Dniv003554.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila niveifrons
Gene Symbol
-
Assembly
GCA_035046325.1
Location
JAWNOC010000045.1:265027-273481[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 2.7e-05 0.0017 18.6 2.1 1 23 303 325 303 325 0.97
2 20 8.8e-06 0.00057 20.1 0.4 1 23 331 353 331 353 0.97
3 20 0.0013 0.084 13.3 0.9 1 23 359 381 359 381 0.95
4 20 1.9e-05 0.0012 19.1 3.1 1 23 387 409 387 409 0.97
5 20 4.3e-05 0.0028 18.0 4.7 1 23 415 437 415 437 0.99
6 20 7.8e-05 0.005 17.1 5.7 1 23 443 465 443 465 0.97
7 20 3.8e-07 2.5e-05 24.4 4.3 1 23 471 493 471 493 0.98
8 20 1.4e-07 8.8e-06 25.8 2.4 1 23 499 521 499 521 0.97
9 20 6.6e-06 0.00043 20.5 4.1 1 23 528 550 528 550 0.97
10 20 5.7e-06 0.00037 20.7 6.7 1 23 556 578 556 578 0.98
11 20 8e-05 0.0052 17.1 6.7 1 23 584 606 584 606 0.97
12 20 0.00014 0.009 16.4 6.5 1 23 612 634 612 634 0.98
13 20 1.2e-05 0.0008 19.7 4.5 1 23 640 662 640 662 0.98
14 20 9e-06 0.00058 20.1 8.1 1 23 668 690 668 690 0.98
15 20 7.3e-06 0.00047 20.4 7.6 1 23 696 718 696 718 0.97
16 20 8.2e-07 5.3e-05 23.4 7.7 1 23 724 746 724 746 0.98
17 20 0.00026 0.017 15.5 9.5 1 23 752 775 752 775 0.95
18 20 9e-05 0.0059 16.9 0.9 1 23 781 803 781 803 0.98
19 20 0.00099 0.064 13.7 3.4 1 23 813 835 813 835 0.97
20 20 1.1e-05 0.00073 19.8 1.6 1 23 841 864 841 864 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACTTTGGGCCACAAAGCCAGCgatccacagcagcagcagcatcaacagcaacatcatcatcttgCTCAtcttcagcagcaacatcagcagcttcaacagcagcaccatcagaataataacaataataacagtaaAGTGGACGGAGGGAATAAGCAACAACCGACAACAGCACACGGCGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAATTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCGGCGGTGCATGGCAGTCAGTTGCCACCGCCACAACTGCCACCGCCTCCGCCACTGCCAccgcaagcaacagcagcatccacGACGCATGCATCGGCTagcgcagctgcagccgcagcgGCGGTGTCCACAAATAATGCAACTGTCGCTGCTGTAATGGCCTCGGCCaatgcagcagccgcagctgcagctgccgcatcagcggcagcaacagcacaacaacaacagcagcaacagcaacaacaacagcagcagcagcaacaacagcagcaacagcaacaagctgTGACTAGCACAAATGCTGGGACACAGCAGGGCAGTGCCACGGTGACGACAACTAGCTCaggtagcaacaacagcgggaATAACAGTGGgggcaataataataacactagtaacagtaacagtaacaacaacaataacagttcgacgacaacgacaacaaccgGTGAACTGCTGATGCCGAAAATGGAGGGTGGCATCCATGGCGTCGATGGTCAATCGAGCGTTGCCTTGGCCCCCGATGGCACACCGATTGCGACTGGGACGCATGTGTGCGATATTTGTgggaaaatgtttcaatttcgTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGCAAGCCATTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGTAAAATTCATATTGGCGGTCCCATGTTCACGTGCATTGTGTGCTTCAATGTGTTTGCCAACAATACCAGTTTGGAGCGTCACATGAAACGTCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCGCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTCAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACACGCAAGGAGAATTTGATAAATCACGTGCGCCAGCACACGGGAGAATCGCCGCATCGCTGCTCCTACTGCAGCAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGGAAGGAGCATCTGGTGAATCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACGAAGACCTTCACAAGGAAGGAGCACCTAACGAATCATGTGCGCCAGCACACGGGCGATTCGCCGCATCGCTGCTCCTACTGCAAGAAGACCTTCACCCGGAAGGAGCATCTGACGAATCACGTTCGCCTGCACACTGGAGATTCGCCCCACAAATGCGAATACTGTCAGAAGACCTTCACCCGGAAGGAGCATCTCAATAACCATATGCGTCAGCATTCGAGCGACAATCCCCATTGCTGCAATGTGTGCAACAAGCCGTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGTTGCCACACCGGCGATCGTCCCTTCACATGCGAGACATGCGGCAAATCGTTCCCCCTCAAGGGCAATCTGCTGTTCCATCAGCGTAGCCACACCAAGGGTCAGGAGTGCGAACGTCCGTTTGCCTGCGAGAAATGTCCcaagaatttcatttgcaaagGTCACCTGGTGTCGCACATGCGCTCCCATTCTGGAGAGAAACCGCATGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGGGGCAATTTGAAGCGGCACATGAAGATGAATCACCCGGATGCCATGATGCCGCCCCCGCCCGTGCATCCGCATCCACAGATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCGCATCATTCGGCGACGACCACAATGCATACCATACAGCAGATAACAGCGGGCGCTGCAGCGGCTGGCGCCGGTGCCGTCCAGCTAACGCCAGGCCTGGTGCCGTTGGTCACCAGTACGCTCATCTCCTCGCACAACGCTCAGCAGacgcagaagcaacagcaggcagcagccgccgttgctgcacagcaacaagcagcggctgctgctgctgcggcacaacagcaacaggcagcggctgcagctgcagctcagcagcaggcggcagcGGTGGcccatcagcagcatcagcaacaggttgccgcccagcagcagcaacaacagcaacaggctgCGGTGGCagcacatcagcagcagcaacagcagttgcagcagcagcaattgttgcagttgtccATACAGCAGGCGGCGcatcatcaccagcagcatcagcagcagcagcagcaacaacagcagcagcagcaacaccatcagcagcaacaggcacaTCCGCAGGcaccgccacagcagcagcaacagcagccgccacCGCAGGTGCCCATCGCCTTAATTAGCGATCCAAGCGCCTTGGCACGCGCTGcgatgcagctgcaacatctGCCCACGAATGTGGAGCAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGHKASDPQQQQHQQQHHHLAHLQQQHQQLQQQHHQNNNNNNSKVDGGNKQQPTTAHGGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQATAASTTHASASAAAAAAAVSTNNATVAAVMASANAAAAAAAAASAAATAQQQQQQQQQQQQQQQQQQQQQQAVTSTNAGTQQGSATVTTTSSGSNNSGNNSGGNNNNTSNSNSNNNNNSSTTTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKENLINHVRQHTGESPHRCSYCSKTFTRKEHLVNHIRQHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSTLISSHNAQQTQKQQQAAAAVAAQQQAAAAAAAAQQQQAAAAAAAQQQAAAVAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQQQHHQQQQAHPQAPPQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00509230;
80% Identity
-