Basic Information

Insect: Drosophila tanythrix
Gene Symbol: -
Assembly: GCA_035043275.1
Location: JAWNNC010000522.1:4894323-4897510[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.9e-05 0.0021 18.6 0.9 1 23 203 226 203 226 0.96

2 17 0.013 0.9 10.3 2.2 2 23 234 255 233 255 0.96

3 17 0.39 27 5.6 0.1 2 23 287 308 286 308 0.94

4 17 0.018 1.2 9.8 6.2 1 23 399 422 399 422 0.97

5 17 0.082 5.7 7.7 0.5 1 19 429 447 429 449 0.94

6 17 0.0077 0.54 11.0 4.0 1 23 459 481 459 481 0.95

7 17 3.1e-06 0.00022 21.6 0.9 1 23 488 511 488 511 0.97

8 17 9.6e-05 0.0067 17.0 1.2 2 23 519 540 518 540 0.96

9 17 0.00074 0.052 14.2 0.3 2 21 567 586 566 587 0.94

10 17 0.025 1.7 9.4 2.2 1 23 641 664 641 664 0.96

11 17 1.5 1.1e+02 3.8 1.9 2 23 702 724 701 724 0.91

12 17 0.00015 0.01 16.4 1.6 2 23 760 782 759 782 0.95

13 17 0.00091 0.064 13.9 0.3 1 23 796 818 796 818 0.95

14 17 0.00012 0.0083 16.7 1.2 1 23 824 846 824 846 0.99

15 17 3.8e-07 2.6e-05 24.5 2.6 1 23 852 874 852 874 0.98

16 17 1.7e-06 0.00012 22.4 2.2 1 23 880 902 880 902 0.98

17 17 0.0013 0.091 13.4 0.2 1 23 908 932 908 932 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.9e-05	0.0021	18.6	0.9	1	23	203	226	203	226	0.96
2	17	0.013	0.9	10.3	2.2	2	23	234	255	233	255	0.96
3	17	0.39	27	5.6	0.1	2	23	287	308	286	308	0.94
4	17	0.018	1.2	9.8	6.2	1	23	399	422	399	422	0.97
5	17	0.082	5.7	7.7	0.5	1	19	429	447	429	449	0.94
6	17	0.0077	0.54	11.0	4.0	1	23	459	481	459	481	0.95
7	17	3.1e-06	0.00022	21.6	0.9	1	23	488	511	488	511	0.97
8	17	9.6e-05	0.0067	17.0	1.2	2	23	519	540	518	540	0.96
9	17	0.00074	0.052	14.2	0.3	2	21	567	586	566	587	0.94
10	17	0.025	1.7	9.4	2.2	1	23	641	664	641	664	0.96
11	17	1.5	1.1e+02	3.8	1.9	2	23	702	724	701	724	0.91
12	17	0.00015	0.01	16.4	1.6	2	23	760	782	759	782	0.95
13	17	0.00091	0.064	13.9	0.3	1	23	796	818	796	818	0.95
14	17	0.00012	0.0083	16.7	1.2	1	23	824	846	824	846	0.99
15	17	3.8e-07	2.6e-05	24.5	2.6	1	23	852	874	852	874	0.98
16	17	1.7e-06	0.00012	22.4	2.2	1	23	880	902	880	902	0.98
17	17	0.0013	0.091	13.4	0.2	1	23	908	932	908	932	0.91

