Basic Information

Insect: Scaptodrosophila lebanonensis
Gene Symbol: -
Assembly: GCA_003285725.2
Location: NW:1290721-1304806[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.2e-05 0.0014 18.6 2.1 1 23 367 389 367 389 0.97

2 18 7.2e-06 0.00045 20.1 0.4 1 23 395 417 395 417 0.97

3 18 0.0011 0.066 13.3 0.9 1 23 423 445 423 445 0.95

4 18 4.6e-06 0.00028 20.7 2.7 1 23 451 473 451 473 0.97

5 18 3.5e-05 0.0022 18.0 4.7 1 23 479 501 479 501 0.99

6 18 6.3e-05 0.0039 17.1 5.7 1 23 507 529 507 529 0.97

7 18 3.1e-07 1.9e-05 24.4 4.3 1 23 535 557 535 557 0.98

8 18 1.1e-07 6.9e-06 25.8 2.4 1 23 563 585 563 585 0.97

9 18 6.5e-05 0.004 17.1 6.7 1 23 592 614 592 614 0.97

10 18 0.00011 0.007 16.4 6.5 1 23 620 642 620 642 0.98

11 18 1e-05 0.00063 19.7 4.5 1 23 648 670 648 670 0.98

12 18 7.7e-06 0.00048 20.0 7.9 1 23 676 698 676 698 0.98

13 18 5.7e-06 0.00035 20.4 7.8 1 23 704 726 704 726 0.97

14 18 6.7e-07 4.1e-05 23.4 7.7 1 23 732 754 732 754 0.98

15 18 0.00021 0.013 15.5 9.5 1 23 760 783 760 783 0.95

16 18 7.4e-05 0.0046 16.9 0.9 1 23 789 811 789 811 0.98

17 18 0.00081 0.05 13.7 3.4 1 23 821 843 821 843 0.97

18 18 9.2e-06 0.00057 19.8 1.6 1 23 849 872 849 872 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.2e-05	0.0014	18.6	2.1	1	23	367	389	367	389	0.97
2	18	7.2e-06	0.00045	20.1	0.4	1	23	395	417	395	417	0.97
3	18	0.0011	0.066	13.3	0.9	1	23	423	445	423	445	0.95
4	18	4.6e-06	0.00028	20.7	2.7	1	23	451	473	451	473	0.97
5	18	3.5e-05	0.0022	18.0	4.7	1	23	479	501	479	501	0.99
6	18	6.3e-05	0.0039	17.1	5.7	1	23	507	529	507	529	0.97
7	18	3.1e-07	1.9e-05	24.4	4.3	1	23	535	557	535	557	0.98
8	18	1.1e-07	6.9e-06	25.8	2.4	1	23	563	585	563	585	0.97
9	18	6.5e-05	0.004	17.1	6.7	1	23	592	614	592	614	0.97
10	18	0.00011	0.007	16.4	6.5	1	23	620	642	620	642	0.98
11	18	1e-05	0.00063	19.7	4.5	1	23	648	670	648	670	0.98
12	18	7.7e-06	0.00048	20.0	7.9	1	23	676	698	676	698	0.98
13	18	5.7e-06	0.00035	20.4	7.8	1	23	704	726	704	726	0.97
14	18	6.7e-07	4.1e-05	23.4	7.7	1	23	732	754	732	754	0.98
15	18	0.00021	0.013	15.5	9.5	1	23	760	783	760	783	0.95
16	18	7.4e-05	0.0046	16.9	0.9	1	23	789	811	789	811	0.98
17	18	0.00081	0.05	13.7	3.4	1	23	821	843	821	843	0.97
18	18	9.2e-06	0.00057	19.8	1.6	1	23	849	872	849	872	0.96

