Basic Information

Insect: Drosophila demipolita
Gene Symbol: -
Assembly: GCA_035042405.1
Location: JAWNLI010000044.1:3173622-3180557[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.2e-05 0.0016 18.7 2.1 1 23 254 276 254 276 0.97

2 18 7.4e-06 0.00052 20.3 0.4 1 23 282 304 282 304 0.97

3 18 0.0011 0.076 13.4 0.9 1 23 310 332 310 332 0.95

4 18 1.6e-05 0.0011 19.2 3.1 1 23 338 360 338 360 0.97

5 18 3.6e-05 0.0025 18.1 4.7 1 23 366 388 366 388 0.99

6 18 6.5e-05 0.0046 17.3 5.7 1 23 394 416 394 416 0.97

7 18 3.2e-07 2.2e-05 24.6 4.3 1 23 422 444 422 444 0.98

8 18 1.1e-07 8e-06 26.0 2.4 1 23 450 472 450 472 0.97

9 18 6.7e-05 0.0047 17.3 6.7 1 23 479 501 479 501 0.97

10 18 0.00012 0.0081 16.5 6.5 1 23 507 529 507 529 0.98

11 18 1e-05 0.00072 19.8 4.5 1 23 535 557 535 557 0.98

12 18 7.5e-06 0.00053 20.2 8.1 1 23 563 585 563 585 0.98

13 18 6.1e-06 0.00043 20.5 7.6 1 23 591 613 591 613 0.97

14 18 6.8e-07 4.8e-05 23.5 7.7 1 23 619 641 619 641 0.98

15 18 0.00021 0.015 15.7 9.5 1 23 647 670 647 670 0.95

16 18 7.6e-05 0.0053 17.1 0.9 1 23 676 698 676 698 0.98

17 18 0.00083 0.058 13.8 3.4 1 23 708 730 708 730 0.97

18 18 9.4e-06 0.00066 19.9 1.6 1 23 736 759 736 759 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.2e-05	0.0016	18.7	2.1	1	23	254	276	254	276	0.97
2	18	7.4e-06	0.00052	20.3	0.4	1	23	282	304	282	304	0.97
3	18	0.0011	0.076	13.4	0.9	1	23	310	332	310	332	0.95
4	18	1.6e-05	0.0011	19.2	3.1	1	23	338	360	338	360	0.97
5	18	3.6e-05	0.0025	18.1	4.7	1	23	366	388	366	388	0.99
6	18	6.5e-05	0.0046	17.3	5.7	1	23	394	416	394	416	0.97
7	18	3.2e-07	2.2e-05	24.6	4.3	1	23	422	444	422	444	0.98
8	18	1.1e-07	8e-06	26.0	2.4	1	23	450	472	450	472	0.97
9	18	6.7e-05	0.0047	17.3	6.7	1	23	479	501	479	501	0.97
10	18	0.00012	0.0081	16.5	6.5	1	23	507	529	507	529	0.98
11	18	1e-05	0.00072	19.8	4.5	1	23	535	557	535	557	0.98
12	18	7.5e-06	0.00053	20.2	8.1	1	23	563	585	563	585	0.98
13	18	6.1e-06	0.00043	20.5	7.6	1	23	591	613	591	613	0.97
14	18	6.8e-07	4.8e-05	23.5	7.7	1	23	619	641	619	641	0.98
15	18	0.00021	0.015	15.7	9.5	1	23	647	670	647	670	0.95
16	18	7.6e-05	0.0053	17.1	0.9	1	23	676	698	676	698	0.98
17	18	0.00083	0.058	13.8	3.4	1	23	708	730	708	730	0.97
18	18	9.4e-06	0.00066	19.9	1.6	1	23	736	759	736	759	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGAGCCCCGTCATTGTCCGGTGTCAAATCGACGGAAGCATCACATAAAGAGGACAGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACTTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGGTGCATGGCAGTCAATTGCCACCGCCGCAACTGCCACCGCCGCCCCCCCTACCGCCACAGACGACGCATTCGGCAagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCAGCCGTTGCTGCTGTAATGGCCTCGGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGcatcagcagcggcatcagcacaacagcaacaacagcaacaacaacagcaacaacagcagcaacaacagcaacaacagcagcaacaacagcagcaacaacaacagccagcgACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACAACGACCAGCTCGGGCAGCAACGGGGGTGGGAATGGGGGCAACAACTCGACGACAACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGATATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCACAGCGAGCGTAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGCGGTCCCATGTTCACGTGCATTGTGTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCTTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgtCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCTTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCACTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCACCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCACACGGGCGATTCGCCGCACCGCTGCTCCTACTGCAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAATCATGTCCGCCTGCACACGGGGGACTCGCCGCACAAGTGCGAGTACTGTCAGAAGACGTTCACACGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGTTGCAACGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCCCGCTGCCACACCGGCGATCGTCCCTTTACCTGCGAGACGTGCGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTATCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCACAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcggcgacgacgacgatgcaCACCATACAACAGATAACAGCAGGCGCCGCAGCAGCGGGCGCCGGAGCCGTCCAGTTAGCGCCAGGCCTGGTGCCGCTGGTCACCAGCTCGCTCATCTCGCACAATGCGCAGCAGtcgcagaagcagcagcaggcggctgcagcagttgccgcccaacagcaggcggcagcagcagctgcggcacaGCAACAGGCGgccgctgcggcagctgctcagcagcaggcggcggcagcagcagcgcaccaacagcatcagcaacaggtggccgcacaacagcagcaacaacagcagcagcagcaggctgcCGTCGCtgcacatcagcagcagcaacagcagcttcagcagcaacagttgctccaATTGTCCATACAGCAGGCggcccatcatcatcagcagcaccagcaacagcagcagcaacaacagcagcagcagcagcaacatcatcaacagcagcaacagtcgcatcCGCAGGCAccgccgcaacagcagcagcagcagcaacagcagccgccgtCACAGGTGCCTATAGCATTGATAAGTGATCCAGGTGCGCTGGCACGTGCCGCcatgcagctgcaacatctGCCAACAAATGTGGAACAGCATCCAGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGAPSLSGVKSTEASHKEDSGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAASAQQQQQQQQQQQQQQQQQQQQQQQQQQQQPATSTNAGSQQGSATVTTTSSGSNGGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLAPGLVPLVTSSLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQQQQHHQQQQQSHPQAPPQQQQQQQQQPPSQVPIALISDPGALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: -