Dins012994.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila insularis
Gene Symbol
-
Assembly
GCA_018903935.1
Location
JAEIFP010001084.1:7544671-7552152[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.6e-05 0.0013 19.1 2.1 1 23 231 253 231 253 0.97
2 18 5.3e-06 0.00042 20.6 0.4 1 23 259 281 259 281 0.97
3 18 0.00079 0.062 13.8 0.9 1 23 287 309 287 309 0.95
4 18 1.1e-05 0.00089 19.6 3.1 1 23 315 337 315 337 0.97
5 18 2.6e-05 0.002 18.5 4.7 1 23 343 365 343 365 0.99
6 18 4.7e-05 0.0037 17.7 5.7 1 23 371 393 371 393 0.97
7 18 2.3e-07 1.8e-05 24.9 4.3 1 23 399 421 399 421 0.98
8 18 8.3e-08 6.5e-06 26.3 2.4 1 23 427 449 427 449 0.97
9 18 4.8e-05 0.0038 17.6 6.7 1 23 456 478 456 478 0.97
10 18 8.4e-05 0.0066 16.9 6.5 1 23 484 506 484 506 0.98
11 18 7.5e-06 0.00059 20.2 4.5 1 23 512 534 512 534 0.98
12 18 5.4e-06 0.00043 20.6 8.1 1 23 540 562 540 562 0.98
13 18 4.4e-06 0.00035 20.9 7.6 1 23 568 590 568 590 0.97
14 18 4.9e-07 3.9e-05 23.9 7.7 1 23 596 618 596 618 0.98
15 18 0.00015 0.012 16.0 9.5 1 23 624 647 624 647 0.95
16 18 5.5e-05 0.0043 17.5 0.9 1 23 653 675 653 675 0.98
17 18 0.00058 0.046 14.2 4.4 1 23 685 707 685 707 0.98
18 18 6.8e-06 0.00054 20.3 1.6 1 23 713 736 713 736 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTAAGCGCTGCCAGTTCGGTACCATCGGTAATTGCACCGGTGGTTACCACTGGAGGCACCACCATTACCTTGGGCGGTGGACCACCACCGCCATCCTCATCATTGGCCAAATCGGAGATTAAAGAAGATGGCAAACCGCCACATGGCATGGAACTGTATAAAGTGAACATTGAGGATATTTCGCAATTGTTTACATATCATGAAGTCTTTGGCAAAATACATGGAGATGTTGTCAATCATCAATTGGTGGCAGCGGCACATGGTGGACAATTGCCACCGCCACCACCGTTGCCGCCTCAGACGCATGCCTCGAGTGCTGCGGCAGCCGCGGCGGCGGCAGCAGCCACAACAAATAATGCAGCCGTGGCTGCTGTAATGGCATCCGCGAATGCAGCAGCAGCGGCGGCAGCTGCCGCATCAGCCGCTGGTGGAGTACCCTCCACTACGAGTAGTGTGGGCGGTGGTGGAATACCGGGAGTAGTTACAACCACAACAAGCTCATCCACCGGAAGCAGTGGCGGCGCTAGTGGTGCCGCCGGCGGGGGTACCACATCGAGCACAACGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCCTACATGGCAACGTGGACGCTGGTGGCGGCGGTCAAACCCAGGTGGCCCTAGCCCCTGATGGCACCCCAATTGCCACGGGGACGCATGTCTGCGATATATGTGGCAAGATGTTCCAGTTTCGTTATCAGCTTATTGTCCATCGTCGCTATCATAGCGAACGGAAACCGTTTATGTGTCAGGTTTGCGGTCAGGGTTTTACCACATCGCAGGATCTGACACGACATGGTAAAATCCATATTGGCGGACCGATGTTCACCTGCATCGTTTGCTTCAATGTCTTCGCTAATAACACCAGCCTGGAGCGGCATATGAAGCGTCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCCCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGTGAAACGCCCTTCCGTTGCCAGTACTGCGCAAAGACGTTTACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGACGTCTGTGGCAAGAAATACACACGCAAGGAGCATCTAGCTAATCATATGCGCTCCCATACAAACGAGACACCGTTTCGCTGTGAAATTTGCGGCAAGAGCTTTAGCCGCAAGGAACATTTTACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGTTGCGATTTCTGCTCCAAGACGTTTACGCGCAAGGAACATCTGTTAAATCACGTGCGTCAGCACACGGGTGAATCGCCCCATCGCTGCTCCTACTGCATGAAGACCTTTACACGCAAGGAGCATCTGGTCAATCACATTCGTCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACAAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACCAAGACGTTCACACGCAAGGAGCATCTGACGAATCATGTGCGCCAGCATACTGGCGACTCACCGCATCGTTGCTCCTACTGCAAGAAGACATTCACACGCAAGGAGCATTTGACAAATCATGTCCGTTTGCATACGGGAGATTCGCCCCACAAGTGCGAATATTGCCAGAAGACATTCACACGAAAGGAGCATCTCAATAATCATATGCGTCAACATTCTAGCGATAATCCGCATTGCTGCAATGTCTGCAATAAGCCATTTACTCGCAAGGAGCATCTGATCAATCATATGTCACGTTGCCATACAGGCGATCGTCCTTTCACATGCGAAACATGCGGCAAATCGTTCCCACTCAAGGGCAATCTATTGTTCCATCAGCGTAGCCATACCAAGGGGCAGGAGATGGAGCGTCCGTTTTCATGCGAAAAGTGTCCCAAGAATTTCATATGCAAAGGTCACTTAGTCTCGCATATGCGATCCCATTCGGGTGAGAAACCACACGCGTGCACACTGTGCAGCAAGGCGTTCGTTGAGCGTGGCAATTTGAAGCGCCACATGAAGATGAATCATCCGGATGCCATGATGCCACCACCACCAGTGCATCCGCATCCGCAAATACCAGCCGGTGTGCTGACACAAGTCAAACAGGAAGTGAAACCGATTATAAGTGAGTCGGCATGCACTCAATTTTTGAGAGAATGCACAAAATTAGCCAACGCTCCAGAGCGTGATCTATCGTGA
Protein Sequence
MQHVSAASSVPSVIAPVVTTGGTTITLGGGPPPPSSSLAKSEIKEDGKPPHGMELYKVNIEDISQLFTYHEVFGKIHGDVVNHQLVAAAHGGQLPPPPPLPPQTHASSAAAAAAAAAATTNNAAVAAVMASANAAAAAAAAASAAGGVPSTTSSVGGGGIPGVVTTTTSSSTGSSGGASGAAGGGTTSSTTGELLMPKMEGGLHGNVDAGGGGQTQVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIISESACTQFLRECTKLANAPERDLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00604241;
80% Identity
-