Dlim017863.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila limbata
Gene Symbol
-
Assembly
GCA_963924055.1
Location
OZ001353.1:25296305-25304171[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 2.8e-05 0.0029 18.6 2.1 1 23 254 276 254 276 0.97
2 22 9.3e-06 0.00094 20.1 0.4 1 23 282 304 282 304 0.97
3 22 0.0014 0.14 13.3 0.9 1 23 310 332 310 332 0.95
4 22 2e-05 0.002 19.1 3.1 1 23 338 360 338 360 0.97
5 22 4.5e-05 0.0045 18.0 4.7 1 23 366 388 366 388 0.99
6 22 8.2e-05 0.0083 17.1 5.7 1 23 394 416 394 416 0.97
7 22 4e-07 4.1e-05 24.4 4.3 1 23 422 444 422 444 0.98
8 22 1.4e-07 1.5e-05 25.8 2.4 1 23 450 472 450 472 0.97
9 22 6.5e-06 0.00066 20.6 5.5 1 23 478 500 478 500 0.97
10 22 2.5e-06 0.00025 21.9 6.4 1 23 506 528 506 528 0.98
11 22 1.1e-05 0.0011 19.9 3.3 1 23 534 556 534 556 0.98
12 22 3.5e-06 0.00035 21.5 6.4 1 23 562 584 562 584 0.98
13 22 8.4e-05 0.0085 17.1 6.7 1 23 590 612 590 612 0.97
14 22 0.00015 0.015 16.4 6.5 1 23 618 640 618 640 0.98
15 22 1.3e-05 0.0013 19.7 4.5 1 23 646 668 646 668 0.98
16 22 9.4e-06 0.00095 20.1 8.1 1 23 674 696 674 696 0.98
17 22 7.7e-06 0.00078 20.4 7.6 1 23 702 724 702 724 0.97
18 22 8.6e-07 8.7e-05 23.4 7.7 1 23 730 752 730 752 0.98
19 22 0.00027 0.027 15.5 9.5 1 23 758 781 758 781 0.95
20 22 9.5e-05 0.0096 16.9 0.9 1 23 787 809 787 809 0.98
21 22 0.001 0.11 13.7 3.4 1 23 819 841 819 841 0.97
22 22 1.2e-05 0.0012 19.8 1.6 1 23 847 870 847 870 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCGGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACGTTAGGCGGACCGCCGCCATTACCACATAAAGTCGATCATAAAGAGGACGGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCGCAACTATTTACGTATCACGAGGTCTTTGGCAAAATCCATGGCGATGTGGTGAATCATGTGGCCGCGGTGCATGGCAGTCAGTTGCCACCGCCACAActgccaccgccaccaccactGCCACCGCAGACGACGCATTCGGCAAgcgcagctgcagcagcagcggcggcgtCCACAAATAATGCAGCCGTCGCTGCTGTAATGGCCTCGGccaatgcagcagcagcggctgcagCAGCCGCATCAGCAGCGGCATCAgctcaacagcagcaacaacaacagcaacaacaacagcagcaacaacagcaacagcaagcaCAGCAATCAGTGACAAGCACAAATGCTGGAAGCCAGCAGGGCAGCGCCACGGTGACCACGACTAGCTCAGGTAGCAACGGGAACAATAATAATGGGGGTAATAATGggggaaacaacaacaataataacaataattcgACAACGACGACGGGTGAGTTGCTAATGCCTAAAATGGAGGGCGGCATTCATGGCGTCGATGGTCAGTCGAGCGTTTCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTTTGCGATATTTGTGGCAAGATGTTCCAATTTCGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGTAAGCCGTTTATGTGTCAGGTGTGCGGTCAGGGCTTTACCACATCGCAGGATTTGACCCGTCATGGCAAAATCCATATTGGCGGTCCCATGTTCACCTGCATTGTTTGCTTCAATGTGTTTGCCAATAATACAAGTTTGGAGCGACATATGAAAAGGCATTCAACGGACAAACCCTTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCATCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTCAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGGCGAGACGCCGCATCGGTGCGACATCTGCTCCAAGACGTTCACTCGCAAGGATCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAAACGCCGCATCGCTGCACCTACTGCCCGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATACACGCATGCACACGGGTGAGACACCGTTCCAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTATTCATGTACGGCAACATACAGGTGAAACGCCGCACAAGTGTACATACTGTGAGAAGACGTTTAACCGTAAGGAGCATCTAACGATTCATATACGCCAGCACACGGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTCACTCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCAcaagtgtacatactgcacgAAGACGTTTACCCGTAAGGAGCATCTAACGAATCATGTGCGCCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTACTGCAAGAAGACGTTCACCCGGAAGGAGCATCTGACGAATCATGTCCGACTTCACACTGGAGATTCGCCCCATAAATGCGAATATTGCCAGAAGACCTTCACACGCAAGGAGCATCTCAATAATCATATGCGTCAGCATTCTAGCGACAATCCCCATTGTTGCAACGTTTGCAACAAGCCCTTCACCCGCAAGGAGCATCTGATCAATCATATGTCACGCTGCCACACCGGCGATCGCCCCTTCACCTGCGAGACGTGCGGCAAATCTTTTCCCCTCAAGGGCAATCTACTTTTCCATCAACGCAGTCATACCAAGGGCCAGGAGTGCGAACGTCCGTTTGCCTGCGAAAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCTGGCGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGGGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCgtgcatccgcatccgcaaaTACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACAACAATGCACACCATACAACAGATAACAGCTGGAGCTGCTGCAGCTGGCGCCGGTGCCGTCCAGTTAACGCCAGGCTTGGTGCCGCTGGTCACCAGCTCGCTCATCTCGCACAATgcgcagcaaaagcaacaacaggcggcagcagcagttgctgcTCAACAGCAGGCGGCTGCAGCAGCCGCTGCACAGCAAcaggcggcagcagcagcggccgcACAACAGCAGGCAGCGGCAGTGGCacatcagcagcatcagcaacaggttgctgcacaacagcaacaacagcaacagcaggcgGCGGTGGCAgcacatcagcagcagcaacaacagttgcagcagcaacaattgctgcaATTATCGATACAGCAGGCGgcgcatcatcatcagcagcatcagcagcagcaacaacaacagcagcaacaccatcagcagcaacagcaacaggccCATCCGCAGGCGccgccacagcagcaacaacagcaacagccaccGCCACAGGTGCCCATTGCCTTGATAAGTGATCCAAGTGCATTGGCACGGGCTGCCATGCAACTGCAGCATCTGCCCAGCAATGTTGAGCAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPPLPHKVDHKEDGGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAAVHGSQLPPPQLPPPPPLPPQTTHSASAAAAAAAASTNNAAVAAVMASANAAAAAAAAASAAASAQQQQQQQQQQQQQQQQQQAQQSVTSTNAGSQQGSATVTTTSSGSNGNNNNGGNNGGNNNNNNNNSTTTTGELLMPKMEGGIHGVDGQSSVSLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDICSKTFTRKDHLLNHVRQHTGETPHRCTYCPKTFTRKEHLVNHTRMHTGETPFQCTYCTKAFTRKDHMVIHVRQHTGETPHKCTYCEKTFNRKEHLTIHIRQHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGAGAVQLTPGLVPLVTSSLISHNAQQKQQQAAAAVAAQQQAAAAAAAQQQAAAAAAAQQQAAAVAHQQHQQQVAAQQQQQQQQAAVAAHQQQQQQLQQQQLLQLSIQQAAHHHQQHQQQQQQQQQHHQQQQQQAHPQAPPQQQQQQQPPPQVPIALISDPSALARAAMQLQHLPSNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00601961;
80% Identity
-