Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000048.1:1425971-1429151[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.5e-06 0.00029 21.0 1.7 1 23 242 265 242 265 0.94

2 17 0.0076 0.49 10.9 4.2 1 23 272 294 272 294 0.98

3 17 0.4 26 5.5 0.7 2 23 326 347 325 347 0.94

4 17 0.009 0.58 10.6 4.7 1 23 437 460 437 460 0.96

5 17 0.068 4.4 7.9 0.5 1 19 467 485 467 488 0.93

6 17 0.0042 0.27 11.7 4.3 1 23 497 519 497 519 0.95

7 17 5.2e-05 0.0034 17.7 0.5 1 23 526 549 526 549 0.96

8 17 9.3e-05 0.006 16.9 1.2 2 23 557 578 556 578 0.96

9 17 0.0037 0.24 11.9 0.1 2 21 605 624 604 625 0.94

10 17 0.0043 0.28 11.7 2.0 1 23 678 701 678 701 0.96

11 17 0.0033 0.21 12.0 0.4 1 23 738 761 738 761 0.95

12 17 0.00014 0.0091 16.3 1.6 2 23 790 812 789 812 0.95

13 17 0.00088 0.057 13.8 0.3 1 23 826 848 826 848 0.95

14 17 0.00011 0.0074 16.6 1.2 1 23 854 876 854 876 0.99

15 17 3.6e-07 2.4e-05 24.5 2.6 1 23 882 904 882 904 0.98

16 17 1.2e-05 0.00077 19.7 3.8 1 23 910 932 910 932 0.97

17 17 0.0022 0.14 12.6 0.2 1 23 938 962 938 962 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.5e-06	0.00029	21.0	1.7	1	23	242	265	242	265	0.94
2	17	0.0076	0.49	10.9	4.2	1	23	272	294	272	294	0.98
3	17	0.4	26	5.5	0.7	2	23	326	347	325	347	0.94
4	17	0.009	0.58	10.6	4.7	1	23	437	460	437	460	0.96
5	17	0.068	4.4	7.9	0.5	1	19	467	485	467	488	0.93
6	17	0.0042	0.27	11.7	4.3	1	23	497	519	497	519	0.95
7	17	5.2e-05	0.0034	17.7	0.5	1	23	526	549	526	549	0.96
8	17	9.3e-05	0.006	16.9	1.2	2	23	557	578	556	578	0.96
9	17	0.0037	0.24	11.9	0.1	2	21	605	624	604	625	0.94
10	17	0.0043	0.28	11.7	2.0	1	23	678	701	678	701	0.96
11	17	0.0033	0.21	12.0	0.4	1	23	738	761	738	761	0.95
12	17	0.00014	0.0091	16.3	1.6	2	23	790	812	789	812	0.95
13	17	0.00088	0.057	13.8	0.3	1	23	826	848	826	848	0.95
14	17	0.00011	0.0074	16.6	1.2	1	23	854	876	854	876	0.99
15	17	3.6e-07	2.4e-05	24.5	2.6	1	23	882	904	882	904	0.98
16	17	1.2e-05	0.00077	19.7	3.8	1	23	910	932	910	932	0.97
17	17	0.0022	0.14	12.6	0.2	1	23	938	962	938	962	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCAGTCATGTGCCGTACTTGCGACGCAAGGGACACCGATAAACTGTATAAGTTAGCGACGGCAACCAAAAGATTCCCGGATAAATTGCTCTCCGACATTTTAGCTGAATTGACGCACATTGAGGTAGATGATCCATTGGCACAGCGACTCCCACAATGTTTGTGCGGCACCTGCGCCAGAAAACTAATAAGCGCCTATTACTATGTAAAGCAGGCGCTGGCAGCAAATGAGCTGCTGATAAACCACGTGCAGGATACTGACAAGGCCACTGTGGTGGACTGTCTGCAGGAAGTACCCATGGAACTGTGTGCCGAACAACATGTAGAGGCAAGtcttgtttattgttattacttgAATCTCTCACAAAACAATTGTCTGAAGGTTAAATTGGAAACGGAAGAAGAGGATGTTGACAACGATATCACCTGCACAGAACTGCCGGAATTCACTACAGTGCAAAATGCCAACGATGCTGACAACACATTGAGCAGTGATGTGGATGTGACCAAAGCGTCCAACGATCCATTGACAATGGTTGATCCCGTCAAACAGGAAGAGGATGGAgttgcaacaaaagcaacgatTGCCCAGGAGCACTTGTACAAGGCTGATAATGATAACGACGAAGAAGATTCGCTGGATGATTTGCCTCTACAACAGCGGGTACAAAAGTGGaggcaaacagaaaaacaTCGCAGATTAAAGAGGCAAATATTCGAGTGCAAAGAATGTCCCAAGAGCTTCAAGCGCCCCAGATATCTAAAGCAGCATTCTTCGCGAGtgcataaattgaaaactgatTTGTATTCCTGCTCGTTCTGCATAAGAAAGTTCAGTCACCACGAAGCTCTGAAAGCACATCTCAAGGTGCACGGGGATTCGAAGAGATCGGCCAATTTGggagaaaataaaaaggcCAAGGATATTGATGTAAATGTGTGCAAACCTCACGGCTACAAGCTTATTGAGTGCATGATATGCCAAAGTCAATACGATAAAATCGTTCATTTGCGACGCCACTTGGAGCAGCATCCAGAGATTCTTAACTTTGGCACACGATCCAATATGGAACCCAATGAACTTGCCGAGCTGTTCTATCCAGATGCCAAGGATATCAGTGAGCAAGAATTAAAGGCGCTCATACGAAAAGATTTAGATGCTGGCATTTATCAACGTTTCTATTCGATAACGAATCAATCGGGCTATGAAATAGATCTAGACAGTTCCGAGACTGATAGTGAAGCTGAACTGGATGCTGATGAGCATGCGAAGCAACAACGAAGCATACCAATAGCCAAATACTGTTGTGAACTTTGCCAGGAACGCTATCAACGGAAGTATCAGCTGTACGAGCATCAGCGTCAAACGCATCTCTGGCAGGATGCACCGCATGTTTGTGGTCGTTGTGATGCTCGCTTTGTTAGCCTGCAGTTGCTGCGGCATCACAACGAGTCGCAATGCAAAAATTCCCAAAAACGTTTTCTATGCCACAAATGTCCATTGCGCTTTCGCTGGCGTCACAATCTAAAGGTGCACATCAGGGAGCACAGAATTACCAATCAAACATTCGAGTGCGTCGATTGCAAACGAGTCTTTGACAAGAAGAAGTCGCTGACAGTTCATTTGCTGAGCGTGCATGCAGAGCAATCGAAGCTGATACCGTGCCAATGGTGCACTCGCAAATTCTACCGACGCGACTATCTGGTGAAGCACCTCAAGAGACATGGCATTCGAGAGCAGGATATTCCATTGGCGGAAACACTTATTGCGGCCACTTCAAAGCCGAATGGCAACAAACGAATAACCTGCAAGATCTGCAACATGCACTTTGAGCGTATCATTGATTTGCGTGCTCACATTCAGCTGGAGCTAAAGCTGGCTCTGTCGCTGCACCAGAACTATGATTCGCCACACAACTACTCGATAACAAATGAATCGGGATACGAGCTACAGCTAGGCGACTCTGAGACAGAGGACGaagtgcaaatgcaaatgcagatgCAATCAACGTCGCGCATCGCCTACGTCTGTGAGCTGTGCAAAGTGCAATGCAAACGAAAGTACGAGATGATACAGCATCAGCGTGCCATGCATCGTTTTGACAAGATGCCACATGAGTGTGGGACCTGCATTTTCAAGTGTGTCTGCAAGAGCATTATGGATCAGCATCGTCAATCGCAGTGCCACAGCACTGAAAAGAAATACGCGTGCGGTAGATGTGGCTACAAGTTTATGTGGTCTGAGAATCTTCAGCAGCATATGCAACTCCAACATGGTGGCAATGAACGTGGTGCTAGCGCTGATCGTCTTCTACCCAATGATGCAGCGGATCAAGTCGATCCAGCTCTTCAATTACTACAATGTCCCCACTGCGATCGCACCTATCAAATGAAATCACGCCTTAACAATCACATACGGGACGTGCACATCAACGGGGATCGCAAACGCAAGGAAGCCATCAAAAAGTTCTTGTGCTCGCTATGTGGTCGCGAGACGCAATCCGCAGCAACCTTGGTAACCCACATGCGTCGCCATACAGGCGAGAAACCATTCAAATGTGATTTATGTGAAATGGCCTTTCCACGACACTCGGAAATGATATCGCATCGACGCATGCACACCGGCGAGAAACCATTCCATTGTACAGTCTGCGGCAAGGATTTCGCCCGATCCGATAAGCTCAAGCGACACATGCTCACCCACAGCGGACTGAAGCCCCATAAGTGCACGTACTGCGACAAGAGCTATCGCCAGGCCAAGGATTTAAAGCTACATCTTCAGCAGCACACGGGCGAGTGCCCCTTCATCTGTGGTACATGCGGCGAACGCTTCATCCAAGGCACCGCGCTCGAAAAGCATCGAATGATGCGTCGTCACTTTGACGAAGTCGACGAACGAGGTACAACGCAATCGCAGATGCAGCCACAAACCGCTTAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILAELTHIEVDDPLAQRLPQCLCGTCARKLISAYYYVKQALAANELLINHVQDTDKATVVDCLQEVPMELCAEQHVEASLVYCYYLNLSQNNCLKVKLETEEEDVDNDITCTELPEFTTVQNANDADNTLSSDVDVTKASNDPLTMVDPVKQEEDGVATKATIAQEHLYKADNDNDEEDSLDDLPLQQRVQKWRQTEKHRRLKRQIFECKECPKSFKRPRYLKQHSSRVHKLKTDLYSCSFCIRKFSHHEALKAHLKVHGDSKRSANLGENKKAKDIDVNVCKPHGYKLIECMICQSQYDKIVHLRRHLEQHPEILNFGTRSNMEPNELAELFYPDAKDISEQELKALIRKDLDAGIYQRFYSITNQSGYEIDLDSSETDSEAELDADEHAKQQRSIPIAKYCCELCQERYQRKYQLYEHQRQTHLWQDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRITNQTFECVDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGNKRITCKICNMHFERIIDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEVQMQMQMQSTSRIAYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECGTCIFKCVCKSIMDQHRQSQCHSTEKKYACGRCGYKFMWSENLQQHMQLQHGGNERGASADRLLPNDAADQVDPALQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGTTQSQMQPQTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00472485; iTF_00556639; iTF_00553834;
80% Identity: -