACGGAATTTGGAATACCAACAGGAACGTTGTATGGTCGATGCAAAAGAGAAGGAATAGAACTTAGTAGGAGCAATCCTACACCATGGAGCGAAGATGCTATGACCGAAGCTCTCGAAGCTGTTaggttaggtcATATGAGCATTAATCAAGCAGCAATTCATTATAACCTACCGTACTCTTCTTTATACGGTCGTTTTAAGAGAGGAAAATACGAAGAACCAACAGTTGGTGAGATATCTCAAGACGGTAGCAGTCCCCATTTCCATCAAAGTCCAAGTCAAAATCATTCATCTGCCGTACCGGATCAAATGCCGTATCAAGGCAGCTGA
Protein Sequence
METDRYWGVHYSGGMAGQHYCLRWNNYQSNMTSVFHQLLQTEAFVDVTLACNEASLKAHKVVLSACSSYFQKLLLSNPCKHPTIIMPQDVCFNDLKFIIEFVYRGEIDVSQAELQSLLKTADQLKIKGLCEVPESRDGPPSVSLSSPPREPGTPRINFTKLKRHHPRYKRPRTTFEPRATDSRHYDRYKEEESNENYNWEHKETHIDWQPEDEECTEATAGAVVLETCQRNSNNSTITTGNTSTTSNNNNNNNNNNNNNNGANDNGNGNSASNNNNGDMFCHTGLGHYGHHPDPGEVDLPPETQPTPPSATLVGTTITHLRDPDHHSTDIQNCDSVKIKFETLHTMDSSDTIDIDSHMSDRASVSSKNAADSDNMMMITPELLGLMPSGSSVHSDSGENNSRGHSGQSSSHHHGSKSWTQEDMDAALEALRNHDMSLTKASATFGIPSTTLWQRAHRLGIDTPKKDGPTKSWSDESLNNALDALRTGTISANKASKAFGIPSSTLYKIARREGIRLAAPFNASPTTWSPADLDRALEAIRSGQTSVQRASTEFGIPTGTLYGRCKREGIELSRSNPTPWSEDAMTEALEAVRLGHMSINQAAIHYNLPYSSLYGRFKRGKYEEPTVGEISQDGSSPHFHQSPSQNHSSAVPDQMPYQGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00141747; iTF_00228577; iTF_00215623; iTF_00223787; iTF_00223100; iTF_01003650; iTF_01005964; iTF_01003442; iTF_01004990; iTF_00452033; iTF_00451846; iTF_01560354; iTF_01000457; iTF_01000689; iTF_00996946; iTF_01001170; iTF_01560563; iTF_01001494; iTF_00996250; iTF_00317383; iTF_00316904; iTF_00316687; iTF_00317556; iTF_00728745; iTF_00728579; iTF_00048074; iTF_00047880; iTF_00351242; iTF_00350917; iTF_01273194; iTF_01273697; iTF_01273010; iTF_00168300; iTF_00438195; iTF_00437995; iTF_01002196; iTF_01001992; iTF_00046871; iTF_00047244; iTF_01004152; iTF_01207263; iTF_01207477; iTF_00046048; iTF_00046318; iTF_01406660; iTF_01406405; iTF_00385667; iTF_00385187; iTF_01228294; iTF_01099336; iTF_01099106; iTF_00898666; iTF_00898883; iTF_01355221; iTF_01355532; iTF_00730167; iTF_00729971; iTF_00730877; iTF_00730648; iTF_00397190; iTF_00397432; iTF_00397978; iTF_00050719; iTF_00398208; iTF_00059366; iTF_01364550; iTF_00059559; iTF_00058601; iTF_00721166; iTF_00057841; iTF_00905334; iTF_01508775; iTF_01055885; iTF_00828897; iTF_01103458; iTF_01299074; iTF_00266371; iTF_00829635; iTF_01056709; iTF_01129253; iTF_00263623; iTF_00262570; iTF_00798699; iTF_01057772; iTF_01056174; iTF_01057552; iTF_01101235; iTF_00439381; iTF_00629013; iTF_00828693; iTF_00265590; iTF_01057014; iTF_00798489; iTF_00829401; iTF_00263354; iTF_00439610; iTF_00841204; iTF_00840968; iTF_01538087; iTF_01537761; iTF_00760904; iTF_00761065; iTF_00142546; iTF_00142394; iTF_00085505; iTF_00087845; iTF_00087015; iTF_00088139; iTF_00085198