Dwil004205.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila willistoni
Gene Symbol
-
Assembly
GCA_018902025.1
Location
JAFEWB010000714.1:12661646-12669342[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.7e-05 0.0014 19.1 2.1 1 23 230 252 230 252 0.97
2 18 5.7e-06 0.00047 20.6 0.4 1 23 258 280 258 280 0.97
3 18 0.00085 0.069 13.8 0.9 1 23 286 308 286 308 0.95
4 18 1.2e-05 0.00099 19.6 3.1 1 23 314 336 314 336 0.97
5 18 2.8e-05 0.0023 18.4 4.7 1 23 342 364 342 364 0.99
6 18 5e-05 0.0041 17.6 5.7 1 23 370 392 370 392 0.97
7 18 2.5e-07 2e-05 24.9 4.3 1 23 398 420 398 420 0.98
8 18 8.9e-08 7.2e-06 26.3 2.4 1 23 426 448 426 448 0.97
9 18 5.2e-05 0.0042 17.6 6.7 1 23 455 477 455 477 0.97
10 18 9e-05 0.0074 16.8 6.5 1 23 483 505 483 505 0.98
11 18 8e-06 0.00066 20.1 4.5 1 23 511 533 511 533 0.98
12 18 5.8e-06 0.00048 20.6 8.1 1 23 539 561 539 561 0.98
13 18 4.7e-06 0.00039 20.9 7.6 1 23 567 589 567 589 0.97
14 18 5.3e-07 4.3e-05 23.8 7.7 1 23 595 617 595 617 0.98
15 18 0.00017 0.014 16.0 9.5 1 23 623 646 623 646 0.95
16 18 5.9e-05 0.0048 17.4 0.9 1 23 652 674 652 674 0.98
17 18 0.00062 0.051 14.2 4.4 1 23 684 706 684 706 0.98
18 18 7.3e-06 0.0006 20.3 1.6 1 23 712 735 712 735 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTAAGCGCTGCCAGTTCGGTACCATCGGTAATTGCACCGGTGGTTACCACTGGAGGCACCACCATTACCTTAGGCGGTGGTCCACCACCGCCATCCTCATCCTTGGCCAAATCCGAGATTAAAGAAGATGGCAAACCGCCGCATGGCATGGAATTGTATAAAGTGAACATTGAGGATATTTCACAATTGTTTACATATCATGAAGTCTTTGGCAAAATACATGGAGATGTTGTCAATCATCAATTGGTGGCAGCGGCTCATGGTGGACAATTGCCACCGCCTCCACCGTTGCCGCCACAAACGCATGCCTCCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTCATCCACCGGAAGCAGTGGCGGCGCTAGTGGTGCCGCCGGCGCGGGTACCACATCGAGCACAACGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCCTACATGGCAACGTGGACGCTGGTGGCAACGGTCAAACCCAGGTGGCCTTAGCCCCTGATGGCACCCCAATTGCTACGGGGACGCATGTCTGCGATATATGTGGCAAGATGTTCCAGTTTCGGTATCAGCTAATTGTCCATCGTCGCTATCATAGCGAACGGAAACCGTTTATGTGTCAGGTATGCGGTCAGGGTTTTACCACATCGCAGGATCTGACACGACATGGTAAAATCCATATTGGCGGACCGATGTTCACCTGCATCGTTTGCTTCAATGTCTTCGCTAATAACACCAGCCTGGAGCGGCATATGAAGCGTCATTCAACGGACAAACCATTCGCCTGCACCATTTGCCAAAAGACATTTGCCCGCAAAGAGCATCTGGACAATCATTTTCGTTCGCACACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCAAAGACGTTTACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACGCCGCATCAGTGTGATGTCTGTGGCAAGAAATATACACGCAAGGAGCATCTAGCTAATCATATGCGCTCCCATACAAACGAGACACCGTTTCGCTGTGAAATTTGCGGCAAGAGCTTTAGCCGCAAGGAACACTTTACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGTTGCGATTTCTGCTCCAAGACGTTTACGCGCAAGGAACATCTGTTAAATCACGTGCGTCAGCACACGGGTGAATCGCCCCATCGCTGCTCCTACTGCATGAAGACCTTCACACGCAAGGAGCATCTGGTCAATCACATTCGTCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACAAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACCTATTGCACCAAGACGTTCACACGCAAGGAGCATCTGACGAATCATGTGCGCCAGCATACTGGCGACTCACCGCATCGTTGCTCCTACTGCAAGAAGACATTCACACGCAAGGAGCATTTGACAAATCATGTGCGTTTGCATACGGGAGATTCGCCGCACAAGTGCGAATATTGCCAGAAGACATTCACAAGAAAGGAGCATCTCAATAATCATATGCGTCAACACTCTAGCGATAATCCGCATTGTTGCAATGTCTGCAATAAGCCATTTACTCGCAAGGAGCATCTGATCAATCATATGTCACGTTGCCATACAGGCGATCGTCCTTTCACATGCGAAACATGCGGCAAATCGTTTCCACTCAAGGGCAATCTATTGTTCCATCAGCGTAGCCATACCAAGGGCCAGGAAATGGAACGTCCGTTCTCATGCGAAAAGTGCCCCAAAAACTTTATATGCAAAGGTCACTTGGTCTCGCATATGCGATCCCATTCGGGCGAGAAACCGCATGCGTGCACACTGTGCAGCAAGGCGTTCGTTGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAACCATCCGGATGCCATGATGCCGCCACCACCAGTGCATCCGCATCCGCAAATACCAGCCGGTGTGCTGACACAAGTCAAGCAGGAAGTGAAACCGATTATAATTCCCCACCATTCGGCGACAACGATGCACACCATACAACAGATAACATCGGGAGGAGCAGCCGGTGCCGGTGGAGCCCAACTGACGCCGGCTATGCAATTGCAACATTTGCCGGCCAATGTGGAACAACATCCGGTGGTTTACTAA
Protein Sequence
MQHVSAASSVPSVIAPVVTTGGTTITLGGGPPPPSSSLAKSEIKEDGKPPHGMELYKVNIEDISQLFTYHEVFGKIHGDVVNHQLVAAAHGGQLPPPPPLPPQTHASXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSTGSSGGASGAAGAGTTSSTTGELLMPKMEGGLHGNVDAGGNGQTQVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTMHTIQQITSGGAAGAGGAQLTPAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00560429;
90% Identity
iTF_00503405;
80% Identity
-