Basic Information

Insect: Drosophila phalerata
Gene Symbol: -
Assembly: GCA_951394115.2
Location: OX596005.2:15189404-15192576[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.4e-06 0.00092 20.1 1.4 1 23 222 245 222 245 0.93

2 17 0.00073 0.072 14.1 1.8 1 23 252 274 252 274 0.98

3 17 0.24 23 6.2 0.7 2 23 306 327 305 327 0.94

4 17 0.0043 0.42 11.7 0.9 3 23 419 440 417 440 0.96

5 17 0.068 6.7 7.9 0.5 1 19 447 465 447 468 0.93

6 17 0.0042 0.41 11.7 4.3 1 23 477 499 477 499 0.95

7 17 4e-05 0.004 18.1 0.4 1 23 506 529 506 529 0.97

8 17 9.2e-05 0.0091 16.9 1.2 2 23 537 558 536 558 0.96

9 17 0.0037 0.36 11.9 0.1 2 21 585 604 584 605 0.94

10 17 0.0022 0.22 12.6 2.8 1 23 662 685 662 685 0.98

11 17 0.014 1.4 10.1 0.5 1 23 722 745 722 745 0.95

12 17 0.00014 0.014 16.4 1.6 2 23 774 796 773 796 0.95

13 17 0.00062 0.061 14.3 0.2 1 23 810 832 810 832 0.95

14 17 0.00011 0.011 16.6 1.2 1 23 838 860 838 860 0.99

15 17 3.6e-07 3.6e-05 24.5 2.6 1 23 866 888 866 888 0.98

16 17 1.2e-05 0.0012 19.7 3.8 1 23 894 916 894 916 0.97

17 17 0.0022 0.22 12.6 0.2 1 23 922 946 922 946 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.4e-06	0.00092	20.1	1.4	1	23	222	245	222	245	0.93
2	17	0.00073	0.072	14.1	1.8	1	23	252	274	252	274	0.98
3	17	0.24	23	6.2	0.7	2	23	306	327	305	327	0.94
4	17	0.0043	0.42	11.7	0.9	3	23	419	440	417	440	0.96
5	17	0.068	6.7	7.9	0.5	1	19	447	465	447	468	0.93
6	17	0.0042	0.41	11.7	4.3	1	23	477	499	477	499	0.95
7	17	4e-05	0.004	18.1	0.4	1	23	506	529	506	529	0.97
8	17	9.2e-05	0.0091	16.9	1.2	2	23	537	558	536	558	0.96
9	17	0.0037	0.36	11.9	0.1	2	21	585	604	584	605	0.94
10	17	0.0022	0.22	12.6	2.8	1	23	662	685	662	685	0.98
11	17	0.014	1.4	10.1	0.5	1	23	722	745	722	745	0.95
12	17	0.00014	0.014	16.4	1.6	2	23	774	796	773	796	0.95
13	17	0.00062	0.061	14.3	0.2	1	23	810	832	810	832	0.95
14	17	0.00011	0.011	16.6	1.2	1	23	838	860	838	860	0.99
15	17	3.6e-07	3.6e-05	24.5	2.6	1	23	866	888	866	888	0.98
16	17	1.2e-05	0.0012	19.7	3.8	1	23	894	916	894	916	0.97
17	17	0.0022	0.22	12.6	0.2	1	23	922	946	922	946	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGTCGCACTTGCGATGCAAGAGACACGGATAAACTGTACAAGTTGGCGACGGCCACCAAAAGGTTTCCGGATAAGCTGCTCTCCGACATTTTAACTGAATTGACGCACATTGATGTAAACGATGCATTGTCACAGCGACTTCCGCAGTGTCTGTGCGGCACCTGCGCCAGGAAACTCATCGGTGCTTATTACTACATAAAACAGGCGCTGGCAGCCAATGAACTGTTGATGAACCATGTCAACAACGGCGACAAAGCCGTCACCAATGACTGCCTGCAGGAGGTGCCCATGGAGCTATGTGCCGAGCAGCATGTTGAGGTTAAACTGGAAACAGAGGAAGATGAGGTTGATAACGATATAACCTGCACAGAACTGCCCGAGTTCACCACAGTACAAAATGCCAATGAGAATGTGGACAACACAGTGGAAAGTGATCATGATAACAAGAAGTCTACAGATCCGCTGACAATGCTTGATCCTGTTAAACAGGAAGAGGATGGCATCACCACAAGGGCAGCGATTGTCCACGAGCATAAATATAAGGCTGATCATGATGAAGACGATTCTCTCGATGATTTGCCTTTACAACAGCGTGTACAAAAGTGGAAGCAGTCGGATAAACTGCGTGGCATTAAACGACAGATATTCGCATGCAAGGAATGTCCAAAGAGCTTCAAACGTCCTAGGTATCTAAAGCAGCATTCATCACGCGTCCACAAATCAAAGTCAGACTGGTACTCCTGCTCCTTCTGTATACGTAAGTTTAGTCACAGTGAAGCTCTGCAGGCGCATCTAAAGGTACACGGAGACTCGAAGCGATCGGCCAATTTGGGCGAGAGTAAAAAGGCCAAGGATATTGATATAAATGTGTGCAAGCCACATGGCTACAAGCTTATCGAGTGCATGATCTGTCAGAGTCAATACGATAAGATTGCCCATCTGAGACGGCATTTGGAACAGCATCCGGAAATTGTTAACTTTGGTGCACGCTCCAATATGGAACCAAATGAGCTCGCCGAACTGTTTTATCCCGATGCCAAGGATGTGAGCGAGAATCAATTGAAGCAACTCATACGTAAAGATTTGGCGGCTGGCATTTATCAGCGTTTCTACTCGATAACGAACCAATCGGGCTATGAAATGGATCTGGACAGCTCCGAAACAGAGAGCGAGGTCGAGCTGGATGGTGATGAGCAGACGCGGCAACATCGTAGCATTCCCAAGGCCAAATACGGTTGCGAGCTGTGCCAGGAGCGTTATCAGCGCAAGTATCAGCTGTATGAGCATCAGCGTCAGACGCACGCTTGGCTGGATGCACCTCATGTCTGTGGTCGCTGTGATGCCCGCTTTGTCAGCCTCCAGCTGCTGAGGCATCACAATGAGTCGCAGTGCAAGAATTCCCAGAAACGTTTCCTGTGCCACAAATGTCCGTTGCGCTTCCGATGGCGACATAATCTCAAGGTGCACATAAGGGAGCACAGGATCACAAATCAGACATTCGAGTGTGCCGATTGCAAGCGCGTCTTTGACAAGAAGAAATCTCTGACGGTCCATTTGCTGAGTGTGCATGCCGAGCAATCGAAACTGATACCGTGTCAATGGTGTACTCGCAAGTTCTATCGACGGGACTATCTGGTTAAGCATCTGAAGCGACACGGCATCCGGGAGCAGGATATTCCGCTGGCCGAGACGCTCATTGCGGCCACATCGAAGCCAAATGGAGCCAAACGGATCACGTGCAAGATCTGCAACATGCATTTTGAGCGCATCATCGATCTGCGTGCTCATATTCAGCTGGAACTGAAGCTGTCGCTGTCACTGCATCAGAACTACGACTCACCGCACAACTATTCCATAACGAACGAATCTGGGTATGAGCTGCAGTTGGGCGATTCCGAGACCGAGGATGAaatgcagatgcagatgcagtCAACACCGGCCAACCAGTCAACTCAACGTCTTGTCTACATCTGTGAGCTGTGCAAGGTGCAATGCCGGCGGAAATACGAGATGATACAACACCAGCGTACTATGCATCGATTTGACAAGATGCCACATGAGTGCGAAATCTGCATCTTTAAGTGTGTCTGCAAGAGCATCATGGATCAGCACAGGCAATCGCAGTGTCACAGCGCCGAGAAGAAATATGCGTGCAGCAGATGCAGCTACAAGTTTATGTGGCCCGAGAATCTGCAGCAACATATGCAGCTGCAGCACAATGGCATGGAACGTGCCCCAAGTACTGATCGTATACCCGATGATCCAGCCGATCCGGGAGTGGATCCGACCCTACAGCTGCTACAATGCCCGCACTGTGATCGCACCTATCAAATGAAATCACGACTGAACAATCACATAAGGGATGTGCACATCAATGGGGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTCCTATGCTCGCTGTGTGGCCGCGAGACGCAATCGGCCGCCTCCTTGGTCACCCACATGCGTCGTCACACCGGCGAGAAGCCCTTCAAATGCGATCTCTGCGAAATGGCATTTCCCCGGCACTCGGAAATGATATCGCATCGCCGTATGCACACGGGAGAGAAGCCCTTCCACTGTACCGTATGCGGCAAGGACTTTGCCCGCTCCGACAAACTGAAACGTCACATGCTGACCCACAGCGGACTGAAGCCGCACAAGTGCACCTACTGCGATAAGAGCTATCGCCAGGCCAAGGATCTGAAACTGCATTTGCAGCAGCACACCGGCGAATGTCCCTTCATCTGCGGCACGTGTGGTGAGCGGTTCATTCAGGGCACGGCGCTGGAGAAGCACCGCATGATGCGGCGTCACTTTGACGAGGTGGACGAACGCGTCTCCACACAAGCGTTAACCTGA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILTELTHIDVNDALSQRLPQCLCGTCARKLIGAYYYIKQALAANELLMNHVNNGDKAVTNDCLQEVPMELCAEQHVEVKLETEEDEVDNDITCTELPEFTTVQNANENVDNTVESDHDNKKSTDPLTMLDPVKQEEDGITTRAAIVHEHKYKADHDEDDSLDDLPLQQRVQKWKQSDKLRGIKRQIFACKECPKSFKRPRYLKQHSSRVHKSKSDWYSCSFCIRKFSHSEALQAHLKVHGDSKRSANLGESKKAKDIDINVCKPHGYKLIECMICQSQYDKIAHLRRHLEQHPEIVNFGARSNMEPNELAELFYPDAKDVSENQLKQLIRKDLAAGIYQRFYSITNQSGYEMDLDSSETESEVELDGDEQTRQHRSIPKAKYGCELCQERYQRKYQLYEHQRQTHAWLDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRITNQTFECADCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICNMHFERIIDLRAHIQLELKLSLSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQMQMQSTPANQSTQRLVYICELCKVQCRRKYEMIQHQRTMHRFDKMPHECEICIFKCVCKSIMDQHRQSQCHSAEKKYACSRCSYKFMWPENLQQHMQLQHNGMERAPSTDRIPDDPADPGVDPTLQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAASLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERVSTQALT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00507025;
80% Identity: -