Basic Information

Insect: Drosophila histrio
Gene Symbol: -
Assembly: GCA_958299025.2
Location: OY282581.2:25901948-25905126[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.7e-06 0.00076 20.1 1.4 1 23 222 245 222 245 0.93

2 17 0.00076 0.059 14.1 1.8 1 23 252 274 252 274 0.98

3 17 0.24 19 6.2 0.7 2 23 306 327 305 327 0.94

4 17 0.0044 0.35 11.7 0.9 3 23 419 440 417 440 0.96

5 17 0.07 5.5 7.9 0.5 1 19 447 465 447 468 0.93

6 17 0.023 1.8 9.4 5.1 1 23 477 499 477 499 0.95

7 17 5.3e-05 0.0042 17.7 0.5 1 23 506 529 506 529 0.96

8 17 0.00046 0.036 14.8 2.6 2 23 537 558 536 558 0.96

9 17 0.0082 0.64 10.9 0.0 2 21 585 604 584 605 0.94

10 17 0.012 0.94 10.3 1.8 1 23 658 681 658 681 0.96

11 17 0.014 1.1 10.1 0.5 1 23 718 741 718 741 0.95

12 17 0.00014 0.011 16.4 1.6 2 23 769 791 768 791 0.95

13 17 0.00091 0.071 13.9 0.3 1 23 805 827 805 827 0.95

14 17 9.9e-05 0.0078 16.9 1.8 1 23 833 855 833 855 0.99

15 17 3.7e-07 2.9e-05 24.5 2.6 1 23 861 883 861 883 0.98

16 17 7.4e-05 0.0058 17.3 6.4 1 23 889 911 889 911 0.97

17 17 0.0023 0.18 12.6 0.2 1 23 917 941 917 941 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.7e-06	0.00076	20.1	1.4	1	23	222	245	222	245	0.93
2	17	0.00076	0.059	14.1	1.8	1	23	252	274	252	274	0.98
3	17	0.24	19	6.2	0.7	2	23	306	327	305	327	0.94
4	17	0.0044	0.35	11.7	0.9	3	23	419	440	417	440	0.96
5	17	0.07	5.5	7.9	0.5	1	19	447	465	447	468	0.93
6	17	0.023	1.8	9.4	5.1	1	23	477	499	477	499	0.95
7	17	5.3e-05	0.0042	17.7	0.5	1	23	506	529	506	529	0.96
8	17	0.00046	0.036	14.8	2.6	2	23	537	558	536	558	0.96
9	17	0.0082	0.64	10.9	0.0	2	21	585	604	584	605	0.94
10	17	0.012	0.94	10.3	1.8	1	23	658	681	658	681	0.96
11	17	0.014	1.1	10.1	0.5	1	23	718	741	718	741	0.95
12	17	0.00014	0.011	16.4	1.6	2	23	769	791	768	791	0.95
13	17	0.00091	0.071	13.9	0.3	1	23	805	827	805	827	0.95
14	17	9.9e-05	0.0078	16.9	1.8	1	23	833	855	833	855	0.99
15	17	3.7e-07	2.9e-05	24.5	2.6	1	23	861	883	861	883	0.98
16	17	7.4e-05	0.0058	17.3	6.4	1	23	889	911	889	911	0.97
17	17	0.0023	0.18	12.6	0.2	1	23	917	941	917	941	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGCCGTACTTGCGATGCAAGGGACGCAGATAAACTGTATAAGTTGGCCACGGCCACCAAAAGGTTCCCGGATAAGCTGCTCTCGGATATTTTAGCTGAATTAACACACATCGATGTGAACGATTCGTTATCACAGCGGCTGCCTCAGTGTGTATGCGGCACCTGCGCAAGAAAACTAATCGGAGCCTATTACTACATAAAACAGGCGGTGGCAGCCAATGAACTGTTGATGAACCACGTCCATACCACACCGCACGACAAAGCCGTGGCCAATGACTGCCTACAGGAAGTGCCCATGGAGCTGTGTGCCGAGCAACATGTTGAGGTTAAATTGGAAACAGAGGAAGATGAAATTGACAACGATATAACGTGTACGGAACTGCCCGAATtcacaacaacacaaattaCCAATGATGTGGACAACACAGTGGAAAGTGATCTCGATAACAAAAAGTCTACCGATCCATTGACAATGCTTGATCCCGTCAAGCAGGAAGAGAATGGAGTGCCAACAAGAGCCGCGATTGTCCAGGAGCAGAAATATAAGTCTGATAATGATGACGATTCACTCGATGATTTGCCTTTACAACAGCGTGTACAAAAGTGGAAGCAGACGGATAAACTGCGTGGGCTTAAAAGACAGATATTCGCGTGCAAGGAATGTCCCAAGAGCTTCAAACGCCCGAGATATCTAAAGCAGCATTCGTCGCGCGTCCACAAGTCGAAGTCGGGCTGGTATTCATGCTCCTTCTGTATACGAAAGTTCAGCCACAGTGAAGCTCTCCAGGCGCATCTAAAAGTGCACGGAGACTCCAAACGGTCCGCCAATTTGGGCGAGAGCAAAAAGGCCAAGGATATTGATGTGAACGTGTGCAAACCACATGGCTATAAGCTTATCGAGTGCATGATCTGCCAGAGTCAATACGATAAGATTGCCCATCTGCGACGTCACCTTGAGCAGCATCCTGAAATTGTTAACTTCGGTGCACGATCGAATATGCAACCAAATGAGCTGGCAGAACTGTTCTATCCAGATGCCAAGGATGTGAGTGAGGATCAGTTAAAGCAACTTATACGCAAAGATTTGGAAGCGGGCATTTATCAGCGTTTCTATTCGATAACGAACCAATCGGGCTACGAAATGGATCTCGACAGCTCCGAAACAGAAAGTGAGGCCGAACTGGATGGCGATGAACAGTCGAGGCAACAGCGCTACAAACCCAGAGCCAAGTACGGCTGCGAGCTGTGTCAGGAGCGTTATCAACGCAAGTATCAGCTGTATGAGCACCAGCGTCAAACGCATGCCTGGCTAGATGCTCCCCATGTGTGTGGCCGCTGTGATGCACGCTTTGTTAGCCTCCAGCTGCTGCGGCACCACAATGAATCGCAGTGCAAGAACTCCCAGAAACGTTTCCTGTGCCACAAATGCCCGTTGCGCTTCCGCTGGCGGCACAATCTGAAGGTGCACACACGGGAGCACAGAATCACAAACCAAACATTCGAGTGCGTCGATTGCAAGCGCGTCTTTGACAAGAAGAAGTCCCTGACGGTCCATTTGCTGAGTGTGCATGCCGAGGAATCGAAACTGATACCGTGTCAATGGTGCACTCGCAAGTTCTATCGACACGATTATCTGGTGAAGCATCTGAAGCGACACGGCATCCGGGAGCAAGATATTCCGCTGGCCGAGACGCTAATTGCGGCCACATCGAAGCCAAATGGAATCAAACGGATCACCTGCAAGATCTGCAACCTGCAATTTGAACGCATCATTGATCTGCGTGCTCACATTCAGCTGGAACTGAAGCTGGCGCTGTCACTGCATCAGAACTATGACTCCCCGCACAACTACTCCATAACGAATGAATCCGGATATGAGTTGCAGCTCGGCGACTCGGAGACGGAGGATGAGATGCAGCTGCAGTCAACGCCCACGACAACTCCACGTCTCGTCTACATTTGCGAACTGTGCAAAGTGCAGTGCAGGCGGAGGTACGAGATGATACAGCATCAGCGTGCCATGCATCGTTTTGACAAGATGCCACACGAGTGCGAGGTGTGCATCTTCAAGTGTGTCTGCAAGAGCATCATGGATCAGCACAGGCAATCGCAGTGCCACAGCGCAGAGAAGAAATACGCGTGCAGCAGATGCAGCTACAAGTTCATGTGGCCCGAGAATCTGCAACAAcacatgcaactgcaacacggCGGCCTGGAACGTGCCCCAAGTGCTGATCGCATACCAGACGATCCCGCCGATCCGGTGGATGCAACATTACAGCTGCTGCAATGTCCGCACTGTGATCGCACCTATCAAATGAAATCACGACTGAACAATCACATACGGGATGTGCACATCAATGGGGATCGCAAACGCAAGGAGGCCATCAAGAAGTTCCTCTGCTCGCTGTGTGGCCGCGAGACGCAATCGGCGGCCACTTTGGTCACCCACATGCGTCGCCACACGGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAAATGGCATTTCCACGGCACTCGGAAATGACATCACATCGCAGAATGCACACGGGAGAGAAACCATTCCACTGCACAGTTTGCGGCAAGGACTTTGCACGCTCCGACAAGCTGAAGCGACACATGCTCACCCACAGCGGACTAAAGCCGCACAAGTGCACGTACTGCGACAAGTGCTATCGCCAGGCCAAGGATCTGAAGTTGCATTTGCAGCAGCACACCGGCGAGTGCCCCTTCATATGTGGCACGTGTGGCGAGCGATTCATTCAGGGCACGGCGCTGGAGAAGCATCGCATGATGCGTCGTCACTTCGACGAGGTGGATGAACGCGGCTCAACGCAAACATTGACCGCATAA
Protein Sequence: MKLPVMCRTCDARDADKLYKLATATKRFPDKLLSDILAELTHIDVNDSLSQRLPQCVCGTCARKLIGAYYYIKQAVAANELLMNHVHTTPHDKAVANDCLQEVPMELCAEQHVEVKLETEEDEIDNDITCTELPEFTTTQITNDVDNTVESDLDNKKSTDPLTMLDPVKQEENGVPTRAAIVQEQKYKSDNDDDSLDDLPLQQRVQKWKQTDKLRGLKRQIFACKECPKSFKRPRYLKQHSSRVHKSKSGWYSCSFCIRKFSHSEALQAHLKVHGDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIAHLRRHLEQHPEIVNFGARSNMQPNELAELFYPDAKDVSEDQLKQLIRKDLEAGIYQRFYSITNQSGYEMDLDSSETESEAELDGDEQSRQQRYKPRAKYGCELCQERYQRKYQLYEHQRQTHAWLDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHTREHRITNQTFECVDCKRVFDKKKSLTVHLLSVHAEESKLIPCQWCTRKFYRHDYLVKHLKRHGIREQDIPLAETLIAATSKPNGIKRITCKICNLQFERIIDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQLQSTPTTTPRLVYICELCKVQCRRRYEMIQHQRAMHRFDKMPHECEVCIFKCVCKSIMDQHRQSQCHSAEKKYACSRCSYKFMWPENLQQHMQLQHGGLERAPSADRIPDDPADPVDATLQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMTSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKCYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGSTQTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490913; iTF_00508484; iTF_01556254; iTF_00495265; iTF_00566945; iTF_00570529; iTF_00610049; iTF_00620001; iTF_00496770; iTF_00599010; iTF_00597539; iTF_00548964; iTF_00552452; iTF_00499717; iTF_00521541; iTF_00528197; iTF_00558885; iTF_00593253; iTF_00499014; iTF_00517126; iTF_00485991; iTF_00577191; iTF_00485992; iTF_00596072; iTF_00616329; iTF_00500458; iTF_00514315; iTF_00535467; iTF_00497548; iTF_00543884; iTF_00518574; iTF_00498288; iTF_00522352; iTF_00542576; iTF_00522353; iTF_00501938; iTF_00525298; iTF_00557331; iTF_00560436; iTF_00564789; iTF_00607221; iTF_00482390; iTF_00525302; iTF_00553177; iTF_00583098; iTF_00574203; iTF_00513597; iTF_00511423; iTF_00570527; iTF_00576479; iTF_00546786; iTF_01551137; iTF_01557700; iTF_01550411; iTF_01559931; iTF_01551869; iTF_01553381; iTF_01558437; iTF_01559177; iTF_01556973; iTF_01554100; iTF_00892067; iTF_01548996; iTF_01548999; iTF_01552588; iTF_01552589; iTF_01554102; iTF_00538370; iTF_00584546; iTF_01324292; iTF_01322075; iTF_01325061; iTF_01327302; iTF_00803751; iTF_00587546; iTF_00805338; iTF_01549703; iTF_00551016; iTF_01325800; iTF_00553834; iTF_00562597; iTF_00556639; iTF_00472485; iTF_00595377; iTF_00579412; iTF_00588973; iTF_00530407; iTF_00561168; iTF_00495991; iTF_00598289; iTF_00541886; iTF_00567666; iTF_00547487; iTF_00901645; iTF_00585353; iTF_00471018; iTF_00478877; iTF_00569119; iTF_00802989; iTF_00601966; iTF_00586097; iTF_00533982; iTF_00523094; iTF_00510680; iTF_00537648; iTF_00832318; iTF_01321326; iTF_00610799; iTF_00614319; iTF_00589671; iTF_00509234; iTF_00520764; iTF_01322799; iTF_01323522; iTF_00531088; iTF_00507025; iTF_00528964; iTF_00575744; iTF_00558065; iTF_00583843; iTF_00608593; iTF_01356273; iTF_00582387; iTF_00568388; iTF_00493793; iTF_00532513; iTF_00512866; iTF_00545379; iTF_00502660; iTF_00559625; iTF_00599721; iTF_00551722; iTF_00554510; iTF_00573455; iTF_00549681; iTF_00516402; iTF_00520050; iTF_00544626; iTF_00540503; iTF_00479610; iTF_00509946; iTF_00572731; iTF_00586814; iTF_00473198; iTF_00476760; iTF_00526712; iTF_00506252; iTF_00475350; iTF_00563308; iTF_00617039; iTF_01328025; iTF_00534714; iTF_01320603; iTF_01326584; iTF_01554848; iTF_01559176;
90% Identity: iTF_00507025;
80% Identity: -