Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000401.1:1166401-1173697[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.5e-05 0.0019 18.7 2.1 1 23 279 301 279 301 0.97

2 18 8.2e-06 0.00063 20.2 0.4 1 23 307 329 307 329 0.97

3 18 0.0012 0.093 13.4 0.9 1 23 335 357 335 357 0.95

4 18 1.7e-05 0.0013 19.2 3.1 1 23 363 385 363 385 0.97

5 18 4e-05 0.003 18.1 4.7 1 23 391 413 391 413 0.99

6 18 7.2e-05 0.0055 17.3 5.7 1 23 419 441 419 441 0.97

7 18 3.6e-07 2.7e-05 24.5 4.3 1 23 447 469 447 469 0.98

8 18 1.3e-07 9.7e-06 25.9 2.4 1 23 475 497 475 497 0.97

9 18 7.4e-05 0.0057 17.2 6.7 1 23 504 526 504 526 0.97

10 18 0.00013 0.0099 16.5 6.5 1 23 532 554 532 554 0.98

11 18 1.2e-05 0.00088 19.8 4.5 1 23 560 582 560 582 0.98

12 18 8.4e-06 0.00064 20.2 8.1 1 23 588 610 588 610 0.98

13 18 6.8e-06 0.00052 20.5 7.6 1 23 616 638 616 638 0.97

14 18 7.6e-07 5.8e-05 23.5 7.7 1 23 644 666 644 666 0.98

15 18 0.00024 0.018 15.6 9.5 1 23 672 695 672 695 0.95

16 18 8.4e-05 0.0064 17.1 0.9 1 23 701 723 701 723 0.98

17 18 0.00092 0.071 13.8 3.4 1 23 733 755 733 755 0.97

18 18 1.1e-05 0.0008 19.9 1.6 1 23 761 784 761 784 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.5e-05	0.0019	18.7	2.1	1	23	279	301	279	301	0.97
2	18	8.2e-06	0.00063	20.2	0.4	1	23	307	329	307	329	0.97
3	18	0.0012	0.093	13.4	0.9	1	23	335	357	335	357	0.95
4	18	1.7e-05	0.0013	19.2	3.1	1	23	363	385	363	385	0.97
5	18	4e-05	0.003	18.1	4.7	1	23	391	413	391	413	0.99
6	18	7.2e-05	0.0055	17.3	5.7	1	23	419	441	419	441	0.97
7	18	3.6e-07	2.7e-05	24.5	4.3	1	23	447	469	447	469	0.98
8	18	1.3e-07	9.7e-06	25.9	2.4	1	23	475	497	475	497	0.97
9	18	7.4e-05	0.0057	17.2	6.7	1	23	504	526	504	526	0.97
10	18	0.00013	0.0099	16.5	6.5	1	23	532	554	532	554	0.98
11	18	1.2e-05	0.00088	19.8	4.5	1	23	560	582	560	582	0.98
12	18	8.4e-06	0.00064	20.2	8.1	1	23	588	610	588	610	0.98
13	18	6.8e-06	0.00052	20.5	7.6	1	23	616	638	616	638	0.97
14	18	7.6e-07	5.8e-05	23.5	7.7	1	23	644	666	644	666	0.98
15	18	0.00024	0.018	15.6	9.5	1	23	672	695	672	695	0.95
16	18	8.4e-05	0.0064	17.1	0.9	1	23	701	723	701	723	0.98
17	18	0.00092	0.071	13.8	3.4	1	23	733	755	733	755	0.97
18	18	1.1e-05	0.0008	19.9	1.6	1	23	761	784	761	784	0.96

Sequence Information

Coding Sequence: atGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACGTTGGGCGGACCGCCTCCATTGCCATTACTGCATAATAAGGGCGATaatcatcagcagcatcatcataaagaggaacaacagcaacagcaacaacagcaaggcGGCAACATTAAtaagcaacagcatcagcaacctCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGTTGCCACCGCCACAactgccaccgccaccgccactACCACCGCAGACGACGCATTCGGCAAgcgcagctgcagcagcagcggcggcgtCCACAAATAATGCAGCTGTCGCTGCTGTAATGGCTTCGGccaatgcagcagcagcggctgcAGCCGCATCAGCAGCGGCATCagctcagcaacaacagcaacaacagcaacaacaacagcaacaacagcaagcgCAAGTGACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACCACGACTAGCTCAGGTAGCAacggcaataacaataataatgggggtaataataataataatgggagcaacaataataataataataacaataatacgACATCGACAACATCGACGGGTGAATTGCTAATGCCGAAAATGGAGGGCGGCATTCATGGCGTCGATGGTCAGTCGAGCGTTTCGTTGGCGCCGGATGGCACGCCCATTGCAACTGGTACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAATTTCGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGTAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAAATCCATATTGGCGGTCCCATGTTCACCTGCATTGTTTGCTTCAATGTGTTTGCCAATAATACAAGTTTGGAGAGACATATGAAAAGGCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACTCGCAAGGAGCATCTAGCCAATCACATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACGAAGACGTTTACCCGTAAGGAGCATCTGACGAATCATGTGCGTCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGTAAGAAGACGTTTACCCGGAAGGAGCATCTGACGAATCATGTGCGCCTACACACTGGAGATTCGCCCCATAAGTGCGAGTATTGCCAGAAGACCTTTACACGCAAGGAGCATCTCAATAACCATATGCGTCAGCATTCAAGCGACAATCCCCATTGTTGCAACGTTTGCAACAAGCCCTTCACCCGCAAGGAGCATCTGATCAATCACATGTCACGCTGTCACACCGGCGATCGTCCCTTCACCTGCGAGACATGCGGCAAATCTTTCCCCCTCAAGGGTAATCTACTTTTCCATCAGCGCAGCCATACCAAGGGTCAAGAGTGCGAACGTCCGTTTGCCTGCGAAAAATGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGAGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCAGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcgacgacgacaacaatgCACACCATACAACAGATAACAGCTGGAGCTGCTGCAGCTGGAGCCGGTGCCGTCCAGTTAACGCCCGGTTTGGTGCCTCTGGTCACGAGCACGCTCATCTCGCACAATGCGCAATcgcagaagcaacagcaggcggcagcagcagttgctgcacAACAGcaagcggcagcagcagccgctgcACAGCAACAGGCAGCCGCAGCGGCGGCCGCACAACAacaggcggcagcagcagcacatcaacagcatcagcaacaggttgctgcacagcagcaacaacaacagcaacaggcagcCGTAGCAgcacatcagcagcagcaacaacagttgcagcagcagcaattgctgcaGTTGTCAATACAACAGGCCgcccatcatcatcaacaacatcagcagcaacaacagcagcagcagcaacatcatcagcagcaacaacaacaggctcACCCCCAGGCaccaccacagcagcagcaacaacaacagccaccgCCACAGGTGCCGATTGCATTGATAAGTGATCCAAGTGCATTGGCACGGGCTGccatgcaactgcaacatctgCCCACCAATGTTGAACAACATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPLLHNKGDNHQQHHHKEEQQQQQQQQGGNINKQQHQQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAASAAASAQQQQQQQQQQQQQQQAQVTSTNAGSQQGSATVTTTSSGSNGNNNNNGGNNNNNGSNNNNNNNNNTTSTTSTGELLMPKMEGGIHGVDGQSSVSLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSTTTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQHHQQQQQQAHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -