Dnig011396.1
Basic Information
- Insect
- Drosophila nigricruria
- Gene Symbol
- -
- Assembly
- GCA_037075265.1
- Location
- JBAMCI010000150.1:16534733-16541831[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 2.5e-05 0.0018 18.8 2.1 1 23 238 260 238 260 0.97 2 18 8.1e-06 0.00058 20.3 0.4 1 23 266 288 266 288 0.97 3 18 0.0012 0.086 13.5 0.9 1 23 294 316 294 316 0.95 4 18 1.7e-05 0.0012 19.3 3.1 1 23 322 344 322 344 0.97 5 18 3.9e-05 0.0028 18.1 4.7 1 23 350 372 350 372 0.99 6 18 7.1e-05 0.0051 17.3 5.7 1 23 378 400 378 400 0.97 7 18 3.5e-07 2.5e-05 24.6 4.3 1 23 406 428 406 428 0.98 8 18 1.3e-07 9e-06 26.0 2.4 1 23 434 456 434 456 0.97 9 18 7.3e-05 0.0052 17.3 6.7 1 23 463 485 463 485 0.97 10 18 0.00013 0.0091 16.5 6.5 1 23 491 513 491 513 0.98 11 18 1.1e-05 0.00081 19.8 4.5 1 23 519 541 519 541 0.98 12 18 8.2e-06 0.00059 20.3 8.1 1 23 547 569 547 569 0.98 13 18 6.7e-06 0.00048 20.5 7.6 1 23 575 597 575 597 0.97 14 18 7.5e-07 5.4e-05 23.5 7.7 1 23 603 625 603 625 0.98 15 18 0.00023 0.017 15.7 9.5 1 23 631 654 631 654 0.95 16 18 8.3e-05 0.0059 17.1 0.9 1 23 660 682 660 682 0.98 17 18 0.00091 0.065 13.8 3.4 1 23 692 714 692 714 0.97 18 18 1e-05 0.00074 20.0 1.6 1 23 720 743 720 743 0.96
Sequence Information
- Coding Sequence
- ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCTGATCATAAAGAGGACGGCAGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGCAAGATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGCTGCCACCGCCGCAAttgccgccaccaccgccattACCGCCGCAGACGACGCATTCGGCTagcgcagctgcagctgcagcggcggTGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCTTCGGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCCTCGGCCGCGGCCACggcccaacagcaacagcagcagcagcaacaacagcaacagcaagccCCAGCGACAAGCACAAATGCTGGAACACAGCAGGGCAGCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAATgggggcaacaacaatgcgacaacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCGTTGATGGGCAATCGAGCGTTGCGTTGGCGCCAGATGGCACGCCCATAGCGACTGGGACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGTCCCATGTTCACTTGCATTGTCTGCTTCAATGTGTTTGCCAACAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTCCGCCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAGTGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGCTGCAACGTGTGCAACAAGCCCTTCACGCGCAAGGAGCACTTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACTTGCGGCAAATCCTTCCCCCTCAAGGGCAATCTCCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCATTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCATTCGGCGACGACCACAATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCTGGTGCCGTCCAGCTGACGCCCGGCCTGGTGCCGCTCGTCACCAGCACGCTCATCTCCCATAATGCCCAGCAGtcgcagaagcagcagcagcaggtggctgctgcagttgctgcccaACAgcaggcggcggcagcagccgctgcccaACAACAggccgcagccgcagcggctCAGCAGcaagcggcagcggcagcagcgcaccagcagcatcagcaacaggtggccgcacagcagcagcaacaacaacaacaggcagcagttgctgcacatcagcagcagcaacagcaactgcagcagcaacaattgttgcAATTGTCCATACAGCAGGCGgcgcatcatcatcagcagcaacaacagcagcatcaacagcaacagcagcagcagcaacaacagcagcagcaacatcatccaCAGCAACAGTCGCATCCGCAGGCgccgccacagcagcagcagcaacaacagcaacagccaccgCCACAGGTGCCCATTGCATTGATAAGTGATCCGAGCGCGCTGGCTCGTGCCGCCATGCAGTTGCAGCATCTGCCCACAAATGTGGAACAGCATCCGGTGGTTTACTAA
- Protein Sequence
- MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQQQAPATSTNAGTQQGSATVTTTSSSGSNGGNGGNNNATTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQQVAAAVAAQQQAAAAAAAQQQAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQQQQHQQQQQQQQQQQQQHHPQQQSHPQAPPQQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00560429;
- 90% Identity
- iTF_00479608;
- 80% Identity
- -