Basic Information

Insect: Drosophila ustulata
Gene Symbol: -
Assembly: GCA_035047365.1
Location: JAWNPT010000094.1:3466414-3469609[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.6e-06 0.00031 21.1 1.7 1 23 227 250 227 250 0.94

2 17 0.0063 0.42 11.2 3.7 1 23 257 279 257 279 0.98

3 17 0.9 61 4.4 0.2 2 23 311 332 310 332 0.94

4 17 0.0091 0.61 10.7 4.7 1 23 422 445 422 445 0.96

5 17 0.069 4.6 7.9 0.5 1 19 452 470 452 473 0.93

6 17 0.0043 0.29 11.7 4.3 1 23 482 504 482 504 0.95

7 17 5.2e-05 0.0035 17.7 0.5 1 23 511 534 511 534 0.96

8 17 9.4e-05 0.0063 16.9 1.2 2 23 542 563 541 563 0.96

9 17 0.0037 0.25 11.9 0.1 2 21 590 609 589 610 0.94

10 17 0.013 0.91 10.1 2.2 1 23 665 688 665 688 0.96

11 17 0.037 2.5 8.7 0.6 1 23 725 748 725 748 0.95

12 17 0.00014 0.0096 16.4 1.6 2 23 777 799 776 799 0.95

13 17 0.00089 0.06 13.8 0.3 1 23 813 835 813 835 0.95

14 17 0.00012 0.0078 16.6 1.2 1 23 841 863 841 863 0.99

15 17 3.7e-07 2.5e-05 24.5 2.6 1 23 869 891 869 891 0.98

16 17 1.2e-05 0.00081 19.7 3.8 1 23 897 919 897 919 0.97

17 17 0.0022 0.15 12.6 0.2 1 23 925 949 925 949 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.6e-06	0.00031	21.1	1.7	1	23	227	250	227	250	0.94
2	17	0.0063	0.42	11.2	3.7	1	23	257	279	257	279	0.98
3	17	0.9	61	4.4	0.2	2	23	311	332	310	332	0.94
4	17	0.0091	0.61	10.7	4.7	1	23	422	445	422	445	0.96
5	17	0.069	4.6	7.9	0.5	1	19	452	470	452	473	0.93
6	17	0.0043	0.29	11.7	4.3	1	23	482	504	482	504	0.95
7	17	5.2e-05	0.0035	17.7	0.5	1	23	511	534	511	534	0.96
8	17	9.4e-05	0.0063	16.9	1.2	2	23	542	563	541	563	0.96
9	17	0.0037	0.25	11.9	0.1	2	21	590	609	589	610	0.94
10	17	0.013	0.91	10.1	2.2	1	23	665	688	665	688	0.96
11	17	0.037	2.5	8.7	0.6	1	23	725	748	725	748	0.95
12	17	0.00014	0.0096	16.4	1.6	2	23	777	799	776	799	0.95
13	17	0.00089	0.06	13.8	0.3	1	23	813	835	813	835	0.95
14	17	0.00012	0.0078	16.6	1.2	1	23	841	863	841	863	0.99
15	17	3.7e-07	2.5e-05	24.5	2.6	1	23	869	891	869	891	0.98
16	17	1.2e-05	0.00081	19.7	3.8	1	23	897	919	897	919	0.97
17	17	0.0022	0.15	12.6	0.2	1	23	925	949	925	949	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGCCGCACTTGCGATGCAAGAGACACTGACAAACTTTATAAGTTGGCAACGGCCACCAAAAGGTTCCCGGACAAGTTGCTCTCCGACATTTTAGCTGAATTGACACacattaatGTGAACGATTTACTTGCGCAGCGACTGCCACAATGTCTGTGCGGCACCTGCGCAAGAAAACTGATAGGTGCTTATTACTATGTGAAGCAGGCGGTGGCAGCCAACGAGCTGCTGATGAACCATGTACACGGCAGCGAAAACAACAAAGCCGTGGCCAACGACTGCCTGCAGGAAGTTCCCATGGAGCTGTGTGCAGAGCAACATGTGGAGGTTAAATTAGAAACCGAAGAAGAGGAGGTTGACAACGATATAACGTGCACGGAACTGCCCGAGTTCACCACAGTACAAAATGCCAATGATGTGGAAAATCCAATGGGGAGTGATGTAGATGTGGATGTGGACAATAAGGCATCCAACGATCCATTGACAATGGTCGATCCAGTCAAACAGGAAGAGGATGGTGTTGCAACGAGAGCAGCGCTCGCCCAGCAGCACAAATATAAGGCTAATGATGATGAAGAAGATTCTCTGGATGATTTGCCTCTACAACTGCGTGTACAAAAATGGAAGCAGACAGAGAAGCATCGATTATTAAAGAGGCAAATATTCGAGTGCAAGGAATGTCCAAAGAGCTTTAAACGTCCCAGATATTTAAAGCAGCATTCATCGCGAGTGCACAGATCGAAAACAGATTGGTATTCGTGCTCGTTCTGCATACGAAAGTTCAGCCACCACGAAGCACTGCAGGCACATCTAAAGGTGCACGGGGATTCGAAGCGATCGGCCAATTTAGGAGAGAACAAAAAGGCCAAGGACATTGATGTGAACGTGTGCAAACCCCATGGCTATAAGCTCATTGAGTGCATGATCTGCCAGAGTCAATACGATAAGATAGTTTATTTGCGACGTCACTTGGAACAGCATCCAGACATTGTAAGCTTTGGGACACGCTCAAATATGGAACCCAATGAGCTCGCCGAACTCTTTTATCCTGATGTCAAGGACGTGAGCGTGGACGAATTGAAGGCACTCATTCGCAAAGATTTGGCTGCAGGCGTTTTTCAGCGTTTCTATTCGATAACAGATCAATCGGGTTATGAAATGGATCTAGACAGCTCCGAGACGGATAGCGACGCTGAACTGGATGGCGATGAGAACTCGAAGCAACAGCGCAGCATACCGAAATCCAAATACTGTTGTGAACTTTGCCAAGAGCGGTATCAACGCAAGTATCAGCTCTATGAGCATCAGCGGCAGACGCATCTTTGGCAGGATGCGCCTCACGTCTGTGGTCGTTGCGATGCTCGCTTTGTTAGCCTGCAATTGCTGCGACATCACAACGAGTCGCAGTGCAAGAATTCACAAAAACGCTTCCTATGCCACAAATGTCCGTTGCGCTTTCGCTGGCGTCACAATCTGAAGGTTCACATAAGGGAGCACAGGATTGCCAATCAAACATTCGAGTGCGTGGACTGCAAACGAGTCTTTGATAAGAAGAAATCGCTAACAGTTCATTTACTGAGTGTGCATGCCGAGCAATCGAAGCTTATACCATGCCAATGGTGCACTCGGAAGTTCTATCGACGAGACTACCTGGTGAAGCATCTGAAGCGACACGGCATTAGAGAGCAGGACATTCCGCTGGCGGAGACACTTATTGCGTCCACCTCAAAGCCGAATGGAGTCAAACGAATCACCTGCAAGATTTGTAACATGCACTTTGAGCGCATCATCGATCTGCGAGCTCACATTCAGCTCGAACTGAAGCTAGCATTGTCCCTCCACCAGAACTATGATTCGCCACACAACTACTCCATAACGAATGAATCAGGATACGAGCTGCAGCTTGGCGACTCTGAGACAGAGGATGAAATGCAACTTCAAATGCAATCAACGCCTACATCAACTTCGCGAATCGTCTACGTCTGTGAGTTGTGCAAAGTGCAATGCAAACGAAAGTTCGAGATGATACAGCATCAGCGTGCCATGCATCGGTTCGACAAGATGCCCCACGAGTGTGATCTCTGCATCTTCAAGTGCGTCTGCAAGAGTATCATGGATCAGCACCGTCAATCGCAGTGTCGCAACACTGAGAAGAAGTATGCATGCAGGAGATGCAGCTACAAATTTATGTGGCCGGAGAATCTGCAGCAGCatatgcaactgcaacatggGGGCATTGAGCGGGGTGCCAGCGCTGATCGTCGTCTAGCAGACTATCCTGCTGACCAGGTTGAATCAGCCTCACAATTACTGCAATGCCCGCACTGTGATCGCACCTATCAAATGAAGTCACGCCTCAACAATCACATACGGGATGTGCACATCAATGGGGATCGCAAGCGCAAGGAAGCCATCAAGAAATTCTTGTGTTCGCTGTGTGGTCGAGAGACGCAATCTGCAGCCACCTTGGTTACCCATATGCGTCGCCACACTGGTGAGAAGCCATTCAAATGTGATCTGTGTGAAATGGCCTTCCCCAGGCACTCGGAAATGATATCGCATCGTCGAATGCACACGGGCGAAAAACCATTCCATTGCACGGTGTGCGGCAAGGATTTCGCACGATCCGACAAGCTGAAGCGACACATGCTCACCCACAGCGGACTGAAGCCGCACAAGTGCACGTACTGCGATAAAAGCTATCGTCAGGCCAAAGATCTGAAACTGCACTTGCAGCAGCATACAGGCGAGTGCCCCTTCATCTGCGGCACGTGCGGCGAGCGCTTCATTCAGGGCACCGCGCTCGAGAAGCACCGAATGATGCGTCGTCACTTTGACGAGGTCGATGAACGAGGAACGacgcaaacgcaaacacaAACCGCGTAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILAELTHINVNDLLAQRLPQCLCGTCARKLIGAYYYVKQAVAANELLMNHVHGSENNKAVANDCLQEVPMELCAEQHVEVKLETEEEEVDNDITCTELPEFTTVQNANDVENPMGSDVDVDVDNKASNDPLTMVDPVKQEEDGVATRAALAQQHKYKANDDEEDSLDDLPLQLRVQKWKQTEKHRLLKRQIFECKECPKSFKRPRYLKQHSSRVHRSKTDWYSCSFCIRKFSHHEALQAHLKVHGDSKRSANLGENKKAKDIDVNVCKPHGYKLIECMICQSQYDKIVYLRRHLEQHPDIVSFGTRSNMEPNELAELFYPDVKDVSVDELKALIRKDLAAGVFQRFYSITDQSGYEMDLDSSETDSDAELDGDENSKQQRSIPKSKYCCELCQERYQRKYQLYEHQRQTHLWQDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRIANQTFECVDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIASTSKPNGVKRITCKICNMHFERIIDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQLQMQSTPTSTSRIVYVCELCKVQCKRKFEMIQHQRAMHRFDKMPHECDLCIFKCVCKSIMDQHRQSQCRNTEKKYACRRCSYKFMWPENLQQHMQLQHGGIERGASADRRLADYPADQVESASQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGTTQTQTQTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00579412;
80% Identity: -