Basic Information

Insect: Drosophila siamana
Gene Symbol: -
Assembly: GCA_035047445.1
Location: JAWNPP010000004.1:28082926-28086121[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.4e-06 0.00027 21.1 1.7 1 23 225 248 225 248 0.94

2 17 0.004 0.24 11.8 3.8 1 23 255 277 255 277 0.98

3 17 0.23 14 6.2 0.7 2 23 309 330 308 330 0.94

4 17 0.004 0.24 11.8 0.9 3 23 422 443 420 443 0.96

5 17 0.066 4 7.9 0.5 1 19 450 468 450 471 0.93

6 17 0.0041 0.25 11.7 4.3 1 23 480 502 480 502 0.95

7 17 5e-05 0.003 17.7 0.5 1 23 509 532 509 532 0.96

8 17 9.1e-05 0.0055 16.9 1.2 2 23 540 561 539 561 0.96

9 17 0.0029 0.17 12.2 0.1 2 21 588 607 587 608 0.94

10 17 0.0075 0.45 10.9 2.0 1 23 663 686 663 686 0.96

11 17 0.0057 0.35 11.3 1.0 1 23 723 746 723 746 0.96

12 17 0.00014 0.0083 16.4 1.6 2 23 775 797 774 797 0.95

13 17 0.00086 0.052 13.9 0.3 1 23 811 833 811 833 0.95

14 17 0.00011 0.0067 16.6 1.2 1 23 839 861 839 861 0.99

15 17 3.6e-07 2.1e-05 24.5 2.6 1 23 867 889 867 889 0.98

16 17 1.2e-05 0.0007 19.7 3.8 1 23 895 917 895 917 0.97

17 17 0.0022 0.13 12.6 0.2 1 23 923 947 923 947 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.4e-06	0.00027	21.1	1.7	1	23	225	248	225	248	0.94
2	17	0.004	0.24	11.8	3.8	1	23	255	277	255	277	0.98
3	17	0.23	14	6.2	0.7	2	23	309	330	308	330	0.94
4	17	0.004	0.24	11.8	0.9	3	23	422	443	420	443	0.96
5	17	0.066	4	7.9	0.5	1	19	450	468	450	471	0.93
6	17	0.0041	0.25	11.7	4.3	1	23	480	502	480	502	0.95
7	17	5e-05	0.003	17.7	0.5	1	23	509	532	509	532	0.96
8	17	9.1e-05	0.0055	16.9	1.2	2	23	540	561	539	561	0.96
9	17	0.0029	0.17	12.2	0.1	2	21	588	607	587	608	0.94
10	17	0.0075	0.45	10.9	2.0	1	23	663	686	663	686	0.96
11	17	0.0057	0.35	11.3	1.0	1	23	723	746	723	746	0.96
12	17	0.00014	0.0083	16.4	1.6	2	23	775	797	774	797	0.95
13	17	0.00086	0.052	13.9	0.3	1	23	811	833	811	833	0.95
14	17	0.00011	0.0067	16.6	1.2	1	23	839	861	839	861	0.99
15	17	3.6e-07	2.1e-05	24.5	2.6	1	23	867	889	867	889	0.98
16	17	1.2e-05	0.0007	19.7	3.8	1	23	895	917	895	917	0.97
17	17	0.0022	0.13	12.6	0.2	1	23	923	947	923	947	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGCCGCACTTGCGATGCAAGAGACACTGACAAACTGTATAAGTTGGCGACGGCCACCAAACGGTTCCCGGACAAGTTGCTCTCCGACATTTTAGCTGAATTGACGCACATTAACGTAAACGATGTATTGGCGCAACGTCTGCCACAATGCTTGTGCGGCACCTGCGCAAGAAAACTGATAGGCGCATATTACTATGTGAAGCAGGCGGTGGCCGCAAACGAGCTGCTGATGAACCATGTGCACAACAGCGACAAATCTGTGGCCAACGACTGCCTGCAGGAAGTACCAATGGAGTTATGTGCCGAGCAACATGTGGAGGTTAAACTAGAAACTgaagaggaggaggtggaCAACGATATAACGTGCACGGAATTGCCGGAGTTCACCACAGTACAAAATGTTCACGATGCAGACAACCCAATGGAAAGTGATTTGGATGTGGATAACAAGGCATCTAACGATCCATTGACAATGGTCGATCCTGTCAAACAGGAAGAGGACGGCGTTGGGGTTGCAACGAGGGCAGCGATTGCCCAGGAACACAAATATAAGGCTGATAATGACGAAGAAGAttCCCTGGATAATTTGCCTTTGCAACAGCGTGTGCAAAAGTGGAAACAGACAGAAAAGCATCGAAGATTAAAGCGGCAAATATTCGAATGCAAAGAATGTCCCAAGAGCTTCAAACGCCCTAGGTATCTAAAGCAGCATTCATCACGAGTGCACAAATCAAAAACCGATTGGTATTCCTGTTCATTTTGCATACGAAAGTTTAGTCATCACGACGCACTGCAGGCACATCTGAAGGTACACGGGGATTCGAAGCGGTCGGCCAATTTAGGTGAGAACAAAAAGGCCAAAGATATTGATGTGAATGTGTGCAAACCCCATGGCTACAAACTCATTGAGTGCATGATCTGTCAGAGTCAATACGACAAGATCGCTCATTTGCGACGTCACTTGGAACAGCATCCAGAGATTGTTAGTTTTGGTACACGCTCAAATATGGAACCAAATGAGCTGGCCGAACTATTTTATCCTGATGCCAAGGATGTGAGCGAGGAAGAATTGAAGGCACTCATTCGTAAAGATTTAGCAGCTGGAATTTATCAGCGTTTCTATTCGATAACGAATCAATCCGGCTATGAAATGGATCTGGACAGCTCGGAGACGGATAGTGATGCTGAACTGGATGCAGATGATCATTCGAAGCCACAGCGCAGCATACCGAAAGCGAAATACGGTTGTGAACTTTGTCAAGAGCGTTATCAACGCAAGTATCAATTGTACGAACATCAACGTCAGTCGCATCTGTGGCAGGATGCGCCTCACGTCTGTGGTCGATGCGATGCTCGCTTTGTTAGCCTGCAATTATTGCGGCATCACAATGAGTCGCAGTGCAAGAATTCCCAAAAACGTTTCCTATGCCATAAATGTCCATTGCGCTTTCGCTGGCGTCATAATCTAAAAGTTCACATTAGAGAACACAGAATTGCCAATCAAACATTCGAGTGTGTCGACTGCAAGCGTGTCTTCGATAAGAAGAAGTCGCTAACAGTTCATTTGCTGAGTGTGCATGCCGAGCAATCGAAGCTGATACCGTGCCAGTGGTGCACTCGCAAATTCTATCGACGAGACTATTTGGTCAAGCATCTGAAGCGGCACGGCATCAGAGAACAGGATATTCCGCTGGCGGAGACTCTTATTGCGGCCACCTCAAAGCCGAATGGAAGTAAACGAATTACCTGCAAGATCTGCAATATGCACTTTGACCGCATTATGGATCTGCGTGCTCACATTCAACTCGAACTGAAGCTAGCTCTGTCACTGCACCAGAACTATGATTCGCCACACAATTACTCCATAACAAATGAATCGGGATACGAGCTGCAGCTTGGCGACTCTGAAACAGAggatgaaatgcaaatgcatgtgCAATCAACGCCCCCATCAACTTCGCGCATCGTCTACATCTGTGAATTGTGCAAAGTGCAATGCAAACGAAAGTACGAGATGATACAGCATCAGCGTGCCATGCATCGGTTTGACAAGATGCCACACGAATGCGAGCTATGTATCTTTAAGTGTGTCTGCAAGAGCATCATGGATCAGCATCGGCAATCGCAGTGTCATAGCACTGAGAAGAAATATACGTGCAGCAGATGCAGCTACAAATTTATGTGGCCTGAGAATCTGCAGCAGCATATGCAACTGCAGCATGGCGGAGTCGAGCGAGATGCCAGTACCGATCGTCGACTGCCAGACGATCCCGCCGATCAAGTTGATCCAGCCCTACAATTGCTGCAATGTCCGCACTGCGATCGCACCTATCAAATGAAGTCACGGCTGAACAATCACATTCGAGACGTACACATTAATGGGGATCGCAAGCGCAAAGAGGCCATTAAGAAGTTCTTGTGCTCGTTGTGCGGCCGCGAGACTCAGTCGGCAGCCACCTTGGTTACCCACATGCGTCGCCACACCGGAGAAAAGCCATTCAAATGTGATCTGTGTGAAATGGCCTTTCCAAGGCACTCAGAAATGATATCGCATCGTCGAATGCACACAGGCGAGAAACCATTCCATTGCACAGTTTGCGGCAAGGATTTCGCTCGATCGGACAAGCTGAAGCGCCACATGCTCACCCACAGCGGATTGAAACCGCACAAGTGCACGTATTGCGACAAGAGCTATCGCCAGGCCAAGGATCTAAAGCTACATTTGCAGCAGCATACTGGCGAATGCCCCTTCATCTGTGGCACATGCGGCGAACGCTTTATTCAGGGCACCGCGCTCGAGAAGCATCGAATGATGCGTCGTCACTTTGACGAGGTCGATGAACGGGGAacaacgcaaacacaaacCCAAACCGCGTAG
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILAELTHINVNDVLAQRLPQCLCGTCARKLIGAYYYVKQAVAANELLMNHVHNSDKSVANDCLQEVPMELCAEQHVEVKLETEEEEVDNDITCTELPEFTTVQNVHDADNPMESDLDVDNKASNDPLTMVDPVKQEEDGVGVATRAAIAQEHKYKADNDEEDSLDNLPLQQRVQKWKQTEKHRRLKRQIFECKECPKSFKRPRYLKQHSSRVHKSKTDWYSCSFCIRKFSHHDALQAHLKVHGDSKRSANLGENKKAKDIDVNVCKPHGYKLIECMICQSQYDKIAHLRRHLEQHPEIVSFGTRSNMEPNELAELFYPDAKDVSEEELKALIRKDLAAGIYQRFYSITNQSGYEMDLDSSETDSDAELDADDHSKPQRSIPKAKYGCELCQERYQRKYQLYEHQRQSHLWQDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRIANQTFECVDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGSKRITCKICNMHFDRIMDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQMHVQSTPPSTSRIVYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRQSQCHSTEKKYTCSRCSYKFMWPENLQQHMQLQHGGVERDASTDRRLPDDPADQVDPALQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGTTQTQTQTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00579412;
80% Identity: -