Dmoj016002.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Drosophila mojavensis
Gene Symbol
-
Assembly
GCA_018153725.1
Location
JAECYD010000073.1:8257283-8259610[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.7e-15 4.7e-13 49.3 0.0 3 99 22 116 20 121 0.90

Sequence Information

Coding Sequence
ATGAATCACCTGAAATGGATGGGCCACTCGTCCACAATAATGGATATACAGCGCGTTCTGCTACATCAACAAAGCAACAATCAGCAATGCGAAGTATTGCTTGTGGCCAAAGATGGCATCAGCGTACGCGCCCATCTCTTCGTTTTAAGCACTTGCAGCGATTTAATGCGCAATCTGCTTGTCGATTTACCCGCCGGTCAGGAAGCGACTGTCATTTTGCCGGACATCCGTGGAGAGCTGCTCGAGAATGTTCTATCGTTTATTTATATGGGGGAAACTAGTTTGACCTCTGCCCTGCTACCCGAGTTTCTGGGGGCCATAAATTTACTGGGCATCAAATCTGCCATAAGCTTTGATACCAATCCAACATCCATGACGACCTCAAGTGTTATAAGTGGCGCTATGGCTGTCGAAGAAGCCAAATCAATAAGCGGCTTACATATTGCTAATACTGCGCTTATGGAGGAGGAGGAAGAAGAGGATGCCGGAGCTGTTGTCGGTAAATTGGAAGTGGATAATGCCGTACTCACAAATCCTCAACAACAACACGAGCAGGAAGGCCGAACCCTGGAATTCCTAGATGTTTACAGCGAACAGCCCAAAATCACATATTCAATCGAACACATGGGCGGCACAACCAGTGGAAATCAGTATATATATACAGAGAACACGGGAACGTATACCATAACACAGTCATCCGTAGGAAAGTTGGGAGTGCAAGGCAGCTCAGCTGTGGTCGACTCAGTGGAGACAGCTGAGCTAGGTGACGAGGATGTCGAGGCTGAGGTCACAGACGAGCACGAAGAATCCGAGTCACAATTAATCGAGGAAGAATATGTTGGATCGGCAGATCCTTTAATAGAGATGAGCGCAGTGGCGGATGTTGATATGCACGAGGATGGAATGCATGACGGAGACGAGGAGGAGGATGATGAGCTATTGGATGTAAAACCTCGTAAATCTCAGCTCGATATGAAAATTTTAAAATTCAAGGCCCGCCAGCGTCCAGCATCATCGAAAGCAATAAAGAAAGCAATGACCAAACAGCATCAGCAGCACGCAGCGCTTAAAAAAGAATGTAAGGAAGATCTCAATGATGCCCTCGACCTCGCAGCGGCTGCGGTTCTTCACGAAGGCCTCAGCTTGCAGAAAGCTGCTGATCGCTACGACATATCGAAAACCGTACTATGGCGACGTGTGCGCTCGAATCCAGCCTACATGAGAATAAAACGAGAGAAACCTTCGCTTTCGGAAGCATATGAACGCCTAAGGAACGGCGACTCATTGAAAAGCATAAGCCAGGATCTGCATATACCCATGTCGACGCTGCATCGGCACAAAGTGCGTCTGGCCGCACAGGGCCGCCTGCCCCACTTTGTTGCTTGCCGGCGGCGTGACAGTACCCCAAAGGATGAGCTGCGTGAGAAGCTAGCAAAGGCAGTGCATGCCTGCATCAACGATGGCATGACCCAAAATCATGCAGCCAATCTCTTTGAAATACCTAAGAGCACGCTCTGGCGGCACTTGCAACGGCGAACAACCGAGGCGGGGCGTAAAGTCAAGGAGGAGCATGAAGAAGAGGATGATATGAATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTAAACACCTTGCGATTGTAGAAATAATGTAG
Protein Sequence
