Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: -
Assembly: GCA_035044305.1
Location: JAWNMF010000133.1:1316594-1323430[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.5e-05 0.0018 18.7 2.1 1 23 252 274 252 274 0.97

2 18 3.6e-05 0.0027 18.2 0.3 1 23 280 302 280 302 0.97

3 18 0.0012 0.089 13.4 0.9 1 23 308 330 308 330 0.95

4 18 1.7e-05 0.0013 19.2 3.1 1 23 336 358 336 358 0.97

5 18 3.9e-05 0.0029 18.1 4.7 1 23 364 386 364 386 0.99

6 18 7.1e-05 0.0053 17.3 5.7 1 23 392 414 392 414 0.97

7 18 3.5e-07 2.6e-05 24.6 4.3 1 23 420 442 420 442 0.98

8 18 1.3e-07 9.4e-06 26.0 2.4 1 23 448 470 448 470 0.97

9 18 7.3e-05 0.0055 17.3 6.7 1 23 477 499 477 499 0.97

10 18 0.00013 0.0095 16.5 6.5 1 23 505 527 505 527 0.98

11 18 1.1e-05 0.00085 19.8 4.5 1 23 533 555 533 555 0.98

12 18 8.2e-06 0.00062 20.2 8.1 1 23 561 583 561 583 0.98

13 18 6.7e-06 0.0005 20.5 7.6 1 23 589 611 589 611 0.97

14 18 7.5e-07 5.6e-05 23.5 7.7 1 23 617 639 617 639 0.98

15 18 0.00023 0.018 15.7 9.5 1 23 645 668 645 668 0.95

16 18 8.3e-05 0.0062 17.1 0.9 1 23 674 696 674 696 0.98

17 18 0.00091 0.068 13.8 3.4 1 23 706 728 706 728 0.97

18 18 1e-05 0.00077 19.9 1.6 1 23 734 757 734 757 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.5e-05	0.0018	18.7	2.1	1	23	252	274	252	274	0.97
2	18	3.6e-05	0.0027	18.2	0.3	1	23	280	302	280	302	0.97
3	18	0.0012	0.089	13.4	0.9	1	23	308	330	308	330	0.95
4	18	1.7e-05	0.0013	19.2	3.1	1	23	336	358	336	358	0.97
5	18	3.9e-05	0.0029	18.1	4.7	1	23	364	386	364	386	0.99
6	18	7.1e-05	0.0053	17.3	5.7	1	23	392	414	392	414	0.97
7	18	3.5e-07	2.6e-05	24.6	4.3	1	23	420	442	420	442	0.98
8	18	1.3e-07	9.4e-06	26.0	2.4	1	23	448	470	448	470	0.97
9	18	7.3e-05	0.0055	17.3	6.7	1	23	477	499	477	499	0.97
10	18	0.00013	0.0095	16.5	6.5	1	23	505	527	505	527	0.98
11	18	1.1e-05	0.00085	19.8	4.5	1	23	533	555	533	555	0.98
12	18	8.2e-06	0.00062	20.2	8.1	1	23	561	583	561	583	0.98
13	18	6.7e-06	0.0005	20.5	7.6	1	23	589	611	589	611	0.97
14	18	7.5e-07	5.6e-05	23.5	7.7	1	23	617	639	617	639	0.98
15	18	0.00023	0.018	15.7	9.5	1	23	645	668	645	668	0.95
16	18	8.3e-05	0.0062	17.1	0.9	1	23	674	696	674	696	0.98
17	18	0.00091	0.068	13.8	3.4	1	23	706	728	706	728	0.97
18	18	1e-05	0.00077	19.9	1.6	1	23	734	757	734	757	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGTCATTGTCCGGTGTCAAATCGGCGGAATCATCGCATAAAGAGGACGGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGGTTCATGGCAGCCAATTGCCACCGCCGCAACTGCCACCGCCGCCTCCCTTACCGCCACAGACGACGCATTCGGCAagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCAGCGGTTGCTGCTGTAATGGCCTCGgccaatgcagcagcagcggctgcagcagccgcatcagcagcggcatcagcacaacagcaacaacagcaacaacaacagcaacaacagcaacaacaacagcaacaacagcagcaacaacagcaacaacagccagcgACAAGCACAAATGCTGGAAGTCAGCAGGGCAGCGCCACGGTGACAACGACCAGCTCGGGCAGCAACGGGGGTGGGAACGGGGGCAACAACTCAACGACAACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCATAGCGAGCGCAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTATACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGCGGTCCCATGTTCACGTGCATTGTATGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgtCAAACACCGCATCAATGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCATACGGGCGATTCGCCGCATCGCTGCTCCTACTGCAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAATCATGTGCGCCTGCACACGGGGGACTCGCCGCACAAGTGCGAATACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGTTGCAACGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACTTGCGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAAGAGTGCGAGCGTCCATTCGCTTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGGTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGTAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcggcgacgacgacgatgcaCACCATACAGCAGATAACAGCAGGCGCCGCAGCGGCGGGTGCCGGGGCCGTCCAGTTAGCACCGGGCCTGGTGCCGCTGGTCACCAGCTCGCTCATCTCGCACAATGCGCAGCAGtcgcagaagcagcagcaggcggcggcagcagttgCCGCCCAACAgcaggcggcagcagcagccgctgcacaGCAACAGGCGGCCGCTGCGGCGGCAGCCCAGCAgcaggcggcggcggcagcagcgcaccagcagcatcagcaacaggtggccgcacaacagcagcaacaacagcagcagcagcaggctgcCGTCGCTgctcatcagcagcagcaacagcagctgcaacagcaacagttgctccAATTGTCCATACAGCAGGCGGCCcaccatcatcagcagcatcagcagcagcagcaacagcagcagcagcagcagcatcatcaacagcagcaacagtcgcatcCGCAGGCaccgccacagcagcaacagcagcagcagcaacagcagccgccgccaCAGGTGCCGATCGCATTGATAAGTGATCCGAGTGCGCTGGCACGTGCCGCCATGCAGTTGCAGCATCTGCCCACAAATGTGGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPSLSGVKSAESSHKEDGGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAASAQQQQQQQQQQQQQQQQQQQQQQQQQQPATSTNAGSQQGSATVTTTSSGSNGGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGYTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLAPGLVPLVTSSLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQQHHQQQQQSHPQAPPQQQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499009; iTF_00577185; iTF_01325793; iTF_00500450; iTF_00562594; iTF_00568386; iTF_00471012; iTF_00589668; iTF_00472481; iTF_00616322; iTF_00523087; iTF_00520761; iTF_00596069; iTF_00608581; iTF_00535462; iTF_00591110; iTF_00506248; iTF_00901637; iTF_00563304; iTF_00577928; iTF_01321320; iTF_00251497; iTF_00498281; iTF_00522345; iTF_00601961; iTF_00507017; iTF_00537642; iTF_00586095; iTF_01320598; iTF_00569113; iTF_00610793; iTF_00802985; iTF_00546785; iTF_00502658; iTF_00559623; iTF_00599719; iTF_00473196; iTF_00554508; iTF_00573453; iTF_00598285; iTF_00516401; iTF_00520049; iTF_00544625; iTF_00545377; iTF_00540501; iTF_00479608; iTF_00551720; iTF_00493791; iTF_00512864; iTF_00532512; iTF_00558058; iTF_00062155; iTF_00061319; iTF_00525291; iTF_00531083; iTF_01364076; iTF_00555981; iTF_00509230; iTF_00614316; iTF_00571310; iTF_00618564; iTF_00503405; iTF_00523839; iTF_00561887; iTF_00612224; iTF_00613613; iTF_00604241; iTF_00555236; iTF_00490200; iTF_00595374; iTF_00607214; iTF_00519312; iTF_00582384; iTF_00805328; iTF_00803740; iTF_00339314; iTF_00336120; iTF_00890290; iTF_00891153; iTF_00917362; iTF_01328019; iTF_00526708; iTF_01326580; iTF_00495989; iTF_00567663; iTF_00832309; iTF_00476758; iTF_00806102; iTF_00534711; iTF_01322071; iTF_00501208; iTF_00509944; iTF_00538360; iTF_00533977; iTF_00572729; iTF_00918329; iTF_00511418; iTF_00543879; iTF_00575738; iTF_00914650; iTF_01556250; iTF_01319899; iTF_00493084; iTF_00583836; iTF_01570364; iTF_00490909; iTF_00548957; iTF_00584541; iTF_00552446; iTF_00528191; iTF_00485986; iTF_00497542; iTF_00518568; iTF_00542570; iTF_00501932; iTF_00557326; iTF_00482384; iTF_00564784; iTF_00583091; iTF_00574197; iTF_00513590; iTF_00576473; iTF_00495258; iTF_00570522; iTF_00610042; iTF_00619994; iTF_00496764; iTF_00566940; iTF_00597533; iTF_00499710; iTF_00593246; iTF_00521535; iTF_00558879; iTF_00517120; iTF_00528959; iTF_01549695; iTF_00508480; iTF_01327296;
90% Identity: iTF_00499009; iTF_00543879; iTF_00511418; iTF_00552446; iTF_00577185; iTF_01325793; iTF_00485986; iTF_00500450; iTF_00616322; iTF_00901637; iTF_00535462; iTF_00518568; iTF_01321320; iTF_00498281; iTF_00507017; iTF_00522345; iTF_00537642; iTF_00542570; iTF_00525291; iTF_00501932; iTF_00598285; iTF_00557326; iTF_00607214; iTF_00523087; iTF_00567663; iTF_00495989; iTF_00476758; iTF_00538360; iTF_00586095; iTF_00482384; iTF_00519312; iTF_00564784; iTF_00805328; iTF_00583091; iTF_01328019; iTF_01326580; iTF_01320598; iTF_01322071; iTF_00832309; iTF_00806102; iTF_00509944; iTF_00576473; iTF_00495258; iTF_00619994; iTF_00593246; iTF_00570522; iTF_00513590; iTF_00575738; iTF_00610042; iTF_01556250; iTF_00496764; iTF_00566940; iTF_00497542; iTF_00803740; iTF_01570364; iTF_00490909; iTF_00548957; iTF_00597533; iTF_00499710; iTF_00521535; iTF_00528191; iTF_00528959; iTF_00558879; iTF_00574197; iTF_01549695; iTF_00558058; iTF_00531083; iTF_00508480; iTF_00517120; iTF_01327296;
80% Identity: -