Basic Information

Insect: Drosophila testacea
Gene Symbol: -
Assembly: GCA_035043265.1
Location: JAWNND010001120.1:1329868-1333100[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.018 1.4 9.7 0.0 1 23 220 241 220 241 0.97

2 16 0.23 18 6.3 0.7 2 23 273 294 272 294 0.94

3 16 0.0083 0.63 10.8 4.2 1 23 384 407 384 407 0.97

4 16 0.058 4.4 8.2 0.5 1 19 414 432 414 435 0.92

5 16 0.032 2.4 9.0 5.1 1 23 444 466 444 466 0.95

6 16 0.0012 0.093 13.5 0.5 1 23 473 496 473 496 0.94

7 16 9.2e-05 0.007 17.0 1.2 2 23 504 525 503 525 0.96

8 16 0.0036 0.28 12.0 0.1 2 21 552 571 551 572 0.94

9 16 0.0074 0.56 11.0 1.9 1 23 625 648 625 648 0.96

10 16 0.014 1.1 10.1 0.5 1 23 685 708 685 708 0.95

11 16 0.00014 0.011 16.4 1.6 2 23 739 761 738 761 0.95

12 16 0.00087 0.066 13.9 0.3 1 23 775 797 775 797 0.95

13 16 0.00011 0.0086 16.7 1.2 1 23 803 825 803 825 0.99

14 16 3.6e-07 2.7e-05 24.6 2.6 1 23 831 853 831 853 0.98

15 16 1.2e-05 0.00089 19.8 3.8 1 23 859 881 859 881 0.97

16 16 0.0022 0.17 12.7 0.2 1 23 887 911 887 911 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.018	1.4	9.7	0.0	1	23	220	241	220	241	0.97
2	16	0.23	18	6.3	0.7	2	23	273	294	272	294	0.94
3	16	0.0083	0.63	10.8	4.2	1	23	384	407	384	407	0.97
4	16	0.058	4.4	8.2	0.5	1	19	414	432	414	435	0.92
5	16	0.032	2.4	9.0	5.1	1	23	444	466	444	466	0.95
6	16	0.0012	0.093	13.5	0.5	1	23	473	496	473	496	0.94
7	16	9.2e-05	0.007	17.0	1.2	2	23	504	525	503	525	0.96
8	16	0.0036	0.28	12.0	0.1	2	21	552	571	551	572	0.94
9	16	0.0074	0.56	11.0	1.9	1	23	625	648	625	648	0.96
10	16	0.014	1.1	10.1	0.5	1	23	685	708	685	708	0.95
11	16	0.00014	0.011	16.4	1.6	2	23	739	761	738	761	0.95
12	16	0.00087	0.066	13.9	0.3	1	23	775	797	775	797	0.95
13	16	0.00011	0.0086	16.7	1.2	1	23	803	825	803	825	0.99
14	16	3.6e-07	2.7e-05	24.6	2.6	1	23	831	853	831	853	0.98
15	16	1.2e-05	0.00089	19.8	3.8	1	23	859	881	859	881	0.97
16	16	0.0022	0.17	12.7	0.2	1	23	887	911	887	911	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGCCGCACTTGCGATGCAAGAGACACAGATAAACTGTATAAGTTGGCGACGGCCACCAAAAGGTTCCCGGATAAGCTGCTCTCCGACATTTTAGCTGAATTGACGCACATCGATGTAAACGGTTCATTGGCCCAACGGCTACCTCAGTGTCTGTGCGGCACCTGCGCAAGAAAACTAATTGGAGCCTATTACTATGTAAAACAGGCTGTGGCAGCCAATGAACTGTTGATGAACCATGTCCAAAACAGTGACAAAGCGGTGACCAGTGACTGCCTACAGGAAGTGCCAATGGAACTCTGTGCCGAGCAGCATGTTGAGGTTAAACTGGAAACAGAGGaagatgaaattgaaaacgatATAACCTGCACAGAACTGCCCGAGTTCACTACAGTACAAAATGCCAATGATGTTATCGAGAACACACTGGAATGTGATCTGGACAACAAGAAATCTACAGATCCATTGCTTGATCCCGTCAAACAGGAAGAGGATAGCTTTGCAACGAGAGCAGCGATTATCCGTGAGCATAAATATAAGGCTGATAATGATGAAGAAGATTCACTCGATGATTTGCCTTTACAACAACGTGTGCACAAATggaaacagacggacaaactGCGTGGTCTTAAAAGACAGATATTCGCGTGCAAGGAATGTCCAAAAGCTTTAAACGCCCTAGCGCTACAGGCGCATCTAAAGGTGCACGCAGACTCCAAGCGATCTGCCAATTTGGGCGAGAGTAAAAAGGCCAAGGATATtgatgtgaatgtgtgtaagCCACATGGCTACAAGCTCATCGAGTGCATGATCTGCCAGAGTCAATACGATAAGATTGCCCATCTGAGACGGCACCTAGAACAGCATCCTGAAATTGTTAACTTTGGTACGCGATCAAATATGCAACCAAATGAGTTGGCCGAACTGTTTTATCCCGATGCCAAGGATGTGAGCATGGATCAATTAAAGGAACTCATTCGTAAAGATTTGGCAACAGGTATTTACCAGCGTTTCTACTCGATAACAAACCAGTCGGGCTATGAAATGGATCTGGACACCTCCGAAACAGAAAGCGAGGCCGAACTAGATGGCGATGAACAGTCAAGACAACACCGCAGCATACCCAAAGCCAAATACAGCTGCGAACTGTGCCAGGAGCGTTGTCAACGCAAGTATCAGCTGTACGAACACCAGCGTCAGTCGCATGCCTGGCTGGATGCACCTCATGTATGTGGTCGTTGTGATGCTCGCTTTGTTAGCCTCCAGCTTCTGAGGCACCACAATGAGACGCAGTGTAAGAATTCCCAAAAACGTTTCCTGTGCCACAAATGCCCGTTACGCTTCCGCTGGCGGCATAACCTAAAGGTTCACACAAGGGATCATAGAATAACCAATCAAACATTTGAGTGTATCGATTGTAAACGCGTCTTTGACAAAAAGAAATCGCTGACAGTCCATTTGCTGAGTGCACATGCGGAGGAATCAAAGCTGATACCGTGTCAATGGTGTACTCGCAAGTTCTATCGACGGGACTATTTGGTGAAGCATCTGAAGCGACATGGAATTAGGGAGCAAGATATTCCGCTTGCCGAGACACTTATTGCGGCCACATCAAAGCCAAATGGTGCCAAACGGATTACCTGCAAGATCTGCAATATGCATTTTGAGCGTATCATCGACCTACGGGCTCATATTCAGCTGGAACTGAAGCTAGCGCTGTCACTGCACCAAAACTATGATTCACCGCATAACTACTCCATAACAAATGAATCCGGTTATGAGTTGCAGCTTGGCGACTCCGAGACGGAAGATGAAATGCAGATGCAGTCAACTCCAGCGTCAACTCCACGTCTTGTTTACATCTGCGAGCTGTGCAAAGTGCAATGTAGGCGAAAGTATGAGATGATACAGCATCAGCGTGCCATGCATCGGTTTGATAAGATGCCACACGAGTGCGAAATctgcatatttaaatgtgtcTGCAAGAGCATAATGGATCAGCATAGGCAATCGCAGTGTCACAGCGCGGAGAAGAAATATGCTTGCAGCAGATGCAGCTATAAGTTTATGTGGCCCGAGAATCTGCAGCAACatatgcaactgcaacacggCGGCATGCTGCGAGCCCCAAGTGCTGATCGTATACCAGATCCTGCTGATCCTGCCATTGATCCAGTAGATCCGGCCTTACAGCTACTGCAATGCCCGCACTGCGATCGCACCTATCAAATGAAATCACGACTGAACAATCACATACGGGATGTGCATATCAATGGGGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTCCTATGCTCGCTGTGTGGCCGCGAAACCCAATCGGCGGCCACTTTGGTTACCCACATGCGTCGTCACACGGGCGAAAAACCCTTCAAATGCGATCTGTGTGAAATGGCATTTCCACGGCACTCGGAAATGATATCGCATCGCAGAATGCACACAGGAGAGAAACCATTCCATTGCACAGTCTGTGGCAAGGACTTTGCCCGCTCTGACAAACTGAAGCGACATATGCTCACCCACAGCGGTCTGAAGCCGCACAAGTGTACATACTGCGATAAGAGCTATCGTCAGGCCAAGGATCTAAAGTTACACTTGCAACAGCACACCGGCGAGTGCCCCTTCATATGTGGCACATGTGGGGAGCGATTTATTCAGGGCACAGCGCTGGAGAAGCATCGTATGATGAGGCGTCATTTTGACGAGGTGGATGAACGCGTCTCAACTCAAACATTAACCGCATAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILAELTHIDVNGSLAQRLPQCLCGTCARKLIGAYYYVKQAVAANELLMNHVQNSDKAVTSDCLQEVPMELCAEQHVEVKLETEEDEIENDITCTELPEFTTVQNANDVIENTLECDLDNKKSTDPLLDPVKQEEDSFATRAAIIREHKYKADNDEEDSLDDLPLQQRVHKWKQTDKLRGLKRQIFACKECPKALNALALQAHLKVHADSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIAHLRRHLEQHPEIVNFGTRSNMQPNELAELFYPDAKDVSMDQLKELIRKDLATGIYQRFYSITNQSGYEMDLDTSETESEAELDGDEQSRQHRSIPKAKYSCELCQERCQRKYQLYEHQRQSHAWLDAPHVCGRCDARFVSLQLLRHHNETQCKNSQKRFLCHKCPLRFRWRHNLKVHTRDHRITNQTFECIDCKRVFDKKKSLTVHLLSAHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICNMHFERIIDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQMQSTPASTPRLVYICELCKVQCRRKYEMIQHQRAMHRFDKMPHECEICIFKCVCKSIMDQHRQSQCHSAEKKYACSRCSYKFMWPENLQQHMQLQHGGMLRAPSADRIPDPADPAIDPVDPALQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERVSTQTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00558065; iTF_00583843;
80% Identity: -