Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: -
Assembly: GCA_037075165.1
Location: JBAMCL010000646.1:10928773-10932414[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.4e-05 0.0029 18.2 3.3 1 23 219 242 219 242 0.94

2 17 0.0012 0.083 13.6 1.9 1 23 249 271 249 271 0.98

3 17 0.44 30 5.6 0.1 2 23 303 324 302 324 0.94

4 17 0.001 0.067 13.9 2.0 1 23 414 437 414 437 0.97

5 17 0.08 5.3 7.9 0.5 1 19 444 462 444 465 0.93

6 17 0.005 0.33 11.7 4.3 1 23 474 496 474 496 0.95

7 17 0.0011 0.076 13.7 0.5 1 23 503 526 503 526 0.95

8 17 0.00011 0.0073 16.9 1.2 2 23 534 555 533 555 0.96

9 17 0.025 1.7 9.5 0.0 2 21 582 601 581 602 0.94

10 17 0.016 1 10.1 2.2 1 23 653 676 653 676 0.96

11 17 0.014 0.92 10.3 0.2 1 23 713 736 713 736 0.94

12 17 0.00017 0.011 16.4 1.6 2 23 775 797 774 797 0.95

13 17 0.001 0.069 13.9 0.3 1 23 811 833 811 833 0.95

14 17 0.00013 0.009 16.6 1.2 1 23 839 861 839 861 0.99

15 17 4.3e-07 2.9e-05 24.5 2.6 1 23 867 889 867 889 0.98

16 17 1.4e-05 0.00093 19.7 3.8 1 23 895 917 895 917 0.97

17 17 0.0026 0.17 12.6 0.2 1 23 923 947 923 947 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.4e-05	0.0029	18.2	3.3	1	23	219	242	219	242	0.94
2	17	0.0012	0.083	13.6	1.9	1	23	249	271	249	271	0.98
3	17	0.44	30	5.6	0.1	2	23	303	324	302	324	0.94
4	17	0.001	0.067	13.9	2.0	1	23	414	437	414	437	0.97
5	17	0.08	5.3	7.9	0.5	1	19	444	462	444	465	0.93
6	17	0.005	0.33	11.7	4.3	1	23	474	496	474	496	0.95
7	17	0.0011	0.076	13.7	0.5	1	23	503	526	503	526	0.95
8	17	0.00011	0.0073	16.9	1.2	2	23	534	555	533	555	0.96
9	17	0.025	1.7	9.5	0.0	2	21	582	601	581	602	0.94
10	17	0.016	1	10.1	2.2	1	23	653	676	653	676	0.96
11	17	0.014	0.92	10.3	0.2	1	23	713	736	713	736	0.94
12	17	0.00017	0.011	16.4	1.6	2	23	775	797	774	797	0.95
13	17	0.001	0.069	13.9	0.3	1	23	811	833	811	833	0.95
14	17	0.00013	0.009	16.6	1.2	1	23	839	861	839	861	0.99
15	17	4.3e-07	2.9e-05	24.5	2.6	1	23	867	889	867	889	0.98
16	17	1.4e-05	0.00093	19.7	3.8	1	23	895	917	895	917	0.97
17	17	0.0026	0.17	12.6	0.2	1	23	923	947	923	947	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTTATCTGTCGCACTTGCGATTCAAGGGAGACGGATAAGTTGTATAAGTTGGCTACCTATACGAAAAGGTTTCCGGAAAAGCAGCTCTCTGACATTTTAGCTGAATTGACCCACATAGAAGCGGATGTTTCTATGgcacagcagctgccgcaATGTTTGTGCGGCACCTGCGCTAGAAAGTTAATCGGCGCCTATTACTACGTCAAACAGGCGCTGGCCGCCCATGAGCTCTTGATGAACCATGTGGAGGACGGCGACAAAGCGGCGGTCACCGACTGCCTGCAGGAGGTGCCAATGGAGCTGTGCGCCGAGCAGCACGTAGAGATTAAATTGGAAACAGAAGACGAGGATGCTGATAATGATATAACCTGCACGGAGCTGCCCGAGTTTACGACAATGCAAAATGCGAATGAGGTGGATGTAGCAGTAGATGAAGATCTAGATAACAAGAAATCGACGGATCCACTAACAATGCTCGATATTGTTAAACAGGAGGAGGATGCCGCTGGCCGAGCAACAAAAGCGCAAGAACACGAAAAGGCTGATAATGACGAAGAAGATTCTCTCGATGATTTGCCTTTGCAACAGCGCGTACATAAGTGGAAACAGAAGGACAAAATTCGTACTTTCAAAAGGCAGATATTCAAATGCCATGAATGCCCCAAGAGTTTCAAACGTGTTGAATATCTGAAACAGCATTCAACGCGCGCCCATAAATCAAAAACCGATTGGTTCTCATGCTCCTTCTGTATACGAAAGTTCAGCCACAGCGAAGCGCTACAGGCCCATCTAAAGGTCCATAGGGACTCCAAGCGATCAGCCAATTTAGGTGAGAGCAAAAAGGCCAAAGATATTGATGTGAACGTATGCAAGCCGCATGGCTATAAGCTCATCGAGTGTATGATCTGTCAAAGTCAATATGATAAAATAGCGGACTTGCGACGTCATCTGGAACAACACCCAGAGATTGTCAGCTTTGGTGCGCGCTCCAATATGCAGCCAAATGAGCTGGCTGAGCTGTTTTATCCCGATGTCAAGGATGTGAGCGAGGAACAACTGAAGGCGCTCATACGCAAAGATTTGGCAGCTGGCATCTATCAGCGTTTCTACTCAATTACGAACCAGTCGGGTTATGAAATGGATTTGGACAGCTCCGAAACGGAGAGCGAAGCTGAACTGGATGGCGAGGAGCAGTCGAAACAACAGCGGACCATACCCAAAGGAAGCTATAGCTGTGAACTGTGCCAAGAGCGTTACCAACGCAAATATCAGCTATACGAACATCAGCGTCTAACACATGCCTGGCAGGAGGCGCCACATGTGTGCGGCCGCTGCGATGCGCGTTTTGTTagcctgcagctgctgcgacaTCATAACGAGTCGCAGTGCAAGAATGCCCAAAAACGTTTCCTGTGCCACAAATGTCCGCTACGCTTCCGCTGGCGGCACAATCTGAAGGTGCACATACGCGAGCACCGTATCACCAATCAAACATACGAGTGTATCGATTGCAAGCGTGTCTTTGATAAAAAGAAATCCTTGACGGTGCACTTGCTTAGTGTGCATGCCGAGCAATCGAAGCTGATACCATGCCAATGGTGCACTCGCAAGTTTTATCGTCGCGACTATCTGGTGAAGCATCTAAAGCGTCACGGCATTCGGGAGCAGGACATACCGCTTGCCGAGACGCTCATTGCGGCCACATCGAAGCCCAACGGTGCCAAACGCATCACCTGCAAAATATGCAGCCTGCAGTTTGAGCGTATCATCGATCTGCGTGCCCACATTCAGCTGGAACTGAAGTTGGCGCTGTCACCACACCAGAACTATGATTCGCCGCATAACTACTCCATAACAAACGACTCCGGCTACGAAATGCAGCTCAACGACTCGGAGACTGAGGATGAAATGCAGATGCAGACCACTACCCCCGCACGGCTTGTCTACGTTTGCGAGCTGTGCAAAGTGCAATGTAAGCGCAAGTTCGAAATGATTCAACATCAGCGTGCCATGCACCGCTTCGACAAGATGCCGCATGAGTGCGAACTATGCATCTTTAAATGCGTCTGCAAGAGCATTATGGAACAGCATAGAGAATCGCAGTGCCACAGTGCTGAGAAGAAGTATGCGTGCAGCAGGTGCGGCTACAAATTCATGTGGCCCGAGAATCTGCAACAGCatgtgcaactgcaacatggCGGAATTGCAGGTACACTGGCCGATGCTAGCGAAGCATTAAGCGCCGATCGCTTACCAACTGATCCTGCGGATCCAGCAGCTAGTGTACCGGCGGATGGCGTACAGCTGCTGCAATGCCCGCACTGCGATCGTACATATCAAATGAAGTCGAGACTCAACAATCATATACGGGATGTGCACATCAATGGCGACCGGAAGCGGAAGGAGGCCATCAAGAAGTTCCTATGCTCACTGTGTGGCCGTGAAACGCAATCGGCGGCCACTCTGGTTACCCACATGCGTCGCCATACGGGCGAGAAGCCATTTAAATGCGATCTGTGTGAGATGGCATTTCCGCGACACTCGGAAATGATATCGCATCGAAGAATGCACACTGGGGAGAAACCATTCCATTGCACTGTTTGTGGCAAGGATTTTGCGCGCTCCGATAAGCTAAAAAGGCACATGCTCACCCACAGTGGTCTGAAACCGCATAAGTGCACATATTGCGATAAGAGCTATCGCCAGGCCAAGGAtctaaaattgcatttgcagcaGCATACCGGTGAGTGCCCATTCATATGTGGCACATGCGGCGAGCGCTTCATTCAGGGCACAGCGCTGGAGAAGCATCGCATGATGCGGCGTCATTTTGACGAGGTAGAGGAACGTAGCACAACCACACTAACTACATAA
Protein Sequence: MKLPVICRTCDSRETDKLYKLATYTKRFPEKQLSDILAELTHIEADVSMAQQLPQCLCGTCARKLIGAYYYVKQALAAHELLMNHVEDGDKAAVTDCLQEVPMELCAEQHVEIKLETEDEDADNDITCTELPEFTTMQNANEVDVAVDEDLDNKKSTDPLTMLDIVKQEEDAAGRATKAQEHEKADNDEEDSLDDLPLQQRVHKWKQKDKIRTFKRQIFKCHECPKSFKRVEYLKQHSTRAHKSKTDWFSCSFCIRKFSHSEALQAHLKVHRDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIADLRRHLEQHPEIVSFGARSNMQPNELAELFYPDVKDVSEEQLKALIRKDLAAGIYQRFYSITNQSGYEMDLDSSETESEAELDGEEQSKQQRTIPKGSYSCELCQERYQRKYQLYEHQRLTHAWQEAPHVCGRCDARFVSLQLLRHHNESQCKNAQKRFLCHKCPLRFRWRHNLKVHIREHRITNQTYECIDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICSLQFERIIDLRAHIQLELKLALSPHQNYDSPHNYSITNDSGYEMQLNDSETEDEMQMQTTTPARLVYVCELCKVQCKRKFEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMEQHRESQCHSAEKKYACSRCGYKFMWPENLQQHVQLQHGGIAGTLADASEALSADRLPTDPADPAASVPADGVQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERSTTTLTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00803751;
80% Identity: -