Basic Information

Insect: Drosophila mulleri
Gene Symbol: -
Assembly: GCA_035047565.1
Location: JAWNPK010000069.1:5730859-5734201[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.8e-06 0.00029 21.2 0.7 1 23 220 243 220 243 0.95

2 17 0.00073 0.056 14.0 2.9 1 23 250 272 250 272 0.98

3 17 0.36 27 5.6 0.1 2 23 304 325 303 325 0.94

4 17 0.0001 0.008 16.7 1.5 1 23 414 437 414 437 0.97

5 17 0.084 6.5 7.5 0.2 1 19 444 462 444 464 0.95

6 17 0.007 0.54 10.9 4.0 1 23 474 496 474 496 0.95

7 17 2.1e-06 0.00016 22.0 0.8 1 23 503 526 503 526 0.97

8 17 8.8e-05 0.0068 16.9 1.2 2 23 534 555 533 555 0.96

9 17 0.0056 0.43 11.2 0.8 2 21 582 601 581 602 0.94

10 17 0.0041 0.31 11.7 2.0 1 23 656 679 656 679 0.96

11 17 0.047 3.6 8.3 0.2 3 23 718 739 716 739 0.93

12 17 0.00035 0.027 15.0 1.0 2 23 779 801 778 801 0.95

13 17 0.00083 0.064 13.8 0.3 1 23 815 837 815 837 0.95

14 17 0.00013 0.01 16.4 1.6 1 23 843 865 843 865 0.99

15 17 3.4e-07 2.7e-05 24.5 2.6 1 23 871 893 871 893 0.98

16 17 1.1e-05 0.00087 19.7 3.8 1 23 899 921 899 921 0.97

17 17 0.0021 0.16 12.6 0.2 1 23 927 951 927 951 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.8e-06	0.00029	21.2	0.7	1	23	220	243	220	243	0.95
2	17	0.00073	0.056	14.0	2.9	1	23	250	272	250	272	0.98
3	17	0.36	27	5.6	0.1	2	23	304	325	303	325	0.94
4	17	0.0001	0.008	16.7	1.5	1	23	414	437	414	437	0.97
5	17	0.084	6.5	7.5	0.2	1	19	444	462	444	464	0.95
6	17	0.007	0.54	10.9	4.0	1	23	474	496	474	496	0.95
7	17	2.1e-06	0.00016	22.0	0.8	1	23	503	526	503	526	0.97
8	17	8.8e-05	0.0068	16.9	1.2	2	23	534	555	533	555	0.96
9	17	0.0056	0.43	11.2	0.8	2	21	582	601	581	602	0.94
10	17	0.0041	0.31	11.7	2.0	1	23	656	679	656	679	0.96
11	17	0.047	3.6	8.3	0.2	3	23	718	739	716	739	0.93
12	17	0.00035	0.027	15.0	1.0	2	23	779	801	778	801	0.95
13	17	0.00083	0.064	13.8	0.3	1	23	815	837	815	837	0.95
14	17	0.00013	0.01	16.4	1.6	1	23	843	865	843	865	0.99
15	17	3.4e-07	2.7e-05	24.5	2.6	1	23	871	893	871	893	0.98
16	17	1.1e-05	0.00087	19.7	3.8	1	23	899	921	899	921	0.97
17	17	0.0021	0.16	12.6	0.2	1	23	927	951	927	951	0.90

Sequence Information

Coding Sequence: ATGAAGCTACCCGTCATGTGTCGCACATGCGATGCAAGAGACACGGATAAACTATACAAGCTGGCTACATCCACCAAACGATTTCCAGATAAACAGCTCTCCGATATTTTAGCTGAACTAACGCACATTGAATTGGATGAAACTTTGGCACAACAGCTGCCGCAATGTCTGTGTGGTAATTGTGCGAGAAAGCTAATTGGCGCCTATTATTATGTGAAGCAGGCGCATGCAGCAAATGAGCTCCTGATGAATCATGTGGACCGCCTGGAGAGCAATAAAACTACAGTCAACGACTGCCTGCAGGAGGCGCCCATGGAATTGTGTGCCGAGCAACATGTGGAGATCAAAATGGAAacagaggaggaggaggctgAGAATGATATCACCTGCACGGAACTGCCGGAGTTCACAACAGTACAAAATGCCAACGATGTGGACGTGGAGCTGGATAATAAGAAGTCCAATGATCCGCTCAACATGCTCGAGCCAGTGAAACAGGAGATGGAGCCAGCCGCCGGTCGCACACCAAATTTACAAGAGCCGCAAGAATATAAGGCTGATATTGAAGATgaagaATCCCTTGATGATTTGCCTTTGCAACAGCGCGCACGCAAGTGGAAGCAAACCGGAACGATTCGCACTGTGAAGCGCTCCATTTTTAAGTGTACCGAATGCCCCAAGATTTTCAAACGACCGGAATATCTGAAGCAGCATGCAACACGGGCGCATAAGTCAAAGACCGATTGGTTTTCCTGCTCTTATTGCATACGCAAGTTCAGTCATCGAGAGGCTCTGCAGTCGCACCTGAAGGTGCATCGGGATTCAAAACGATCAGCGAATCTGGGCGAAAGTAAAAAGGCCAAGGATATAGATTTAAACATGTGCAAGCCACATGGCTATAAGCTAATCGAGTGTATGATTTGCCAGAGTCAATACGATAAGATAGCGGATCTACGACGACATCTGGAACAGCATCCGGATATCGTTGGATTCGGTGCACGCTCCAATATGCAGCCGCACGAGTTGGCCGAACTCTTCTATCCGGATGCCAAGCATATCAGCGTGGAGCAGCTAAAAGCGCTCATACGCAAAGATCTGGATGCCGGCATTTATCAACGTTTCTATTCCATTACCAATCAGTCGGGCTATGAAATGGACCTGGACAGCTCCGAGACAGAAAGCGATGCTGAACGGGATGTcgatgagcagcagctgaagcgcaACACACCCAAAGCCAAGTACACCTGTGAACTGTGCAACGAACGCTACCAGCGTAAATACCAGCTGTTTGATCATCAACGTCTGGCGCACGCCTGGCTGGATGCGCCGCATGTCTGCGGACGCTGTGATGCGCGCTTTGTtagcctgcagctgctgcgacaACACAACGAGCTGCAGTGCAAGAATGCTCAGAAACGCTTCCTCTGCCACAGATGTCCGCTGCGCTTCCGCTGGCGTCACAATCTAAAGGCGCATATACGTGAACACCGCATTATTAATCAAACCTATGAGTGCAACGATTGCAAGCGTGTGTTCGACAAGAAGAAATCCCTCACCGTACACATGCTCAGCGTGCATGCGGAGGAATCGAAACTCATACCGTGCCAATGGTGTACCCGCAAGTTCTATCGACGTGACTATTTGGTGAAGCATCTGAAGCGACATGGTATACGGGAGCAGGATATACCGCTCGCCGAAACGCTAATTGCAGCCACCGCGAAACCGAATGGCGCTAAGCGCATCACCTGTAAGATTTGTAACCTTCACTTTGAGCGCATCTGTGACCTGCGAGCGCACATCCAGCTGGAGCTTAAGCTGGCCTTGTCGCTGCACCAGAACTACGATTCGCTGCAAAACTACTCGATTACAAACGAATCCGGGTACGAAATGCAACTGAACGATTCTGAAACCGAGGATgagctgcaaatgcagcaggCGAGGGGCTCGCCCAGCGCACGACCCGTCTACGTTTGCGAGCTGTGCAAAGTGCAGTGCAAGCGCAAATACGAGATGATCCAGCATCAGCGAGCGATGCATCGGTTCGACAAAATGCCGCACGAATGCGAGTTCTGCATattcaagtgtgtgtgcaagAGCATCATGGATCAGCACAAGCAATCGCAGTGTCAAAGCGCCGAGAAGAAGCTGGCGTGCAGTAAATGCAGCTACAAATTCATGTGGCCAGAgaatctgcagcagcacatcTTGTTGCAGCATGGCAGCATTGATTCACAGTCGGCTCCTGCGGCCGCCATCAGCGATGCAGCCAGCGCAGATCAGCTGTCAGCTGTGGCCGCTAATCCCTCTGTTGCGGCCGAAgatgtgcagctgctgcagtgtcCGCACTGCGATCGCACGTACCAGATGAAGGCGCGCCTCAACAATCACATTCGCGATGTGCACATCAACGGGGATCGGAAGCGTAAGGAGGCCATCAAGAAGTTCCTCTGCTCGCTCTGCGGTCGGGAAACCCAGTCGGCGGCGACACTGGTCACCCACATGCGTCGGCATACGGGCGAGAAGCCGTTCAAATGTGATCTATGTGAAATGGCCTTCCCGCGGCACTCGGAGATGATGTCTCATCGGCGAATGCACACGGGCGAGAAGCCCTTCCATTGCACGGTCTGTGGCAAGGATTTCGCCCGGTCCGACAAGCTGAAGCGGCACATGCTGACGCACAGCGGATTGAAGCCACACAAGTGCACCTACTGCGACAAGAGCTATCGCCAGGCGAAGGATCTGAAACTccatctgcagcagcacacgGGCGAGTGCCCCTTCATATGTGGCACCTGTGGCGAGCGTTTCATACAGGGAACCGCCTTGGAGAAGCATCGCATGATGCGTCGTCACTTTGACGAGGTGGAGGAGCGCCCCAACGCCAACCACAGCCACACAGCAACCGCTTAG
Protein Sequence: MKLPVMCRTCDARDTDKLYKLATSTKRFPDKQLSDILAELTHIELDETLAQQLPQCLCGNCARKLIGAYYYVKQAHAANELLMNHVDRLESNKTTVNDCLQEAPMELCAEQHVEIKMETEEEEAENDITCTELPEFTTVQNANDVDVELDNKKSNDPLNMLEPVKQEMEPAAGRTPNLQEPQEYKADIEDEESLDDLPLQQRARKWKQTGTIRTVKRSIFKCTECPKIFKRPEYLKQHATRAHKSKTDWFSCSYCIRKFSHREALQSHLKVHRDSKRSANLGESKKAKDIDLNMCKPHGYKLIECMICQSQYDKIADLRRHLEQHPDIVGFGARSNMQPHELAELFYPDAKHISVEQLKALIRKDLDAGIYQRFYSITNQSGYEMDLDSSETESDAERDVDEQQLKRNTPKAKYTCELCNERYQRKYQLFDHQRLAHAWLDAPHVCGRCDARFVSLQLLRQHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRIINQTYECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATAKPNGAKRITCKICNLHFERICDLRAHIQLELKLALSLHQNYDSLQNYSITNESGYEMQLNDSETEDELQMQQARGSPSARPVYVCELCKVQCKRKYEMIQHQRAMHRFDKMPHECEFCIFKCVCKSIMDQHKQSQCQSAEKKLACSKCSYKFMWPENLQQHILLQHGSIDSQSAPAAAISDAASADQLSAVAANPSVAAEDVQLLQCPHCDRTYQMKARLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMMSHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPHKCTYCDKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQGTALEKHRMMRRHFDEVEERPNANHSHTATA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00476760;
80% Identity: -