Dnik003192.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nikananu
Gene Symbol
-
Assembly
GCA_008042635.1
Location
VNJV01002520.1:22105-28557[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.5e-05 0.0017 19.1 2.1 1 23 226 248 226 248 0.97
2 18 5e-06 0.00056 20.6 0.4 1 23 254 276 254 276 0.97
3 18 0.00073 0.082 13.8 0.9 1 23 282 304 282 304 0.95
4 18 1e-05 0.0012 19.6 3.1 1 23 310 332 310 332 0.97
5 18 2.4e-05 0.0027 18.5 4.7 1 23 338 360 338 360 0.99
6 18 4.4e-05 0.0049 17.7 5.7 1 23 366 388 366 388 0.97
7 18 2.1e-07 2.4e-05 24.9 4.3 1 23 394 416 394 416 0.98
8 18 7.6e-08 8.6e-06 26.3 2.4 1 23 422 444 422 444 0.97
9 18 4.5e-05 0.005 17.6 6.7 1 23 451 473 451 473 0.97
10 18 7.8e-05 0.0088 16.9 6.5 1 23 479 501 479 501 0.98
11 18 6.9e-06 0.00078 20.2 4.5 1 23 507 529 507 529 0.98
12 18 5e-06 0.00057 20.6 8.1 1 23 535 557 535 557 0.98
13 18 4.1e-06 0.00046 20.9 7.6 1 23 563 585 563 585 0.97
14 18 4.6e-07 5.2e-05 23.9 7.7 1 23 591 613 591 613 0.98
15 18 0.00014 0.016 16.0 9.5 1 23 619 642 619 642 0.95
16 18 5.1e-05 0.0057 17.5 0.9 1 23 648 670 648 670 0.98
17 18 0.00055 0.063 14.2 3.4 1 23 680 702 680 702 0.97
18 18 6.3e-06 0.00071 20.3 1.6 1 23 708 731 708 731 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGCTCGGTGCCATCAGTTGTAGCCCCCGTTGTGACCACCGGTGGAACGACGATCACCTTGGGCGGCCCACCACCGCTCCCCAAATCGGAGCACAAGGAGGATGGCAAGCCGCCGCACGGCATTGAGATGTACAAGGTTAACATCGAGGACATCTCTCAGCTCTTCACCTATCACGAGGTCTTTGGCAAGATTCATGGCGATGTTGTGAATCATCAATTGGCGGCGGCCCATGGAGGCCAGctgccaccaccgccgccccTTCCACCGCAGGCCACTAGTCATGCGGCCagtgcggcagcagcagccgcagcagcgtcCACAAATAATGCCGCTGTGGCGGCAGTGATGGCCTCCGCcaatgcggcggcggcggcagcagcggctgcatCGGCAGcgggcggcggtggaggaCTGCCACCGGCCACCAGCGGCAATGGGGGCCAGCAGGTGACGGTGACGACGACCAGCAGCTCGACGGCCAGCAGCGGCGGGAGCACCACCAGTGGGGGCACCACGACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGCAGCggcaatggcggcggcggcaacggcggGCAGAACGTGGCGCTGGCGCCGGACGGTACGCCAATTGCGACGGGGACGCACGTCTGCGACATTTGCGGCAAGATGTTCCAGTTCCGGTACCAGCTGATCGTGCACCGGCGCTACCACAGCGAACGGAAACCGTTCATGTGCCAGGTGTGTGGCCAGGGCTTCACCACGTCGCAGGATTTGACGCGCCACGGCAAGATTCACATTGGCGGGCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTCGCTAACAATACGAGCCTGGAGCGGCACATGAAACGGCACTCGACGGACAAACCGTTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCGAAGACGTTTACGCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCACCAGTGTGATGTCTGTGGCAAGAAATATACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGCGGAAAGAGTTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCACACAGCAGGCGAGACGCCGCACCGGTGCGACTTCTGTTCCAAGACGTTTACGCGCAAGGAGCATTTGCTTAACCACGTGCGCCAGCACACGGGAGAGTCGCCACACCGCTGCTCCTACTGCATGAAGACTTTTACGCGCAAGGAGCATCTGGTCAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAGTCGCCGCACAAGTGCACATACTGCACAAAGACGTTTACGCGGAAGGAGCACCTGACGAACCATGTGCGCCAGCACACGGGCGACTCCCCGCACCGCTGCTCCTACTGCAAGAAGACGTTCACGCGGAAGGAGCACCTGACGAACCATGTGCGCCTCCACACGGGCGACTCGCCCCACAAGTGCGAGTACTGCCAGAAGACGTTTACGCGGAAGGAGCATCTCAACAACCATATGCGCCAGCATTCAAGCGACAATCCGCACTGCTGCAATGTCTGCAATAAGCCGTTCACGCGCAAGGAGCACCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGGCCCTTCACCTGCGAGACATGCGGCAAATCGTTTCCGCTCAAGGGCAACCTGCTTTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGAGGCCCTTTGCCTGCGAAAAGTGCCCCAAGAATTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATAACCGCTGGTGCGGCGGGCGCGAACGTGGAGCAACACCCGGTTGTTTACTAA
Protein Sequence
MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSEHKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHGGQLPPPPPLPPQATSHAASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAGGGGGLPPATSGNGGQQVTVTTTSSSTASSGGSTTSGGTTTTAGELLMPKMEGGIHGVDGSGNGGGGNGGQNVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00507738;
80% Identity
iTF_00593957;