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTCATGTGTCGCACTTGCGATGCACGAGAAACGGACAAACTATACAAACTGGCAACGTCCACCAAAAGATTTCCGAATAAACAGCTTGCCGACATTTTGGTCGAATTGACACACATCGATCTTGATGAGGCATTGTCgcaacagctgccacaatGTCTGTGCGGCAATTGTGCCCGCAAGTTAATCAGCGCCTATTACTACGTGAAGCAGGCGCTGGCCGCCAGCGAGCTGCTGATGCACCATGCGCCCATGGAGATGTGCGCCGAGCAGCATGTGGAGGTCAAATTGGAaacggaggaggaggatgctGAGAATGATATCACCTGCACAGAACTGCCCGAGTTTACCACAGTACAAAATGCAATCGATGTGGAATTGGATGATGAGTTGGATGGCAAAAAGTCGGCAGATCCACTGAATATGCTCGAACCAGTTAAACAGGAAGAGGATGCTGCAGCTGGAGCAACAAATGCACAGGCACAAGAACTTAAGGCTGACCTAGATGAGGAAGACTCTCTGGATGATTTGCCATTGCAAGAGCGCGCCAGGAAATGGAAACAGACGGCTAAGTTGCACACTCTCAAACGAGCCATCTTCAAGTGCAAGGAATGCCCAAAGAACTTCAAGCGCATCGAGCTATTGAAGCAGCATGCATCCCGTGCGCACAAGTCGAAGACGGATTGGTTGTCGTGCTCGTTTTGCATACGCAAGTTTAGTCATCGGGAAGCGCTGCAGATGCATCTCAAAGTACATCGCGACTCCAAGCGCTCCGCGAATCTGGGCGAGAGCAAAAAGGCCAAGGACATCGATGTGAACGTGTGCAAGCCGCATGGCTACAAGCTTATCGAGTGCATGATCTGTCAGAGTCAATACGATAAGATTGCGGACCTGCGACGACATCTGGAGCAGCATCCGGAAATTGTTGGCTTTGGGGCACGCTCGAATATGCAGCCGCATGAATTGGCCGAGCTCTTTTATCCAGATGCCAAGGATGTTAGCGAGGATCAGTTGAAGGCGCTAATACGCAAAGATCTTTCCGCTGGGATCTATCAACGTTTCTACTCGATAACCAATCAATCTGGCTACGAAATGGATCTCTACAGCTCCGAGACGGAGAGCGAGGCTGAACTGGATGCCGAGGAGCGAGAAGCGAATCAACAGCGCAGCATACCCAAAGCCAAATATAGTTGTGAGTTGTGTCACGAGCGCTGCCAGCGCAAATATCAGCTGTACGATCATCAGCGCCAGATGCACGCATGGCTGGAGGCGCCACACGTCTGTGGCCGTTGCGATGCTCGCTTCGTCagcctgcagctgctgcggcatCACAACGAGCTGCAGTGCAAGAATGCCCAGAAGCGCTTCCTATGCCACAGATGTCCATTGCGATTCCGCTGGCGGCACAATCTCAAGGCTCACATACGCGAGCATCGCATCACAAATCAAACATTCGAGTGCAACGACTGCAAGCGTGTCTTTGACAAGAAGAAGTCGCTGACGGTACATATGCTCAGTGTGCATGCCGAGGAATCTAAATTGATACCCTGCCAATGGTGCACACGCAAATTCTATCGTCGCGATTACCTGGTCAAGCATTTGAAGCGTCATGGGATACGGGAGCAGGATATACCGCTGGCGGAGACACTCATTGCGGCCACATCGAAACCGAATGGCGCCAAACGGATCACGTGCAAAATATGCAATCTGCACTTTGAGCGCATCAGCGATCTGCGCTCGCACATTCAGCTGGAACTGAAGTTGGCCCTCTCCATGCATCAGAACTATGATTCGCCGCACAACTACTCGATCACAAACGAATCGGGGTATGAACTGCAGCTGGGCGACTCTGAAACGGAGGATGAGTTGCATATGCAGTCGGCATCCTCGCCTCCAAGTGCACGCTCCGTCTACATCTGTGAACTGTGCAAAGTGCAATGCAAACGCAAATTCGAAATGATTCAGCATCAGCGTGCCATGCATCGCTTCGACAAGATGCCTTACGAGTGTGAACTGTGCATCTTCAAGTGCGTCTGCATGAGCATCATGGAGCAGCACCGGCAATCGCAGTGCCACAGCACGGCAAAGCAGTTGTCGTGTTGCAAATGCAGTTACAAATTCTTGTGGCCAGAGAATCTGCAACAACAcatgcagctgcaacatgGCAGCATCGCTGACAGCACCAGCCCAGTGGAACCAGGCGCAACTAGCGCCAATCACATTCCAGCCATTCCAGTGGATCCTCCAGCGGATAgtgtgcagctgttgcagtgTCCGCACTGCGATCGCACGTATCAAATGAAGTCGCGGCTCAACAATCACATACGGGACGTGCACATCAATGGGGATCGCAAGCGGAAGGAGGCCATCAAGAAGTTCCTGTGCTCGCTGTGCGGCCGGGAAACGCAATCCGCTGCCACATTAGTCACGCATATGCGTCGCCACACCGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAAATGGCCTTTCCACGGCACTCGGAAATGATATCGCATCGACGGATGCATACGGGTGAGAAACCCTTCCATTGCACCGTCTGCGGCAAGGATTTCGCACGCTCCGACAAGCTGAAGCGGCACATGCTGACGCACAGTGGGCTGAAGCCATACAAGTGCACCTACTGCGACAAAAGCTATCGCCAGGCCAAGGATCTGAAACTGCATCTCCAGCAGCACACCGGCGAGTGCACATTCGTCTGCGGCACCTGCGGCGAACGCTTCATTCAGGGCACAGCGCTGGAGAAGCATCGCATGATGCGGCGCCATTTCGACGAGGTCGAGGAGCGTGCCACAAGCACTTTAACTGCATAG
Protein Sequence: MKLPVMCRTCDARETDKLYKLATSTKRFPNKQLADILVELTHIDLDEALSQQLPQCLCGNCARKLISAYYYVKQALAASELLMHHAPMEMCAEQHVEVKLETEEEDAENDITCTELPEFTTVQNAIDVELDDELDGKKSADPLNMLEPVKQEEDAAAGATNAQAQELKADLDEEDSLDDLPLQERARKWKQTAKLHTLKRAIFKCKECPKNFKRIELLKQHASRAHKSKTDWLSCSFCIRKFSHREALQMHLKVHRDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIADLRRHLEQHPEIVGFGARSNMQPHELAELFYPDAKDVSEDQLKALIRKDLSAGIYQRFYSITNQSGYEMDLYSSETESEAELDAEEREANQQRSIPKAKYSCELCHERCQRKYQLYDHQRQMHAWLEAPHVCGRCDARFVSLQLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTFECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICNLHFERISDLRSHIQLELKLALSMHQNYDSPHNYSITNESGYELQLGDSETEDELHMQSASSPPSARSVYICELCKVQCKRKFEMIQHQRAMHRFDKMPYECELCIFKCVCMSIMEQHRQSQCHSTAKQLSCCKCSYKFLWPENLQQHMQLQHGSIADSTSPVEPGATSANHIPAIPVDPPADSVQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPYKCTYCDKSYRQAKDLKLHLQQHTGECTFVCGTCGERFIQGTALEKHRMMRRHFDEVEERATSTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00495265;
80% Identity: -