MNHLKWMGHSSTIMDIQRVLLHQQSNNQQCEVLLVAKDGISVRAHLFVLSTCSDLMRNLLVDLPAGQEATVILPDIRGELLENVLSFIYMGETSLTSALLPEFLGAINLLGIKSAISFDTNPTSMTTSSVISGAMAVEEAKSISGLHIANTALMEEEEEEDAGAVVGKLEVDNAVLTNPQQQHEQEGRTLEFLDVYSEQPKITYSIEHMGGTTSGNQYIYTENTGTYTITQSSVGKLGVQGSSAVVDSVETAELGDEDVEAEVTDEHEESESQLIEEEYVGSADPLIEMSAVADVDMHEDGMHDGDEEEDDELLDVKPRKSQLDMKILKFKARQRPASSKAIKKAMTKQHQQHAALKKECKEDLNDALDLAAAAVLHEGLSLQKAADRYDISKTVLWRRVRSNPAYMRIKREKPSLSEAYERLRNGDSLKSISQDLHIPMSTLHRHKVRLAAQGRLPHFVACRRRDSTPKDELREKLAKAVHACINDGMTQNHAANLFEIPKSTLWRHLQRRTTEAGRKVKEEHEEEDDMNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKHLAIVEIM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00554306; iTF_00545157; iTF_00545350; iTF_00551690; iTF_00479403; iTF_00559596; iTF_00516176; iTF_00551504; iTF_00473170; iTF_00559410; iTF_00516371; iTF_00554486; iTF_00520023; iTF_00544599; iTF_00472984; iTF_00540475; iTF_00544411; iTF_00549468; iTF_00479583; iTF_00519839; iTF_00540288; iTF_00475138; iTF_00526498; iTF_00550818; iTF_00534500; iTF_00490885; iTF_00506220; iTF_00490701; iTF_00506029; iTF_00563278; iTF_00550991; iTF_00531059; iTF_00563095; iTF_00475321; iTF_00530874; iTF_00526683; iTF_00534686; iTF_00547459; iTF_00495778; iTF_00541862; iTF_00547279; iTF_00541684; iTF_00567638; iTF_00495965; iTF_00567456; iTF_00572517; iTF_00572705; iTF_00532486; iTF_00532293; iTF_00499688; iTF_00596041; iTF_00499505; iTF_00518545; iTF_00518360; iTF_00595867; iTF_00519080; iTF_00519270; iTF_00502442; iTF_00502629; iTF_00546570; iTF_00546759; iTF_01552554; iTF_01554066; iTF_01552376; iTF_01553887; iTF_00514283; iTF_00570498; iTF_00522090; iTF_00577163; iTF_00570317; iTF_00522319; iTF_00514098; iTF_00576981; iTF_00525046; iTF_00525271; iTF_00583065; iTF_00582880; iTF_00568171; iTF_00568360; iTF_00575499; iTF_00575502; iTF_00575700; iTF_00575702; iTF_00588755; iTF_00588941; iTF_00537429; iTF_00537615; iTF_00548725; iTF_00548935; iTF_00566709; iTF_00566917; iTF_00573237; iTF_00573427; iTF_00593013; iTF_00593225; iTF_00582358; iTF_00582181; iTF_00598070; iTF_00598261; iTF_00508247; iTF_00508449; iTF_00616823; iTF_00617007; iTF_00482361; iTF_00482151; iTF_00510457; iTF_00601697; iTF_00601923; iTF_00557828; iTF_00608552; iTF_00558025; iTF_00608361; iTF_00583599; iTF_00583795; iTF_00586070; iTF_00510653; iTF_00585886; iTF_00564571; iTF_00564760; iTF_00538332; iTF_00538150; iTF_01553340; iTF_01553104; iTF_00493565; iTF_00599501; iTF_00599694; iTF_00493758; iTF_00512829; iTF_00512641; iTF_00560958; iTF_00561140; iTF_00476543; iTF_00476732; iTF_00513567; iTF_00513377; iTF_00530367; iTF_00530186; iTF_00586783; iTF_00586596; iTF_00509920; iTF_00509736;
90% Identity
iTF_00546570;
80% Identity
iTF_00549468;