Basic Information

Insect: Drosophila heteroneura
Gene Symbol: -
Assembly: GCA_035042245.1
Location: JAWNLO010000967.1:542851-549839[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.4e-05 0.0015 18.7 2.1 1 23 253 275 253 275 0.97

2 18 7.9e-06 0.0005 20.3 0.4 1 23 281 303 281 303 0.97

3 18 0.0012 0.074 13.4 0.9 1 23 309 331 309 331 0.95

4 18 1.7e-05 0.0011 19.2 3.1 1 23 337 359 337 359 0.97

5 18 3.8e-05 0.0024 18.1 4.7 1 23 365 387 365 387 0.99

6 18 6.9e-05 0.0044 17.3 5.7 1 23 393 415 393 415 0.97

7 18 3.4e-07 2.2e-05 24.6 4.3 1 23 421 443 421 443 0.98

8 18 1.2e-07 7.7e-06 26.0 2.4 1 23 449 471 449 471 0.97

9 18 7.1e-05 0.0045 17.3 6.7 1 23 478 500 478 500 0.97

10 18 0.00012 0.0078 16.5 6.5 1 23 506 528 506 528 0.98

11 18 1.1e-05 0.0007 19.8 4.5 1 23 534 556 534 556 0.98

12 18 8e-06 0.00051 20.2 8.1 1 23 562 584 562 584 0.98

13 18 6.5e-06 0.00041 20.5 7.6 1 23 590 612 590 612 0.97

14 18 7.3e-07 4.6e-05 23.5 7.7 1 23 618 640 618 640 0.98

15 18 0.00023 0.014 15.7 9.5 1 23 646 669 646 669 0.95

16 18 8.1e-05 0.0051 17.1 0.9 1 23 675 697 675 697 0.98

17 18 0.00088 0.056 13.8 3.4 1 23 707 729 707 729 0.97

18 18 1e-05 0.00064 19.9 1.6 1 23 735 758 735 758 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.4e-05	0.0015	18.7	2.1	1	23	253	275	253	275	0.97
2	18	7.9e-06	0.0005	20.3	0.4	1	23	281	303	281	303	0.97
3	18	0.0012	0.074	13.4	0.9	1	23	309	331	309	331	0.95
4	18	1.7e-05	0.0011	19.2	3.1	1	23	337	359	337	359	0.97
5	18	3.8e-05	0.0024	18.1	4.7	1	23	365	387	365	387	0.99
6	18	6.9e-05	0.0044	17.3	5.7	1	23	393	415	393	415	0.97
7	18	3.4e-07	2.2e-05	24.6	4.3	1	23	421	443	421	443	0.98
8	18	1.2e-07	7.7e-06	26.0	2.4	1	23	449	471	449	471	0.97
9	18	7.1e-05	0.0045	17.3	6.7	1	23	478	500	478	500	0.97
10	18	0.00012	0.0078	16.5	6.5	1	23	506	528	506	528	0.98
11	18	1.1e-05	0.0007	19.8	4.5	1	23	534	556	534	556	0.98
12	18	8e-06	0.00051	20.2	8.1	1	23	562	584	562	584	0.98
13	18	6.5e-06	0.00041	20.5	7.6	1	23	590	612	590	612	0.97
14	18	7.3e-07	4.6e-05	23.5	7.7	1	23	618	640	618	640	0.98
15	18	0.00023	0.014	15.7	9.5	1	23	646	669	646	669	0.95
16	18	8.1e-05	0.0051	17.1	0.9	1	23	675	697	675	697	0.98
17	18	0.00088	0.056	13.8	3.4	1	23	707	729	707	729	0.97
18	18	1e-05	0.00064	19.9	1.6	1	23	735	758	735	758	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTAGGCGGACCGCCGTCATTGCCCGGTGTCAAATCGTCGGAATCATCGCATAAAGAGGACGTCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTCACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGGTGCATGGCAGCCAGTTGCCACCGCCGCAACTGCCACCGCCGCCCCCCCTACCGCCACAGACGACGCATTCGGCAagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCAgccgttgctgctgtaatGGCCTCGGCCAATGCAGCAGCcgcggctgcagcagccgcatcagTAGCGGCatcagcacaacagcaacaacagcaacaacaacagcaacaacagcaacaacaacagcaacaacagcagcaacaacagcaacaacaacagccagcgaCAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACAACGACCAGCTCGGGCAGCAACGGGGGTGGGAATGGGGGCAACAACTCAACGACAACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCACAGCGAGCGCAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGTGGTCCCATGTTCACGTGCATTGTCTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCATGTGCGCCAGCACACTGGAGAGTCGCCACATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCATACGGGCGATTCGCCGCATCGCTGCTCCTACTGTAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAATCATGTGCGTCTGCACACGGGGGACTCGCCGCACAAGTGCGAGTACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCTAGCGACAATCCCCATTGTTGCAACGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTGTCGCACATGCGCTCCCATTCGGGAGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcggcgacgacgacgatgcaCACCATCCAGCAGATAACAGCGGGCGCCGCAGCAGCGGGCGCCGGGGCCGTCCAGTTAGCGCCAGGCCTGGTGCCGCTGGTCACCAGCTCCCTCATCTCGCACAATGCGCAGCAGtcacagaagcagcagcaggcggcggcagcagttgccgcccaacagcaggcggcagcagcagccgctgcacaGCAACAGGCGGCCGCTGCGGCGGCAGCCCAGCagcaggcggcggcggcagcagcgcatcagcagcatcagcaacaggtggccgcacaacagcaacaacaacagcagcagcagcaggctgcCGTCGCtgcgcatcagcagcagcaacagcagctgcagcagcaacagttgctccaATTGTCCATACAGCAGGCggcccatcatcatcagcagcatcagcagcagcagcaacaacagcagcagcagcagcagcagcaacatcaccaacagcagcaacagtcgcatcCGCAGGCaccgccacagcagcaacagcagcagcaacaacagccgccgCCACAGGTGCCGATCGCATTGATAAGTGATCCGAGTGCGCTGGCACGTGCCGccatgcagctgcagcatctgCCCACAAATGTGGAACAACATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPSLPGVKSSESSHKEDVGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASVAASAQQQQQQQQQQQQQQQQQQQQQQQQQQQPATSTNAGSQQGSATVTTTSSGSNGGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLAPGLVPLVTSSLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQQQQQHHQQQQQSHPQAPPQQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -