Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000292.1:250107-253984[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.7e-07 5.9e-05 23.4 1.0 1 23 218 241 218 241 0.95

2 17 0.00083 0.056 14.0 2.9 1 23 248 270 248 270 0.98

3 17 0.56 38 5.1 0.5 2 23 302 323 301 323 0.94

4 17 0.0035 0.24 12.1 3.5 1 23 416 439 416 439 0.97

5 17 0.085 5.8 7.7 0.5 1 19 446 464 446 466 0.94

6 17 0.008 0.54 10.9 4.0 1 23 476 498 476 498 0.95

7 17 2.3e-06 0.00016 22.0 0.8 1 23 505 528 505 528 0.97

8 17 0.0001 0.0068 16.9 1.2 2 23 536 557 535 557 0.96

9 17 0.015 1 10.0 0.3 2 21 584 603 583 604 0.94

10 17 0.0083 0.56 10.9 2.0 1 23 661 684 661 684 0.96

11 17 0.015 1 10.1 0.4 3 23 723 744 721 744 0.94

12 17 0.0004 0.027 15.0 1.0 2 23 786 808 785 808 0.95

13 17 0.00095 0.064 13.8 0.3 1 23 822 844 822 844 0.95

14 17 0.00015 0.01 16.4 1.6 1 23 850 872 850 872 0.99

15 17 3.9e-07 2.7e-05 24.5 2.6 1 23 878 900 878 900 0.98

16 17 1.3e-05 0.00087 19.7 3.8 1 23 906 928 906 928 0.97

17 17 0.0024 0.16 12.6 0.2 1 23 934 958 934 958 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.7e-07	5.9e-05	23.4	1.0	1	23	218	241	218	241	0.95
2	17	0.00083	0.056	14.0	2.9	1	23	248	270	248	270	0.98
3	17	0.56	38	5.1	0.5	2	23	302	323	301	323	0.94
4	17	0.0035	0.24	12.1	3.5	1	23	416	439	416	439	0.97
5	17	0.085	5.8	7.7	0.5	1	19	446	464	446	466	0.94
6	17	0.008	0.54	10.9	4.0	1	23	476	498	476	498	0.95
7	17	2.3e-06	0.00016	22.0	0.8	1	23	505	528	505	528	0.97
8	17	0.0001	0.0068	16.9	1.2	2	23	536	557	535	557	0.96
9	17	0.015	1	10.0	0.3	2	21	584	603	583	604	0.94
10	17	0.0083	0.56	10.9	2.0	1	23	661	684	661	684	0.96
11	17	0.015	1	10.1	0.4	3	23	723	744	721	744	0.94
12	17	0.0004	0.027	15.0	1.0	2	23	786	808	785	808	0.95
13	17	0.00095	0.064	13.8	0.3	1	23	822	844	822	844	0.95
14	17	0.00015	0.01	16.4	1.6	1	23	850	872	850	872	0.99
15	17	3.9e-07	2.7e-05	24.5	2.6	1	23	878	900	878	900	0.98
16	17	1.3e-05	0.00087	19.7	3.8	1	23	906	928	906	928	0.97
17	17	0.0024	0.16	12.6	0.2	1	23	934	958	934	958	0.90

Sequence Information

Coding Sequence: atgaagctGCCCGTCATGTGTCGTACTTGCGATGCAAGGGACACAGATAAACTATACAAATTGGCAACATCCACCAAAAGATTTCCGGACAAACAGCTCTCCGACATTTTAGCCGAATTGACACACATCAATGTGGATGCAACGCTGgcgcaacagctgccgcaATGCCTGTGCGGCAATTGTGCCAGAAAGCTAATTGGCGCCTATTATTATGTGAAACAGGCGTTGGCCGCCAATGAGCTGCTCATGAATCATGTGGACCGCCTGGAGAGCGACAGATCTGCGGTCAATGACTGCCTGCAGGAGGCGCCCATGGAGCTGTGTGCCGAGCAGCATGTGGAGATTAAAATGGAGacagaggaggaggaggctgAAAATGATATAACCTGCACGGAACTGCCGGAGTTTACAACTGTACAAAACGCCCACGATGCGGAAGTGGATGCTGACGATGAGCTGGCTAATAAAAAGTCTGGCGATCCGCTCACCATGCTCGAACCAGTGAAACAGGAGGATGAGCCAACCAATGTGCAGAAACAGGAATATAAGGCTGATATTGAAGATGAGGAATCACTCGATGATTTGCCGCTGCAACAGCGCGTGCGCAAGTGGAAGCAAACGGACAAAGAGCGCACCGTGAAGCgttcaattttcaaatgcaCGGATTGCCCAAAGAGCTTCAAGCGACCGGAGTATCTCAAGCAGCATGCAACACGcgcgcataaatcaaaaaccGATTGGTTCTCCTGCTCCTATTGCATACGCAAGTTCAGTCACAGAGAAGCGCTGCAATCGCATCTGAAAGTGCATCGCGATTCGAAGCGATCAGCCAACTTGGGCGAGAGCAAAAAGGCCAAGGATATTGATGTGAACATGTGCAAACCGCATGGCTATAAGCTAATTGAGTGCATGATCTGTCAGAGTCAATACGATAAGATAGCGGATTTGCGTCGACATTTGGAGCATCATCCGGACATTGTTAATTTTGGCGCACGCTCAAATATGCAGCCACACGAACTGGCCGAGCTGTTCTATCCGGATGCCAAGCATATTAGCGAGGAACAGCTAAAGGTGCTCATACAAAAAGATCTCGCTGCGGGCATTTACCAACGTTTCTATTCGATAACCAATCAATCGGGCTATGAAATGGATCTGGACAGCTCGGAGACGGAAAGCGAGGCTGAACtggatgccgatgccgatgccgagcAGGGCAAACAGCAACGCAGCATACCAAAAGCCAAATATAGCTGTGAACTGTGCCACGAGCGCTTTCAACGCAAATACCAGATCTTCGATCATCAGCGTCTGATGCACAGCTGGCTGGAGGCGCCGCATGTCTGCGGACGCTGCGATGCGCGCTTTGTTagcctccagctgctgcggcatcACAACGAGCTGCAGTGCAAGAACGCACAGAAACGCTTCCTGTGCCACAGATGTCCGCTACGCTTCCGCTGGCGGCACAATCTAAAGGCGCATATACGCGAGCATCGTATCACTAATCAAACGTACGAATGCAACGATTGCAAGCGCGTCTTCGACAAGAAGAAATCGCTGACGGTGCACATGCTCAGCGTGCATGCGGAGCAATCCAAGCTTATACCGTGCCAATGGTGTACACGCAAGTTCTATCGTCGCGACTATCTGGTGAAGCATCTGAAGCGTCATGGCATACGGGAGCAGGATATACCGCTGGCCGAGACGCTCATTGCGGCCACCTCAAAGCCGAACGGCGCCAAGCGCATCACATGCAAAGTTTGTAACCTTCAGTTCGAGCGCATCTGTGAGCTGCGTGCGCACATTCAGCTGGAGCTAAAACTGGCCCTGTCGCTGCACCAGAACTACGACTCGCCCCACAACTACTCCATCACAAACGAATCCGGCTACGAACTGCAGCTGGCCGATTCCGAAACGGAGGATgagatgcaaatgcaaatgcagccgcagccgcgtGCCTCGCCACACACACGACTTGTCTACATCTGCGAGCTGTGCAAAGTACAATGCAAGCGCAAGTACGAGATGATCCAGCATCAGCGGGCCATGCATCGCTTTGACAAGATGCCCCACGAGTGCGAGCTATGCATATTCAAATGCGTTTGCAAGAGCATCATGGATCAGCACAGGCAATCGCAGTGCCAGAGCAGCGATAAGAAACTGGcgtgcagcaaatgcagctaCAAATTCATGTGGCCAGAGaatctgcagcagcacatgcagctgcaacatgGTGGCGTCGCGGAGTCGACCTCTGCAGCCGCTagtgaagcagcagcagcagcagctagcgctgATCGGGTGCCAGCTTTGCCAGCTGATAGCGCAGCGCCGGCAGATgatgtgcagctgctgcagtgtCCGCACTGTGATCGCACGTATCAGATGAAGGCGCGCCTGAACAATCATATACGGGATGTGCACATCAATGGGGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTTCTGTGCTCGCTGTGCGGCCGGGAGACCCAATCGGCGGCCACATTGGTCACACATATGCGACGTCATACGGGCGAGAAGCCCTTCAAATGCGATCTATGTGAAATGGCATTTCCGCGCCATTCCGAGATGATGTCGCATCGCCGGATGCACACCGGCGAGAAGCCGTTCCATTGCACGGTTTGTGGCAAGGATTTTGCGCGATCCGACAAACTGAAGCGGCACATGCTGACGCACAGTGGCCTGAAGCCGCACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCGAAGGATCTGAAGctgcatctgcagcagcacacGGGCGAGTGTCCCTTTATATGCGGCACCTGTGGCGAACGTTTCATACAGGGCACCGCCCTGGAGAAGCATCGCATGATGCGCCGCCACTTCGATGAGGTGGAGGAGCGCAGCACTAATACAACAATTgcttaa
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHINVDATLAQQLPQCLCGNCARKLIGAYYYVKQALAANELLMNHVDRLESDRSAVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTVQNAHDAEVDADDELANKKSGDPLTMLEPVKQEDEPTNVQKQEYKADIEDEESLDDLPLQQRVRKWKQTDKERTVKRSIFKCTDCPKSFKRPEYLKQHATRAHKSKTDWFSCSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDVNMCKPHGYKLIECMICQSQYDKIADLRRHLEHHPDIVNFGARSNMQPHELAELFYPDAKHISEEQLKVLIQKDLAAGIYQRFYSITNQSGYEMDLDSSETESEAELDADADAEQGKQQRSIPKAKYSCELCHERFQRKYQIFDHQRLMHSWLEAPHVCGRCDARFVSLQLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTYECNDCKRVFDKKKSLTVHMLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKVCNLQFERICELRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLADSETEDEMQMQMQPQPRASPHTRLVYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRQSQCQSSDKKLACSKCSYKFMWPENLQQHMQLQHGGVAESTSAAASEAAAAAASADRVPALPADSAAPADDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERSTNTTIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00526712;
80% Identity: -