Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000019.1:8920094-8927588[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.5e-05 0.0019 18.8 2.1 1 23 244 266 244 266 0.97

2 18 8.3e-06 0.00061 20.3 0.4 1 23 272 294 272 294 0.97

3 18 0.0012 0.09 13.4 0.9 1 23 300 322 300 322 0.95

4 18 1.7e-05 0.0013 19.2 3.1 1 23 328 350 328 350 0.97

5 18 4e-05 0.0029 18.1 4.7 1 23 356 378 356 378 0.99

6 18 7.3e-05 0.0054 17.3 5.7 1 23 384 406 384 406 0.97

7 18 3.6e-07 2.6e-05 24.6 4.3 1 23 412 434 412 434 0.98

8 18 1.3e-07 9.4e-06 26.0 2.4 1 23 440 462 440 462 0.97

9 18 7.4e-05 0.0055 17.3 6.7 1 23 469 491 469 491 0.97

10 18 0.00013 0.0096 16.5 6.5 1 23 497 519 497 519 0.98

11 18 1.2e-05 0.00085 19.8 4.5 1 23 525 547 525 547 0.98

12 18 8.4e-06 0.00062 20.3 8.1 1 23 553 575 553 575 0.98

13 18 6.8e-06 0.0005 20.5 7.6 1 23 581 603 581 603 0.97

14 18 7.6e-07 5.6e-05 23.5 7.7 1 23 609 631 609 631 0.98

15 18 0.00024 0.018 15.7 9.5 1 23 637 660 637 660 0.95

16 18 8.5e-05 0.0062 17.1 0.9 1 23 666 688 666 688 0.98

17 18 0.00092 0.068 13.8 3.4 1 23 698 720 698 720 0.97

18 18 1.1e-05 0.00078 19.9 1.6 1 23 726 749 726 749 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.5e-05	0.0019	18.8	2.1	1	23	244	266	244	266	0.97
2	18	8.3e-06	0.00061	20.3	0.4	1	23	272	294	272	294	0.97
3	18	0.0012	0.09	13.4	0.9	1	23	300	322	300	322	0.95
4	18	1.7e-05	0.0013	19.2	3.1	1	23	328	350	328	350	0.97
5	18	4e-05	0.0029	18.1	4.7	1	23	356	378	356	378	0.99
6	18	7.3e-05	0.0054	17.3	5.7	1	23	384	406	384	406	0.97
7	18	3.6e-07	2.6e-05	24.6	4.3	1	23	412	434	412	434	0.98
8	18	1.3e-07	9.4e-06	26.0	2.4	1	23	440	462	440	462	0.97
9	18	7.4e-05	0.0055	17.3	6.7	1	23	469	491	469	491	0.97
10	18	0.00013	0.0096	16.5	6.5	1	23	497	519	497	519	0.98
11	18	1.2e-05	0.00085	19.8	4.5	1	23	525	547	525	547	0.98
12	18	8.4e-06	0.00062	20.3	8.1	1	23	553	575	553	575	0.98
13	18	6.8e-06	0.0005	20.5	7.6	1	23	581	603	581	603	0.97
14	18	7.6e-07	5.6e-05	23.5	7.7	1	23	609	631	609	631	0.98
15	18	0.00024	0.018	15.7	9.5	1	23	637	660	637	660	0.95
16	18	8.5e-05	0.0062	17.1	0.9	1	23	666	688	666	688	0.98
17	18	0.00092	0.068	13.8	3.4	1	23	698	720	698	720	0.97
18	18	1.1e-05	0.00078	19.9	1.6	1	23	726	749	726	749	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCAGATCATAAAGAGGACGGCAGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGTAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGCTGCCACCGCCGCAattgccaccgccaccgccattGCCACCGCAGACGACGCATTCGGCtagcgcagctgcagctgcagcggcggtGTCCACAAACAATGCAGCCGTCGCTGCTGTAATGGCATCAGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCCTCGGCCGCAGCCACggcccaacagcaacagcaacaacaacagcagcaacaacagcaacagcaagccCCAGCGACAAGCACAAATGCTGGAAGCACCCAGCAGGGCAGCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAACGGGGCCAATgggggcaacaacaatgccacgacaacaacgacgggTGAGTTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCGTTGATGGGCAATCGAGCGTTGCGTTGGCGCCAGATGGCACGCCCATAGCGACTGGGACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGTCCCATGTTCACTTGCATTGTCTGCTTCAATGTGTTTGCCAACAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTCCGCCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACGTTCACCCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGCTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCACCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAATCGTTCCCCCTCAAGGGCAACCTCTTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAATGCGAGCGTCCATTTGCCTGCGAGAAGTGCCCCAAGAACTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCATTCGGCGACGACCACAATGCACACCATTCAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCTGGTGCCGTCCAGCTGACGCCCGGCCTGGTGCCGCTCGTCACCAGCACGCTCATCTCCCATAATGCCCAGCAGtcgcagaagcagcagcagcaggtggctgctgcagttgctgcccagcagcaggcggcagcagcagccgctgcccaACAGCAGGCAGCCGCAGCGGCTCAGCAGcaagcggcggcggcagcagcacaccagcagcatcagcaacaggtggccgcacagcagcagcaacaacagcagcaggcagcagttgctgcacatcagcagcagcaacagcagctgcagcagcaacagttgctgcaatTGTCCATACAGCAGGCGgcgcatcatcatcagcagcaacagcagcatcaacagcaacaacaacagcagcagcagcaacaacaacaacagcagcagcagcagcagcaacatcatccaCAGCAACAGTCGCATCCTCAGGCgccgccacagcagcagcaacaacagcaacagccaccaCCACAGGTGCCCATTGCATTGATAAGTGATCCCAGCGCGCTGGCTCGTGCCGCCATGCAGTTGCAGCATCTGCCCACAAATGTGGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQQQQQAPATSTNAGSTQQGSATVTTTSSSGSNGGNGANGGNNNATTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQQVAAAVAAQQQAAAAAAAQQQAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQQQHQQQQQQQQQQQQQQQQQQQQHHPQQQSHPQAPPQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00479608;
80% Identity: -