Basic Information

Insect: Drosophila pruinosa
Gene Symbol: -
Assembly: GCA_018150935.1
Location: JAECWR010000094.1:3434752-3437874[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.7e-06 0.00031 21.1 1.7 1 23 218 241 218 241 0.94

2 17 0.00093 0.076 13.5 1.9 1 23 248 270 248 270 0.98

3 17 0.33 27 5.5 0.7 2 23 302 323 301 323 0.94

4 17 0.017 1.4 9.6 4.1 1 23 414 437 414 437 0.96

5 17 0.056 4.6 7.9 0.5 1 19 444 462 444 465 0.93

6 17 0.0035 0.29 11.7 4.3 1 23 474 496 474 496 0.95

7 17 4.3e-05 0.0035 17.8 0.5 1 23 503 526 503 526 0.96

8 17 7.7e-05 0.0063 17.0 1.2 2 23 534 555 533 555 0.96

9 17 0.0024 0.2 12.3 0.1 2 21 582 601 581 602 0.94

10 17 0.0064 0.52 10.9 2.0 1 23 655 678 655 678 0.96

11 17 0.036 3 8.5 2.5 1 23 715 738 715 738 0.96

12 17 0.00012 0.0096 16.4 1.6 2 23 766 788 765 788 0.95

13 17 0.00073 0.06 13.9 0.3 1 23 802 824 802 824 0.95

14 17 9.5e-05 0.0078 16.7 1.2 1 23 830 852 830 852 0.99

15 17 3e-07 2.5e-05 24.5 2.6 1 23 858 880 858 880 0.98

16 17 9.9e-06 0.00081 19.8 3.8 1 23 886 908 886 908 0.97

17 17 0.0018 0.15 12.6 0.2 1 23 914 938 914 938 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.7e-06	0.00031	21.1	1.7	1	23	218	241	218	241	0.94
2	17	0.00093	0.076	13.5	1.9	1	23	248	270	248	270	0.98
3	17	0.33	27	5.5	0.7	2	23	302	323	301	323	0.94
4	17	0.017	1.4	9.6	4.1	1	23	414	437	414	437	0.96
5	17	0.056	4.6	7.9	0.5	1	19	444	462	444	465	0.93
6	17	0.0035	0.29	11.7	4.3	1	23	474	496	474	496	0.95
7	17	4.3e-05	0.0035	17.8	0.5	1	23	503	526	503	526	0.96
8	17	7.7e-05	0.0063	17.0	1.2	2	23	534	555	533	555	0.96
9	17	0.0024	0.2	12.3	0.1	2	21	582	601	581	602	0.94
10	17	0.0064	0.52	10.9	2.0	1	23	655	678	655	678	0.96
11	17	0.036	3	8.5	2.5	1	23	715	738	715	738	0.96
12	17	0.00012	0.0096	16.4	1.6	2	23	766	788	765	788	0.95
13	17	0.00073	0.06	13.9	0.3	1	23	802	824	802	824	0.95
14	17	9.5e-05	0.0078	16.7	1.2	1	23	830	852	830	852	0.99
15	17	3e-07	2.5e-05	24.5	2.6	1	23	858	880	858	880	0.98
16	17	9.9e-06	0.00081	19.8	3.8	1	23	886	908	886	908	0.97
17	17	0.0018	0.15	12.6	0.2	1	23	914	938	914	938	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCTGTAATGTGTCGTACTTGCGATGCTAGAGACACTGATAAACTATATAAGTTGGCGACTGCCACGAAAAGATTCCCGGATAAGTTGCTTTCCGATATTTTAGCAGAATTGACACACATTGACGCGAACGATATATTGACTCAGCGACTGCCGCAATGTCTGTGCGGCACCTGCGCAAGAAAACTAATCGGTGCATACTACTATGTAAAGCAGGCGGTGGCAGCAAACGAGCTATTGATGAACCATGTTCAGGACAGCGACAAAGCCTTAGTCAATGATTGCCTACAGGAAGTGCCCATGGAGCTATGTGCCGAGCAGCATGTAGAGGTTAAATTAGAAACAGAAGATGAGGAAGTAGAAAACGATATAACCTGCACAGAACTGCCGGAGTTCACCACAGTACAAAATGTCAATGACGCGGACAACACAATGGAAAGCGATTTGCAAAACAAAGCATCTAATGATCCATTGACAATGATTGAACCCGTCAAACAGGAAGAGGATGAAATTCGAGCGGCAATTGCCCAAGAGAAAAAATTTAAGGCGGATAATGATGAAGACTCCCTTGATGATTTGCCTTTACAGCAACGCGTAGAAAAGTGGAAAGAGACAGAAAAACATCGAAGACTAAAGAGGCAAATATTCGAATGCAAGGAATGTCCAAAAAGCTTCAAGCGCCCTAGGTATCTAAAGCAACATTCATCGCGTGTCCATAAGTCTAAAACGGATTGGTTTTCCTGTTCGTTTTGTATACGAAAGTTCAGTCACAATGAAGCACTACAAGCACATTTAAAGGTGCATGGTGATTCCAAGCGATCTGCCAATTTGGGTGAGAATAAAAAGGCGAAAGATATTGATGTAAATATATGCAAGCCACATGGCTATAAGCTCATTGAGTGTATGATATGTCAAAGTCAATACGATAAGATAGTTCATTTGCGCCGTCATCTGGAACAGCATCCAGACATTCTTAACTTTGGCACACGAGCAAATATGGAACCAAATGAGCTTGCGGAGCTATTTTATCCCGATGTCAAGGATGTAAGCGAAGAAGAATTAAAAGTGCTCATCCGTAAAGACTTAGCTGCAGGCATTTTTCAACGTTTCTATTCAATAACGAACCAATCTGGATACGAAATGGATCTTGACAGTTCCGAAACGGATAGCGACGGCGAACTGGATGCTGATTGTCATTCAAAGCTGGTAAGCAGTATTATGCCGAAATCCAAATATTGTTGTGAACTTTGCCAGGCACGTTATCAACGGAAGTATCAGTTGTACGAACACCAGCGTCAGTCGCATGTCTGGCAGGATGCGCCTCACGTGTGTGGTCGGTGTGATGCTCGCTTCGTTAGTCTTCAACTGCTGCGGCATCATAATGAATCACAGTGCAAGAATTCCCAGAAACGTTTTTTATGCCACAAATGTCCACTACGTTTTCGATGGCGACATAATTTGAAGGTTCATATAAGGGAACATAGAATTACTAATCAAACCTTTGAATGTGTCGATTGCAAACGCGTCTTTGATAAAAAAAAATCGCTTACAGTTCATTTATTGAGTGTGCATGCGGAGCAATCGAAGCTGATACCATGCCAATGGTGCACACGTAAATTCTATCGACGAGACTATCTTGTAAAGCATCTAAAGCGGCATGGTATCAGAGAACAGGATATTCCCCTAGCCGAGACACTTATTGCAGCAACTTCAAAGCCGAATGGAGCGAAGCGAGTCACCTGCAAGATCTGCAATACGCACTTTGAACGGATTATTGATTTGCGTGCTCACATTCAACTAGAACTGAAGCTATCACTGTCTCTGCATCAGAATTATGATTCGCCACATAACTACTCCATAACGAATGAATCAGGGTACGAGTTACAGCTTGGCGACTCTGAGACAGAGGATGAAATGCAACTGCAGTCTACATCCGCATCGACTTCTCGTATTGCCTACATTTGTGAGTTGTGTAAAGTACAATGCAAACGAAAGTACGAGATGATACAGCATCAGCGTGCAATGCATCGATTTGATAAGATGCCACACGAATGTGAGCTGTGTATCTTCAAGTGTGTCTGCAAGAGCATCATGGATCAGCATCGGCAATCGCAGTGCCACAATACAGAGAAGAAATTCACGTGCAACAGATGTAGCTATAAGTTTATGTGGCCTGAGAATCTGCATCAGCACATGCAACTCCAACATCGAGGCATAGAACGAGGGCAAAGTACGGATCGCTTACCAGATGATGATGCTGATCAGGTCGATCCAGCCTTACAGCTACTGCAATGCCCGCACTGCGATCGAACCTATCAAATGAAATCACGACTCAACAATCATATACGAGACGTTCACATCAATGGGGATCGCAAGCGCAAGGAGGCCATCAAGAAGTTCCTTTGTTCGCTGTGTGGGCGCGAGACGCAATCTGCAGCCACTTTGGTCACCCACATGCGGCGTCACACTGGTGAGAAGCCTTTCAAATGCGATCTGTGCGAAATGGCATTTCCACGCCACTCGGAAATGATATCCCATCGTAGAATGCACACAGGTGAAAAACCATTCCACTGCACAGTTTGCGGTAAGGATTTTGCCCGATCCGACAAACTCAAGCGACACATGCTCACCCACAGTGGATTGAAGCCGCATAAGTGCACATACTGCGATAAAAGCTATCGACAAGCTAAAGATCTAAAACTCCATTTGCAGCAACATACAGGCGAGTGCCCCTTCATCTGTGGCACATGTGGTGAGCGATTTATACAAGGCACCGCGTTAGAGAAGCATCGAATGATGCGTCGCCACTTCGACGAGGTTGACGAACGAGGAGCAACTTGA
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATATKRFPDKLLSDILAELTHIDANDILTQRLPQCLCGTCARKLIGAYYYVKQAVAANELLMNHVQDSDKALVNDCLQEVPMELCAEQHVEVKLETEDEEVENDITCTELPEFTTVQNVNDADNTMESDLQNKASNDPLTMIEPVKQEEDEIRAAIAQEKKFKADNDEDSLDDLPLQQRVEKWKETEKHRRLKRQIFECKECPKSFKRPRYLKQHSSRVHKSKTDWFSCSFCIRKFSHNEALQAHLKVHGDSKRSANLGENKKAKDIDVNICKPHGYKLIECMICQSQYDKIVHLRRHLEQHPDILNFGTRANMEPNELAELFYPDVKDVSEEELKVLIRKDLAAGIFQRFYSITNQSGYEMDLDSSETDSDGELDADCHSKLVSSIMPKSKYCCELCQARYQRKYQLYEHQRQSHVWQDAPHVCGRCDARFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKVHIREHRITNQTFECVDCKRVFDKKKSLTVHLLSVHAEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRVTCKICNTHFERIIDLRAHIQLELKLSLSLHQNYDSPHNYSITNESGYELQLGDSETEDEMQLQSTSASTSRIAYICELCKVQCKRKYEMIQHQRAMHRFDKMPHECELCIFKCVCKSIMDQHRQSQCHNTEKKFTCNRCSYKFMWPENLHQHMQLQHRGIERGQSTDRLPDDDADQVDPALQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERGAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00589671; iTF_00595377; iTF_00509234; iTF_00520764; iTF_00614319;
80% Identity: -