Dsuc017346.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sucinea
Gene Symbol
-
Assembly
GCA_018150745.1
Location
JAECWP010000123.1:459482-466046[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0013 19.1 2.1 1 23 223 245 223 245 0.97
2 18 5.7e-06 0.00042 20.6 0.4 1 23 251 273 251 273 0.97
3 18 0.00084 0.062 13.8 0.9 1 23 279 301 279 301 0.95
4 18 1.2e-05 0.00089 19.6 3.1 1 23 307 329 307 329 0.97
5 18 2.7e-05 0.002 18.5 4.7 1 23 335 357 335 357 0.99
6 18 5e-05 0.0037 17.6 5.7 1 23 363 385 363 385 0.97
7 18 2.5e-07 1.8e-05 24.9 4.3 1 23 391 413 391 413 0.98
8 18 8.8e-08 6.5e-06 26.3 2.4 1 23 419 441 419 441 0.97
9 18 5.1e-05 0.0038 17.6 6.7 1 23 448 470 448 470 0.97
10 18 8.9e-05 0.0066 16.9 6.5 1 23 476 498 476 498 0.98
11 18 8e-06 0.00059 20.2 4.5 1 23 504 526 504 526 0.98
12 18 5.8e-06 0.00043 20.6 8.1 1 23 532 554 532 554 0.98
13 18 4.7e-06 0.00035 20.9 7.6 1 23 560 582 560 582 0.97
14 18 5.3e-07 3.9e-05 23.9 7.7 1 23 588 610 588 610 0.98
15 18 0.00016 0.012 16.0 9.5 1 23 616 639 616 639 0.95
16 18 5.8e-05 0.0043 17.4 0.9 1 23 645 667 645 667 0.98
17 18 0.00062 0.046 14.2 4.4 1 23 677 699 677 699 0.98
18 18 7.3e-06 0.00054 20.3 1.6 1 23 705 728 705 728 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTTAGCGCTGCCAGTTCGGTTCCATCGGTGGTTGCACCGGTGGTAACCACTGGAGGCACAACAATTACCTTGGGCGGTGGTCCACCACCACCGTCGTCATCATTGGCCAAATCGGAGATTAAGGAAGATGGAAAACCACCGCATGGCATGGAATTGTATAAAGTGAACATTGAGGATATTTCGCAATTGTTTACATATCATGAAGTCTTTGGCAAAATACATGGAGATGTGGTCAATCATCAATTGGTGGCAGCGGCACACGGCGGGCAATTGCCACCGCCACCGCCTTTGCCGCCGCAGACACATGCATCCAGTGCAGCGGCAGCTGCAGCGGCGGCAGCAGCAAGTACGAATAATGCGGCGGTGGCTGCTGTAATGGCCTCGGCCAATGCAGCAGCGGCGGCTGCAGCTGCCGCTTCGGCCGCGGGAGTGCCCTCCACCACGAGTGGAATACCCGGAGTAGTAACGACAACCACAAGCTCATCCACCGGGAGCAGTGTAGCTAGTGGGGGCGGCGGGGGTACCACATCGAGCACAACGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCCTACATGGCAACGTGGACGCTGGTGGCGGCGGTCAGACCCAGGTGGCCCTAGCGCCTGATGGCACGCCCATTGCCACGGGGACGCATGTCTGCGATATATGTGGCAAGATGTTCCAGTTTCGCTATCAGCTTATAGTCCATCGTCGCTATCATAGCGAACGCAAACCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTCACCACATCGCAGGATCTGACCCGACATGGTAAAATCCATATTGGCGGACCGATGTTTACCTGCATCGTTTGCTTCAATGTCTTCGCAAATAACACCAGCCTGGAGCGGCATATGAAGCGTCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCCCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGTGAAACGCCCTTCCGTTGCCAGTACTGCGCAAAGACGTTTACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGTGATGTCTGTGGCAAGAAATATACGCGCAAGGAGCATCTAGCTAATCATATGCGCTCCCACACAAACGAGACACCGTTCCGCTGTGAAATCTGTGGCAAGAGCTTCAGCCGCAAGGAACACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCACATCGGTGCGATTTCTGCTCCAAGACGTTTACGCGCAAGGAACATCTGTTAAACCACGTGCGTCAGCACACGGGTGAATCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAATCACATTCGTCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACAAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACTTACTGCACAAAGACGTTCACACGCAAGGAGCACCTGACGAATCATGTGCGCCAGCATACGGGCGACTCGCCCCATCGCTGCTCCTACTGCAAGAAGACATTCACACGCAAGGAGCATTTGACGAATCATGTGCGATTGCATACGGGGGACTCACCGCACAAGTGTGAATATTGCCAGAAGACATTCACACGGAAGGAGCATCTCAATAATCACATGCGTCAGCACTCCAGCGATAATCCGCACTGTTGCAATGTCTGCAATAAGCCATTTACCCGCAAGGAGCATCTGATTAATCATATGTCGCGCTGCCATACGGGCGATCGTCCCTTCACATGTGAGACATGCGGCAAATCGTTTCCACTCAAGGGCAATCTGTTGTTCCATCAGCGTAGCCATACCAAGGGTCAGGATATGGAGCGTCCGTTCTCATGCGAAAAGTGTCCTAAGAACTTTATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCAGCAGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCATTCGGCGACAACGATGCACACCATACAACAGATAACGGGGGGAGCAGCAGGAGCCGCCATGCAATTGCAACATTTGCCGGCCAATGTGGAACAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGGPPPPSSSLAKSEIKEDGKPPHGMELYKVNIEDISQLFTYHEVFGKIHGDVVNHQLVAAAHGGQLPPPPPLPPQTHASSAAAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGVPSTTSGIPGVVTTTTSSSTGSSVASGGGGGTTSSTTGELLMPKMEGGLHGNVDAGGGGQTQVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQDMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTMHTIQQITGGAAGAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00555236; iTF_00555981; iTF_00591110; iTF_00577928; iTF_00523839; iTF_00571310; iTF_00612224;
80% Identity
iTF_00555236;