Dacu016447.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila acutilabella
Gene Symbol
-
Assembly
GCA_035046005.1
Location
JAWNOK010000068.1:6038113-6045449[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.8e-05 0.0022 18.6 2.1 1 23 308 330 308 330 0.97
2 20 9.1e-06 0.00071 20.1 0.4 1 23 336 358 336 358 0.97
3 20 0.0013 0.1 13.3 0.9 1 23 364 386 364 386 0.95
4 20 1.9e-05 0.0015 19.1 3.1 1 23 392 414 392 414 0.97
5 20 4.4e-05 0.0034 18.0 4.7 1 23 420 442 420 442 0.99
6 20 8e-05 0.0063 17.1 5.7 1 23 448 470 448 470 0.97
7 20 3.9e-07 3.1e-05 24.4 4.3 1 23 476 498 476 498 0.98
8 20 1.4e-07 1.1e-05 25.8 2.4 1 23 504 526 504 526 0.97
9 20 1.4e-05 0.0011 19.5 4.5 1 23 533 555 533 555 0.97
10 20 0.00056 0.043 14.5 5.0 1 23 561 583 561 583 0.97
11 20 8.2e-05 0.0064 17.1 6.7 1 23 589 611 589 611 0.97
12 20 0.00014 0.011 16.4 6.5 1 23 617 639 617 639 0.98
13 20 1.3e-05 0.001 19.7 4.5 1 23 645 667 645 667 0.98
14 20 9.3e-06 0.00072 20.1 8.1 1 23 673 695 673 695 0.98
15 20 7.5e-06 0.00059 20.4 7.6 1 23 701 723 701 723 0.97
16 20 8.4e-07 6.6e-05 23.4 7.7 1 23 729 751 729 751 0.98
17 20 0.00026 0.021 15.5 9.5 1 23 757 780 757 780 0.95
18 20 9.4e-05 0.0073 16.9 0.9 1 23 786 808 786 808 0.98
19 20 0.001 0.08 13.7 3.4 1 23 818 840 818 840 0.97
20 20 1.2e-05 0.00091 19.8 1.6 1 23 846 869 846 869 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCATCCTCGGTGGTGACCACTGGCGGTGGCACCACCACCATAACATTGGGCGGTGGACCGCCCCCGATATCGttatcaaataaattgattgatCATCATAACagtcataatcatcatcatcaacagcagcaacaacaacagcaacaacagcagcagcagcaacaacaacagcagcaacaacatcatcataaTAGTAAAGAGGACGCTGCGAAGCAACAGCTTCAGCCGCCACACGGCTTGGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTCGGTAAAATCCATGGCGATGTGGTGAATCATGTGGCAGCGGTGCATGGCGGCAGTCAattgccaccgccaccgcaaTTGCCGCCGCCACCGCCGTTGCCACCGCAGACGACGCATTCATCGGCAagcgcagcagctgcagcagcagcggcggcgtCCACAAATAATGCAACCGTCGCTGCTGTAATGGCCTCGGccaatgcagcagcagcggctgcagcagccgcctcagcagcggcaacagcacaacaacaacagcaacaacaacaacagcaacaacaagcagtgACTAGCACAAATGCGGGAAGCCAGCAGGGCAGCGCCACGGTGACCACGACTAGCTCAGGTAGCAACGggaacaataataataataataacaataacagtaatgggggcagcaacaataataataataacagtaaTAATAGTAACAattcgacaacaacaaccacaacagcaacgggTGAATTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCATCGATGGTcagtcgtcgtcatcgtcgagCGTTACATTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGATATTTGTGggaaaatgtttcaatttcGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCATTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTAACACGTCATGGTAAAATCCATATTGGCGGTCCAATGTTCACCTGCATCGTTTGCTTCAATGTCTTTGCGAATAACACCAGTTTGGAGCGTCACATGAAACGGCATTCGACGGACAAACCATTTGCCTGCACCATTTGCCAAAAGACATTCGCACGCAAAGAGCATTTGGATAATCATTTTCGTTCGCATACTGGTGAAACGCCATTTCGTTGCCAATACTGCGCCAAGACGTTTACACGCAAGGAGCACATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCATTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGACAAACACCACATCAGTGTGATGTCTGTGGCAAGAAATACACACGCAAGGAGCATCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGCTGTGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGgagaatttattaaatcatgTGCGACAGCACACGGGAGAGTCACCGCATCGCTGCTCCTACTGCATAAAGACGTTCACACGCAAGGAGCATCTGGTGAATCATATACTCCAGCACACGGGCGAGACGCCACATCGGTGTGATTTCTGCTCCAAGACGTTCACACGCAAGGAACACTTGTTAAATCACGTGCGACAGCACACGGGAGAGTCACCGCATCGCTGTTCGTACTGCATGAAGACGTTTACACGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTCACACGCAAGGAGCATCTTACGAATCATGTGCGACAGCACACCGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACCTTCACCCGTAAGGAGCATCTGACGAATCATGTACGCCTGCACACTGGAGATTCGCCCCACAAATGCGAATACTGCCAGAAGACGTTCACACGCAAGGAGCATCTCAATAATCATATGCGCCAGCATTCAAGCGACAATCCCCATTGCTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCATTTGATCAATCACATGTCACGTTGCCACACCGGTGATCGTCCCTTCACCTGTGAGACTTGCGGCAAATCCTTCCCCCTCAAGGGCAATCTGCTTTTCCATCAGCGCAGCCATACCAAGGGACAGGAGTGTGAACGTCCCTTTGCCTGCGAAAAGTGTCCCAAGAATTTCATTTGCAAGGGTCACTTGGTCTCGCACATGCGATCCCATTCGGGCGAGAAACCGCACGCGTGCACGCTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCAGATGCAATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCACATCActcgacgacgacaacaatgCATACCATACAGCAGATAACCGCTGGTGCTGCAGCCGCTGGTGCTGGGGCCGTGCAGTTGACACCCGGACTGGTACCGCTCGTCTCGAGCACCCTCATCTCGTCGCACAATGCACAGCAATcgcagaagcaacagcaggcggcagcagcagcagtcgctgCCCAACAGCaagcggcagctgcagcagcggctcAACAACaggctgcagcagcagcggccgcccaacagcaggcagcagctgtggcacatcaacagcatcagcaacaggttgctgcacagcagcaacaacagcagcagcaggctgCTGTAGCAgcacatcagcagcagcaacaacagttgcaacagcaacagttgctacAGTTGTCCATGCAGGCAGCacatcatcaacatcagcagcagcaacaacagcagcagcaacaacatcatcaacagcagcaacaacaacaggctcATCCACAGGCAccgccacagcagcagcagcaacaacaacagccaccacCGCAGGTGCCAATTGCATTGATAAGTGATCCAAGCGCATTGGCACGAGCTGccatgcaactgcaacatctGCCCACCAATGTGGAGCAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPSSVVTTGGGTTTITLGGGPPPISLSNKLIDHHNSHNHHHQQQQQQQQQQQQQQQQQQQQHHHNSKEDAAKQQLQPPHGLEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGGSQLPPPPQLPPPPPLPPQTTHSSASAAAAAAAAASTNNATVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQQAVTSTNAGSQQGSATVTTTSSGSNGNNNNNNNNNSNGGSNNNNNNSNNSNNSTTTTTTATGELLMPKMEGGIHGIDGQSSSSSSVTLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKENLLNHVRQHTGESPHRCSYCIKTFTRKEHLVNHILQHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSTTTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVSSTLISSHNAQQSQKQQQAAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAVAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSMQAAHHQHQQQQQQQQQQHHQQQQQQQAHPQAPPQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00569113;
80% Identity
-