Basic Information

Gene Symbol
-
Assembly
GCA_035046005.1
Location
JAWNOK010000029.1:256135-259266[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 9.5e-06 0.00074 20.1 1.4 1 23 222 245 222 245 0.93
2 17 0.00074 0.058 14.1 1.8 1 23 252 274 252 274 0.98
3 17 0.083 6.5 7.7 1.1 2 23 306 327 305 327 0.95
4 17 0.0011 0.083 13.6 2.4 1 23 417 440 417 440 0.97
5 17 0.069 5.3 7.9 0.5 1 19 447 465 447 468 0.93
6 17 0.0096 0.75 10.6 4.7 1 23 477 499 477 499 0.95
7 17 4.1e-05 0.0032 18.1 0.4 1 23 506 529 506 529 0.97
8 17 9.4e-05 0.0073 16.9 1.2 2 23 537 558 536 558 0.96
9 17 0.0037 0.29 11.9 0.1 2 21 585 604 584 605 0.94
10 17 0.0042 0.33 11.7 1.9 1 23 660 683 660 683 0.96
11 17 0.0075 0.58 10.9 1.0 1 23 720 743 720 743 0.96
12 17 0.00057 0.044 14.5 1.9 2 23 775 797 774 797 0.95
13 17 0.00089 0.069 13.9 0.3 1 23 811 833 811 833 0.95
14 17 0.00012 0.009 16.6 1.2 1 23 839 861 839 861 0.99
15 17 6e-07 4.7e-05 23.8 1.6 1 23 867 889 867 889 0.97
16 17 6.8e-05 0.0053 17.4 4.9 1 23 895 917 895 917 0.97
17 17 0.0013 0.098 13.4 0.2 1 23 923 947 923 947 0.91

