Basic Information

Insect: Drosophila nigritarsus
Gene Symbol: -
Assembly: GCA_035044305.1
Location: JAWNMF010000240.1:5461254-5464447[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.9e-05 0.0021 18.6 0.9 1 23 220 243 220 243 0.96

2 17 0.013 0.94 10.2 2.2 2 23 251 272 250 272 0.96

3 17 0.38 28 5.6 0.1 2 23 304 325 303 325 0.94

4 17 0.0079 0.59 10.9 4.1 1 23 416 439 416 439 0.97

5 17 0.08 5.9 7.7 0.5 1 19 446 464 446 466 0.94

6 17 0.02 1.5 9.6 5.0 1 23 476 498 476 498 0.95

7 17 3e-06 0.00023 21.6 0.9 1 23 505 528 505 528 0.97

8 17 9.3e-05 0.007 16.9 1.2 2 23 536 557 535 557 0.96

9 17 0.00072 0.054 14.1 0.3 2 21 584 603 583 604 0.94

10 17 0.041 3.1 8.6 2.2 1 23 658 681 658 681 0.96

11 17 0.018 1.4 9.7 0.4 2 23 719 741 718 741 0.94

12 17 0.00014 0.011 16.4 1.6 2 23 777 799 776 799 0.95

13 17 0.00089 0.066 13.9 0.3 1 23 813 835 813 835 0.95

14 17 0.00012 0.0086 16.6 1.2 1 23 841 863 841 863 0.99

15 17 3.7e-07 2.7e-05 24.5 2.6 1 23 869 891 869 891 0.98

16 17 1.7e-06 0.00013 22.4 2.2 1 23 897 919 897 919 0.98

17 17 0.0013 0.094 13.4 0.2 1 23 925 949 925 949 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.9e-05	0.0021	18.6	0.9	1	23	220	243	220	243	0.96
2	17	0.013	0.94	10.2	2.2	2	23	251	272	250	272	0.96
3	17	0.38	28	5.6	0.1	2	23	304	325	303	325	0.94
4	17	0.0079	0.59	10.9	4.1	1	23	416	439	416	439	0.97
5	17	0.08	5.9	7.7	0.5	1	19	446	464	446	466	0.94
6	17	0.02	1.5	9.6	5.0	1	23	476	498	476	498	0.95
7	17	3e-06	0.00023	21.6	0.9	1	23	505	528	505	528	0.97
8	17	9.3e-05	0.007	16.9	1.2	2	23	536	557	535	557	0.96
9	17	0.00072	0.054	14.1	0.3	2	21	584	603	583	604	0.94
10	17	0.041	3.1	8.6	2.2	1	23	658	681	658	681	0.96
11	17	0.018	1.4	9.7	0.4	2	23	719	741	718	741	0.94
12	17	0.00014	0.011	16.4	1.6	2	23	777	799	776	799	0.95
13	17	0.00089	0.066	13.9	0.3	1	23	813	835	813	835	0.95
14	17	0.00012	0.0086	16.6	1.2	1	23	841	863	841	863	0.99
15	17	3.7e-07	2.7e-05	24.5	2.6	1	23	869	891	869	891	0.98
16	17	1.7e-06	0.00013	22.4	2.2	1	23	897	919	897	919	0.98
17	17	0.0013	0.094	13.4	0.2	1	23	925	949	925	949	0.91

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTCATGTGTCGCACTTGCGATGCACGAGAAACGGACAAACTGTACAAGCTGGCAACGTCCACCAAAAGATTTCCGGATAAACAGCTTGCGGACATTTTGGTCGAATTGACACACATCGATCTTGATGAGGCATTGTCGCAACAGCTGCCACAATGTCTGTGCGGCAATTGTGCCCGCAAATTGATCGGCGCCTATTACTACGTGAAGCAGGCGCTGGCCGCCAACGAGCTGCTGATGCACCATGTGGAACGGTTGGACGGCGACAAGACGGGCGCCAATGACTGCCTGAGGGAGGCGCCCATGGAGATGTGCGCCGAGCAGCATGTGGAGgtCAAATTGGAaacggaggaggaggatgctGAGAATGATATCACCTGCACAGAACTGCCCGAGTTTACCACAGTACAAAATGCAATCGATGTGGAATTGGATGATGAGCTGGATGGCAAAAAGTCGGCAGATCCACTGAATATGCTCGAACCAGTTAAACAGGAAGAGGATGCTGCAGCTGGACCAACAAATGCACAGGCACAAGAACTTACGGCTGCCCTAGATGAGGAAGACTCTATGGATGATTTGCCATTGCAAGAGCGCGCCAGGAAGTGGAAACAGACGGCTAAGTTGCACACACTCAAACGAGCCATCTTCAAGTGCAAGGAATGCCCAAAGAACTTCAAGCGCATCGAGCTATTGAAGCAGCATGCATCCCGTGCGCACAAATCGAAGACGGATTGGTTGTCGTGCTCGTTTTGCATACGCAAGTTTAGTCACCGGGAAGCGCTGCAAATGCATCTCAAGGTGCATCGCGACTCCAAGCGCTCGGCGAATCTGGGCGAGAGCAAAAAGGCCAAGGACATCGATGTGAACGTGTGCAAGCCCCATGGATACAAGCTTATCGAGTGCATGATCTGTCAGAGTCAATACGATAAGATTGCGGACCTGCGACGTCATCTGGAGCAGCATCCGGAAATTGTTGGCTTCGGGGCACGCTCGAATATGCAGCCGCATGAACTGGCCGAGCTCTTTTATCCAGACGCCAAGGATGTTAGCGAGGATCAGTTGAAGGCGCTCATACGCAAAGATCTTTCCGCTGGGATCTATCAACGTTTCTACTCGATAACCAATCAATCTGGCTACGAAATGGATTTGTACAGCTCCGAGACGGAGAGCGAGGCTGAACTGGATGCCGAGGAGCGAGAAGCGAATCAACAGCGCAGCATACCCAAAGCCAAATATAGTTGTGAGTTGTGCCAAGAGCGCTGCCAGCGCAAATATCAGCTGTACGATCATCAGCGCCAGATGCACGCATGGCTGGAGGCGCCACACGTCTGTGGCCGTTGCGATGCCCGCTTCGTCAGCCTCCAGCTGCTGCGGCATCACAACGAACTGCAGTGCAAGAATGCCCAGAAGCGCTTCCTATGCCACAGATGTCCATTGCGATTCCGCTGGCGGCACAATCTCAAGACCCACATACGCGAGCATCGCATCACAAATCAAACATTCGAGTGCAACGACTGCAAGCGTGTCTTTGACAAGAAGAAGTCGCTGACGGTGCACATGCTCAGTGTGCATGCCGAGGAATCAAAACTGATACCCTGCCAATGGTGCACGCGGAAATTCTATCGTCGCGATTACCTGGTCAAGCATTTGAAGCGTCATGGGATTCGGGAGCAGGATATACCGCTGGCCGAGACACTCATTGCGGCCACATCGAAACCGAATGGCGCCAAACGGATCACGTGCAAAATATGCAATCTGCACTTTGAGCGCATCAGCGATCTGCGCTCGCACATTCAGCTGGAACTGAAGTTGGCCCTCTCCATGCACCAGAACTATGATTCGCCGCACAACTACTCGATCACAAACGAATCGGGGTATGAACTGCAGCTGGGCGACTCCGAAACGGAGGATGAGTCGCATATGCATTCGGCATCCTCGCCTACAAGTCCACGCTCCGTCTACATCTGTGAACTGTGCAAAGTGCAATGCAAACGCAAATTCGAAATGGTTCAGCATCAGCGTGCGATGCATCGCTTCGACAAGATGCCCTACGAGTGCGAACTGTGCATCTTCAAATGTGTCTGCATGAGCATCATGGAGCAGCACCGGCAATCGCAGTGCCACAGCACGGCGAAGCAGTTATCGTGTGGCAAATGCAGTTACAAATTCATGTGGCCAGAGAATCTGCAACAACACATGCAGCTGCAACATGGGAGCATCGCTGACAGCACCAGCCCATTGGAACCAGGCGCAAATAGCGCCAATCACATTCCAGCCATTCCAACGGATCCTCCAGCGGATAGTGTGCAGCTTTTGCAGTGTCCCCACTGCGATCGCACGTATCAAATGAAGTCGCGGCTCAACAATCACATACGGGACGTGCACATCAATGGGGATCGCAAGCGGAAGGAGGCCGTCAAGAAGTTCCTGTGCTCGCTGTGCGGCCGGGAAACGCAATCCGCTGCCACATTGGTCACGCATATGCGTCGCCACACCGGCGAGAAGCCCTTCAAGTGCGATCTGTGCGAAATGGCCTTTCCACGGCACTCGGAAATGATATCGCATCGACGGATGCATACGGGCGAGAAACCCTTCCATTGCACCGTCTGCGGCAAGGATTTCGCACGCTCCGACAAGCTGAAGCGGCACATGCTAACGCACAGTGGGCTGAAGCCATACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCCAAGGATCTGAAACTGCATCTCCAGCAGCACACCGGCGAGTGCACATTCGTCTGCGGTACCTGCGGCGAACGCTTCATACAGGGCACAGCGCTGGAGAAGCATCGCATGATGCGGCGCCATTTCGACGAGGTCGAGGAGCGTGCCACAAACACATTAACTGCATAG
Protein Sequence: MKLPVMCRTCDARETDKLYKLATSTKRFPDKQLADILVELTHIDLDEALSQQLPQCLCGNCARKLIGAYYYVKQALAANELLMHHVERLDGDKTGANDCLREAPMEMCAEQHVEVKLETEEEDAENDITCTELPEFTTVQNAIDVELDDELDGKKSADPLNMLEPVKQEEDAAAGPTNAQAQELTAALDEEDSMDDLPLQERARKWKQTAKLHTLKRAIFKCKECPKNFKRIELLKQHASRAHKSKTDWLSCSFCIRKFSHREALQMHLKVHRDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIADLRRHLEQHPEIVGFGARSNMQPHELAELFYPDAKDVSEDQLKALIRKDLSAGIYQRFYSITNQSGYEMDLYSSETESEAELDAEEREANQQRSIPKAKYSCELCQERCQRKYQLYDHQRQMHAWLEAPHVCGRCDARFVSLQLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKTHIREHRITNQTFECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICNLHFERISDLRSHIQLELKLALSMHQNYDSPHNYSITNESGYELQLGDSETEDESHMHSASSPTSPRSVYICELCKVQCKRKFEMVQHQRAMHRFDKMPYECELCIFKCVCMSIMEQHRQSQCHSTAKQLSCGKCSYKFMWPENLQQHMQLQHGSIADSTSPLEPGANSANHIPAIPTDPPADSVQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAVKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPYKCTYCDKSYRQAKDLKLHLQQHTGECTFVCGTCGERFIQGTALEKHRMMRRHFDEVEERATNTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00495265;
80% Identity: -