Basic Information

Insect: Drosophila micromelanica
Gene Symbol: -
Assembly: GCA_004143905.1
Location: SCDX01001175.1:19793-24050[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.4e-06 0.0001 22.4 0.6 1 23 221 244 221 244 0.92

2 17 0.00029 0.021 15.1 1.4 1 23 251 273 251 273 0.97

3 17 0.08 5.6 7.4 0.3 2 23 305 326 304 326 0.95

4 17 0.00063 0.044 14.0 4.3 1 23 416 439 416 439 0.97

5 17 0.011 0.76 10.1 0.3 1 19 446 464 446 466 0.96

6 17 0.0061 0.43 10.9 4.0 1 23 476 498 476 498 0.95

7 17 1.8e-06 0.00013 22.1 0.8 1 23 505 528 505 528 0.97

8 17 7.6e-05 0.0053 16.9 1.2 2 23 536 557 535 557 0.96

9 17 0.0098 0.69 10.3 0.0 2 21 584 603 583 604 0.94

10 17 0.0063 0.44 10.9 2.0 1 23 657 680 657 680 0.96

11 17 0.03 2.1 8.7 0.1 2 23 718 740 717 740 0.94

12 17 0.00031 0.021 15.0 1.0 2 23 781 803 780 803 0.95

13 17 0.00072 0.051 13.9 0.3 1 23 817 839 817 839 0.95

14 17 0.00011 0.0079 16.4 1.6 1 23 845 867 845 867 0.99

15 17 3e-07 2.1e-05 24.5 2.6 1 23 873 895 873 895 0.98

16 17 9.7e-06 0.00068 19.7 3.8 1 23 901 923 901 923 0.97

17 17 0.0018 0.13 12.6 0.2 1 23 929 953 929 953 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.4e-06	0.0001	22.4	0.6	1	23	221	244	221	244	0.92
2	17	0.00029	0.021	15.1	1.4	1	23	251	273	251	273	0.97
3	17	0.08	5.6	7.4	0.3	2	23	305	326	304	326	0.95
4	17	0.00063	0.044	14.0	4.3	1	23	416	439	416	439	0.97
5	17	0.011	0.76	10.1	0.3	1	19	446	464	446	466	0.96
6	17	0.0061	0.43	10.9	4.0	1	23	476	498	476	498	0.95
7	17	1.8e-06	0.00013	22.1	0.8	1	23	505	528	505	528	0.97
8	17	7.6e-05	0.0053	16.9	1.2	2	23	536	557	535	557	0.96
9	17	0.0098	0.69	10.3	0.0	2	21	584	603	583	604	0.94
10	17	0.0063	0.44	10.9	2.0	1	23	657	680	657	680	0.96
11	17	0.03	2.1	8.7	0.1	2	23	718	740	717	740	0.94
12	17	0.00031	0.021	15.0	1.0	2	23	781	803	780	803	0.95
13	17	0.00072	0.051	13.9	0.3	1	23	817	839	817	839	0.95
14	17	0.00011	0.0079	16.4	1.6	1	23	845	867	845	867	0.99
15	17	3e-07	2.1e-05	24.5	2.6	1	23	873	895	873	895	0.98
16	17	9.7e-06	0.00068	19.7	3.8	1	23	901	923	901	923	0.97
17	17	0.0018	0.13	12.6	0.2	1	23	929	953	929	953	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTCATGTGTCGCACCTGCGATGCCAGGGACACGGATAAACTGTACAAGCTGGCAACATCAACCAAAAGATTTCCGGATAAACAGCTCTCAGATATTTTAACTGAATTAACGCACATTGATATGGATGCTAACCTGGCACCACAGCTGCCGCAGTGCCTATGCGGCAATTGTGCCAGAAAATTAATTGGCGCCTATTACTATGTGAAGCAGGCGGTGGTCGCCAACGAGCTGCTGATGAATCATGTGGACCGCCTGgagagcaacaaaacaacGGTCAATGACTGCCTGCAAGAGGCGCCCATGGAGCTGTGCGCCGAGCAGCATGTGGAGATCAAAATGGAAACGGAGGAGGATGAGGCTGAGAATGATATAACCTGCACGGAATTGCCCGAGTTTACAACATTACAAAATGCTAATGATATCGACCTGAATGCTGCCGACGAGCTGGATAACAAGAAATCCGATGATCCGCTAACGATGCTCGAACCCGTTAAACAGGAGGATGAAGCGGCCAAAGCAACAACTGAACAGCTGCGGGAATACAAGGCTGATGTTCAAGACGAAGACTCCCTCGACGATTTGCCCTTGCAGCAGCGTGTGCGCAAGTGGAAACAAACGGACAAGCTGCGCGCTGTAAAGCGCTCAATTTTCAAATGCACCGAATGCCCGAAGAGCTTCAAGCGGCCGGAGTATCTAAAACAGCATGCGGGTCGTGCGCACAAATCGAAAACGGATTGGTTCGCGTGCTCCTATTGCATACGCAAGTTTAGTCACCGGGAAGCGCTGCAGGCGCATCTCAAGGTGCATCGCGACTCGAAGCGATCCGCGAACCTGGGCGAGAGCAAAAAGGCCAAGGATATCGATGTGAACATGTGCAAGCCGCACGGCTATAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACAATAAGATCGCGGACTTGCGACGCCACTTGCAGCAGCATCCGGACATTGTTGGCTTTGGAGGGCGCTCAAATATGCAGCCACATGAGCTGGCCGAATTGTTCTATCCCGATGCCAAAGACGTAACCGTGGAGCAGCTGAAGGCGCTCATTCACAAAGATTTGGCGGCGGGAATTTACCAGCGATTCTATTCGATCACCAATCAGTCCGGCTATGAGATGGATCTGGACAGCTCGGAGACGGAAAGCGAGGCCGAACTGGACGCCGATGAGCAGTGCAAACAGCAGCGCAGCGCGCCCAAAGCCAAATACCACTGTGAACTGTGCCAGGAGCGCTTTCAACGTAAATACCAGCTCTTCGATCATCAGCGACTGACGCACACCTGGCTGGAGGCGCCATATGTCTGCGGACGCTGCGATGCCCGCTTTGTCAGCCTCTATCTGCTGCGGCATCACAACGAGCTGCAGTGCAAAAATGCCCAAAAGCGCTTCCTGTGCCACAGATGTCCGCTACGCTTCCGCTGGCGGCACAATCTGAAGGCGCACATACGCGAGCATCGCATAACCAATCAAACGTACGAGTGCAACGATTGCAAGCGCGTCTTTGACAAGAAGAAATCCCTCACGGTGCATATGCTCAGTGTGCATGCGGAGGAGTCGAAGCTGATACCGTGCCAATGGTGTACCCGCAAGTTCTATCGTCGCGACTATTTGGTGAAGCATCTGAAGCGTCACGGCATACGGGAGCAGGATATACCGCTGGCCGAGACGCTAATCGCGGCCACATCGAAGCCGAACGGCAGCAAGCGCATCACCTGTAAAATTTGCAGCCTGCAGTTCGAGCGGATCGTCGACTTGCGCGCGCACATTCAGCTGGAACTGAAGCTGTCGCTATCGCTGCACCAGAGCTACGATTCGCCGCACAACTACTCCATCACCAACGAGTCCGGCTACGAGCTGCAACTGGCCGACTCCGAGACGGAGGACGAAACGCAGATGCAGTCGAGAGCCTCGCCCAGCACACGATTCGTCTACATCTGCGAGCTGTGCAAGGTGCAGTGCAAGCGCAAATACGAGATGATTCAGCATCAACGTGCCATGCACCGGTTCGACAAGATGCCACACGAGTGCGAGCTGTGCATATTCAAGTGTGTCTGCAAGAGCATCATGGATCAGCATCGGCAATCGCAGTGCCACAGCGCCGAAAAGAAACTGGTGTGCGGCAAGTGCAGCTATAAGTTCATGTGGCCCGAGAATCTGGAACAGCatatgctgctgcagcacggCGGAGGCGGCGGCACAGATGCAACCCAGGCAGCTGCCAGTGAAGCGGCCAGCGCTGATTGCCTGCCCAGCGTCAATGCCGTTCCGGCTGCACCGACGGAGGCGGacgtgcagctgctgcagtgccCGCACTGCGATCGGACGTACCAGATGAAGGCGCGCCTCAACAATCACATACGGGACGTGCACATCAATGGCGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTTCTGTGCTCGCTGTGCGGACGCGAAACCCAATCGGCGGCCACGCTGGTCACCCACATGCGTCGCCACACCGGCGAGAAGCCGTTCAAGTGCGATCTCTGCGAAATGGCCTTTCCACGGCACTCGGAAATGATGTCGCATCGCCGGATGCACACGGGCGAGAAGCCCTTCCATTGCACCGTCTGTGGCAAGGACTTTGCGCGCTCCGACAAGCTGAAGCGGCACATGCTGACGCACAGCGGCCTCAAGCCGCACAAGTGCACGTACTGCGACAAGAGCTATCGGCAGGCCAAGGATCTGAAGctgcatctgcagcagcacacCGGAGAATGTCCGTTCATATGCGGCACGTGCGGCGAACGCTTCATACAGGGCACAGCACTGGAGAAGCATCGCATGATGCGTCGCCACTTTGACGAGGTCGAGGAGCGCACCGCAAACACATAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILTELTHIDMDANLAPQLPQCLCGNCARKLIGAYYYVKQAVVANELLMNHVDRLESNKTTVNDCLQEAPMELCAEQHVEIKMETEEDEAENDITCTELPEFTTLQNANDIDLNAADELDNKKSDDPLTMLEPVKQEDEAAKATTEQLREYKADVQDEDSLDDLPLQQRVRKWKQTDKLRAVKRSIFKCTECPKSFKRPEYLKQHAGRAHKSKTDWFACSYCIRKFSHREALQAHLKVHRDSKRSANLGESKKAKDIDVNMCKPHGYKLIECMICQSQYNKIADLRRHLQQHPDIVGFGGRSNMQPHELAELFYPDAKDVTVEQLKALIHKDLAAGIYQRFYSITNQSGYEMDLDSSETESEAELDADEQCKQQRSAPKAKYHCELCQERFQRKYQLFDHQRLTHTWLEAPYVCGRCDARFVSLYLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGSKRITCKICSLQFERIVDLRAHIQLELKLSLSLHQSYDSPHNYSITNESGYELQLADSETEDETQMQSRASPSTRFVYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRQSQCHSAEKKLVCGKCSYKFMWPENLEQHMLLQHGGGGGTDATQAAASEAASADCLPSVNAVPAAPTEADVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERTANT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00598289;
80% Identity: -