Basic Information

Insect: Drosophila aldrichi
Gene Symbol: -
Assembly: GCA_035045965.1
Location: JAWNOM010000117.1:464053-467379[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.8e-06 0.00028 21.2 0.7 1 23 221 244 221 244 0.95

2 17 0.00073 0.054 14.0 2.9 1 23 251 273 251 273 0.98

3 17 0.36 27 5.6 0.1 2 23 305 326 304 326 0.94

4 17 0.00078 0.058 13.9 3.3 1 23 415 438 415 438 0.97

5 17 0.085 6.3 7.5 0.2 1 19 445 463 445 465 0.95

6 17 0.0071 0.52 10.9 4.0 1 23 475 497 475 497 0.95

7 17 2.1e-06 0.00015 22.0 0.8 1 23 504 527 504 527 0.97

8 17 8.9e-05 0.0066 16.9 1.2 2 23 535 556 534 556 0.96

9 17 0.0056 0.42 11.2 0.8 2 21 583 602 582 603 0.94

10 17 0.0041 0.3 11.7 2.0 1 23 657 680 657 680 0.96

11 17 0.024 1.8 9.3 0.9 3 23 719 740 717 740 0.94

12 17 0.00036 0.026 15.0 1.0 2 23 780 802 779 802 0.95

13 17 0.00084 0.062 13.8 0.3 1 23 816 838 816 838 0.95

14 17 0.00013 0.0097 16.4 1.6 1 23 844 866 844 866 0.99

15 17 3.5e-07 2.6e-05 24.5 2.6 1 23 872 894 872 894 0.98

16 17 1.1e-05 0.00084 19.7 3.8 1 23 900 922 900 922 0.97

17 17 0.0021 0.16 12.6 0.2 1 23 928 952 928 952 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.8e-06	0.00028	21.2	0.7	1	23	221	244	221	244	0.95
2	17	0.00073	0.054	14.0	2.9	1	23	251	273	251	273	0.98
3	17	0.36	27	5.6	0.1	2	23	305	326	304	326	0.94
4	17	0.00078	0.058	13.9	3.3	1	23	415	438	415	438	0.97
5	17	0.085	6.3	7.5	0.2	1	19	445	463	445	465	0.95
6	17	0.0071	0.52	10.9	4.0	1	23	475	497	475	497	0.95
7	17	2.1e-06	0.00015	22.0	0.8	1	23	504	527	504	527	0.97
8	17	8.9e-05	0.0066	16.9	1.2	2	23	535	556	534	556	0.96
9	17	0.0056	0.42	11.2	0.8	2	21	583	602	582	603	0.94
10	17	0.0041	0.3	11.7	2.0	1	23	657	680	657	680	0.96
11	17	0.024	1.8	9.3	0.9	3	23	719	740	717	740	0.94
12	17	0.00036	0.026	15.0	1.0	2	23	780	802	779	802	0.95
13	17	0.00084	0.062	13.8	0.3	1	23	816	838	816	838	0.95
14	17	0.00013	0.0097	16.4	1.6	1	23	844	866	844	866	0.99
15	17	3.5e-07	2.6e-05	24.5	2.6	1	23	872	894	872	894	0.98
16	17	1.1e-05	0.00084	19.7	3.8	1	23	900	922	900	922	0.97
17	17	0.0021	0.16	12.6	0.2	1	23	928	952	928	952	0.90

