Basic Information

Insect: Drosophila cognata
Gene Symbol: -
Assembly: GCA_035041535.1
Location: JAWNLC010000590.1:964084-971021[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.6e-05 0.0016 18.7 2.1 1 23 253 275 253 275 0.97

2 18 8.5e-06 0.00054 20.3 0.4 1 23 281 303 281 303 0.97

3 18 0.0012 0.079 13.4 0.9 1 23 309 331 309 331 0.95

4 18 1.8e-05 0.0011 19.2 3.1 1 23 337 359 337 359 0.97

5 18 4.1e-05 0.0026 18.1 4.7 1 23 365 387 365 387 0.99

6 18 7.4e-05 0.0047 17.3 5.7 1 23 393 415 393 415 0.97

7 18 3.6e-07 2.3e-05 24.6 4.3 1 23 421 443 421 443 0.98

8 18 1.3e-07 8.3e-06 26.0 2.4 1 23 449 471 449 471 0.97

9 18 7.6e-05 0.0049 17.3 6.7 1 23 478 500 478 500 0.97

10 18 0.00013 0.0084 16.5 6.5 1 23 506 528 506 528 0.98

11 18 1.2e-05 0.00075 19.8 4.5 1 23 534 556 534 556 0.98

12 18 8.6e-06 0.00055 20.2 8.1 1 23 562 584 562 584 0.98

13 18 7e-06 0.00044 20.5 7.6 1 23 590 612 590 612 0.97

14 18 7.8e-07 5e-05 23.5 7.7 1 23 618 640 618 640 0.98

15 18 0.00024 0.016 15.7 9.5 1 23 646 669 646 669 0.95

16 18 8.7e-05 0.0055 17.1 0.9 1 23 675 697 675 697 0.98

17 18 0.00095 0.06 13.8 3.4 1 23 707 729 707 729 0.97

18 18 1.1e-05 0.00069 19.9 1.6 1 23 735 758 735 758 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.6e-05	0.0016	18.7	2.1	1	23	253	275	253	275	0.97
2	18	8.5e-06	0.00054	20.3	0.4	1	23	281	303	281	303	0.97
3	18	0.0012	0.079	13.4	0.9	1	23	309	331	309	331	0.95
4	18	1.8e-05	0.0011	19.2	3.1	1	23	337	359	337	359	0.97
5	18	4.1e-05	0.0026	18.1	4.7	1	23	365	387	365	387	0.99
6	18	7.4e-05	0.0047	17.3	5.7	1	23	393	415	393	415	0.97
7	18	3.6e-07	2.3e-05	24.6	4.3	1	23	421	443	421	443	0.98
8	18	1.3e-07	8.3e-06	26.0	2.4	1	23	449	471	449	471	0.97
9	18	7.6e-05	0.0049	17.3	6.7	1	23	478	500	478	500	0.97
10	18	0.00013	0.0084	16.5	6.5	1	23	506	528	506	528	0.98
11	18	1.2e-05	0.00075	19.8	4.5	1	23	534	556	534	556	0.98
12	18	8.6e-06	0.00055	20.2	8.1	1	23	562	584	562	584	0.98
13	18	7e-06	0.00044	20.5	7.6	1	23	590	612	590	612	0.97
14	18	7.8e-07	5e-05	23.5	7.7	1	23	618	640	618	640	0.98
15	18	0.00024	0.016	15.7	9.5	1	23	646	669	646	669	0.95
16	18	8.7e-05	0.0055	17.1	0.9	1	23	675	697	675	697	0.98
17	18	0.00095	0.06	13.8	3.4	1	23	707	729	707	729	0.97
18	18	1.1e-05	0.00069	19.9	1.6	1	23	735	758	735	758	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGTCATTGTCCGGTGTCAAATCGGCGGAATCTTCGCATAAAGAGGACGGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGGTTCATGGCAGCCAATTGCCACCGCCGCAACTGCCACCGCCGCCCCCCTTACCGCCACAGACGACGCATTCGGCaagcgcagctgcagcagcagcggcggcgtcCACAAATAATGCAGCGGTTGCTGCTGTAATGGCCTCGgccaatgcagcagcagcggctgcagcagccgcatcagcagcggcatcagcacaacagcaacaacagcaacaacaacagcaacaacagcaacaacaacagcaacaacagcagcaacaacagcaacaacaacagccagcgACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACAACGACCAGCTCGGGAAGCAACGGGGGTGGGAACGGGGGCAACAACTCAACGACAACGACGGGTGAGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCATAGCGAGCGCAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGCGGTCCCATGTTCACGTGCATTGTATGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGgtCAAACACCGCATCAATGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCATGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACTCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCATACGGGCGATTCGCCGCACCGCTGCTCCTACTGCAAGAAGACCTTCACCCGCAAGGAGCACCTGACGAATCATGTGCGCCTGCACACGGGGGACTCGCCGCACAAGTGCGAATACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGTTGCAACGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACTTGCGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAAGAGTGCGAGCGTCCATTTGCCTGCGAGAAGTGCCCcaagaatttcatttgcaaagGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCActcggcgacgacgacgatgcaCACCATACAGCAGATAACAGCAGGCGCCGCAGCGGCGGGTGCCGGGGCCGTCCAGTTAGCGCCGGGCCTGGTGCCGCTGGTCACCAGCTCGCTCATCTCGCACAATGCGCAGCAGtcgcagaagcagcagcaggcggcggcagcagttgCCGCCCAACAGcaggctgcagcagcagccgctgcacaGCAACAGGCGGCCGCTGCGGCGGCAGCccagcagcaggcggcggcggcagcagcgcaccagcagcatcagcaacaggtggccgcacaacagcagcaacagcagcagcagcagcaggctgcCGTCGCtgcacatcagcagcagcaacagcaactgcagcagcaacagttgctccaATTGTCCATACAGCAGGCGGCCcaccatcatcagcagcatcagcagcagcagcaacagcagcagcagcagcatcatcaacagcagcaacagtcgcatcCGCAGGCaccgccacagcagcaacagcagcagcagcaacagcagccgccgccacAGGTGCCGATCGCATTGATAAGTGATCCGAGTGCGCTGGCACGTGCCGccatgcagctgcagcatctgcCCACAAATGTGGAACAGCATCCGGTGGTTTACTAA
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPSLSGVKSAESSHKEDGGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAASAQQQQQQQQQQQQQQQQQQQQQQQQQQQPATSTNAGSQQGSATVTTTSSGSNGGGNGGNNSTTTTGELLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLAPGLVPLVTSSLISHNAQQSQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAAAAHQQHQQQVAAQQQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQQHHQQQQQSHPQAPPQQQQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00560429;
80% Identity: iTF_00619994;