; iTF_00084658; iTF_00084443; iTF_00087291; iTF_00183202; iTF_00360994; iTF_00360823; iTF_00360127; iTF_00128099; iTF_00225827; iTF_01405603; iTF_00391429; iTF_00391208; iTF_00633545; iTF_01070949; iTF_01235110; iTF_01232329; iTF_01234262; iTF_01233562; iTF_01232478; iTF_01234942; iTF_01453991; iTF_01512103; iTF_00129641; iTF_00126614; iTF_00860297; iTF_00864553; iTF_01066857; iTF_01069569; iTF_01070274; iTF_01068199; iTF_01067529; iTF_01066158; iTF_01067702; iTF_01067032; iTF_01068888; iTF_01077577; iTF_01077384; iTF_00684714; iTF_00684865; iTF_00961739; iTF_00983531; iTF_01407147; iTF_00862476; iTF_00215117; iTF_00222436; iTF_00214938; iTF_00216987; iTF_00216302; iTF_00216489; iTF_00232528; iTF_00763150; iTF_00865230; iTF_01245134; iTF_00765456; iTF_01408080; iTF_01512912; iTF_01512752; iTF_00183858; iTF_00863187; iTF_01087317; iTF_01087121; iTF_01089909; iTF_01090081; iTF_00088694; iTF_00086080; iTF_00625590; iTF_00625413; iTF_00861046; iTF_00221177; iTF_01424281; iTF_00684250; iTF_00684082; iTF_01169082; iTF_00963932; iTF_00963772; iTF_00452669; iTF_00452498; iTF_00866621; iTF_01539517; iTF_00773918; iTF_00773710; iTF_01255454; iTF_01255796; iTF_01513566; iTF_01513388; iTF_00861791; iTF_00963103; iTF_00964383; iTF_00675936; iTF_00865920; iTF_01413480; iTF_01413017; iTF_00938586; iTF_00174083; iTF_00175847; iTF_00175178; iTF_00175674; iTF_00174428; iTF_00174942; iTF_01411399; iTF_01411652; iTF_01412460; iTF_01412228; iTF_00718735; iTF_00719312; iTF_00718453; iTF_00719549; iTF_00159224; iTF_00159016; iTF_01303224; iTF_01303572; iTF_01414078; iTF_01414333; iTF_01048329; iTF_01048820; iTF_01048150; iTF_01476843; iTF_00015297; iTF_01261761; iTF_00016771; iTF_00014824; iTF_00181227; iTF_01477486; iTF_00014640; iTF_00015472; iTF_00182065; iTF_01477717; iTF_00015960; iTF_00181433; iTF_01477017; iTF_01261916; iTF_00016125; iTF_00016605; iTF_01476094; iTF_01476350; iTF_00181888; iTF_00417476; iTF_00417698; iTF_01523485; iTF_01523277; iTF_00060460; iTF_00060101; iTF_00938124; iTF_00937931; iTF_00460397; iTF_01122349; iTF_01122540; iTF_00939441; iTF_00939728; iTF_00873714; iTF_00982882; iTF_01417618; iTF_00733881; iTF_00982204; iTF_01379123; iTF_01379400; iTF_00459660; iTF_00459897; iTF_00140500; iTF_00962420; iTF_01493492; iTF_01492789; iTF_01493685; iTF_01120310; iTF_01120131; iTF_00117914; iTF_01254707; iTF_00253691; iTF_00253476; iTF_00264187; iTF_00265120; iTF_00264918; iTF_01270620; iTF_01270412; iTF_00756766; iTF_00756541; iTF_01200318; iTF_01200057; iTF_00305567; iTF_00305722;
90% Identity
iTF_00230773;
80% Identity
iTF_00141747;