Dust015549.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ustulata
Gene Symbol
-
Assembly
GCA_035047365.1
Location
JAWNPT010000118.1:3040341-3048625[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.7e-05 0.0018 18.6 2.1 1 23 288 310 288 310 0.97
2 20 8.9e-06 0.0006 20.1 0.4 1 23 316 338 316 338 0.97
3 20 0.0013 0.088 13.3 0.9 1 23 344 366 344 366 0.95
4 20 1.9e-05 0.0013 19.1 3.1 1 23 372 394 372 394 0.97
5 20 4.3e-05 0.0029 18.0 4.7 1 23 400 422 400 422 0.99
6 20 7.8e-05 0.0053 17.2 5.7 1 23 428 450 428 450 0.97
7 20 3.8e-07 2.6e-05 24.4 4.3 1 23 456 478 456 478 0.98
8 20 1.4e-07 9.3e-06 25.8 2.4 1 23 484 506 484 506 0.97
9 20 6.7e-06 0.00045 20.5 4.1 1 23 513 535 513 535 0.97
10 20 5.7e-06 0.00039 20.7 6.7 1 23 541 563 541 563 0.98
11 20 8e-05 0.0054 17.1 6.7 1 23 569 591 569 591 0.97
12 20 0.00014 0.0094 16.4 6.5 1 23 597 619 597 619 0.98
13 20 1.2e-05 0.00084 19.7 4.5 1 23 625 647 625 647 0.98
14 20 9e-06 0.00061 20.1 8.1 1 23 653 675 653 675 0.98
15 20 7.3e-06 0.00049 20.4 7.6 1 23 681 703 681 703 0.97
16 20 8.2e-07 5.5e-05 23.4 7.7 1 23 709 731 709 731 0.98
17 20 0.00026 0.017 15.5 9.5 1 23 737 760 737 760 0.95
18 20 9.1e-05 0.0061 17.0 0.9 1 23 766 788 766 788 0.98
19 20 0.001 0.067 13.7 3.4 1 23 798 820 798 820 0.97
20 20 1.1e-05 0.00077 19.8 1.6 1 23 826 849 826 849 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCCACAAGGGCGGCGATCAGCAGCATCATCTGAATCATCATCAACTGCAGCACCATctgcagcatcatcagcataaTAACAACAGTAAATTGGATAAGCAGCCaacggcggcaacagcagGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAATTATTTACGTATCACGAGGTCTTTGGAAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGTTGCCTCCGCCTCAACTgcctccgccaccgccactgccaccgcaagcagcagcagcatccgcGACGCATTCATCGGCTagcgcagctgcagccgcagcgGCGGTGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCCTCGGCCaatgcagcagccgcagctgcagcggccgcctcagcggcggcaacagcacaacaacagcagcagcagcaacaacagcagcagcaacaacagcagcagcaacagcagcagcaacaacagcagcagcaggttgtGACTAGCACAAATGCTGGAAGCCAACAGGGAAGCGCCACGGTGACGACGACTAGCTCAggtagcaacaacagcgggaATAACAGTGGGGGcaataacagtaacagtaacagcaacaacaataacagttcgacgacgacaacaacaacgaccgGTGGTGAACTGCTGATGCCCAAAATGGAGGGCGGCATTCATGGCGTTGACGGTCAATCGAGCGTTGCCTTGGCCCCCGATGGCACACCGATTGCAACCGGGACGCATGTCTGCGATATTTGTGggaaaatgtttcaatttcGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCATTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGTAAAATTCATATTGGCGGTCCCATGTTCACATGCATTGTCTGCTTCAATGTTTTTGCCAACAACACGAGCTTGGAGCGGCACATGAAACGTCACTCCACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCGCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACCGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCATCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGGAGAATTTGATAAATCACGTGCGCCAGCACACGGGAGAATCGCCGCATCGCTGCTCCTACTGCAGCAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAACCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACGAAGACCTTCACAAGGAAGGAGCACCTAACGAATCATGTGCGCCAGCACACGGGCGATTCGCCGCATCGCTGCTCCTACTGCAAGAAGACCTTCACCCGAAAGGAGCATCTGACGAATCATGTCCGCCTGCACACTGGAGATTCGCCGCACAAGTGCGAATACTGTCAGAAGACCTTCACACGGAAGGAGCATCTCAATAATCACATGCGTCAGCATTCGAGCGACAATCCCCATTGCTGCAATGTGTGCAACAAACCGTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGTTGCCACACCGGCGATCGTCCGTTCACGTGCGAGACATGCGGCAAATCGTTCCCCCTCAAGGGCAATCTGTTGTTCCATCAGCGTAGCCATACCAAGGGACAGGAATGCGAGCGTCCGTTTGCCTGCGAAAAGTGCCCCaagaatttcatttgcaaagGTCACTTGGTCTCGCACATGCGATCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCGCATCATTCGGCGACGACCACAATGCATACCATTCAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCCGGTGCCGTCCAGCTGACCCCAGGCCTGGTGCCGTTGGTCACCAGCTCGCTCATCTCGCACAATGCCCAGCAAacgcagaagcagcagcaagcggCCGCCGCAGTccagcaacaagcagctgctgccgccgcggcacaacagcaacaggcagccgctgcggctgcggctcagcagcaggcagcggCCGTGgcgcatcagcagcatcagcaacaggtggccgcacagcagcagcaacaacagcagcaggctgCCGCGGCtgcacatcagcaacagcagttgcagcagcagcaactgttgcagtTGTCCATACAGCAGGCggcgcatcatcatcagcagcatcagcaacagcagcagcagcaacaacagcagcagcagcaacatcatcagcagcagcagcaggcacatCCGCAGGcaccgccacagcagcaacaacagcaaccgccTCCGCAGGTGCCCATCGCCCTGATCAGTGATCCAAGCGCATTGGCGCGCGCTGCcatgcagctgcaacatttgcCCACGAATGTGGAGCAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGHKGGDQQHHLNHHQLQHHLQHHQHNNNSKLDKQPTAATAGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQAAAASATHSSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQQQQQQQQQQQQQQQQVVTSTNAGSQQGSATVTTTSSGSNNSGNNSGGNNSNSNSNNNNSSTTTTTTTGGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKENLINHVRQHTGESPHRCSYCSKTFTRKEHLVNHIRQHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSSLISHNAQQTQKQQQAAAAVQQQAAAAAAAQQQQAAAAAAAQQQAAAVAHQQHQQQVAAQQQQQQQQAAAAAHQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQQQQHHQQQQQAHPQAPPQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00509230;
80% Identity
-