Basic Information

Insect: Drosophila borealis
Gene Symbol: -
Assembly: GCA_035045885.1
Location: JAWNOR010000018.1:201344-208483[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.5e-05 0.002 18.8 2.1 1 23 233 255 233 255 0.97

2 18 8.1e-06 0.00066 20.3 0.4 1 23 261 283 261 283 0.97

3 18 0.0012 0.097 13.5 0.9 1 23 289 311 289 311 0.95

4 18 1.7e-05 0.0014 19.3 3.1 1 23 317 339 317 339 0.97

5 18 3.9e-05 0.0032 18.2 4.7 1 23 345 367 345 367 0.99

6 18 7.1e-05 0.0058 17.3 5.7 1 23 373 395 373 395 0.97

7 18 3.5e-07 2.8e-05 24.6 4.3 1 23 401 423 401 423 0.98

8 18 1.2e-07 1e-05 26.0 2.4 1 23 429 451 429 451 0.97

9 18 7.3e-05 0.0059 17.3 6.7 1 23 458 480 458 480 0.97

10 18 0.00013 0.01 16.5 6.5 1 23 486 508 486 508 0.98

11 18 1.1e-05 0.00092 19.8 4.5 1 23 514 536 514 536 0.98

12 18 8.2e-06 0.00067 20.3 8.1 1 23 542 564 542 564 0.98

13 18 6.7e-06 0.00054 20.6 7.6 1 23 570 592 570 592 0.97

14 18 7.5e-07 6.1e-05 23.6 7.7 1 23 598 620 598 620 0.98

15 18 0.00023 0.019 15.7 9.5 1 23 626 649 626 649 0.95

16 18 8.3e-05 0.0067 17.1 0.9 1 23 655 677 655 677 0.98

17 18 0.0009 0.074 13.9 3.4 1 23 687 709 687 709 0.97

18 18 1e-05 0.00084 20.0 1.6 1 23 715 738 715 738 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.5e-05	0.002	18.8	2.1	1	23	233	255	233	255	0.97
2	18	8.1e-06	0.00066	20.3	0.4	1	23	261	283	261	283	0.97
3	18	0.0012	0.097	13.5	0.9	1	23	289	311	289	311	0.95
4	18	1.7e-05	0.0014	19.3	3.1	1	23	317	339	317	339	0.97
5	18	3.9e-05	0.0032	18.2	4.7	1	23	345	367	345	367	0.99
6	18	7.1e-05	0.0058	17.3	5.7	1	23	373	395	373	395	0.97
7	18	3.5e-07	2.8e-05	24.6	4.3	1	23	401	423	401	423	0.98
8	18	1.2e-07	1e-05	26.0	2.4	1	23	429	451	429	451	0.97
9	18	7.3e-05	0.0059	17.3	6.7	1	23	458	480	458	480	0.97
10	18	0.00013	0.01	16.5	6.5	1	23	486	508	486	508	0.98
11	18	1.1e-05	0.00092	19.8	4.5	1	23	514	536	514	536	0.98
12	18	8.2e-06	0.00067	20.3	8.1	1	23	542	564	542	564	0.98
13	18	6.7e-06	0.00054	20.6	7.6	1	23	570	592	570	592	0.97
14	18	7.5e-07	6.1e-05	23.6	7.7	1	23	598	620	598	620	0.98
15	18	0.00023	0.019	15.7	9.5	1	23	626	649	626	649	0.95
16	18	8.3e-05	0.0067	17.1	0.9	1	23	655	677	655	677	0.98
17	18	0.0009	0.074	13.9	3.4	1	23	687	709	687	709	0.97
18	18	1e-05	0.00084	20.0	1.6	1	23	715	738	715	738	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCGGACCGCCGCCATTGCCCAACAGCAAATCAGATCATAAAGAGGACGGCAACAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGCTGCCACCGCCGCAgctgccaccgccaccgccactACCGCCGCAGACGACGCATTCGGCTagcgcagctgcagcagcagcggcggcgaccACAAATAATGCAGCCGTCGCTGCTGTAATGGCTTCGGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCCTCAGTAGCGGCCACagcccaacagcaacagcagcaacagcaagccCCAGCGACAAGCACAAATGCTGGATCACAACAGGGCAGCGCCACGGTGACCACGACTAGCTCCGGCAGCAACGGGGGGAAtgggggcaacaacaacaactcgacaacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGGCAATCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATAGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTCATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGGCATGGGAAGATCCACATTGGCGGTCCCATGTTCACTTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAAAGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGTCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTTAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTTCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCATTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACGAATCATGTGCGACAGCACACGGGCGATTCGCCGCACCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGTCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAACCATATGCGCCAGCACTCGAGCGACAATCCCCACTGTTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCATTTGATTAATCATATGTCCCGTTGCCACACCGGCGATCGTCCTTTCACCTGCGAGACGTGCGGTAAATCGTTTCCCCTCAAGGGTAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCGTTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACCACGATGCACACCATTCAGCAGATAACAGCGGGCGCAGCAGCGGCTGGCGCCGGTGCCGTCCAGTTAACGCCTGGCTTGGTGCCGCTTGTCACCAGCACGCTCATCTCGCACAATGCCCAGCAGtcgcagaagcagcagcaggcggccgCAGCAGTTGCCGCACAACAgcaggcggcggcagcagccgctgcccagcaacaggcggcggcggctcaacaacaagcggcagcagcagcgcatcagcaacatcagcaacaagtggccgcacagcagcaacaacagcaacagcaggcggcAGTCGCTgcacatcagcagcagcaacagcaactgcagcagcaacagttgctgcaatTGTCCATACAGCATGCGGCGCatcatcaccagcagcagcatcaacagcagcagcaacagcagcagcaacatcatcaacagcaacaacaacaacagtcgcATCCACAGGCGCCGcctcagcaacaacagcagcagcagccaccacCACAGGTGCCAATTGCATTGATAAGTGATCCAAGCGCGCTGGCGCGTGCCGCGATGCAACTGCAGCATCTGCCCACAAATGTGGAGCAACATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPNSKSDHKEDGNKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAATTNNAAVAAVMASANAAAAAAAAASVAATAQQQQQQQQAPATSTNAGSQQGSATVTTTSSGSNGGNGGNNNNSTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQHAAHHHQQQHQQQQQQQQQHHQQQQQQQSHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -