Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01001129.1:58304-63013[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.3e-06 0.00054 20.8 0.3 1 23 224 247 224 247 0.92

2 17 0.00068 0.086 13.9 2.0 1 23 254 276 254 276 0.97

3 17 0.14 18 6.6 0.2 2 23 308 329 307 329 0.95

4 17 0.0023 0.29 12.3 4.0 1 23 419 442 419 442 0.97

5 17 0.015 1.9 9.7 0.6 1 19 449 467 449 469 0.96

6 17 0.0061 0.76 10.9 4.0 1 23 479 501 479 501 0.95

7 17 1.8e-06 0.00022 22.0 0.8 1 23 508 531 508 531 0.97

8 17 7.6e-05 0.0095 16.9 1.2 2 23 539 560 538 560 0.96

9 17 0.0041 0.52 11.5 0.1 2 21 587 606 586 607 0.94

10 17 0.0035 0.44 11.7 2.0 1 23 659 682 659 682 0.96

11 17 0.032 4.1 8.6 0.2 3 23 721 742 719 742 0.94

12 17 0.00031 0.038 15.0 1.0 2 23 783 805 782 805 0.95

13 17 0.00072 0.091 13.8 0.3 1 23 819 841 819 841 0.95

14 17 0.00011 0.014 16.4 1.6 1 23 847 869 847 869 0.99

15 17 3e-07 3.7e-05 24.5 2.6 1 23 875 897 875 897 0.98

16 17 9.7e-06 0.0012 19.7 3.8 1 23 903 925 903 925 0.97

17 17 0.0018 0.23 12.6 0.2 1 23 931 955 931 955 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.3e-06	0.00054	20.8	0.3	1	23	224	247	224	247	0.92
2	17	0.00068	0.086	13.9	2.0	1	23	254	276	254	276	0.97
3	17	0.14	18	6.6	0.2	2	23	308	329	307	329	0.95
4	17	0.0023	0.29	12.3	4.0	1	23	419	442	419	442	0.97
5	17	0.015	1.9	9.7	0.6	1	19	449	467	449	469	0.96
6	17	0.0061	0.76	10.9	4.0	1	23	479	501	479	501	0.95
7	17	1.8e-06	0.00022	22.0	0.8	1	23	508	531	508	531	0.97
8	17	7.6e-05	0.0095	16.9	1.2	2	23	539	560	538	560	0.96
9	17	0.0041	0.52	11.5	0.1	2	21	587	606	586	607	0.94
10	17	0.0035	0.44	11.7	2.0	1	23	659	682	659	682	0.96
11	17	0.032	4.1	8.6	0.2	3	23	721	742	719	742	0.94
12	17	0.00031	0.038	15.0	1.0	2	23	783	805	782	805	0.95
13	17	0.00072	0.091	13.8	0.3	1	23	819	841	819	841	0.95
14	17	0.00011	0.014	16.4	1.6	1	23	847	869	847	869	0.99
15	17	3e-07	3.7e-05	24.5	2.6	1	23	875	897	875	897	0.98
16	17	9.7e-06	0.0012	19.7	3.8	1	23	903	925	903	925	0.97
17	17	0.0018	0.23	12.6	0.2	1	23	931	955	931	955	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCTGTCATGTGTCGCACCTGCGATGCCAGGGATACGGATAAACTGTATAAGctggcaacatcaacaaaaagaTTTCCCGATAAACAGCTCTCAGATATTTTAGCTGAATTAACGCACATTGATTTGGATGCCAGCCTGGCGCCACAGCTGCCGCAATGCCTGTGCGGCAACTGCGCCAGAAAATTAATTGGCGCCTATTATTATGTGAAGCAGGCGATGGTCGCCAACGAGCTGCTGATGAATCATGTGGACCGCCTGGAGAGTGACAAAACAACGGTCAATGACTGCCTGCAGGAGGCGCCCATGGAGCTGTGTGCCGAGCAGCATGTAGAGATCAAAATGGAAacagaggaggaggaggccgAGAATGATATAACCTGCACGGAATTGCCTGAGTTTACATCTATACAAAATGCTAATGATGTCGACCTAGATGCTGTTGATGAGCTGGATAACAAGAAGTCTGGTGATCCACTGACGATGCTCGAACCCGTTAAACAGGAGGCGGAAGCGGCCGCCGCTCCCAGAGCAACAACTGAGCAGCTGCGGGAATATAAGGCTGATATTGAAGATGAAGACTCCCTCGATGATTTGCCTTTGCAGCAGCGCGTGCGCAAGTGGAAACAAACGGACAAGCTGCACGCCGTAAAGcgttcaattttcaaatgcgCGGAGTGCCCGAAGAGCTTCAAGCGACCGGAGTATCTGAAGCAGCATGCGGGTCGTGCGCACAAATCGAAAACCGATTGGTTCGCCTGCTCCTATTGCATACGCAAGTTCAGTCACCGCGAAGCGCTGCAGTCGCATCTCAAGGTGCATCGCGACTCGAAACGGTCCGCGAACCTGGGCGAGAGCAAAAAGGCCAAGGATATCGATGTGAATGTGTGCAAGCCGCATGGCTATAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACGATAAGATTGCGGACTTGCGACGtcatttgcagcagcatccgGACATTGTTGGCTTTGGGGCACGGTCAAATATGCAGCCACATGAGCTGGCCGAACTGTTCTATCCCGATGCCAAAGACGTTAGCGTGGACCAGCTGAAGACGCTCATCCGCAAAGATTTGGCGGCGGGCATTTACCAGCGATTCTATTCGATCACCAATCAGTCCGGCTATGAGATGGATCTGGACAGCTCGGAGACGGAAAGCGAAGCCGAAGTGGACGCCGATGAGCAGTGCAaacagcagcgcagcgcaCCCAAAGCTAAATACAACTGTGAGCTGTGCCAGGAGCGCTATCATCGTAAATACCAGCTCTTCGATCATCAGCGTCTCACACACGCCTGGCTGGAGGCGCCTTATGTCTGCGGACGCTGCGATGCGCGCTTTGTCAGCCTCCACCTGCTGCGGCATCACAACGAGCTGCAGTGCAAAAATGCCCAGAAACGTTTCCTGTGCCACAGATGCCCCCTACGCTTCCGCTGGCGGCACAATCTGAAGGCGCACATACGCGAGCATCGCATAACTAATCAAACCTACGAGTGCAACGATTGCAAGCGCGTCTTTGACAAGAAGAAATCCCTGACGGTGCACATGCTCAGCGTGCACGCGGAGGAGTCGAAGCTCATACCGTGCCAGTGGTGTACCCGCAAGTTCTATCGTCGCGACTATTTGGTGAAGCACCTGAAGCGTCACGGCATACGGGAGCAGGATATACCGCTGGCCGAGACGCTGATTGCGGCCACCTCAAAGCCGAACGGCGCCAAGCGCATCACCTGTAAAGTTTGCAACCTGCACTTCGAGCGCATCGTCGATCTGCGTGCGCACATTCAGCTGGAACTGAAGCTGGCGCTGTCGCTGCACCAGAACTACGATTCGCCCCACAACTACTCCATCACCAACGAGTCGGGCtacgagctgcagctggccgacTCCGAGACGGAGGACGAAGCGCAGATGTCGAGGGCCTCGCCCAGCACGCGCTTCGTCTACGTCTGCGAGCTGTGCAAAGTGCAGTGCAAGCGCAAATACGAGATGATTCAGCATCAACGTGCCATGCACCGCTTCGACAAGATGCCACACGAGTGCGAGCTCTGCATATTCAAGTGTGTCTGCAAGAGCATCATGGAACAGCACCGGCAATCGCAGTGCCACAGCGCCGAGAAGAAACTGGCGTGCGGCAAGTGCAGCTACAAATTCATGTGGCCCGAGAATCTGCAGCAGCATATGTTGCTGCaacacggcggcggcggcagcacagAGGCTGCCCAGCCGGATGCTAGTGAAGCAGCTAGCGCTGATCGCATGCCCAGTGTTACTGCCGTTCCGGCTGCTCCGGCGGAGACGgatgtgcagctgctgcagtgtCCGCACTGCGATCGCACGTATCAGATGAAGGCGCGCCTCAACAATCACATACGGGACGTGCACATCAATGGCGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTCCTGTGCTCGCTGTGCGGACGCGAAACCCAATCGGCGGCCACGCTGGTCACCCACATGCGTCGCCACACCGGCGAGAAGCCGTTCAAGTGCGATCTCTGCGAAATGGCATTCCCCAGGCACTCGGAAATGATGTCGCATCGGAGGATGCACACGGGCGAGAAGCCCTTCCATTGCACCGTTTGTGGCAAGGACTTTGCGCGCTCCGACAAGCTGAAGCGGCACATGTTGACGCACAGCGGCCTGAAGCCGCACAAGTGCACGTACTGTGACAAGAGCTATCGCCAGGCCAAGGATCTGAAgctgcatctgcagcagcacacGGGCGAATGTCCTTTCATTTGCGGCACGTGCGGCGAACGCTTCATCCAGGGCACAGCGCTGGAGAAGCATCGCATGATGCGTCGTCACTTTGACGAGGTCGAGGAGCGCACCACAAACACATTAACTGCATAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHIDLDASLAPQLPQCLCGNCARKLIGAYYYVKQAMVANELLMNHVDRLESDKTTVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTSIQNANDVDLDAVDELDNKKSGDPLTMLEPVKQEAEAAAAPRATTEQLREYKADIEDEDSLDDLPLQQRVRKWKQTDKLHAVKRSIFKCAECPKSFKRPEYLKQHAGRAHKSKTDWFACSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIADLRRHLQQHPDIVGFGARSNMQPHELAELFYPDAKDVSVDQLKTLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETESEAEVDADEQCKQQRSAPKAKYNCELCQERYHRKYQLFDHQRLTHAWLEAPYVCGRCDARFVSLHLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKVCNLHFERIVDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLADSETEDEAQMSRASPSTRFVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMEQHRQSQCHSAEKKLACGKCSYKFMWPENLQQHMLLQHGGGGSTEAAQPDASEAASADRMPSVTAVPAAPAETDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERTTNTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00598289;
80% Identity: -