Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000617.1:11197781-11204627[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.5e-05 0.0015 18.8 2.1 1 23 243 265 243 265 0.97

2 18 8.1e-06 0.0005 20.3 0.4 1 23 271 293 271 293 0.97

3 18 0.0012 0.074 13.5 0.9 1 23 299 321 299 321 0.95

4 18 1.7e-05 0.0011 19.3 3.1 1 23 327 349 327 349 0.97

5 18 3.9e-05 0.0024 18.1 4.7 1 23 355 377 355 377 0.99

6 18 7.1e-05 0.0044 17.3 5.7 1 23 383 405 383 405 0.97

7 18 3.5e-07 2.2e-05 24.6 4.3 1 23 411 433 411 433 0.98

8 18 1.2e-07 7.7e-06 26.0 2.4 1 23 439 461 439 461 0.97

9 18 7.3e-05 0.0045 17.3 6.7 1 23 468 490 468 490 0.97

10 18 0.00013 0.0078 16.5 6.5 1 23 496 518 496 518 0.98

11 18 1.1e-05 0.0007 19.8 4.5 1 23 524 546 524 546 0.98

12 18 8.2e-06 0.00051 20.3 8.1 1 23 552 574 552 574 0.98

13 18 6.7e-06 0.00041 20.5 7.6 1 23 580 602 580 602 0.97

14 18 7.5e-07 4.6e-05 23.5 7.7 1 23 608 630 608 630 0.98

15 18 0.00023 0.014 15.7 9.5 1 23 636 659 636 659 0.95

16 18 8.3e-05 0.0051 17.1 0.9 1 23 665 687 665 687 0.98

17 18 0.0009 0.056 13.8 3.4 1 23 697 719 697 719 0.97

18 18 1e-05 0.00064 19.9 1.6 1 23 725 748 725 748 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.5e-05	0.0015	18.8	2.1	1	23	243	265	243	265	0.97
2	18	8.1e-06	0.0005	20.3	0.4	1	23	271	293	271	293	0.97
3	18	0.0012	0.074	13.5	0.9	1	23	299	321	299	321	0.95
4	18	1.7e-05	0.0011	19.3	3.1	1	23	327	349	327	349	0.97
5	18	3.9e-05	0.0024	18.1	4.7	1	23	355	377	355	377	0.99
6	18	7.1e-05	0.0044	17.3	5.7	1	23	383	405	383	405	0.97
7	18	3.5e-07	2.2e-05	24.6	4.3	1	23	411	433	411	433	0.98
8	18	1.2e-07	7.7e-06	26.0	2.4	1	23	439	461	439	461	0.97
9	18	7.3e-05	0.0045	17.3	6.7	1	23	468	490	468	490	0.97
10	18	0.00013	0.0078	16.5	6.5	1	23	496	518	496	518	0.98
11	18	1.1e-05	0.0007	19.8	4.5	1	23	524	546	524	546	0.98
12	18	8.2e-06	0.00051	20.3	8.1	1	23	552	574	552	574	0.98
13	18	6.7e-06	0.00041	20.5	7.6	1	23	580	602	580	602	0.97
14	18	7.5e-07	4.6e-05	23.5	7.7	1	23	608	630	608	630	0.98
15	18	0.00023	0.014	15.7	9.5	1	23	636	659	636	659	0.95
16	18	8.3e-05	0.0051	17.1	0.9	1	23	665	687	665	687	0.98
17	18	0.0009	0.056	13.8	3.4	1	23	697	719	697	719	0.97
18	18	1e-05	0.00064	19.9	1.6	1	23	725	748	725	748	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCACTACCCAGTAACAAGTCGGAACATAAAGAGGACGGCGGCAAGCCGCCGCAcggcattgaaatgtataaaGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTTGTTAATCATGTTGCGGCGGTACATGGCAGCcaactgccgccgccgcaatTGCCACCGCCTCCGCCACTACCGCCACAGACGACGCATTCGGCtagcgcagctgcagcagcagcggcggtgTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCGgccaatgcagcagcagcggctgcagcggccGCTTCAGCAGCGGTCACggcccaacagcaacagcagcaacaacagcaacagcagcaacaacaacagcagcaacagcaacaacaagccccGGCGACAAGCACGAATGCCGGAACCCAACAGGGCAGCGCCACAGTGACAACCACTAGCTCCGGCAGCAACGGGGGGAATGGGGGCAATAACTCGACAACGACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTTTGCGACATTTGTGGCAAAATGTTCCAGTTTCGTTATCAGCTAATTGTGCATCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATTCACATTGGAGGTCCAATGTTCACCTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACAAGCTTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTTAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACAAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACAAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCACCGTTGCAGCTATTGCAAGAAGACGTTCACCCGCAAGGAGCACCTGACGAACCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCATTCGAGCGACAATCCGCATTGTTGCAATGTGTGCAACAAGCCGTTTACGCGCAAAGAGCATCTGATTAATCACATGTCCCGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAGTCCTTCCCCCTCAAAGGCAACCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAATGCGAGCGTCCCTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAACCACCCGGATGCTATGATGCCACCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACCACGATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCCGGCGCCGGTGCCGTACAGTTGACGCCCGGCCTGGTGCCGCTCGTCACCAGCACGCTCATCTCGCACAACGCCCAGCAGtcgcagaaacagcagcaggtgGCGGCAGCGGTGGCCGCCCAACAgcaggcggcggcagcggccgcgGCACAGCAACAGgcggccgcagcggcagccgcccaacagcaggcggcggcggcggcagcgcatcaacagcatcagcaacaggtggccgcacagcagcagcaacagcagcagcagcaagcggcAGTTGCTgcacaccagcagcagcaacagcaactgcagcagcaacagttgctgcaatTGTCCATACAGCAGGCggcgcatcatcatcagcaccagcagcagcaacaacagcagcaacagcagcagcaacagcatcatcaacagcagcaacaacagtcgcATCCGCAGGCGccgccacaacagcagcagcaacaacaacaacagccgccacCGCAGGTGCCAATTGCATTGATAAGTGATCCGAGCGCGCTGGCGCGTGCCGccatgcagctgcagcatctgCCCACAAATGTTGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPSNKSEHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAVTAQQQQQQQQQQQQQQQQQQQQQAPATSTNAGTQQGSATVTTTSSGSNGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQVAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQHQQQQQQQQQQQQQHHQQQQQQSHPQAPPQQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -