Basic Information

Insect: Drosophila conformis
Gene Symbol: -
Assembly: GCA_035041375.1
Location: JAWNLE010000279.1:1985053-1991805[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.6e-05 0.0017 18.8 2.1 1 23 248 270 248 270 0.97

2 18 8.5e-06 0.00055 20.3 0.4 1 23 276 298 276 298 0.97

3 18 0.0012 0.081 13.5 0.9 1 23 304 326 304 326 0.95

4 18 1.8e-05 0.0012 19.3 3.1 1 23 332 354 332 354 0.97

5 18 4.1e-05 0.0026 18.1 4.7 1 23 360 382 360 382 0.99

6 18 7.5e-05 0.0048 17.3 5.7 1 23 388 410 388 410 0.97

7 18 3.7e-07 2.4e-05 24.6 4.3 1 23 416 438 416 438 0.98

8 18 1.3e-07 8.5e-06 26.0 2.4 1 23 444 466 444 466 0.97

9 18 7.6e-05 0.005 17.3 6.7 1 23 473 495 473 495 0.97

10 18 0.00013 0.0086 16.5 6.5 1 23 501 523 501 523 0.98

11 18 1.2e-05 0.00077 19.8 4.5 1 23 529 551 529 551 0.98

12 18 8.6e-06 0.00056 20.3 8.1 1 23 557 579 557 579 0.98

13 18 7e-06 0.00045 20.5 7.6 1 23 585 607 585 607 0.97

14 18 7.8e-07 5.1e-05 23.5 7.7 1 23 613 635 613 635 0.98

15 18 0.00024 0.016 15.7 9.5 1 23 641 664 641 664 0.95

16 18 8.7e-05 0.0056 17.1 0.9 1 23 670 692 670 692 0.98

17 18 0.00095 0.062 13.8 3.4 1 23 702 724 702 724 0.97

18 18 1.1e-05 0.0007 19.9 1.6 1 23 730 753 730 753 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.6e-05	0.0017	18.8	2.1	1	23	248	270	248	270	0.97
2	18	8.5e-06	0.00055	20.3	0.4	1	23	276	298	276	298	0.97
3	18	0.0012	0.081	13.5	0.9	1	23	304	326	304	326	0.95
4	18	1.8e-05	0.0012	19.3	3.1	1	23	332	354	332	354	0.97
5	18	4.1e-05	0.0026	18.1	4.7	1	23	360	382	360	382	0.99
6	18	7.5e-05	0.0048	17.3	5.7	1	23	388	410	388	410	0.97
7	18	3.7e-07	2.4e-05	24.6	4.3	1	23	416	438	416	438	0.98
8	18	1.3e-07	8.5e-06	26.0	2.4	1	23	444	466	444	466	0.97
9	18	7.6e-05	0.005	17.3	6.7	1	23	473	495	473	495	0.97
10	18	0.00013	0.0086	16.5	6.5	1	23	501	523	501	523	0.98
11	18	1.2e-05	0.00077	19.8	4.5	1	23	529	551	529	551	0.98
12	18	8.6e-06	0.00056	20.3	8.1	1	23	557	579	557	579	0.98
13	18	7e-06	0.00045	20.5	7.6	1	23	585	607	585	607	0.97
14	18	7.8e-07	5.1e-05	23.5	7.7	1	23	613	635	613	635	0.98
15	18	0.00024	0.016	15.7	9.5	1	23	641	664	641	664	0.95
16	18	8.7e-05	0.0056	17.1	0.9	1	23	670	692	670	692	0.98
17	18	0.00095	0.062	13.8	3.4	1	23	702	724	702	724	0.97
18	18	1.1e-05	0.0007	19.9	1.6	1	23	730	753	730	753	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGTCATTGTCCGGTGTCAAATCGGCGGAATCATCGCATAAAGAGGACGGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGGTTCACGGCAGCCAATTGCCACCGCCGCAACTGCCACCGCCGCCCCCCTTACCGCCACAGACGACGCATTCGGCaagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCagcggttgctgctgtaatGGCCTCGgccaatgcagcagcagcggctgcagcagccgcatcagcagcggcatcagcacaacagcaacaacagcaacaacaacagcaacaacagcaacaacaacagcaacaacagcagcaacaacagcaacaacaacagccagcgACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACAACGACCAGCTCGGGCAGCAACGGGGGTGGGAACGGGGGCAACAACTCAACGACAACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCATAGCGAGCGCAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGCGGTCCCATGTTCACGTGCATTGTATGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgtCAAACACCGCATCAATGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCATACGGGCGATTCGCCGCATCGCTGCTCCTACTGCAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAATCATGTGCGCCTGCACACGGGGGACTCGCCGCACAAGTGCGAATACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGTTGCAATGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGTCCCTTTACCTGCGAGACTTGCGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAAGAGTGCGAGCGTCCATTCGCTTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAGGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcggcgacgacgacgatgcaCACCATACAGCAGATAACAGCAGGCGCCGCAGCGGCGGGTGCCGGGGCCGTCCAGTTAGCGCCGGGCCTGGTGCCGCTGGTCACCAGCTCGCTCATCTCGCACAATGCGCAGCAGtcgcagaagcagcagcaggcggcggcagcagttgccgcccaacagcaggcggcagcagcagccgctgcacaGCAACAGGCGGCCGCTGCGGCGGCAGcccagcagcaggcggcggcggcagcagcgcaccagcagcatcagcaacaggtggccgcacaacagcagcaacaacagcagcagcagcaggctgcCGTCGCtgcacatcagcagcagcaacagcagctgcagcagcaacagttgctccaATTGTCCATACAGCAGGCGGCCcaccatcatcagcagcatcagcagcagcagcaacagcagcagcagcatcatcaacagcagcaacagtcgcatcCGCAGGCaccgccacagcagcaacagcaacaacagcagccgccgccacAGGTGCCGATCGCATTGATAAGTGATCCGAGTGCGCTGGCACGTGCCGccatgcagctgcagcatctgCCCACAAATGTGGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVTTGGGTTITLGGPPSLSGVKSAESSHKEDGGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAASAQQQQQQQQQQQQQQQQQQQQQQQQQQQPATSTNAGSQQGSATVTTTSSGSNGGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLAPGLVPLVTSSLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQHHQQQQQSHPQAPPQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -