Laer008057.1
Basic Information
- Insect
- Liodrosophila aerea
- Gene Symbol
- -
- Assembly
- GCA_035045005.1
- Location
- JAWNNL010000782.1:16764-19984[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.3e-06 9.2e-05 22.8 1.7 1 23 223 246 223 246 0.95 2 17 0.004 0.29 11.8 1.9 1 23 253 275 253 275 0.98 3 17 0.11 8.4 7.2 0.2 2 23 307 328 306 328 0.95 4 17 0.023 1.7 9.4 4.1 1 23 418 441 418 441 0.97 5 17 0.28 20 6.0 0.6 1 19 448 466 448 469 0.93 6 17 0.052 3.8 8.3 5.5 1 23 478 500 478 500 0.95 7 17 9.3e-06 0.00068 20.1 0.7 1 23 507 530 507 530 0.97 8 17 9.4e-05 0.0069 16.9 1.2 2 23 538 559 537 559 0.96 9 17 0.0037 0.27 11.9 0.3 2 21 586 605 585 606 0.94 10 17 0.0044 0.32 11.7 2.0 1 23 663 686 663 686 0.96 11 17 0.0074 0.54 10.9 0.8 1 23 723 746 723 746 0.94 12 17 0.00014 0.01 16.3 1.6 2 23 790 812 789 812 0.95 13 17 0.00089 0.066 13.8 0.3 1 23 826 848 826 848 0.95 14 17 0.00012 0.0085 16.6 1.2 1 23 854 876 854 876 0.99 15 17 3.7e-07 2.7e-05 24.5 2.6 1 23 882 904 882 904 0.98 16 17 1.2e-05 0.00088 19.7 3.8 1 23 910 932 910 932 0.97 17 17 0.0022 0.17 12.6 0.2 1 23 938 962 938 962 0.90
Sequence Information
- Coding Sequence
- ATGAAGTTGCCCGTAATGTGCCGCACTTGCGACGCAAGGGAAACGGAGAAATTGTATAAGCTTGCTACGGCCACCAAACGGTTTCCGGATAAATTGCTCTCTGATATTTTAGCGGAATTGACTCACATTGAGGTGGACGATTTATTGGCCCAGCAGCTGCCCCAATGTCTGTGCAGCACCTGTGCCCGTAAATTAATCAGCGCCTATTACTACGTGAAGCAGGCGATTGCGGCGAATGAGGTCCTCATCAACCATGTGCAGGACAGCGGAAAAGCCGTGGTCTCCGACTGCCTGCAAGAAGTGCCCATGGAGTTATGTGCCGAGCAGCATGTGGAGATAAAATTGGAAACCGAGGAAGACGATGTGGAAAATGATATAACCTGCACAGAACTGCCCGAGTTTACTACAGTACAAAACGCTATTGATGTCGATGTTGATGTCCAAGCGCAGAGTCCTTCATTCAATAAAAAGTCAACGGATCCGTTAACAATGTTTGACCCCGTCAAACAGGAGGAGGATGTGCCCCAAACAAGAGCATCGCTCATTAAGAAGAATGAGTGCTTGAAGACTGACAATGAGGATGATTCCCTCGATGATTTGCCGTTGAAACAGCGCGTTAAAAAGTGGAAACTTACGGACAAACTGCGGGCATTAAAGAGGCAAATTTTCAAGTGCAAAGACTGTCCCAAGAGTTTCAAACGTCCCGAGTATCTAAAGCAGCATTCATCGCGTGCCCACAGGCCGAAGACTGATTGGTACTCCTGCTCCTTTTGTATACGCCAATTTCGGCACGCGGAAGCGCTGCAAACACATCTCAAAGTCCATAGGGACTCGAAGCGGTCAGCCAACTTGGGCGAAAGTAAAAGGGCCAAGGACATCGATGTGAATGTATGCAAACCGCATGGCTACAAGCTAATCGAGTGCATGATCTGTCAAAGTCGATATGATAAGATATCGGATTTGCGAAATCATCTGGAACAGCACCCGGATATTATAAGCTTTGGAACACGTACGAATATGTCTATAAATGAGCTGGCTGAACTGTTCTATCCCGATGCCAAGGACATGAGCGAGGATGCATTGAAGCAGCTGATACGAAAAGATTTGGCTTCCGGAATATATCAGCGTTTCTATTCGATCACTGATCAATCGGGCTATGAAATGGATCTGGATAGTTCTGAGACGGAAAGCGAAGCCGAGCTCGATGGCGATGAGCAGTCCAAGGAGCTGCGAAACATACCCAAATCTAGGTACAGCTGTGAGCTCTGCCAGGTGCGTTGCCAGCGCAAGTATCAGCTCTACGAACACCAACGCCAGTCGCATGCCTGGCTGGATGCGCCTCACGTCTGTGGTCGGTGCGATGGCCGCTTTGTGAGCCTGCAACTGCTGCGGCATCATAACGAATCCCAATGCAAAAACTCTCAGAAACGCTTCCTGTGCCACAAGTGTCCGCTGCGCTTCCGCTGGCGGCATAATCTCAAACTGCACACACGCGAGCATAGAACCACCAATCAGACATTCGAGTGCGCCGACTGCAAGCGCGTCTTTGACAAAAAGAAATCCTTGACGGTGCATTTGCGCAGCGTTCATGTGGAGCAATCCAAGCTCATACCCTGCCAATGGTGCACACGCAAATTCTATCGGCGGGATTATCTGGTGAAGCATCTGAAGCGCCACGGGATTAGGGAACAGGATATACCGCTGGCCGAGACACTAATCGCAGCCACATCAAAGCCCAATGGAGCCAAGCGGATTACGTGTAAGATCTGTCACATGCACTTCGATCGCATCATCGATTTGCGGGCTCACATTCAGCTGGAACTGAAGCTCTCCTTGTCCCTGCACCAAAACTATGATTCGCCACACAACTATTCCATAACAAACGAATCGGGCTACGAACTGGAACTGGGCGACTCTGAGACGGAGGATGAAATGCCGCAGCAGATGCACATGCCATCGAGTGTCTCGCCCGGCTCACGCCTCGTCTATGTCTGTGAGCTGTGCAAGGTGCAGTGTAAGCGCAAGTACGAGATGATACAGCATCAGCGGGCCATGCATCGCTTCGACAAGATGCCACACGAGTGCGATCACTGCAtcttcaagtgtgtgtgcaagAGCATCATGGATCAGCACAGACAGTCGCAGTGTCACAGCTCGGAGAAGAAGTATGCCTGCAGTAGATGTGGCTACAAGTTCATGTGGCCCGACAATCTGCAGCAGCACATACACTTGCAACACGGCGCCAATGCCGATGCCGAAGTGGAAGCTAATGAATCATCAGCAGCGCCAGCTGCCACAACCAGCGCTGATCGCATTCCAGCAGCTGACACAACAGATGCTGCTCCAGCGGATGGTGTACAACTGCTGCAATGCCCACACTGTGATCGCACGTATCAGATGAAGTCACGGCTCAACAATCACATACGGGACGTGCATATCAATGGGGATCGCAAACGCAAGGAGGCCATCAAGAAGTTCCTGTGCTCGCTGTGTGGCCGGGAAACGCAATCGGCGGCCACATTGGTCACCCACATGCGCCGGCACACCGGCGAGAAGCCATTCAAGTGTGATCTCTGTGAAATGGCATTCCCAAGGCATTCGGAAATGATATCGCATCGTCGCATGCATACCGGAGAGAAGCCATTCCATTGTACGGTTTGCGGCAAGGATTTCGCACGTTCCGACAAACTGAAGCGTCACATGCTAACCCACAGTGGTTTGAAGCCGCACAAGTGCACCTATTGCGACAAGAGCTATCGTCAGGCCAAGGATCTGAAGCTACACTTGCAACAGCATACCGGAGAGTGCCCCTTCATCTGTGGCACCTGCGGCGAGCGCTTCATACAGGGCACAGCGCTCGAGAAGCATCGCATGATGCGACGCCACTTCGACGAGGTGGACGAACGCACCACAATACACACCGTAGCCACAGCCAATTAG
- Protein Sequence
- MKLPVMCRTCDARETEKLYKLATATKRFPDKLLSDILAELTHIEVDDLLAQQLPQCLCSTCARKLISAYYYVKQAIAANEVLINHVQDSGKAVVSDCLQEVPMELCAEQHVEIKLETEEDDVENDITCTELPEFTTVQNAIDVDVDVQAQSPSFNKKSTDPLTMFDPVKQEEDVPQTRASLIKKNECLKTDNEDDSLDDLPLKQRVKKWKLTDKLRALKRQIFKCKDCPKSFKRPEYLKQHSSRAHRPKTDWYSCSFCIRQFRHAEALQTHLKVHRDSKRSANLGESKRAKDIDVNVCKPHGYKLIECMICQSRYDKISDLRNHLEQHPDIISFGTRTNMSINELAELFYPDAKDMSEDALKQLIRKDLASGIYQRFYSITDQSGYEMDLDSSETESEAELDGDEQSKELRNIPKSRYSCELCQVRCQRKYQLYEHQRQSHAWLDAPHVCGRCDGRFVSLQLLRHHNESQCKNSQKRFLCHKCPLRFRWRHNLKLHTREHRTTNQTFECADCKRVFDKKKSLTVHLRSVHVEQSKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGAKRITCKICHMHFDRIIDLRAHIQLELKLSLSLHQNYDSPHNYSITNESGYELELGDSETEDEMPQQMHMPSSVSPGSRLVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECDHCIFKCVCKSIMDQHRQSQCHSSEKKYACSRCGYKFMWPDNLQQHIHLQHGANADAEVEANESSAAPAATTSADRIPAADTTDAAPADGVQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVDERTTIHTVATAN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00519319;
- 90% Identity
- -
- 80% Identity
- -