Basic Information

Insect: Drosophila neonasuta
Gene Symbol: -
Assembly: GCA_005889595.1
Location: MRUE01005121.1:67-3255[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4e-06 0.00039 21.1 1.7 1 23 226 249 226 249 0.94

2 17 0.0017 0.17 12.8 1.8 1 23 256 278 256 278 0.98

3 17 0.35 35 5.5 0.7 2 23 310 331 309 331 0.94

4 17 0.0079 0.79 10.7 4.7 1 23 421 444 421 444 0.96

5 17 0.06 5.9 7.9 0.5 1 19 451 469 451 472 0.93

6 17 0.0037 0.37 11.7 4.3 1 23 481 503 481 503 0.95

7 17 4.6e-05 0.0045 17.7 0.5 1 23 510 533 510 533 0.96

8 17 8.2e-05 0.0081 16.9 1.2 2 23 541 562 540 562 0.96

9 17 0.0033 0.32 11.9 0.1 2 21 589 608 588 609 0.94

10 17 0.0038 0.38 11.7 2.0 1 23 662 685 662 685 0.96

11 17 0.012 1.2 10.1 0.5 1 23 722 745 722 745 0.95

12 17 0.00012 0.012 16.4 1.6 2 23 774 796 773 796 0.95

13 17 0.00078 0.077 13.8 0.3 1 23 810 832 810 832 0.95

14 17 0.0001 0.01 16.6 1.2 1 23 838 860 838 860 0.99

15 17 3.2e-07 3.2e-05 24.5 2.6 1 23 866 888 866 888 0.98

16 17 3.6e-05 0.0036 18.1 3.8 1 23 894 916 894 916 0.97

17 17 0.002 0.19 12.6 0.2 1 23 922 946 922 946 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4e-06	0.00039	21.1	1.7	1	23	226	249	226	249	0.94
2	17	0.0017	0.17	12.8	1.8	1	23	256	278	256	278	0.98
3	17	0.35	35	5.5	0.7	2	23	310	331	309	331	0.94
4	17	0.0079	0.79	10.7	4.7	1	23	421	444	421	444	0.96
5	17	0.06	5.9	7.9	0.5	1	19	451	469	451	472	0.93
6	17	0.0037	0.37	11.7	4.3	1	23	481	503	481	503	0.95
7	17	4.6e-05	0.0045	17.7	0.5	1	23	510	533	510	533	0.96
8	17	8.2e-05	0.0081	16.9	1.2	2	23	541	562	540	562	0.96
9	17	0.0033	0.32	11.9	0.1	2	21	589	608	588	609	0.94
10	17	0.0038	0.38	11.7	2.0	1	23	662	685	662	685	0.96
11	17	0.012	1.2	10.1	0.5	1	23	722	745	722	745	0.95
12	17	0.00012	0.012	16.4	1.6	2	23	774	796	773	796	0.95
13	17	0.00078	0.077	13.8	0.3	1	23	810	832	810	832	0.95
14	17	0.0001	0.01	16.6	1.2	1	23	838	860	838	860	0.99
15	17	3.2e-07	3.2e-05	24.5	2.6	1	23	866	888	866	888	0.98
16	17	3.6e-05	0.0036	18.1	3.8	1	23	894	916	894	916	0.97
17	17	0.002	0.19	12.6	0.2	1	23	922	946	922	946	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCAGTCATGTGTCGCACTTGCGACGCAAGAGACACCGATAAACTTTATAAGTTAGCGACGGCTACCAAAAGATTTCCTGATAAATTGCTCTCCGACATTTTATCTGAATTGACGCACATTGAGGTAGACGATCCATTGGGCCAGCGACTCCCACAATGTTTGTGCGGCACCTGCGCCAGGAAACTAATAAGCGCTTATTACTATGTGAAGCAGGCGCTGGCAGCACACGAGCTGTTGATAAACCATGTGCACGATAGCGACAAAGCCAGTGTGGTGGACTGCCTGCAGGAGGTACCCATGGAACTGTGTGCCGAACAACATGTGGAGGTTAAATTGGAAACGGAAGAAGAGGATGTTGACAACGATATCACCTGCACAGAACTGCCGGAATTCACCACAGTACAAAATGCCAACGATGTTGACAACACATTGAGCAGTGATGTGGATGTAGATGTAACCAAAGCGTCCAACGATCCATTGACAATGGTCGATCCCGTCAAACAGGAAGAGGATGGAGttgcaacaaaagcagcgatTGCACAGGACCATTTGTATAAGGCTGATAATGATAACGACGAAGAAGATTCGCTGGATGATTTGCCTCTACAACAGCGGATACAAAAGTGgaagcaaacagaaaaacatCGCAGATTAAAGAGACAAATATTCGAGTGCAAAGAATGTCCCAAAAGCTTCAAGCGTCCCAGATATCTAAAGCAGCATTCTTCGCGGGTGCATAAATCGAAAACTGATTGGTATTCCTGCTCGTTCTGCATACGAAAATTCAGCCACCTCGAAGCACTGAAAGCACATCTCAAGGTGCACGGGGATTCGAAGAGATCGGCCAATTTGggagaaaataaaaaggcCAAGGATATTGATGTAAATGTGTGCAAACCTCATGGCTATAAGCTTATTGAGTGCATGATCTGCCAAAGTCAATACGATAAGATCGTTCATTTGCGACGCCACTTGGAGCAGCATCCAGAGATTGTTAACTTTGGCACACGGTCCAATATGGAACCCAATGAACTTGCCGAGCTGTTCTATCCAGATGCCAAGGATATGACTGAACAAGAATTAAAAGCGCTCATACGAAAAGATTTAGCTGCTGGCATTTATCAACGTTTCTATTCGATAACGAATCAATCGGGCTATGAAATAGATCTAGACAGCTCAGAGACTGATAGCGAAGCTGAACTGGATGCAGATGAGCATACGAAGCAACAACGTAGCATACCAATAGCCAAATACTGTTGTGAACTTTGCCAAGAACGCTATCAACGGAAGTATCAACTGTACGAGCATCAGCGACAAACGCATCTCTGGCAGGATGCGCCGCATGTCTGTGGTCGCTGCGATGCTCGCTTTGTGAGCCTGCAGTTGTTGCGGCATCACAACGAGTCGCAATGCAAGAATTCGCAAAAACGTTTCCTATGCCACAAATGTCCATTGCGCTTTCGCTGGCGTCACAATCTAAAGGTGCACATCAGGGAGCACAGAATTGCTAATCAAACATTCGAGTGCGTCGATTGCAAACGAGTCTTTGACAAGAAGAAGTCGCTAACAGTTCATTTGCTGAGCGTGCATGCAGAGCAATCGAAGCTGATACCGTGTCAATGGTGCACTCGCAAGTTCTACCGACGCGACTATCTGGTGAAGCACCTCAAGCGACATGGCATTCGAGAGCAGGATATTCCATTGGCGGAGACACTTATTGCGGCCACTTCAAAGCCGAATGGCACCAAACGAATCACCTGCAAGATCTGCAACATGCACTTTGAGCGCATCATCGATCTGCGTGCTCACATTCaactggagctgaagctggctTTATCGCTGCACCAGAACTATGATTCGCCACACAACTATTCCATAACAAATGAATCGGGATACGAACTGCAGCTAGGTGACTCTGAGACAGAGGATGaagtgcaaatgcaaatgcagatgCAATCAACGTCGCGCATCGTCTACGTCTGTGAGCTGTGCAAAGTGCAATGCAAGCGAAAATACGAGATGATACAGCATCAGCGTGCCATGCATCGTTTTGACAAGATGCCACATGAGTGTGAGACCTGCATTTTCAAGTGTGTCTGCAAGAGCATTATGGATCAGCATCGTCAATCGCAGTGCCACAGCACTGAAAAGAAATACGCGTGCAGTAGATGCAGCTACAAGTTTATGTGGCCTGAGAATCTTCAGCAACATATGCAACTCCAACATGGTGGCAATGAACGCGGTGCTAGCGCTGATCGTCGTCTACCCAATGATGTAGCGGATCAAGTCGATCCTGCTCTTCAATTACTACAATGTCCGCACTGCGATCGCACCTACCAAATGAAGTCACGCCTTAACAATCACATACGGGACGTGCACATCAACGGGGATCGCAAACGCAAGGAGGCCATCAAGAAGTTCTTGTGTTCGCTGTGTGGTCGCGAGACGCAATCCGCAGCAACCTTAGTAACCCACATGCGCCGCCATACAGGCGAGAAACCATTTAAATGTGATCTATGTGAAATGGCCTTTCCCCGGCACTCGGAAATGATATCGCATCGTCGCATGCACACCGGCGAGAAACCATTCCATTGTACAGTCTGCGGCAAGGATTTCGCCCGATCCGATAAGCTCAAACGACACATGCTCACCCACAGCGGACTGAAGCCCCACAAGTGCACGTACTGCGAAAAAAGCTATCGCCAGGCCAAGGATCTAAAGCTGCATCTTCAGCAGCATACGGGTGAGTGCCCCTTCATCTGTGGCACATGCGGCGAACGCTTCATCCAGGGCACCGCGCTCGAAAAGCATCGAATGATGCGTCGTCACTTTGACGAGGTCGACGAACGAGGTACAACGCAATCGCAGATGCAGACACAAACCGCTTAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILSELTHIEVDDPLGQRLPQCLCGTCARKLISAYYYVKQALAAHELLINHVHDSDKASVVDCLQEVPMELCAEQHVEVKLETEEEDVDNDITCTELPEFTTVQNANDVDNTLSSDVDVDVTKASNDPLTMVDPVKQEEDGVATKAAIAQDHLYKADNDNDEEDSLDDLPLQQRIQKWKQTEKHRRLKRQIFECKECPKSFKRPRYLKQHSSRVHKSKTDWYSCSFCIRKFSHLEALKAHLKVHGDSKRSANLGENKKAKDIDVNVCKPHGYKLIECMICQSQYDKIVHLRRHLEQHPEIVNFGTRSNMEPNELAELFYPDAKDMTEQELKALIRKDLAAGIYQRFYSITNQSGYEIDLDSSETDSEAELDADEHTKQQRSIPIAKYCCELCQERYQRKYQLYEHQRQTHLWQDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRIANQTFECVDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGTKRITCKICNMHFERIIDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEVQMQMQMQSTSRIVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECETCIFKCVCKSIMDQHRQSQCHSTEKKYACSRCSYKFMWPENLQQHMQLQHGGNERGASADRRLPNDVADQVDPALQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGTTQSQMQTQTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00562597;
80% Identity: iTF_00553834;