Basic Information

Insect: Drosophila novamexicana
Gene Symbol: -
Assembly: GCA_003285875.3
Location: NW:863803-879527[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.1e-05 0.0011 18.8 2.1 1 23 238 260 238 260 0.97

2 18 7.1e-06 0.00038 20.3 0.4 1 23 266 288 266 288 0.97

3 18 0.001 0.055 13.5 0.9 1 23 294 316 294 316 0.95

4 18 1.5e-05 0.0008 19.3 3.1 1 23 322 344 322 344 0.97

5 18 3.4e-05 0.0018 18.2 4.7 1 23 350 372 350 372 0.99

6 18 6.2e-05 0.0033 17.3 5.7 1 23 378 400 378 400 0.97

7 18 3.1e-07 1.6e-05 24.6 4.3 1 23 406 428 406 428 0.98

8 18 1.1e-07 5.8e-06 26.0 2.4 1 23 434 456 434 456 0.97

9 18 6.4e-05 0.0034 17.3 6.7 1 23 463 485 463 485 0.97

10 18 0.00011 0.0059 16.5 6.5 1 23 491 513 491 513 0.98

11 18 9.9e-06 0.00053 19.8 4.5 1 23 519 541 519 541 0.98

12 18 7.2e-06 0.00038 20.3 8.1 1 23 547 569 547 569 0.98

13 18 5.8e-06 0.00031 20.6 7.6 1 23 575 597 575 597 0.97

14 18 6.5e-07 3.5e-05 23.6 7.7 1 23 603 625 603 625 0.98

15 18 0.0002 0.011 15.7 9.5 1 23 631 654 631 654 0.95

16 18 7.2e-05 0.0039 17.1 0.9 1 23 660 682 660 682 0.98

17 18 0.00079 0.042 13.9 3.4 1 23 692 714 692 714 0.97

18 18 9e-06 0.00048 20.0 1.6 1 23 720 743 720 743 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.1e-05	0.0011	18.8	2.1	1	23	238	260	238	260	0.97
2	18	7.1e-06	0.00038	20.3	0.4	1	23	266	288	266	288	0.97
3	18	0.001	0.055	13.5	0.9	1	23	294	316	294	316	0.95
4	18	1.5e-05	0.0008	19.3	3.1	1	23	322	344	322	344	0.97
5	18	3.4e-05	0.0018	18.2	4.7	1	23	350	372	350	372	0.99
6	18	6.2e-05	0.0033	17.3	5.7	1	23	378	400	378	400	0.97
7	18	3.1e-07	1.6e-05	24.6	4.3	1	23	406	428	406	428	0.98
8	18	1.1e-07	5.8e-06	26.0	2.4	1	23	434	456	434	456	0.97
9	18	6.4e-05	0.0034	17.3	6.7	1	23	463	485	463	485	0.97
10	18	0.00011	0.0059	16.5	6.5	1	23	491	513	491	513	0.98
11	18	9.9e-06	0.00053	19.8	4.5	1	23	519	541	519	541	0.98
12	18	7.2e-06	0.00038	20.3	8.1	1	23	547	569	547	569	0.98
13	18	5.8e-06	0.00031	20.6	7.6	1	23	575	597	575	597	0.97
14	18	6.5e-07	3.5e-05	23.6	7.7	1	23	603	625	603	625	0.98
15	18	0.0002	0.011	15.7	9.5	1	23	631	654	631	654	0.95
16	18	7.2e-05	0.0039	17.1	0.9	1	23	660	682	660	682	0.98
17	18	0.00079	0.042	13.9	3.4	1	23	692	714	692	714	0.97
18	18	9e-06	0.00048	20.0	1.6	1	23	720	743	720	743	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCATTGCCCGGCAGCAAATCAGATCATAAAGAGGACGGCGGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGCTGCCACCGCCGCAgctgccaccgccaccgccactaCCGCCGCAGACAACGCATTCGGCtagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCCGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCCTCAGCGGCGGCCACagcccaacagcaacagcagcaacagcaagccCCAGCGACAAGCACAAATGCTGGATCACAACAGGGCAGCGCCACGGTGACCACGACTAGCTCTGGCAGCAACGGGGGGAATGGGggccagaacaacaacaacaataacaacaactcgacaacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAATCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAAATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGGCATGGGAAGATCCACATTGGCGGTCCCATGTTCACTTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACAAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGTCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTTAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTTCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCATTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATTTGACGAATCATGTACGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCACTCGAGCGACAATCCCCATTGTTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCATTTGATTAATCATATGTCCCGTTGCCACACCGGCGATCGTCCTTTCACCTGCGAGACGTGCGGTAAATCGTTCCCCCTCAAGGGTAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACCACGATGCACACCATTCAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCCGGTGCCGTCCAGTTAACGCCTGGCCTGGTGCCGCTTGTCACCAGCACGCTCATCTCCCACAATGCCCAGCAGtcgcagaagcagcagcaggcggccgCAGCAGTTGCCGCAcaacagcaggcggcagcagcagccgctgcccagcaacaggcggcggcggctcaacaacaagcggcagcagcagcgcatcagcaacatcagcaacaggtggccgcacagcagcaacaacagcaacagcaggcggcagTCGCtgcacatcagcagcagcaacagcaactgcagcagcaacagttgctgcaatTGTCCATACAGCATGCGGCGcatcatcaccagcagcatcagcagcagcagcaacagcagcagcaacatcatcaacagcagcaacaacaacaacaacagtcgcATCCACAGGCGccgccacagcaacaacaacagcaacagccaccgCCACAGGTGCCAATCGCATTGATAAGTGATCCAAGCGCGCTGGCGCGTGCCGCGATGCAACTGCAGCATCTGCCCACAAATGTGGAGCAACATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGSKSDHKEDGGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGQNNNNNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQHAAHHHQQHQQQQQQQQQHHQQQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00479608;
80% Identity: -