Basic Information

Insect: Drosophila testacea
Gene Symbol: -
Assembly: GCA_035043265.1
Location: JAWNND010000661.1:2373465-2380758[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.4e-05 0.0019 18.8 2.1 1 23 276 298 276 298 0.97

2 18 8e-06 0.00061 20.3 0.4 1 23 304 326 304 326 0.97

3 18 0.0012 0.09 13.5 0.9 1 23 332 354 332 354 0.95

4 18 1.7e-05 0.0013 19.3 3.1 1 23 360 382 360 382 0.97

5 18 3.9e-05 0.0029 18.2 4.7 1 23 388 410 388 410 0.99

6 18 7e-05 0.0054 17.4 5.7 1 23 416 438 416 438 0.97

7 18 3.5e-07 2.6e-05 24.6 4.3 1 23 444 466 444 466 0.98

8 18 1.2e-07 9.4e-06 26.0 2.4 1 23 472 494 472 494 0.97

9 18 7.2e-05 0.0055 17.3 6.7 1 23 501 523 501 523 0.97

10 18 0.00013 0.0096 16.6 6.5 1 23 529 551 529 551 0.98

11 18 1.1e-05 0.00085 19.9 4.5 1 23 557 579 557 579 0.98

12 18 8.1e-06 0.00062 20.3 8.1 1 23 585 607 585 607 0.98

13 18 6.6e-06 0.0005 20.6 7.6 1 23 613 635 613 635 0.97

14 18 7.4e-07 5.6e-05 23.6 7.7 1 23 641 663 641 663 0.98

15 18 0.00023 0.018 15.7 9.5 1 23 669 692 669 692 0.95

16 18 8.2e-05 0.0062 17.1 0.9 1 23 698 720 698 720 0.98

17 18 0.0009 0.068 13.9 3.4 1 23 730 752 730 752 0.97

18 18 1e-05 0.00078 20.0 1.6 1 23 758 781 758 781 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.4e-05	0.0019	18.8	2.1	1	23	276	298	276	298	0.97
2	18	8e-06	0.00061	20.3	0.4	1	23	304	326	304	326	0.97
3	18	0.0012	0.09	13.5	0.9	1	23	332	354	332	354	0.95
4	18	1.7e-05	0.0013	19.3	3.1	1	23	360	382	360	382	0.97
5	18	3.9e-05	0.0029	18.2	4.7	1	23	388	410	388	410	0.99
6	18	7e-05	0.0054	17.4	5.7	1	23	416	438	416	438	0.97
7	18	3.5e-07	2.6e-05	24.6	4.3	1	23	444	466	444	466	0.98
8	18	1.2e-07	9.4e-06	26.0	2.4	1	23	472	494	472	494	0.97
9	18	7.2e-05	0.0055	17.3	6.7	1	23	501	523	501	523	0.97
10	18	0.00013	0.0096	16.6	6.5	1	23	529	551	529	551	0.98
11	18	1.1e-05	0.00085	19.9	4.5	1	23	557	579	557	579	0.98
12	18	8.1e-06	0.00062	20.3	8.1	1	23	585	607	585	607	0.98
13	18	6.6e-06	0.0005	20.6	7.6	1	23	613	635	613	635	0.97
14	18	7.4e-07	5.6e-05	23.6	7.7	1	23	641	663	641	663	0.98
15	18	0.00023	0.018	15.7	9.5	1	23	669	692	669	692	0.95
16	18	8.2e-05	0.0062	17.1	0.9	1	23	698	720	698	720	0.98
17	18	0.0009	0.068	13.9	3.4	1	23	730	752	730	752	0.97
18	18	1e-05	0.00078	20.0	1.6	1	23	758	781	758	781	0.96

Sequence Information

Coding Sequence: atGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACGTTGGGCGGACCGCCTCCATTGCCATTACTGCATAATAAAGGCGATaatcatcagcagcatcatcataaagaggaacaacagcaacagcatcaacagcaaggCGGCAACATTaataagcaacagcagcagcaaccaccaCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGTTGCCACCGCCACAactgccaccgccaccgccactgCCACCGCAGACGACGCATTCGGCAAgcgcagctgcagcagcagcggcggcgTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCTTCGGCcaatgcagcagcagcggctgcAGCCGCATCAGCAGCGGCATCagctcagcaacaacagcaacaacagcaacaacaacagcaacaacagcaagcgCAAGTGACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACCACGACTAGCTCAGGTAGCAAcggcaataacaataataatgggggtaataataataatgggagcaacaataataataacaataatacgACATCGACAACATCGACGGGTGAATTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGTCAGTCGAGCGTTTCGTTGGCGCCGGATGGCACGCCCATTGCAACTGGTACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAATTTCGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGTAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAAATCCATATTGGCGGTCCCATGTTCACCTGCATTGTTTGCTTCAATGTGTTTGCCAATAATACAAGTTTGGAGAGACATATGAAAAGGCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACTCGCAAGGAGCATCTAGCCAACCACATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAACCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACGAAGACGTTTACCCGTAAGGAGCATCTGACGAATCATGTGCGTCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGTAAGAAGACGTTTACCCGGAAGGAGCATCTGACGAATCATGTGCGCCTACACACTGGAGATTCGCCCCATAAGTGCGAGTATTGCCAGAAGACCTTTACACGCAAGGAGCATCTCAATAACCATATGCGTCAGCATTCAAGCGACAATCCCCATTGTTGCAACGTTTGCAACAAGCCCTTCACCCGCAAGGAGCATCTGATCAATCACATGTCACGCTGTCACACTGGCGATCGTCCCTTCACCTGCGAGACATGCGGCAAATCTTTCCCCCTCAAGGGTAATCTACTTTTCCATCAGCGCAGCCATACCAAGGGTCAAGAGTGCGAACGTCCGTTTGCCTGCGAAAAATGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGAGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCAGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCactcgacaacgacaacaatgcaCACCATCCAACAAATAACAGCTGGAGCTGCTGCAGCTGGAGCCGGTGCCGTCCAGTTAACGCCCGGTTTGGTGCCTCTGGTCACGAGCACGCTCATCTCGCACAATGCGCAATcgcagaagcaacagcaggcggcagcagcagttgctgcacAACAGcaagcggcagcagcagccgctgcACAGCAACAGGCAGCCGCAGCGGCGGCCGCACAACAAcaggcggcagcagcagcacatcaacagcatcagcaacaggttgctgcacagcagcaacaacaacagcaacaggcagcCGCAACgccccagcagcagcaacaacaacagccaccgCCACAGGTGCCCATTGCATTGATAAGTGATCCAAGCGCATTGGCACGGGCTGccatgcaactgcaacatctGCCCACCAATGTTGAACAACATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPLLHNKGDNHQQHHHKEEQQQQHQQQGGNINKQQQQQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAASAAASAQQQQQQQQQQQQQQQAQVTSTNAGSQQGSATVTTTSSGSNGNNNNNGGNNNNGSNNNNNNNTTSTTSTGELLMPKMEGGIHGVDGQSSVSLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSTTTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAATPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00583836;
80% Identity: -