Aplu085128.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anthophora plumipes
Gene Symbol
lola
Assembly
GCA_951804975.1
Location
OX638112.1:28374785-28376899[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.3e-24 5.5e-21 77.5 0.0 3 100 31 124 29 126 0.94

Sequence Information

Coding Sequence
ATGTCTGAGATTGTTAACCAACATGAGATTAATCAGAGCTACTGGTTTAAATGGAATGACTATCAGAATCATTTGTCCGATGTAGTTAGACAACTTTTGGAGGAGGATTGTATGGTGGACGTTACTCTGGCTGCTGCTGGAGAACGTATTCATGCTCATCGCATAGTTCTCTGTGCTTGCAGCACTTTATTTCGAGAGATATTGAGTCAAGTGAACGAAGACCACCCAACAATAATATTAAGCGATATATCTGCACAGGATATAAAATCTATCATAGAATTCACTTATCATGGAGAAGTGAGGGTTCCTGTTGAGAATATTAGCAGTTTATTAGATGCAGCACGTTCATTAAAAATTTGTGGTCTTATCGAGATTGATGGGCTTGATGAAAGTGACTCTATTGCAAGTGCTAAAGATTTCAATGATAATAATGAAGAGCCGATGACTGTAATTAGTGAGAGtgaagaaaatgtaataaatacatTGCAACATGATTATGAGGATTTAGAGGATCAACAGAAACAAGAGATTGAAAATTCCACTtcgcataaaaaaaagaaacgcagaCGCGACACGACGAAAAGGGATTACAGCGATGATATGCTAGCGTCGGCAATTAATGACTTGAAGACCGGTCAAACATTGATAGAAGCTTCTACTAAGCATAACATACCGCGTTCAACTTTGTACATGCGTGCTAAAGCATTAGGTATACATTTAAACGCGTCGAGAAATGAATATCCCGCGGAATGTATGAAAGCTGCTATAAATGCGGTAATTGGTGGATCAAGTTTGCAACATGCATCGGAAATGTTTAGTATACCAAAAACAGTTTTATGGAGAAGGATTCAGAAAGAAGGCTATCAAATATTACGTTCTGAAATGAAACGGTCTTACGGTTCCGATAAACGAGAAGCTGCGGTTAAAGCTCTGGAAAGGGGAGAAAATTTAACTAAAGTTGCTCTCGAATTCAAAATTCCGAAGACCACTTTATTCAGGGATAAAGCTCGATTGGTGGACGAGGGAAAACTGCCGTTATCATTTTGGAAGAAGCGTAAAACGGAAAATGAAGAGTTAAAAAAATCTCGATTAGAAGAAGCTGTTGCTGCTTGCAAAGGAGGAAAAATGTCACAGGCAGCAGCGTCGATGACTTATCATATTCCAAAGACTACTATATGGAGACGTCTTCAACAGGATGGTAAAAAGTCAGAGCGTTCGTTGAACTTGAAAAAGCAAAGAATAACGGACTCTAAACATAATCCGGAAGCGAAAGTACAGGAAGGATCTGATTTTACGTACTGTGAGgTTTCATCGGAAATTCCTATAACTTACATAGATGAAAATAGCATACCTGAagattctgtgataatattaacAGCAGAAGATATGGACGGTCTTAATTTAGAAGAAGGACGACAAATTATTGTTAATTCAgaATCAGGACAAGAGTATGTTCCTTGCGCTATAAGTATCGAGGAAAATTCAAATTACTCTCAGACAGAAAGTTAG
Protein Sequence
MSEIVNQHEINQSYWFKWNDYQNHLSDVVRQLLEEDCMVDVTLAAAGERIHAHRIVLCACSTLFREILSQVNEDHPTIILSDISAQDIKSIIEFTYHGEVRVPVENISSLLDAARSLKICGLIEIDGLDESDSIASAKDFNDNNEEPMTVISESEENVINTLQHDYEDLEDQQKQEIENSTSHKKKKRRRDTTKRDYSDDMLASAINDLKTGQTLIEASTKHNIPRSTLYMRAKALGIHLNASRNEYPAECMKAAINAVIGGSSLQHASEMFSIPKTVLWRRIQKEGYQILRSEMKRSYGSDKREAAVKALERGENLTKVALEFKIPKTTLFRDKARLVDEGKLPLSFWKKRKTENEELKKSRLEEAVAACKGGKMSQAAASMTYHIPKTTIWRRLQQDGKKSERSLNLKKQRITDSKHNPEAKVQEGSDFTYCEVSSEIPITYIDENSIPEDSVIILTAEDMDGLNLEEGRQIIVNSESGQEYVPCAISIEENSNYSQTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00117916; iTF_00963105; iTF_00964385; iTF_00964579; iTF_00963944; iTF_00961930; iTF_01122988; iTF_00961741; iTF_01122351; iTF_00962612; iTF_00962422; iTF_01123161; iTF_01122555; iTF_00963774; iTF_00963296; iTF_00219713; iTF_00625602; iTF_00625415; iTF_00219894; iTF_00225153; iTF_00