Sequence Information

Coding Sequence: ATGTCGTCGTCATCGAGAAACACAGTCGCCGTCATAGCTGCAGCCCAGGAACAaaaccagcaacagcaacatcgacaacagcagcaacagcaaccacagctAAACAACGACAAAGTTACAGCACTTGCGACACagcaaaatTTGAATCCTAAGTATTGGCTGTTACCGGATttagcagctgcagcagcaacaggcaGTACATTAACCCATGTGAACGGTCTAGGACAGCAGCAATCACAACATATACATGGAACAATCAGAAGTGACGACAGCGCccgagagcagcagcagcaacagcaatatgtAGGAGCGttgcagccacagcagcagcagcagaacgcCATAGAAATCAAGGAGGAGCGGCAACAAGCTGCCTCAAATACACATACTACTACTGCAAGGAACAAGGAACCAACAGGACttgagcaacaacagcagcaacaacaacaacatcaacagcagcatctTATTATGCAGCACGTGAGCGCCGCAAGCTCAGTGCCTTCGGTGGTTGCACCGGTGGTAACGACTGGCGGCGGCACAACGATAACACTTGGCGGAGCACCACCATTGCCAACTACCAAGTCAGAGATCAAAGAGGACGGCAAACCGCCACACAGCATTGAAATGTATAAAGTCAATATTgaggacatttcacaattgttTACGTATCACGAGGTGTTTGGAAAAATTCACGGTGATGTTGTGAATCATCAATTGGCGGCGGCGCACAGTGGTCAATTGCCACCGCCGCCCCCCTTGCCACCACAAACGCATGTCACGTCAGCTGCTGCAGCGGCAGCATCCACCAATAATGCAGCGGTAGCTGCTGTGATGGCCTCAGCAAAtgcggcagcagctgctgcagcgGCAGCATCAGCCGCCTCGGCGCCGGTGACGACAACAACGTCTAGCGGTGGTGCCGGCGGACAACAGACCACGTCCACAGTGACCACTACAGGGGGCGgtagcggcggcggcggcagcacgAGCACGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATACATGGTGTCGATGGGCAGTCGACTGTGACGCTAGCACCGGATGGCACGCCCATAGCAACGGGTACCCATGTCTGCGATATATGCGGCAAGATGTTCCAGTTTCGTTATCAGCTGATCGTGCATCGTCGCTATCATAACGAACGGAAACCGTTCATGTGTCAGGTGTGCGGTCAGGGGTTCACCACATCCCAGGATTTGACGCGTCATGGCAAGATACACATTGGCGGTCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTTGCGAATAACACAAGTCTGGAGCGGCACATGAAGCGACATTCGACGGACAAGCCGTTCGCCTGCTCCATTTGTCAGAAGACATTCGCACGCAAAGAGCATTTGGATAATCATTATCGTTCGCACACCGGTGAAACACCGTTTCGTTGCCAATACTGTGCTAAGACGTTTACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCATCTAGCCAATCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATCCTCTGGCATACAGCAGGCGAGACTCCGCACCGCTGTGACTTTTGCTCCAAGACGTTCACGCGCAAGGAGCATCTGCTTAATCATGTGCGCCAGCATACCGGAGAGTCGCCGCACCGCTGCTCGTACTGCATGAAGACGTTCACACGCAAGGAGCATCTGGTGAACCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACCTACTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCTCCTACTGCACAAAGACGTTCACGCGCAAGGAGCATCTAACGAATCATGTGCGCCAGCATACGGGCGACTCACCGCATCGGTGCACCTACTGCAAGAAGACCTTTACGCGGAAGGAGCACTTGACGAACCACGTGCGCCTCCATACGGGAGACTCGCCGCACAAATGCGAATACTGTCAGAAGACATTCACGCGCAAGGAACATCTGAATAATCATATGCGCCAGCACTCGAGCGACAATCCGCACTGCTGCAATGTGTGCAACAAGCCCTTTACACGGAAGGAGCATCTTATCAATCATATGTCCCGTTGCCACACCGGAGATCGTCCCTTCACATGCGAGACTTGCGGCAAATCGTTTCCACTTAAGGGTAATCTGTTGTTCCATCAGCGCAGTCATACGAAGGGACAGGAGTGCGAGCGTCCGTTTGCCTGTGAGAAGTGCCCGAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGGTCCCATTCGGGCGAGAAACCGCACGCCTGCACTCTGTGCAGCAAAGCTTTCGTCGAGCGTGGCAATTTGAAGCGCCACATGAAGATGAACCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAAGAAGTGAAACCGATCATAATTCCCCACCAATCGACGACCACAATGCACACCATTCAACAGATAACTGCAGGAGCTGCCGCCGGTGCCAATGCCGTTCAGTTAACGCCTGGGCTAGTACCGCTCGTCACATCGACCCTCATCTCGCACAATGCCCAGCAGCAATcgcagaaacagcagcagcaacaacaacaacagcagcagcagcaacaacaacagcaacaagcggCTGCCCAACAGCAGGCAGCTCAGCAGCAAGCGGCCGCCGCACATCAGCAGCAAGTGGCagtacagcagcaacagcaagcggcggcagctgcagctgcggcgcatcaacaacaacagcaacagttgcagcaacaacagcaattgttGCAGCTGTCCATCCAGCAGGCAGCGCATCaccatcaacagcagcaacaggagcagcatcgtcagcatcagcagcaacatcatcaggcgcagcaacagcaccaagGTCACCCGCAagcgccgccaccgccacagcagcaacagcagccgccaCCACAAGTGCCAATTGCACTGATCAGTGATCCAAGCGCGCTGGCACGCGCTGCCATGCAATTGCAGCATTTGCCGGCCAATGTGGAACAGCATCCAGTGGTTTACTAA
Protein Sequence: MSSSSRNTVAVIAAAQEQNQQQQHRQQQQQQPQLNNDKVTALATQQNLNPKYWLLPDLAAAAATGSTLTHVNGLGQQQSQHIHGTIRSDDSAREQQQQQQYVGALQPQQQQQNAIEIKEERQQAASNTHTTTARNKEPTGLEQQQQQQQQHQQQHLIMQHVSAASSVPSVVAPVVTTGGGTTITLGGAPPLPTTKSEIKEDGKPPHSIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHQLAAAHSGQLPPPPPLPPQTHVTSAAAAAASTNNAAVAAVMASANAAAAAAAAASAASAPVTTTTSSGGAGGQQTTSTVTTTGGGSGGGGSTSTGELLMPKMEGGIHGVDGQSTVTLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHNERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACSICQKTFARKEHLDNHYRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCSYCTKTFTRKEHLTNHVRQHTGDSPHRCTYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHQSTTTMHTIQQITAGAAAGANAVQLTPGLVPLVTSTLISHNAQQQSQKQQQQQQQQQQQQQQQQQAAAQQQAAQQQAAAAHQQQVAVQQQQQAAAAAAAAHQQQQQQLQQQQQLLQLSIQQAAHHHQQQQQEQHRQHQQQHHQAQQQHQGHPQAPPPPQQQQQPPPQVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560429;
90% Identity: iTF_00336928;
80% Identity: -