Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000018.1:1893900-1897801[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.8e-06 0.00011 22.4 0.6 1 23 221 244 221 244 0.92

2 17 0.00036 0.022 15.1 1.4 1 23 251 273 251 273 0.97

3 17 0.099 6.1 7.4 0.3 2 23 305 326 304 326 0.95

4 17 0.00031 0.019 15.3 3.9 1 23 416 439 416 439 0.97

5 17 0.013 0.83 10.1 0.3 1 19 446 464 446 466 0.96

6 17 0.0075 0.46 10.9 4.0 1 23 476 498 476 498 0.95

7 17 2.2e-06 0.00014 22.1 0.8 1 23 505 528 505 528 0.97

8 17 9.4e-05 0.0058 16.9 1.2 2 23 536 557 535 557 0.96

9 17 0.0028 0.17 12.3 0.1 2 21 584 603 583 604 0.94

10 17 0.0078 0.48 10.9 2.0 1 23 657 680 657 680 0.96

11 17 0.038 2.3 8.7 0.1 2 23 718 740 717 740 0.94

12 17 0.00038 0.023 15.0 1.0 2 23 782 804 781 804 0.95

13 17 0.00089 0.055 13.8 0.3 1 23 818 840 818 840 0.95

14 17 0.00014 0.0086 16.4 1.6 1 23 846 868 846 868 0.99

15 17 3.7e-07 2.3e-05 24.5 2.6 1 23 874 896 874 896 0.98

16 17 1.2e-05 0.00074 19.7 3.8 1 23 902 924 902 924 0.97

17 17 0.0022 0.14 12.6 0.2 1 23 930 954 930 954 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.8e-06	0.00011	22.4	0.6	1	23	221	244	221	244	0.92
2	17	0.00036	0.022	15.1	1.4	1	23	251	273	251	273	0.97
3	17	0.099	6.1	7.4	0.3	2	23	305	326	304	326	0.95
4	17	0.00031	0.019	15.3	3.9	1	23	416	439	416	439	0.97
5	17	0.013	0.83	10.1	0.3	1	19	446	464	446	466	0.96
6	17	0.0075	0.46	10.9	4.0	1	23	476	498	476	498	0.95
7	17	2.2e-06	0.00014	22.1	0.8	1	23	505	528	505	528	0.97
8	17	9.4e-05	0.0058	16.9	1.2	2	23	536	557	535	557	0.96
9	17	0.0028	0.17	12.3	0.1	2	21	584	603	583	604	0.94
10	17	0.0078	0.48	10.9	2.0	1	23	657	680	657	680	0.96
11	17	0.038	2.3	8.7	0.1	2	23	718	740	717	740	0.94
12	17	0.00038	0.023	15.0	1.0	2	23	782	804	781	804	0.95
13	17	0.00089	0.055	13.8	0.3	1	23	818	840	818	840	0.95
14	17	0.00014	0.0086	16.4	1.6	1	23	846	868	846	868	0.99
15	17	3.7e-07	2.3e-05	24.5	2.6	1	23	874	896	874	896	0.98
16	17	1.2e-05	0.00074	19.7	3.8	1	23	902	924	902	924	0.97
17	17	0.0022	0.14	12.6	0.2	1	23	930	954	930	954	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTCATGTGTCGCACCTGCGATGCCAGGGATACGGATAAACTGTATAAGCTGGCAACATCAACCAAAAGATTTCCGGATAAACAGCTCTCAGATATTTTAACTGAATTAACGCACATTGATATGGATGCTAGTCTGGCACCACAACTGCCCCAGTGCCTATGCGGCAATTGTGCCAGAAAATTAATTGGCGCCTATTACTATGTGAAACAGGCGGTGGTCGCCAATGAGCTGCTGATGAATCATGTGGACCGCCTGgagagcaacaaaacaacGGTCAATGACTGCCTGCAGGAGGCGCCCATGGAGTTGTGTGCCGAGCAGCATGTAGAGATCAAAATGGAaacggaggaggaggaggctgAAAATGATATAACCTGCACGGAATTGCCCGAATTTACAACATTACAAAATGCCAATGATATCGACCTGGATGCTGCCGATGAGCTGGATAATAAGAAATCCAGTGATCCGCTAACAATGCTCGAACCCGTTAAACAGGAGAATGAAGCGGGTAAAGCGTCAACTGAGCAACTGCGGGAATATAAGGCTGATGTTGACGACGAAGACTCCCTCGATGATCTGCCTTTGCAGCAGCGCGTGCGCAAGTGGAAACAAACGGACAAACTGCGCGCTGTAAAGCGCTCAATTTTCAAATGTACCGAATGCCCGAAAAGCTTCAAGCGGCCGGAGTACCTTAAACAGCATGCGGGTCGTGCGCACAAATCGAAAACTGATTGGTTCGCGTGCTCCTATTGCATACGCAAGTTTAGTCACCGCGAAGCACTGCAAGCGCATCTGAAGGTGCATCGCGACTCCAAGCGCTCCGCGAACTTGGGCGAGAGCAAAAAGGCCAAGGATATCGATGTGAACATGTGCAAACCGCACGGGTATAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACAATAAGATTGCGGACTTGCGACGCCACTTGCAGCAGCATCCGGACATTGTTGGATTCGGGGGTCGCTCAAATATGCAGCCACATGAGCTGGCCGAACTATTCTACCCCGATGCCAAAGACATCACTGTAGAGCAGCTAAAGGCGCTCATCCACAAAGATTTGGCGGCGGGGATTTACCAGCGATTCTATTCGATCACAAATCAGTCCGGCTATGAGATGGATCTGGACAGCTCGGAGACGGAAAGCGAGGGTGAACTGGATGCCGATGAGCAGTGCAAACAGCAGCGCAGCGCACCCAAAGCCAAATACCACTGTGAGCTGTGCCAGGAGCGCTTTCAACGTAAATACCAGCTCTTCGATCATCAGCGTGTGACGCACACCTGGCTGGAAGCGCCTTACGTCTGCGGACGCTGCGATGCGCGCTTTGTCAGCCTTTATCTGCTGCGGCATCACAACGAACTGCAGTGCAAAAATGCCCAAAAACGCTTCCTGTGCCACAGATGCCCGCTACGCTTCCGCTGGCGGCACAATCTAAAGGCACACATACGAGAGCATCGCATAACCAATCAAACGTACGAGTGCAATGATTGCAAGCGCGTCTTTGACAAGAAGAAATCCCTGACGGTGCATATGCTCAGTGTGCATGCGGAGGAGTCGAAGCTCATACCGTGCCAGTGGTGTACCCGCAAGTTCTATCGTCGCGACTATTTGGTGAAGCATCTGAAGCGTCACGGCATACGGGAGCAGGACATACCGCTGGCCGAGACGCTAATCGCGGCCACATCGAAGCCGAACGGCAGCAAGCGCATCACCTGTAAAATTTGCAACCTGCACTTCGAGCGCATCGTTGACTTACGAGCGCACATCCAGCTGGAACTGAAGCTGGCGCTATCGCTGCACCAGAATTACGATTCGCCGCACAACTACTCCATTACCAACGAGTCCGGATACGAACTGCAACTGGCCGACTCCGAGACGGAGGACGaaatgcagttgcagtcgaGAGCCTCACCCAGCACACGGTTCGTCTACATCTGCGAGCTGTGCAAAGTGCAGTGCAAGCGCAAATACGAGATGATTCAGCATCAACGCGCCATGCACCGTTTCGACAAAATGCCACACGAGTGCGAGTTGTGCATATTCAAGTGTGTCTGCAAGAGCATCATGGATCAGCATCGGCAATCGCAGTGCCACAGCGCCGAAAAGAAACTGGTGTGCGGCAAATGCAGCTATAAATTCATGTGGCCCGAGAATCTGGAACAGCATATGCTGCTGCAACATGgcgggggcggcggcggcacagAGGCTACCCAGGCGGATGCCAGTGAAGCAGCTGGCGCTGATTGTATGCCTAGCGTTAATGCTGTTCCGGCTGCGCCGACGGAGGCGGATGTGCAACTGCTGCAGTGTCCGCACTGCGATCGCACGTATCAGATGAAGGCTCGCCTCAACAATCACATACGGGATGTGCACATCAATGGCGATCGCAAGCGCAAGGAGGCCATCAAAAAGTTTCTGTGCTCGCTGTGCGGACGCGAAACGCAATCAGCGGCCACACTGGTCACCCACATGCGTCGCCACACCGGCGAGAAGCCGTTCAAGTGCGATCTCTGCGAAATGGCTTTTCCACGGCACTCGGAAATGATGTCGCATCGCAGGATGCACACTGGCGAGAAGCCCTTCCACTGCACCGTCTGTGGCAAGGACTTTGCGCGCTCCGACAAGCTGAAGCGGCACATGCTGACGCACAGCGGCCTCAAACCGCACAAGTGCACGTACTGTGACAAGAGTTATCGGCAGGCCAAGGATCTGAAgctgcatctgcagcagcacacGGGCGAATGTCCTTTCATATGTGGCACGTGCGGCGAGCGCTTCATACAGGGCACAGCACTGGAGAAGCATCGCATGATGCGTCGCCACTTTGACGAGGTCGAGGAGCgcacaacaaacacataa
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILTELTHIDMDASLAPQLPQCLCGNCARKLIGAYYYVKQAVVANELLMNHVDRLESNKTTVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTLQNANDIDLDAADELDNKKSSDPLTMLEPVKQENEAGKASTEQLREYKADVDDEDSLDDLPLQQRVRKWKQTDKLRAVKRSIFKCTECPKSFKRPEYLKQHAGRAHKSKTDWFACSYCIRKFSHREALQAHLKVHRDSKRSANLGESKKAKDIDVNMCKPHGYKLIECMICQSQYNKIADLRRHLQQHPDIVGFGGRSNMQPHELAELFYPDAKDITVEQLKALIHKDLAAGIYQRFYSITNQSGYEMDLDSSETESEGELDADEQCKQQRSAPKAKYHCELCQERFQRKYQLFDHQRVTHTWLEAPYVCGRCDARFVSLYLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGSKRITCKICNLHFERIVDLRAHIQLELKLALSLHQNYDSPHNYSITNESGYELQLADSETEDEMQLQSRASPSTRFVYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRQSQCHSAEKKLVCGKCSYKFMWPENLEQHMLLQHGGGGGGTEATQADASEAAGADCMPSVNAVPAAPTEADVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERTTNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00598289;
80% Identity: -