Danc007976.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila anceps
Gene Symbol
-
Assembly
GCA_035045945.1
Location
JAWNON010000140.1:3067868-3071271[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 3.9e-06 0.00027 21.2 0.7 1 23 220 243 220 243 0.95
2 17 0.00075 0.053 14.0 2.9 1 23 250 272 250 272 0.98
3 17 0.37 26 5.6 0.1 2 23 304 325 303 325 0.94
4 17 0.0044 0.31 11.6 5.2 1 23 414 437 414 437 0.97
5 17 0.087 6.1 7.5 0.2 1 19 444 462 444 464 0.95
6 17 0.0073 0.51 10.9 4.0 1 23 474 496 474 496 0.95
7 17 2.1e-06 0.00015 22.0 0.8 1 23 503 526 503 526 0.97
8 17 9.1e-05 0.0064 16.9 1.2 2 23 534 555 533 555 0.96
9 17 0.0058 0.41 11.2 0.8 2 21 582 601 581 602 0.94
10 17 0.0042 0.3 11.7 2.0 1 23 656 679 656 679 0.96
11 17 0.035 2.5 8.8 0.3 3 23 718 739 716 739 0.94
12 17 0.00036 0.026 15.0 1.0 2 23 780 802 779 802 0.95
13 17 0.00086 0.061 13.8 0.3 1 23 816 838 816 838 0.95
14 17 0.00013 0.0095 16.4 1.6 1 23 844 866 844 866 0.99
15 17 2.5e-07 1.7e-05 25.0 2.4 1 23 872 894 872 894 0.98
16 17 1.2e-05 0.00082 19.7 3.8 1 23 900 922 900 922 0.97
17 17 0.0022 0.15 12.6 0.2 1 23 928 952 928 952 0.90

Sequence Information

Coding Sequence
ATGAAGCTACCCGTCATGTGTCGCACATGTGATGCTAGAGACACGGATAAACTATACAAGCTGGCTACATCTACCAAACGATTTCCAGATAAACAGCTCTCCGACATTTTAGCTGAACTAACGCACATTGAATTAGATGATCCTTTGgcgcaacagctgccacaggCTCTCTGCGGTAATTGTGCCAGAAAGCTAATTGGCGCCTATTATTATGTTAAGCAGGCGCTGGCAGCAAATGAGCTCCTCATGAATCATGTGGACCGCCTGGGGAGCAGTAAAGCAACAGTCAATGACTGCCTGCAGGAGGCGCCCATGGAGCTGTGTGCCGAGCAACATGTGGAGaTCAAAATGGAAacagaggaggaggaggctgAAAATGATATAACCTGCACGGAACTGCCGGAGTTCACAACAGTACAAAATGCCAATGATGTGGACGTGGAGTTGGATAACAAGAAGTCCAATGATCCCCTCAACATGCTCGAGCCAGTGAAACTGGAGGTGGAGTCAGCCGCTGGCCGGATACCAAATTTACAAGAGCCGCAAGAATATAAGGCTGATATTGAAGATGAAGAATCCCTAGATGATTTGCCTTTGCAACAGCGCGCACACAGGTGGAAGCAAACTGGAACAATTCACGCTGTAAAACGTTCCATTTTCAAATGCACCGAATGCCCCAAGATCTTCAAACGACCGGAATATCTCAAGCAACATGCAACACGGGCGCACAAATCGAAGACCGATTGGTTTTCCTGCTCTTATTGCATACGCAAGTTCAGTCATCGAGAGGCGCTGCAGTCGCATCTAAAGGTGCATCGAGATTCAAAGCGGTCGGCGAATCTGGGCGAGAGCAAAAAGGCCAAGGATATAGATTTAAACATGTGCAAGCCGCATGGCTATAAGATAATCGAGTGTATGATTTGTCAGAGTCAATACGATAAGATAGCGGATCTTCGACGTCATCTGGAGCAGCATCCGGATATTGTAGGATTCGGTGCACGCTCCAATATGCAGCCGCACGAGGTGGCCGAGCTCTTTTACCCAGATGCCAAGCATATCAGCGTGGAGCAGCTAAAGGAGCTCATACGCAAAGATCTGGATGCCGGCATTTATCAACGTTTCTATTCCATTACTAATCAGTCGGGATATGAAATGGATCTGGACAGCTCCGAGACGGAAAGCGAGGCTGAACGGGATGTTgacgagcagcagctgaagcgcAACATACCCAAAGCCAAGTACAGCTGTGAGCTGTGCCACGAGCGCTGCCAACGCAAATACCAGCTCTTTGACCATCAACGTCTGGCCCATGCCTGGCTGGATGCGCCGCACGTCTGCGGACGCTGCGATGCGCGTTTTGTTAGCCTCCAGCTGCTAAGGCAACACAACGAGCTGCAATGCAAGAATGCCCAAAAACGTTTCCTCTGCCACAGATGTCCGCTACGCTTCCGTTGGCGTCACAATCTAAAAGCGCATATACGCGAACATCGCATTATCAATCAAACCTATGAGTGCAACGACTGCAAGCGTGTATTTGACAAAAAGAAATCCCTCACCGTACACATGCTCAGCGTGCATGCGGAGCAATCAAAACTCATACCGTGCCAATGGTGTACCCGCAAATTCTATCGACGTGACTATTTGGTGAAGCATCTGAAGCGTCATGGTATACGACAACAGGATATACCGCTCGCCGAGACGCTGATTGCGGCCACCTCAAAACCAAATGGCGTTAAGCGCATCACCTGCAAGATTTGTAATCTTCACTTTGAACGCATCTGTGACCTGCGCGCGCATattcagctggagctgaagctggccTTGTCGCTGCACCAGAACTACGATTCGCCGCACAACTACTCGATTACCAATGAGTCTGGGTACGAGCTGCAGCTAGGCGACTCGGAAACGGAGGACGaactgcaaatgcagcagccgAGAGGCTCGCCCAGCACGCGACTCGTCTACGTATGCGAGCTGTGCAAAGTGCAATGCAAGCGCAAATACGAGATGATCCAGCATCAGCGTGCGATGCATCGGTTCGACAAAATGCCACACGAGTGCGAGCTCTGCATattcaagtgtgtgtgcaagAGCATCATGGATCAACACAGAAAGTCTCAGTGTCACAGCGCCGAGAAGAAGCTGGCGTGCAGTAAGTGCAGCTACAAATTCATGTGGGCAGAGAatctgcagcagcacatgCTGCTGCAACACGGCAGCATCGATCCACAGTCTAATCCGGCAGCTGCTCTTAGCAGCGATGTAATCAGCTCTGACCGTTTGTCCGCTGTAGCGGCTAATCCTGCTATTGCGGCCGAGGAtgtacagctgctgcagtgtcCGCACTGCGATCGCACGTATCAGATGAAGGCGCGTCTCAACAATCACATACGCGACGTGCACATCAATGGGGACCGGAAGCGTAAGGAGGCCATCAAGAAGTTTCTCTGTTCGCTTTGCGGTCGGGAGACCCAGTCGGCGGCTACATTGGTCACCCATATGCGTCGGCATACGGGCGAGAAGCCGTTCAAATGTGATCTGTGTGAAATGGCCTTTCCGCGGCATTCCGAGATGATGTCCCATCGGCGAATGCACACGGGCGAGAAGCCCTACCATTGCACGGTCTGCGGCAAGGATTTTGCCCGTTCAGACAAACTGAAGCGGCACATGTTGACGCACAGCGGATTGAAGCCACACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCGAAGGATCTGAAGCTtcatctgcagcagcacacGGGCGAGTGCCCTTTCATATGTGGTACTTGTGGCGAGCGTTTCATACAGGGCACCGCCTTGGAGAAGCATCGCATGATGCGGCGTCACTTTGACGAGGTGGAGGAgcgcaccaccaccaacaacagccacacagCAACCGCTTAG
Protein Sequence
MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHIELDDPLAQQLPQALCGNCARKLIGAYYYVKQALAANELLMNHVDRLGSSKATVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTVQNANDVDVELDNKKSNDPLNMLEPVKLEVESAAGRIPNLQEPQEYKADIEDEESLDDLPLQQRAHRWKQTGTIHAVKRSIFKCTECPKIFKRPEYLKQHATRAHKSKTDWFSCSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDLNMCKPHGYKIIECMICQSQYDKIADLRRHLEQHPDIVGFGARSNMQPHEVAELFYPDAKHISVEQLKELIRKDLDAGIYQRFYSITNQSGYEMDLDSSETESEAERDVDEQQLKRNIPKAKYSCELCHERCQRKYQLFDHQRLAHAWLDAPHVCGRCDARFVSLQLLRQHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRIINQTYECNDCKRVFDKKKSLTVHMLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIRQQDIPLAETLIAATSKPNGVKRITCKICNLHFERICDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDELQMQQPRGSPSTRLVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRKSQCHSAEKKLACSKCSYKFMWAENLQQHMLLQHGSIDPQSNPAAALSSDVISSDRLSAVAANPAIAAEDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPYHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERTTTNNSHTATA