Dari011581.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila arizonae
Gene Symbol
-
Assembly
GCA_001654025.1
Location
NW:15777463-15793193[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.00082 0.046 13.6 3.7 1 21 237 257 237 259 0.94
2 18 6.4e-06 0.00036 20.3 0.4 1 23 265 287 265 287 0.97
3 18 0.00094 0.053 13.5 0.9 1 23 293 315 293 315 0.95
4 18 1.3e-05 0.00075 19.3 3.1 1 23 321 343 321 343 0.97
5 18 3.1e-05 0.0017 18.1 4.7 1 23 349 371 349 371 0.99
6 18 5.6e-05 0.0031 17.3 5.7 1 23 377 399 377 399 0.97
7 18 2.7e-07 1.5e-05 24.6 4.3 1 23 405 427 405 427 0.98
8 18 9.8e-08 5.5e-06 26.0 2.4 1 23 433 455 433 455 0.97
9 18 5.7e-05 0.0032 17.3 6.7 1 23 462 484 462 484 0.97
10 18 0.0001 0.0056 16.5 6.5 1 23 490 512 490 512 0.98
11 18 8.9e-06 0.0005 19.8 4.5 1 23 518 540 518 540 0.98
12 18 6.4e-06 0.00036 20.3 8.1 1 23 546 568 546 568 0.98
13 18 5.2e-06 0.00029 20.5 7.6 1 23 574 596 574 596 0.97
14 18 5.9e-07 3.3e-05 23.5 7.7 1 23 602 624 602 624 0.98
15 18 0.00018 0.01 15.7 9.5 1 23 630 653 630 653 0.95
16 18 6.5e-05 0.0036 17.1 0.9 1 23 659 681 659 681 0.98
17 18 0.00071 0.04 13.8 3.4 1 23 691 713 691 713 0.97
18 18 8.1e-06 0.00046 20.0 1.6 1 23 719 742 719 742 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCAGATCATAAAGAGGACGGCAGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGCAAAATCCACGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGTTGCCACCGCCGCAAttgccgccaccaccgccattACCACCGCAGACGACGCATTCGGCtagcgcagctgcagctgcagcggcggtGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCGGCCAATGCAGCAGCCgcggctgcagcggccgcATCGGCCGCGGCTACggcccaacagcaacaacagcagcagcagcaacagcaagcccCAGCGACAAGCGCAAATGCTGGAACCACCCAGCAGGGCAGCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAATgggggcaacaacaatgcgacgacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCGTTGATGGGCAATCGAGCGTTGCGTTGGCGCCAGATGGCACGCCTATAGCAACTGGGACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTGCCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGCCCCATGTTCACATGCATTGTCTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCACATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCATGTGCGGCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAACCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTGCGCCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAACACTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCATTCTAGCGACAATCCCCATTGCTGCAACGTGTGCAACAAGCCCTTCACACGCAAGGAGCACTTGATTAATCACATGTCGCGCTGTCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGCGGCAAATCGTTCCCCCTCAAGGGCAACCTCCTCTTCCATCAGCGCAGCCACACCAAGGGTCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGCCCCAagaatttcatatgcaaagGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCATTCGGCGACGACCACAATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCTGGTGCCGTCCAGCTGACGCCCGGCCTGGTGCCGCTCGTCACCAGCACCCTCATCTCCCATAATGCCCAGCAGtcgcagaagcagcagcagcaagtggctgctgcagttgctgcccagcagcaggcggcagcagcagccgctgcccaGCAACAGGCAGCCGCGGCGGCCCAGCAGcaagcggcggcggcagcagcacaccagcagcatcagcaacaggtggccgcacagcagcaacaacaacagcagcaggcagcagttgctgcacaccagcagcagcaacagcaactgcagcagcaacagttgttgcaattgtcCATACAGCAGGCggcgcatcatcatcagcagcaacagcagcatcaacagcaacaacagcagcagcagcaacaacaacagcagcaacagcaacagcagcaacatcatccaCAGCAACAAGCGCATCCACAAGcgccgccacagcagcagcaacagcaacagccaccacCGCAGGTGCCCATTGCATTGATAAGTGATCCAAGCGCGCTGGCTCGTGCCGCCATGCAGTTGCAGCATCTGCCAACAAACGTAGAGCAGCATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQAPATSANAGTTQQGSATVTTTSSSGSNGGNGGNNNATTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRCHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQQVAAAVAAQQQAAAAAAAQQQAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQQQHQQQQQQQQQQQQQQQQQQQHHPQQQAHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY