Basic Information

Insect: Drosophila navojoa
Gene Symbol: -
Assembly: GCA_001654015.2
Location: NW:75032-88608[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00083 0.048 13.6 3.7 1 21 237 257 237 259 0.94

2 18 6.4e-06 0.00037 20.3 0.4 1 23 265 287 265 287 0.97

3 18 0.00095 0.054 13.5 0.9 1 23 293 315 293 315 0.95

4 18 1.4e-05 0.00078 19.3 3.1 1 23 321 343 321 343 0.97

5 18 3.1e-05 0.0018 18.1 4.7 1 23 349 371 349 371 0.99

6 18 5.7e-05 0.0032 17.3 5.7 1 23 377 399 377 399 0.97

7 18 2.8e-07 1.6e-05 24.6 4.3 1 23 405 427 405 427 0.98

8 18 9.9e-08 5.7e-06 26.0 2.4 1 23 433 455 433 455 0.97

9 18 5.8e-05 0.0033 17.3 6.7 1 23 462 484 462 484 0.97

10 18 0.0001 0.0058 16.5 6.5 1 23 490 512 490 512 0.98

11 18 9e-06 0.00052 19.8 4.5 1 23 518 540 518 540 0.98

12 18 6.5e-06 0.00037 20.3 8.1 1 23 546 568 546 568 0.98

13 18 5.3e-06 0.0003 20.5 7.6 1 23 574 596 574 596 0.97

14 18 5.9e-07 3.4e-05 23.5 7.7 1 23 602 624 602 624 0.98

15 18 0.00019 0.011 15.7 9.5 1 23 630 653 630 653 0.95

16 18 6.6e-05 0.0038 17.1 0.9 1 23 659 681 659 681 0.98

17 18 0.00072 0.041 13.8 3.4 1 23 691 713 691 713 0.97

18 18 8.2e-06 0.00047 19.9 1.6 1 23 719 742 719 742 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00083	0.048	13.6	3.7	1	21	237	257	237	259	0.94
2	18	6.4e-06	0.00037	20.3	0.4	1	23	265	287	265	287	0.97
3	18	0.00095	0.054	13.5	0.9	1	23	293	315	293	315	0.95
4	18	1.4e-05	0.00078	19.3	3.1	1	23	321	343	321	343	0.97
5	18	3.1e-05	0.0018	18.1	4.7	1	23	349	371	349	371	0.99
6	18	5.7e-05	0.0032	17.3	5.7	1	23	377	399	377	399	0.97
7	18	2.8e-07	1.6e-05	24.6	4.3	1	23	405	427	405	427	0.98
8	18	9.9e-08	5.7e-06	26.0	2.4	1	23	433	455	433	455	0.97
9	18	5.8e-05	0.0033	17.3	6.7	1	23	462	484	462	484	0.97
10	18	0.0001	0.0058	16.5	6.5	1	23	490	512	490	512	0.98
11	18	9e-06	0.00052	19.8	4.5	1	23	518	540	518	540	0.98
12	18	6.5e-06	0.00037	20.3	8.1	1	23	546	568	546	568	0.98
13	18	5.3e-06	0.0003	20.5	7.6	1	23	574	596	574	596	0.97
14	18	5.9e-07	3.4e-05	23.5	7.7	1	23	602	624	602	624	0.98
15	18	0.00019	0.011	15.7	9.5	1	23	630	653	630	653	0.95
16	18	6.6e-05	0.0038	17.1	0.9	1	23	659	681	659	681	0.98
17	18	0.00072	0.041	13.8	3.4	1	23	691	713	691	713	0.97
18	18	8.2e-06	0.00047	19.9	1.6	1	23	719	742	719	742	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCTCCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCAGATCATAAAGAGGACGGCAGCAAGCCGCCGCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGCAAAATCCACGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGCCAGTTGCCACCGCCGCAAttgccgccaccaccgccattACCACCGCAGACGACGCATTCGGCtagcgcagctgcagctgcagcggcggtGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCGGCCAATGCAGCAGCCgcggctgcagcggccgcATCGGCTGCGGCCAcggcccagcagcaacaacagcagcaacagcaacagcaagcccCAGCGACAAGCGCAAATGCTGGAACCACCCAGCAGGGCAGCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAATgggggcaacaacaatgcgacgacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCGTTGATGGGCAATCGAGCGTTGCGTTGGCGCCAGACGGCACGCCTATAGCAACTGGTACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTGCCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGCCCCATGTTCACATGCATTGTCTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACACCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTCAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTCCGCCAGCATACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGCAAGGAACACTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCTAGCGACAATCCGCATTGCTGCAACGTGTGCAACAAGCCCTTCACACGCAAGGAGCACTTGATCAATCACATGTCGCGTTGTCACACCGGCGATCGCCCCTTCACCTGCGAGACATGCGGCAAATCGTTCCCCCTCAAGGGCAACCTCCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGCCCCAagaatttcatatgcaaagGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCATTCGGCGACGACCACAATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCTGGTGCTGTCCAGCTGACGCCCGGCCTGGTGCCGCTCGTCACCAGCACGCTCATCTCCCATAATGCCCAGCAGtcgcagaagcagcagcagcaagtggctgctgcagttgctgcccagcagcaggcggcggcagcggccgcTGCCCAGCAACAGGCAGCCGCGGCGGCTCAACAGcaagcggcggcggcagcagcacaccagcagcatcagcaacaggtggccgcacagcagcaacaacagcagcagcaggcagcagttgctgcacaccagcagcagcaacagcaactgcagcagcaacaactgttgcaaTTGTCCATACAGCAGGCggcgcatcatcatcagcagcaacagcagcatcaacagcaacaacagcagcagcagcagcagcagcagcaacaacaacaacaacagcaacagcagcagcagcaacatcatccaCAGCAACAAGCGCATCCACAAGcgccgccacagcagcagcaacagccaccacCGCAGGTGCCCATTGCATTGATAAGTGATCCAAGCGCGCTGGCTCGTGCCGCCATGCAGTTGCAGCATCTGCCCTCAAATGTGGAGCAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTISLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQAPATSANAGTTQQGSATVTTTSSSGSNGGNGGNNNATTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRCHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQQVAAAVAAQQQAAAAAAAQQQAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQHHPQQQAHPQAPPQQQQQPPPQVPIALISDPSALARAAMQLQHLPSNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00479608;
80% Identity: -