Sequence Information

Coding Sequence: ATGAAGCTACCCGTCATGTGTCGCACATGCGATGCAAGAGACACGGATAAACTATACAAGCTGGCTACATCCACCAAACGATTTCCGGATAAACAGCTCTCCGATATTTTAGCTGAACTAACGCACATTGAATTGGATGAAACTTTGGCGCAACAGCTGCCGCAATGTCTGTGTGGTAATTGCGCGAGGAAGCTAATTGGCGCCTATTATTATGTGAAGCAGGCGCATGCAGCAAATGAGCTCCTGATGAATCATGTGGACCGCCTGGAGAGCAATAAAACTACAGTCAACGACTGCCTGCAGGAGGCGCCCATGGAGTTGTGTGCCGAGCAACATGTGGAGaTCAAAATGGAaacagaggaggaggaggctgAGAATGATATCACCTGCACAGAACTGCCGGAGTTCACAACAGTACAAAATGCCAACGATGTGGACCTGGAGCTAGATAACAAAAAATCCAATGATCCGCTCAACATGCTCGAGCCAGTGAAACAGGAGGTGGAGCCAACCGCCGGTCGCACACCAAATTTACAAGAGCCGCAAGAATATAAGGCTGATATTGAGCAAGATGAagaATCCCTTGATGATTTGCCTTTGCAACAGCGCGCACGCAAGTGGAAGCAAACCGGAACGATTCGTGCTGTAAAGCGTTCCATTTTTAAGTGTACCGAATGCCCCAAGATTTTCAAACGACCTGAATATCTGAAGCAGCATGCAACACGAGCGCATAAGTCAAAAACCGATTGGTTTTCCTGCTCTTATTGCATACGCAAGTTCAGTCATCGAGAGGCTCTGCAGTCGCACCTGAAGGTGCATCGAGACTCAAAGCGGTCGGCGAATCTGGGCGAAAGTAAAAAGGCCAAGGATATAGATTTAAACATGTGCAAGCCACATGGCTATAAGCTAATCGAGTGTATGATTTGCCAGAGTCAATACGATAAGATAGCGGATCTGCGACGACATCTGGAACAGCATCCGGATATCGTTGGATTCGGTGCACGCTCCAATATGCAACCGCACGAGCTGGCCGAGCTCTTCTATCCGGATGCCAAGCATATCAGCCTGGAGCAGCTGAAAGCGCTCATACGCAAAGATCTGGATGCCGGCATTTATCAACGTTTCTATTCCATTACCAATCAGTCGGGCTATGAAATGGACCTGGACAGCTCCGAGACAGAAAGCGATGCTGACCGGGATGTcgatgagcagcagctgaagcgcAACATACCCAAAGCCAAGTACACCTGTGAACTGTGCAACGAACGCTGTCAGCGTAAATACCAGCTCTTTGATCATCAACGTCTGGCGCACGCCTGGCTGGATGCGCCCCATGTCTGCGGACGCTGTGATGCGCGCTTTGTtagcctgcagctgctgcgacaACACAACGAGCTACAGTGTAAGAATGCTCAGAAACGCTTCCTCTGCCACAGATGTCCGCTGCGCTTCCGCTGGCGTCACAATCTAAAGGCGCATATACGTGAACACCGCATTATTAATCAAACCTATGAGTGCAACGATTGCAAGCGTGTGTTCGACAAGAAGAAATCCCTCACCGTACACATGCTCAGCGTACATGCGGAGGAATCGAAACTCATACCGTGCCAATGGTGTACCCGCAAGTTCTATCGACGCGACTATTTGGTGAAGCATCTGAAGCGACATGGCATACGGGAGCAGGATATACCGCTCGCCGAGACGCTAATTGCAGCCACCGCGAAACCAAATGGCGCTAAGCGCATCACCTGCAAGATTTGTAACCTTCACTTTGAACGCATCTGTGACCTGCGAGCGCACATCCAGCTGGAGCTTAAGCTGGCCTTGTCGCTGCACCAGAACTACGACTCCTTGCAAAACTACTCGATTACAAACGAATCCGGGTACGAAATGCAACTGTGCGATTCTGAAACGGAGGATGagctgcaaatgcagcaggCGAGGGGCTCGCCCAGCGCACGACCCGTCTACGTCTGCGAGCTGTGCAAAGTGCAGTGCAAGCGCAAATACGAGATGATCCAGCATCAGCGAGCGATGCATCGGTTCGACAAAATGCCCCACGAATGCGAGTTCTGCATattcaagtgtgtgtgcaagAGCATCATGGATCAGCACAAGCAATCGCAGTGTCAAAGCGCCGAGAAGAAGCTGGCGTGCAGTAAATGCAGCTACAAATTCATGTGGCCAGAGAATCTGCAGCATcacatgctgctgcagcatggcAGCATTGATTCACAGTCGACTCCTGCGGCCGCCATCAGTGATGCAGCCAGCGCAGATCAGCTGTCAGCTGTGGCGGCTAATCCCGCTATTGCGGCCGAGGATGTGCAGCTGCTACAGTGTCCGCACTGCGATCGCACGTACCAGATGAAGGCACGCCTCAACAATCACATTCGCGATGTGCACATCAATGGGGATCGGAAGCGTAAGGAGGCCATCAAAAAGTTCCTCTGCTCGCTCTGCGGTCGGGAAACCCAGTCGGCGGCGACACTGGTCACCCACATGCGTCGGCATACGGGCGAGAAGCCGTTCAAATGTGATCTATGTGAAATGGCCTTCCCGCGGCACTCGGAGATGATGTCTCACCGGCGAATGCACACGGGCGAGAAGCCCTTCCATTGCACGGTCTGTGGCAAGGATTTCGCCCGGTCCGACAAGCTGAAGCGGCACATGTTGACGCACAGCGGATTGAAGCCACACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCGAAGGATCTGAAACTccatctgcagcagcacacGGGCGAGTGTCCCTTCATATGTGGCACCTGTGGCGAGCGTTTCATACAGGGAACCGCCTTGGAGAAGCATCGCATGATGCGACGTCACTTTGACGAGGTGGAGGAGCGCCccaacgccaacaacagccacacaACAACCGCTTAG
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHIELDETLAQQLPQCLCGNCARKLIGAYYYVKQAHAANELLMNHVDRLESNKTTVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTVQNANDVDLELDNKKSNDPLNMLEPVKQEVEPTAGRTPNLQEPQEYKADIEQDEESLDDLPLQQRARKWKQTGTIRAVKRSIFKCTECPKIFKRPEYLKQHATRAHKSKTDWFSCSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDLNMCKPHGYKLIECMICQSQYDKIADLRRHLEQHPDIVGFGARSNMQPHELAELFYPDAKHISLEQLKALIRKDLDAGIYQRFYSITNQSGYEMDLDSSETESDADRDVDEQQLKRNIPKAKYTCELCNERCQRKYQLFDHQRLAHAWLDAPHVCGRCDARFVSLQLLRQHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRIINQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATAKPNGAKRITCKICNLHFERICDLRAHIQLELKLALSLHQNYDSLQNYSITNESGYEMQLCDSETEDELQMQQARGSPSARPVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECEFCIFKCVCKSIMDQHKQSQCQSAEKKLACSKCSYKFMWPENLQHHMLLQHGSIDSQSTPAAAISDAASADQLSAVAANPAIAAEDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERPNANNSHTTTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00476760;
80% Identity: -