Dsia004613.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila siamana
Gene Symbol
-
Assembly
GCA_035047445.1
Location
JAWNPP010000016.1:2166219-2174939[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.7e-05 0.0016 18.6 2.1 1 23 314 336 314 336 0.97
2 20 8.9e-06 0.00054 20.1 0.4 1 23 342 364 342 364 0.97
3 20 0.0013 0.079 13.3 0.9 1 23 370 392 370 392 0.95
4 20 1.9e-05 0.0011 19.1 3.1 1 23 398 420 398 420 0.97
5 20 4.3e-05 0.0026 18.0 4.7 1 23 426 448 426 448 0.99
6 20 7.8e-05 0.0047 17.1 5.7 1 23 454 476 454 476 0.97
7 20 3.8e-07 2.3e-05 24.4 4.3 1 23 482 504 482 504 0.98
8 20 1.4e-07 8.3e-06 25.8 2.4 1 23 510 532 510 532 0.97
9 20 6.6e-06 0.0004 20.5 4.1 1 23 539 561 539 561 0.97
10 20 5.7e-06 0.00035 20.7 6.7 1 23 567 589 567 589 0.98
11 20 8e-05 0.0048 17.1 6.7 1 23 595 617 595 617 0.97
12 20 0.00014 0.0084 16.3 6.5 1 23 623 645 623 645 0.98
13 20 1.2e-05 0.00075 19.6 4.5 1 23 651 673 651 673 0.98
14 20 9e-06 0.00054 20.1 8.1 1 23 679 701 679 701 0.98
15 20 7.3e-06 0.00044 20.4 7.6 1 23 707 729 707 729 0.97
16 20 8.2e-07 4.9e-05 23.4 7.7 1 23 735 757 735 757 0.98
17 20 0.00026 0.015 15.5 9.5 1 23 763 786 763 786 0.95
18 20 9.1e-05 0.0055 16.9 0.9 1 23 792 814 792 814 0.98
19 20 0.00099 0.06 13.7 3.4 1 23 824 846 824 846 0.97
20 20 1.1e-05 0.00068 19.8 1.6 1 23 852 875 852 875 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCCACAAAGGCGGCgatcaacatcagcagcagcaacagcagcagcatcatcatttaaaccatcatcaacagcatctgcagcaacaacagcatcatcagcataaTAACAACAGTAAAGTGGACGGCGGCAATAAgcagccgacaacaacaacagcaacaggagcaccagcaacggcacaCGGCGgcattgaaatgtataaagtGAACATTGAGGATATATCGCAATTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGTTGCCACCGCCACaactgccaccgccaccgccactgcCACCGCAAGCGACAGCAGCATCCGCGACGCATTCATCGGCTagcgcagctgcagccgcagcggcggTGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCCTCGGCCaatgcagcagccgcagctgcagcggccgcATCAGCGGCCgccacacagcaacagcagcaacaacagcagcagcagcaacaacagcaacagcagcagcaacaacaacagcagcagcaacagcagcaggctgtGACTAGCACAAATGCTGGGGCCCAACAGGGCAGCGCCACGGTGACGACGACTAGCTCAGgtagcaacaataacaacagcggGAATAACAGTGGGgccaataataacaataacagtaacagtaacagtaacagcaacaacaataacagttcgacgacgacaacgacaaccggTGAACTGCTGATGCCCAAAATGGAGGGCGGCATTCATGGCGTTGACGGACAATCGAGCGTTGCCTTGGCCCCCGATGGCACGCCGATTGCAACCGGTACGCATGTCTGCGATATTTGTGggaaaatgtttcaatttcGCTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCATTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGTAAAATTCATATTGGCGGTCCCATGTTCACGTGCATTGTGTGCTTCAATGTGTTTGCCAACAACACCAGTTTGGAGCGTCACATGAAACGCCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCGCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGGAGAATTTGATAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCAGCAAGACGTTCACGCGCAAGGAGCACCTGGTGAACCATATACGCCAGCACACGGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACGCGCAAGGAGCACTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAACCATATACGCCAGCACACGGGTGAGACTCCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACGAAGACCTTCACCCGTAAGGAGCACCTAACGAATCATGTGCGCCAGCACACGGGCGATTCGCCGCATCGCTGCTCCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATCTGACCAATCACGTCCGCCTGCACACCGGAGATTCGCCCCACAAATGCGAATACTGTCAGAAGACGTTCACGCGGAAGGAGCATCTCAATAATCACATGCGCCAGCACTCGAGCGACAATCCCCACTGCTGCAACGTGTGCAACAAGCCGTTCACGCGCAAGGAGCATCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGTCCGTTCACCTGCGAGACGTGCGGCAAATCGTTCCCCCTCAAGGGCAACTTGTTGTTCCATCAGCGCAGCCATACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAAAAGTGCCCCaagaattttatttgcaaagGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACGCTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCGCATCACTCGGCGACGACCACAATGCACACCATACAGCAGATCACAGCTGGCGCTGCAGCGGCTGGCGCCGGCGCCGTCCAGCTAACGCCCGGCCTGGTGCCGTTGGTCACCAGCACGCTCATCTCCTCGCACAATGCCCAGCAAacgcagaagcaacagcaagcggCCGCCGCTGTTGCGGCCCAGCAACAGgcggctgccgccgccgcagcccagcagcaacaggcagccgcagcggccgctgcacagcagcaggcagcggcTGTGGCccaccagcagcatcagcaacaggtggccgcacagcagcagcaacaacagcagcaggctgcagtcgcagcccatcagcagcagcaacagcagctgcagcagcagcaactgctgcagttgtcCATACAGCAGGCGGCGcatcatcaccagcagcatcagcagcagcaacagcagcagcagcaacaccatcagcagcagcagcaggcccaTCCGCAGgcgccgccacagcagcagcaacagcagcagccgccgccgcaggTGCCCATCGCTTTGATCAGTGATCCGAGCGCATTGGCGCGCGCCGccatgcagctgcagcatctgcCCACGAATGTGGAGCAGCACCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGHKGGDQHQQQQQQQHHHLNHHQQHLQQQQHHQHNNNSKVDGGNKQPTTTTATGAPATAHGGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQATAASATHSSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATQQQQQQQQQQQQQQQQQQQQQQQQQQQAVTSTNAGAQQGSATVTTTSSGSNNNNSGNNSGANNNNNSNSNSNSNNNNSSTTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKENLINHVRQHTGESPHRCSYCSKTFTRKEHLVNHIRQHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISSHNAQQTQKQQQAAAAVAAQQQAAAAAAAQQQQAAAAAAAQQQAAAVAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQHHQQQQQAHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00509230;
80% Identity
-