217666; iTF_00231906; iTF_00222438; iTF_00223978; iTF_00224651; iTF_00214317; iTF_00219213; iTF_00223789; iTF_00233326; iTF_00230127; iTF_00232079; iTF_00217843; iTF_00219028; iTF_00214486; iTF_00224470; iTF_00225335; iTF_00229945; iTF_00233145; iTF_00223293; iTF_00222622; iTF_00223102; iTF_00228067; iTF_00227878; iTF_00215625; iTF_00215804; iTF_00228579; iTF_00228772; iTF_00226694; iTF_00226511; iTF_00220679; iTF_00220497; iTF_00217170; iTF_00216989; iTF_00684715; iTF_00684872; iTF_00216496; iTF_00216304; iTF_00221361; iTF_00230615; iTF_00221179; iTF_00230781; iTF_00684084; iTF_00684257; iTF_00229270; iTF_00229450; iTF_00231414; iTF_00231233; iTF_00232694; iTF_00232530; iTF_00676119; iTF_00675938; iTF_00227192; iTF_00227371; iTF_00226011; iTF_00225829; iTF_00214940; iTF_00215122; iTF_01512929; iTF_01233765; iTF_01512105; iTF_01234449; iTF_01512753; iTF_01234264; iTF_01235128; iTF_01512282; iTF_01233564; iTF_01234944; iTF_00086082; iTF_00087302; iTF_00087847; iTF_00087017; iTF_00088940; iTF_00085517; iTF_00085200; iTF_00088150; iTF_00086424; iTF_00088696; iTF_00084445; iTF_00084669; iTF_01065475; iTF_01069571; iTF_01070467; iTF_01070276; iTF_01067045; iTF_01067717; iTF_01068201; iTF_01066859; iTF_01067531; iTF_01065677; iTF_01069774; iTF_01066160; iTF_01068400; iTF_01069080; iTF_01068890; iTF_01066366; iTF_00303207; iTF_00302945; iTF_00864555; iTF_00864739; iTF_00360129; iTF_00865922; iTF_00965955; iTF_00762468; iTF_00966116; iTF_00184037; iTF_00863365; iTF_00024711; iTF_00864073; iTF_00861994; iTF_00860300; iTF_00866796; iTF_00361006; iTF_00763152; iTF_00865232; iTF_00865427; iTF_00183860; iTF_00860500; iTF_00863189; iTF_00183382; iTF_00024536; iTF_00861048; iTF_00360825; iTF_00861273; iTF_00762650; iTF_00360315; iTF_00863868; iTF_00763327; iTF_00866111; iTF_00866623; iTF_00983533; iTF_00983685; iTF_01419555; iTF_00982884; iTF_01418918; iTF_01420359; iTF_01418442; iTF_01417804; iTF_00982383; iTF_01419088; iTF_00873715; iTF_01417619; iTF_01419732; iTF_01420852; iTF_00983061; iTF_01418267; iTF_00982206; iTF_01421023; iTF_00873888; iTF_01420192; iTF_01513390; iTF_01514922; iTF_01513584; iTF_01090098; iTF_01514259; iTF_01089911; iTF_01514746; iTF_01514075; iTF_00140684; iTF_00141749; iTF_00140502; iTF_00141920; iTF_00222000; iTF_00221840; iTF_00218333; iTF_00218524; iTF_00761072; iTF_00760906; iTF_01454290; iTF_01453993; iTF_00862675; iTF_00861793; iTF_00183203; iTF_00862478; iTF_00306166; iTF_00306379; iTF_01255799; iTF_00393697; iTF_00393514; iTF_01255456; iTF_01424475; iTF_01424283; iTF_01169084; iTF_01169271; iTF_01071101; iTF_01070950; iTF_01539519; iTF_01539706;
90% Identity
iTF_00963105;
80% Identity
iTF_00117916;