Basic Information

Insect: Drosophila americana
Gene Symbol: -
Assembly: GCA_018152915.1
Location: JAECXQ010000444.1:4889810-4893115[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 7.5e-07 4.4e-05 23.4 1.0 1 23 223 246 223 246 0.95

2 17 0.00072 0.042 14.0 2.9 1 23 253 275 253 275 0.98

3 17 0.48 28 5.1 0.5 2 23 307 328 306 328 0.94

4 17 0.0047 0.28 11.5 3.5 1 23 418 441 418 441 0.96

5 17 0.074 4.3 7.7 0.5 1 19 448 466 448 468 0.94

6 17 0.0069 0.41 10.9 4.0 1 23 478 500 478 500 0.95

7 17 2e-06 0.00012 22.0 0.8 1 23 507 530 507 530 0.97

8 17 8.7e-05 0.0051 16.9 1.2 2 23 538 559 537 559 0.96

9 17 0.012 0.69 10.2 0.3 2 21 586 605 585 606 0.94

10 17 0.0072 0.42 10.9 2.0 1 23 661 684 661 684 0.96

11 17 0.013 0.77 10.1 0.4 3 23 723 744 721 744 0.94

12 17 0.00035 0.02 15.0 1.0 2 23 784 806 783 806 0.95

13 17 0.00083 0.048 13.8 0.3 1 23 820 842 820 842 0.95

14 17 0.00013 0.0075 16.4 1.6 1 23 848 870 848 870 0.99

15 17 3.4e-07 2e-05 24.5 2.6 1 23 876 898 876 898 0.98

16 17 1.1e-05 0.00065 19.7 3.8 1 23 904 926 904 926 0.97

17 17 0.0021 0.12 12.6 0.2 1 23 932 956 932 956 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	7.5e-07	4.4e-05	23.4	1.0	1	23	223	246	223	246	0.95
2	17	0.00072	0.042	14.0	2.9	1	23	253	275	253	275	0.98
3	17	0.48	28	5.1	0.5	2	23	307	328	306	328	0.94
4	17	0.0047	0.28	11.5	3.5	1	23	418	441	418	441	0.96
5	17	0.074	4.3	7.7	0.5	1	19	448	466	448	468	0.94
6	17	0.0069	0.41	10.9	4.0	1	23	478	500	478	500	0.95
7	17	2e-06	0.00012	22.0	0.8	1	23	507	530	507	530	0.97
8	17	8.7e-05	0.0051	16.9	1.2	2	23	538	559	537	559	0.96
9	17	0.012	0.69	10.2	0.3	2	21	586	605	585	606	0.94
10	17	0.0072	0.42	10.9	2.0	1	23	661	684	661	684	0.96
11	17	0.013	0.77	10.1	0.4	3	23	723	744	721	744	0.94
12	17	0.00035	0.02	15.0	1.0	2	23	784	806	783	806	0.95
13	17	0.00083	0.048	13.8	0.3	1	23	820	842	820	842	0.95
14	17	0.00013	0.0075	16.4	1.6	1	23	848	870	848	870	0.99
15	17	3.4e-07	2e-05	24.5	2.6	1	23	876	898	876	898	0.98
16	17	1.1e-05	0.00065	19.7	3.8	1	23	904	926	904	926	0.97
17	17	0.0021	0.12	12.6	0.2	1	23	932	956	932	956	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCCGTCATGTGTCGTACTTGCGATGCAAGGGACACAGATAAACTATACAAATTGGCTACATCCACCAAAAGATTTCCGGATAAACAGCTCTCCGACATTTTAGCTGAATTGACACACATCAATTTGGATGAAACGCTGGCGCAACAGCTGCCGCAATGCCTGTGCTGTACTTGTGCCAGAAAGCTAATTGGCGCCTATTATTATGTGAAACAGGCATTGGCCGCCAATGAGCTGCTCATGAATCATGTGGGCCGCCTGGAGAGCGACATAACTGCGGTCAATGACTGCCTGCAGGAGGCGCCCATGGAGCTGTGTGCCGAGCAGCATGTGGAGATTAAAATGGAGACAGAGGAGGAGGAGGCTGAAAATGATATAACCTGCACAGAACTGCCGGAGTTTACAACTGTACAAAACGCCCACGATGTGGAGGTGGATGCCGACGATGAGCTGGATAATAAAAAGTCTGACGATCCGCTTACCATGCTCGAGCCAGTGAAACAGGAGGATGAGCCATCCGCTGCCAGAGCAACCAATGTGCAGAAACAGGAATATAAGGCTGATATTGAAGACGAGGAATCACTTGATGATTTGCCTCTGCAACAGCGCGTGCGCAAGTGGAAGCGAATGGACAAGATGCGCACCGTAAAACGTTCAACTTTCAAATGCACGGATTGCCCAAAAAGCTTCAAGCGGCCCGAGTATCTTAAGCAGCATGCAACACGGGCGCACAAATCAAAAACCGATTGGTTCTCCTGCTCTTATTGCATACGCAAGTTCAGTCACAGAGAAGCGCTGCAATCGCATCTGAAAGTGCATCGCGATTCCAAGCGTTCAGCCAACTTGGGCGAGAGCAAAAAGGCCAAGGATATTGATGTGAACATGTGCAAGCCGCATGGCTACAAGCTAATCGAGTGCATGATCTGTCAGAGTCAATACGAGAAGATAGCGGATTTGCGTCGACATCTGGAGCATCATCCGGACATCGTTAATTTTGGCGCACGCTCAAATATGCAGCCACACGAACTGGCCGAGCTATTCTATCCGGATGCCAAGCATATCAGCGAGGAACAACTAAAGGTGCTCATACACAAAGATCTGGCCGCGGGCATTTACCAACGTTTCTACTCAATAACCAACCAATCGGGCTATGAAATGGATCTGGACAGCTCGGAGACGGAAAGCGAGGCTGAACTGGATGGCGAGGAGCAGGGCAAACAGCAACGCCGCATACCCAAAGCCAAATACAACTGTGAACTGTGCCACGAACGCTTTCAACGCAAATACCAGATCTTCGATCATCAGCGTCTGATGCACGCCTGGCTGGAGGCGCCGCATGTCTGCGGACGCTGTGATGCGCGCTTTGTTAGCCTCCAGCTGCTGCGACATCACAACGAGCTCCAGTGCAAGAACGCACAAAAACGTTTCCTGTGCCACAGATGTCCGCTACGCTTCCGCTGGCGGCACAATCTAAAGGCACATATACGCGAGCACCGTATTACTAATCAAACGTACGAATGCAACGATTGCAAGCGCGTCTTCGACAAGAAGAAATCCCTGACGGTGCACATGCTCAGCGTGCATGCGGAGGAATCCAAGCTCATACCGTGCCAATGGTGTACACGCAAGTTCTATCGTCGTGACTATCTGGTGAAGCATCTGAAGCGTCATGGCATACGGGAACAGGATATACCGCTGGCCGAGACCCTCATTGCGGCCACCTCAAAGCCCAACGGCGCCAAGCGCATCACCTGCAAGGTTTGTAATCTTCAGTTCGAGCGCATCTGTGATCTGCGTGCGCACATTCAGCTGGAGCTAAAACTGGCCCTGTCGCTGCACCAGAACTACGACTCGCCGCACAACTACTCCATCACAAACGAATCCGGCTACGAGCTACAGCTGGGCGACTCCGAAACGGAGGATGAAATGCAAACGCAAATGCAGCCGCGTGCCTCGCCACTCACGCGACTTGTCTACATCTGCGAGCTGTGCAAAGTGCAATGCAAGCGCAAGTACGAGATGATCCAGCATCAGCGGGCCATGCATCGCTTTGACAAAATGCCGCACGAGTGCGAGCTATGCATATTCAAATGCGTATGCAAGAGCATCATGGATCAACACAAGCAATCGCAGTGCCAGAGCAGTGATAAGAAACTGGCATGCAGCAAATGCAGCTATAAATTCATGTGGCCAGAGAATCTGCAGCAGCACATGCAACTGCAGCATGGTGGCACGGAGTTGACCTCTGCGGCCGCTAGTGAATCAGCAGCAGCAGCTAGCGCGGATCAGGTGCCAGCTTTGTCAGCTGATACCGCAGCGCCGGCAGATGATGTGCAGCTGCTGCAGTGTCCACACTGTGATCGCACGTATCAGATGAAGGCGCGCCTGAACAATCATATACGGGATGTGCACATCAATGGGGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTTCTGTGCTCGCTGTGCGGGCGGGAGACCCAGTCGGCGGCCACATTGGTCACCCATATGCGACGTCATACGGGCGAGAAGCCCTTCAAATGCGATCTATGTGAAATGGCATTTCCGCGCCATTCGGAGATGATGTCGCACCGCCGGATGCATACGGGCGAGAAGCCATTCCATTGCACGGTGTGCGGCAAGGATTTTGCGCGATCCGACAAACTGAAGCGGCACATGCTGACGCACAGTGGCCTGAAGCCGCACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCAAAGGATCTGAAGCTCCATCTACAGCAGCACACGGGCGAGTGCCCCTTTATATGCGGCACCTGTGGCGAACGTTTCATACAGGGCACCGCCCTGGAGAAGCACCGCATGATGCGCCGCCACTTTGACGAGGTGGAGGAGCGCAGCACTAATACATCAATTGCTTAA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHINLDETLAQQLPQCLCCTCARKLIGAYYYVKQALAANELLMNHVGRLESDITAVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTVQNAHDVEVDADDELDNKKSDDPLTMLEPVKQEDEPSAARATNVQKQEYKADIEDEESLDDLPLQQRVRKWKRMDKMRTVKRSTFKCTDCPKSFKRPEYLKQHATRAHKSKTDWFSCSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDVNMCKPHGYKLIECMICQSQYEKIADLRRHLEHHPDIVNFGARSNMQPHELAELFYPDAKHISEEQLKVLIHKDLAAGIYQRFYSITNQSGYEMDLDSSETESEAELDGEEQGKQQRRIPKAKYNCELCHERFQRKYQIFDHQRLMHAWLEAPHVCGRCDARFVSLQLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKVCNLQFERICDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQTQMQPRASPLTRLVYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHKQSQCQSSDKKLACSKCSYKFMWPENLQQHMQLQHGGTELTSAAASESAAAASADQVPALSADTAAPADDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERSTNTSIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00526712;
80% Identity: -