Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:10842097-10856459[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2e-05 0.0012 18.8 2.1 1 23 236 258 236 258 0.97

2 18 6.7e-06 0.00038 20.3 0.4 1 23 264 286 264 286 0.97

3 18 0.00099 0.056 13.5 0.9 1 23 292 314 292 314 0.95

4 18 1.4e-05 0.00081 19.3 3.1 1 23 320 342 320 342 0.97

5 18 3.2e-05 0.0018 18.1 4.7 1 23 348 370 348 370 0.99

6 18 5.9e-05 0.0034 17.3 5.7 1 23 376 398 376 398 0.97

7 18 2.9e-07 1.6e-05 24.6 4.3 1 23 404 426 404 426 0.98

8 18 1e-07 5.9e-06 26.0 2.4 1 23 432 454 432 454 0.97

9 18 6e-05 0.0034 17.3 6.7 1 23 461 483 461 483 0.97

10 18 0.0001 0.006 16.5 6.5 1 23 489 511 489 511 0.98

11 18 9.4e-06 0.00053 19.8 4.5 1 23 517 539 517 539 0.98

12 18 6.8e-06 0.00039 20.3 8.1 1 23 545 567 545 567 0.98

13 18 5.5e-06 0.00032 20.6 7.6 1 23 573 595 573 595 0.97

14 18 6.2e-07 3.5e-05 23.5 7.7 1 23 601 623 601 623 0.98

15 18 0.00019 0.011 15.7 9.5 1 23 629 652 629 652 0.95

16 18 6.9e-05 0.0039 17.1 0.9 1 23 658 680 658 680 0.98

17 18 0.00075 0.043 13.8 3.4 1 23 690 712 690 712 0.97

18 18 8.5e-06 0.00049 20.0 1.6 1 23 718 741 718 741 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2e-05	0.0012	18.8	2.1	1	23	236	258	236	258	0.97
2	18	6.7e-06	0.00038	20.3	0.4	1	23	264	286	264	286	0.97
3	18	0.00099	0.056	13.5	0.9	1	23	292	314	292	314	0.95
4	18	1.4e-05	0.00081	19.3	3.1	1	23	320	342	320	342	0.97
5	18	3.2e-05	0.0018	18.1	4.7	1	23	348	370	348	370	0.99
6	18	5.9e-05	0.0034	17.3	5.7	1	23	376	398	376	398	0.97
7	18	2.9e-07	1.6e-05	24.6	4.3	1	23	404	426	404	426	0.98
8	18	1e-07	5.9e-06	26.0	2.4	1	23	432	454	432	454	0.97
9	18	6e-05	0.0034	17.3	6.7	1	23	461	483	461	483	0.97
10	18	0.0001	0.006	16.5	6.5	1	23	489	511	489	511	0.98
11	18	9.4e-06	0.00053	19.8	4.5	1	23	517	539	517	539	0.98
12	18	6.8e-06	0.00039	20.3	8.1	1	23	545	567	545	567	0.98
13	18	5.5e-06	0.00032	20.6	7.6	1	23	573	595	573	595	0.97
14	18	6.2e-07	3.5e-05	23.5	7.7	1	23	601	623	601	623	0.98
15	18	0.00019	0.011	15.7	9.5	1	23	629	652	629	652	0.95
16	18	6.9e-05	0.0039	17.1	0.9	1	23	658	680	658	680	0.98
17	18	0.00075	0.043	13.8	3.4	1	23	690	712	690	712	0.97
18	18	8.5e-06	0.00049	20.0	1.6	1	23	718	741	718	741	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGCCATTGCCCGGCAACAAGTCAGATCATAAAGAGGACGGCAGCAAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAGTTATTTACATACCACGAGGTATTTGGAAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGCGCATGGCAGTCAGTTGCCACCGCCGCAATTGCCACCGCCTCCGCCATTACCGCCACAGACGACGCATTCGGCtagcgcagctgcagctgcagcggcggtGTCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCATCAGCCAATGCAGCAGCCGCGGCTGCAGCGGCCGCATCGGCTGCGGCCACggcccaacagcaacagcagcagcaacagcaacagcaagcccCAGCGACAAGCACAAATGCTGGAACACAGCAAGGCAGCGCCACGGTGACCACAACTAGCTCCTCCGGCAGCAACGGGGGGAATGGGGGAAACAACAAtgcgacaacgacgacgacgggtGAGTTGCTAATGCCGAAAATGGAGGGCGGCATCCATGGCGTTGATGGGCAATCGAGCGTTGCGTTGGCGCCAGATGGCACGCCCATAGCAACTGGGACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAATTTCGCTATCAGCTAATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCAGGCATGGCAAGATCCATATTGGCGGTCCCATGTTCACTTGCATTGTCTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCACATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCACCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACGCGCAAGGAGCATTTGACGAATCATGTCCGCCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACGTTTACCCGCAAGGAGCATTTGACGAATCATGTGCGCCTGCACACTGGAGATTCGCCGCACAAATGCGAATACTGCCAGAAGACGTTCACGCGCAAGGAGCATCTCAATAATCACATGCGCCAGCACTCCAGCGACAATCCCCATTGCTGCAATGTGTGCAACAAGCCCTTCACACGCAAGGAGCACTTGATCAATCATATGTCTCGCTGTCACACCGGCGATCGTCCCTTCACCTGTGAGACGTGCGGCAAGTCGTTCCCCCTCAAGGGCAATCTCCTGTTCCATCAGCGCAGCCACACCAAGGGCCAGGAATGCGAGCGTCCATTTGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCATTCGGCGACGACCACCATGCACACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCCGGCGCTGGTGCCGTCCAGCTGACGCCCGGTCTGGTGCCGCTCGTCACCAGCACGCTCATCTCCCATAATGCCCAGCAGtcgcagaagcaacagcagcaggttgctgctgcagtagctgcccagcagcaggcggcagcagcagccgccgcccaacagcaagcagcagcagcggctcaGCAGcaagcggcggcggcagcagcgcaccagcagcatcagcaacaggtggccgcacagcaacaacaacaacagcagcaggcagcagttgctgcacatcaacagcagcaacagcaactgcagcagcagcagttgttgcaattgtcCATACAGCAGGCGgcgcatcatcatcagcaacagcagcagcagcatcaacagcagcaacaacagcagcaacaacaacaacagcagcagcatcatccaCAGCAACAGTCGCATCCGCAGGCgccgccacagcagcagcagcaacagccaccgcCACAGGTGCCCATTGCATTGATAAGTGATCCAAGCGCGCTGGCCCGTGCCGCTATGCAGTTGCAGCATCTGCCCACAAATGTGGAGCAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPGNKSDHKEDGSKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAAHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAVSTNNAAVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQAPATSTNAGTQQGSATVTTTSSSGSNGGNGGNNNATTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISHNAQQSQKQQQQVAAAVAAQQQAAAAAAAQQQAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQQQQQHQQQQQQQQQQQQQQHHPQQQSHPQAPPQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00479608;
80% Identity: -