Sequence Information

Coding Sequence
ATGAAGCTGCCCGTCATGTGCCGCACTTGCGATGCAAGAGACACAGATAAGCTGTACAAGTTGGCGACAGCCACCAAAAGGTTCCCGGACAAACTGCTCTCCGACATTTTGGTCGAACTAACGCACATCGATTTAAACGAGTCGTTGGCTCAACGATTGCCCCAGTGTCTGTGCGGCACCTGCGCCAGGAAACTGATCAGTGCCTATTACTATGTGAAACAGGCAGTGGCAGCCAATGAGCTGCTGATGAATCATGTCCAGAACCTTGGTAAAACAGTGGCCAACGACTGTTTACAGGAGACGCCCATGGAACTCTGTGCCGAGCAGCATGTGGAGGTTAAACTGGAAACGGAGGAGGATGAACTGGAGAACGATATCACCTGCACGGAACTGCCGGAGTTTACAACAGTACAAAATGCCAACGATGTGGAGAACAGCACAGTGGAATGTGATCTCGATAACAAGAAATCAACGGATCCACTGACCATGCTCGATCCCGTTaagcaggaggaggagggtAATCTAACGAGATCATCATTTGTCCGGGAATACAAATATAAGGCTGACTACGATGAGGACGATTCTCTGGATGATttgccgctgcagcagcgggTACACCAATGGAAGCAGACGGACAAAGTGCGTGGACTCAAGCGACAGATATTCGCGTGCAAGGAATGCCCTAAGAGCTTTAAGCGACCCAGATACCTAAAGCAGCACTCGTCACGTGTACACAAGTCCAAGTCGGATTGGTATTCCTGCTCCTTCTGCATACGCAAGTTTAGTCACAGCGAAGCTCTGCAGGCGCATCTAAAGGTGCACGGAGACTCCAAACGCTCGGCAAACTTGGGCGAGAGCAAAAAGGCCAAGGATATTGATGTAAACGTCTGCAAACCGCATGGCTACAAGCTCATCGAGTGCATGATCTGTCAGAGTCAATACGATAAGATTTCCCATCTGCGTCGCCATCTGGAACAGCATCCGGAGATTGTTAACTTTGGCACACGCTCCACAATGCAGCCACATGAGCTTGCCGAGCTCTTCTATCCCGATTGCAAGGACGTGAGCGTGGATGAGTTGAAGCAACTTATACGCAAGGATTTGGCAGCCGGAATTTATCAACGTTTCTATTCGATAACCGATCAATCTGGCTACGAAATGGATCTGGACAGTTCCGAAACCGACAGCGACTACGAACTGGACGCCGATGAACAGTCCCGGCAGCAACGGAGCATTCCCAGAGCCAAGTACAGCTGTGAGCTGTGCCAGGAGCGATATCAGCGCAAGTATCAGCTTTACGAGCATCAGCGCCAGACGCACACCTGGCTGGAGGCACCACACGTCTGTGGACGTTGTGATGCACGCTTCGTGAGCCTTCAGCTGCTGAGGCATCACAACGAGTCGCAGTGCAAGAATTCCCAGAAACGTTTCCTCTGCCACAAATGTCCACTGCGCTTCCGCTGGAGGCACAATCTGAAGCTGCACATACGGGAGCATAGAATCACAAATCAAACCTTCGAGTGTGCGGACTGCAAGCGTGTCTTTGACAAGAAGAAATCCCTGACGGTTCATTTGCTGAGCGTGCACGCGGAGGAATCGAAGCTGATACCATGCCAGTGGTGCACACGCAAGTTCTATCGACGAGACTATCTGGTGAAGCATCTGAAGCGTCATGGCATACGGGAGCAGGACATTCCCCTAGCGGAGACACTCATAGCGGCCACGTCGAGACCCAATGGCGTTAAGCGAATCACCTGCAAGATTTGTAATCTGCACTTTGAGCGCATGATCGATCTGCGTGCCCACATTCAGCTGGAACTGAAGCTGGCGCTGTCCCTGCACCAGAACTATGATTCACCGCACAACTACTCCATAACGAATCAATCGGGCTACGAACTGCAGCTGGGTGACTCCGAGACAGAGGAtgaaatgcagcagcagctgcagacCACGCAGTCGGCCACTCCTCGAGTGGTCTACGTCTGTGAGCTGTGCAAGGTGCAGTGTCGCAGGAAGTACGAGATGATTCAGCACCAGCGTGCTATGCATCGCTTTGACAAGATGCCACACGAGTGCGAGCTGTGCATCTTCAAGTGTGTCTGCAAGAGCATCATGGATCAGCATCGACTGTCGCAGTGCCACAGTGCAGAGAAAAAGTATGCGTGCAGTCGTTGTGGCTACAAATTCATGTGGCCCGAGAATCTGCATCAGCACATGCAGCTGCAACATGGCGGCGTGGAACGAGCTCCAAGCCAAGATCGTCTGCCAGTTGATGCCGCTGCTGAGCCAGTGGATCCCGCGTCCTCGTCGCTGCAGTTACTGCAATGTCCGCACTGTGATCGCACGTATCAAATGAAGAAGCGACTGAACAATCACATACGGGATGTGCACATCAATGGGGACAGAAAGCGCAAGGAGGCCATCAAGAAGTTCCTCTGCTCGCTGTGTGGCAGGGAGACGCAATCGGCGGCCACACTGGTCACCCACATGCGTCGTCATACCGGCGAGAAGCCCTTCAAATGTGATCTATGCGAAATGGCCTTTCCTCGACACTCGGAAATGATCTCGCACCGTCGCATGCATACGGGCGAGAAGCCATTCCACTGCACAGTATGTGGCAAGGACTTTGCACGCTCCGATAAGCTGACACGGCACATGCTCATCCACAGCGGATTGAAGCCACACAAGTGCACGTACTGCGACAAGAGCTATCGGCAGACGAAGGATctgaaattgcatttgcaacaACACACGGGGGAGTGTCCCTTTGTCTGTGGCACCTGCGGGGAGCGGTTCATACAGGGCACGGCCCTCGAGAAGCATCGCATGATGCGGCGTCACTTCGACGAGGTGGACGAGCGCATCTCCAACCAGGCACTCACCGCATAA
Protein Sequence
MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILVELTHIDLNESLAQRLPQCLCGTCARKLISAYYYVKQAVAANELLMNHVQNLGKTVANDCLQETPMELCAEQHVEVKLETEEDELENDITCTELPEFTTVQNANDVENSTVECDLDNKKSTDPLTMLDPVKQEEEGNLTRSSFVREYKYKADYDEDDSLDDLPLQQRVHQWKQTDKVRGLKRQIFACKECPKSFKRPRYLKQHSSRVHKSKSDWYSCSFCIRKFSHSEALQAHLKVHGDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKISHLRRHLEQHPEIVNFGTRSTMQPHELAELFYPDCKDVSVDELKQLIRKDLAAGIYQRFYSITDQSGYEMDLDSSETDSDYELDADEQSRQQRSIPRAKYSCELCQERYQRKYQLYEHQRQTHTWLEAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKLHIREHRITNQTFECADCKRVFDKKKSLTVHLLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSRPNGVKRITCKICNLHFERMIDLRAHIQLELKLALSLHQNYDSPHNYSITNQSGYELQLGDSETEDEMQQQLQTTQSATPRVVYVCELCKVQCRRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRLSQCHSAEKKYACSRCGYKFMWPENLHQHMQLQHGGVERAPSQDRLPVDAAAEPVDPASSSLQLLQCPHCDRTYQMKKRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLTRHMLIHSGLKPHKCTYCDKSYRQTKDLKLHLQQHTGECPFVCGTCGERFIQGTALEKHRMMRRHFDEVDERISNQALTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00519319;
90% Identity
iTF_00478877; iTF_00569119;
80% Identity
-