Basic Information

Insect: Drosophila flavopinicola
Gene Symbol: -
Assembly: GCA_035042425.1
Location: JAWNLL010000442.1:2279159-2282699[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 7.6e-06 0.00047 20.5 0.8 1 23 222 245 222 245 0.95

2 17 0.0038 0.24 12.0 1.6 2 23 253 274 252 274 0.96

3 17 1.2 77 4.1 0.1 2 23 306 327 305 327 0.95

4 17 0.0034 0.21 12.1 4.6 1 23 417 440 417 440 0.97

5 17 0.086 5.3 7.7 0.5 1 19 447 465 447 467 0.94

6 17 0.008 0.5 10.9 4.0 1 23 477 499 477 499 0.95

7 17 3.3e-06 0.0002 21.6 0.9 1 23 506 529 506 529 0.97

8 17 0.0001 0.0063 16.9 1.2 2 23 537 558 536 558 0.96

9 17 0.0037 0.23 12.0 0.1 2 21 585 604 584 605 0.94

10 17 0.014 0.9 10.1 2.2 1 23 658 681 658 681 0.96

11 17 0.02 1.2 9.7 0.6 2 23 719 741 718 741 0.94

12 17 0.00015 0.0095 16.4 1.6 2 23 777 799 776 799 0.95

13 17 0.00095 0.059 13.9 0.3 1 23 813 835 813 835 0.95

14 17 0.00012 0.0077 16.6 1.2 1 23 841 863 841 863 0.99

15 17 3.9e-07 2.5e-05 24.5 2.6 1 23 869 891 869 891 0.98

16 17 1.8e-06 0.00011 22.4 2.2 1 23 897 919 897 919 0.98

17 17 0.0024 0.15 12.6 0.2 1 23 925 949 925 949 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	7.6e-06	0.00047	20.5	0.8	1	23	222	245	222	245	0.95
2	17	0.0038	0.24	12.0	1.6	2	23	253	274	252	274	0.96
3	17	1.2	77	4.1	0.1	2	23	306	327	305	327	0.95
4	17	0.0034	0.21	12.1	4.6	1	23	417	440	417	440	0.97
5	17	0.086	5.3	7.7	0.5	1	19	447	465	447	467	0.94
6	17	0.008	0.5	10.9	4.0	1	23	477	499	477	499	0.95
7	17	3.3e-06	0.0002	21.6	0.9	1	23	506	529	506	529	0.97
8	17	0.0001	0.0063	16.9	1.2	2	23	537	558	536	558	0.96
9	17	0.0037	0.23	12.0	0.1	2	21	585	604	584	605	0.94
10	17	0.014	0.9	10.1	2.2	1	23	658	681	658	681	0.96
11	17	0.02	1.2	9.7	0.6	2	23	719	741	718	741	0.94
12	17	0.00015	0.0095	16.4	1.6	2	23	777	799	776	799	0.95
13	17	0.00095	0.059	13.9	0.3	1	23	813	835	813	835	0.95
14	17	0.00012	0.0077	16.6	1.2	1	23	841	863	841	863	0.99
15	17	3.9e-07	2.5e-05	24.5	2.6	1	23	869	891	869	891	0.98
16	17	1.8e-06	0.00011	22.4	2.2	1	23	897	919	897	919	0.98
17	17	0.0024	0.15	12.6	0.2	1	23	925	949	925	949	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCAGTCATGTGCCGCACTTGCGATGCAAGGGACGCGGATAAACTGTATAAGTTGGCAACATCCACCAAAAGATTTCCAGATAAACAGCTTTCGGATATCTTAACCGAACTGACCCACATTGATGTGGATGGAACCTTGGCACATCAGCTGCCTCAATTTCTATGCGGCAATTGTGCGAGAAAACTAATTGCCGCCTATTATTATGTGAAGCAGGCGATGGCCGccaatgagctgctgctgaaccATGTGGGAAGCATGGAGGGCGACAAACCGGGGGTCAACGACTGCCTGCGGGAGGCACCCATGGAGCTATGCGCGGAACAGCATGTCGAGGTAAAACTGGAaacggaggaggaggaagcgGACAATGATATTACCTGCACGGAACTACCAGAGTTTACTACAGTACAAAATGCAATCGATGTGGAATTGGACATTGTTGATGAGCCGGATAACAAAAAGTCAGCAGATCCGCTCAATATGCTCGATTCAGTTAAACAGGAAGAGGATGCTCCGAGCAGAGCAGGAAATACTCAAGCAACACAATTGAAGGCTGATATTGACGAAGAAGActcCCTCGATGACTTGCCCTTGCAACAACGCGTTAGAAAGTGGAAACAAACTGATAAAGTGATTGCTGTCAAGCGAGCCATTTTCAAGTGCAAGGAATGCCCAAAGAGCTTCAAGCGGATCGAGTATCTGAAGCAGCATGCAGCACGGGCACACAAATCAAAAACCGATTGGTTGTCCTGCTCCTTCTGCATACGCAAATTCAGTCATCGGGAAGCGTTACAGGCACATCTCAAGGTGCATCGCGACTCGAAACGCTCAGCTAATTTGGGCGAGAGCAAAAAGGCCAAGGATATTGATGTGAATGTGTGCAAACCGCATGGCTATAAGCTCATCGAGTGCATGATCTGTCAGAGTCAGTACGACAAGATAGCGGATTTGCGACTacatctgcagcagcatccgGAAATTGTTAGCTTTGGCGCGCGGACAAATGTGGAGCCGCATGAGCTGGCTGAGCTCTTCTATCCCGATGCCAAGGATGTCAACGAGGATCAGCTGAAGGCGCTCATACGCAAAGACTTGTCGGCTGGCATTTATCAGCGCTTCTACTCGATAACCAATCAATCCGGCTACGAAATGGATCTGGACAGCTCCGAAACGGAAAGCGAAGCAGAACTGGATGCCGACGAACAGTCGCATCAACGACGCACCATACCCAAAGCCAAATACAGCTGCGAGCTGTGCAACGAGCGCTGCCAGCGCAAGTACCAGCTCTTTGATCATCAACGTCAGACGCACGCCTGGCTGGAGGCGCCTCACGTCTGCGGCCGATGCGATGCACGCTTCGTcagcctgcagctgctgcgacaTCACAACGAGCTGCAGTGCAAGAATGCCCAAAAGCGTTTCCTATGCCACAGGTGTCCGCTGCGCTTTCGCTGGCGGCACAATCTCAAGGCTCACATACGCGAGCATCGCATCACTAATCAAACCTTCGAGTGCAACGATTGCAAGCGCGTCTTTGACAAGAAGAAATCGCTGACGGTGCACATGCTCAGCGTGCATGCGGAGGAATCGAAGCTGATACCGTGCCAATGGTGTACCCGGAAGTTCTATCGGCGCGACTACTTGGTGAAGCATCTGAAGCGTCACGGCATACGGGAGCAGGACATACCGCTGGCCGAGACGCTCATTGCGGCCACATCGAAGCCGAATGGCCACAAGCGAATCACGTGCAAGATATGCAATCTGCAATTCGAACGCATCAACGATCTGCGCGCCCACATTCAGCTGGAACTGAAGTTGGCGCTGTCGCTGCACCAGAGCTACGATTCGCCGCACAACTACTCGATCACAAACGAGTCCGGCTACGAGTTGCAGCTGGCCGACTCCGAGACGGACGACGAGATGCACATGCCGGCTGCAGTCTCGCCGAGCTCACGCTCCGTCTACGTCTGCGAGCTGTGCAAGGTGCAGTGCAAGCGCAAGTTCGAGATGATTCAGCATCAGCGTGCCATGCATCGATTCGACAAGATGCCGTACGAGTGCGAGCTGTGCATATTCAAGTGCGTCTGCAAGAGCATCATGGAGCAGCACCGACAATCGCAGTGCCACAGCGCCGAGAAGAAACTGTCGTGCAGCAAGTGCAGCTACAAATTCATGTGGGCCGAGAATCTGCAACAGCACATGCAGCTGCAACATGGCGGCACCGAGGGCACACCGGCGCATCCCAGTGAAGCCAGCGCCGATCGTATACCGGCCATTCCCACCGATCCAGCAGCTGCGGCCGATggtgtgcagctgctgcagtgtcCGCACTGCGATCGCACGTATCAGATGAAGTCGCGCCTCAACAATCACATACGGGACGTGCACATCAATGGGGATCGCAAGCGGAAGGAGGCGATCAAGAAGTTCCTATGCTCGCTGTGCGGCCGGGAGACGCAATCCGCTGCCACATTGGTCACCCACATGCGTCGGCACACGGGCGAGAAGCCCTTCAAGTGCGATCTCTGCGAGATGGCCTTTCCGCGGCACTCCGAAATGATATCGCACAGACGGATGCACACGGGCGAGAAGCCCTTCCATTGCACCGTTTGTGGTAAGGATTTCGCACGCTCCGACAAGCTGAAGCGGCACATGCTCACGCACAGTGGTTTGAAACCGTACAAGTGCACATACTGCGACAAGAGCTATCGCCAGGCGAAGGATCTGAAgctgcatctgcagcagcacacCGGCGAGTGCACCTTCATCTGCGGCACCTGCGGCGAACGCTTCATTCAGGGCACAGCGCTGGAGAAGCATCGCATGATGCGACGTCACTTTGACGAGGTCGAGGAGCGTGCGACGAACACCTTAACTGCATAG
Protein Sequence: MKLPVMCRTCDARDADKLYKLATSTKRFPDKQLSDILTELTHIDVDGTLAHQLPQFLCGNCARKLIAAYYYVKQAMAANELLLNHVGSMEGDKPGVNDCLREAPMELCAEQHVEVKLETEEEEADNDITCTELPEFTTVQNAIDVELDIVDEPDNKKSADPLNMLDSVKQEEDAPSRAGNTQATQLKADIDEEDSLDDLPLQQRVRKWKQTDKVIAVKRAIFKCKECPKSFKRIEYLKQHAARAHKSKTDWLSCSFCIRKFSHREALQAHLKVHRDSKRSANLGESKKAKDIDVNVCKPHGYKLIECMICQSQYDKIADLRLHLQQHPEIVSFGARTNVEPHELAELFYPDAKDVNEDQLKALIRKDLSAGIYQRFYSITNQSGYEMDLDSSETESEAELDADEQSHQRRTIPKAKYSCELCNERCQRKYQLFDHQRQTHAWLEAPHVCGRCDARFVSLQLLRHHNELQCKNAQKRFLCHRCPLRFRWRHNLKAHIREHRITNQTFECNDCKRVFDKKKSLTVHMLSVHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGIREQDIPLAETLIAATSKPNGHKRITCKICNLQFERINDLRAHIQLELKLALSLHQSYDSPHNYSITNESGYELQLADSETDDEMHMPAAVSPSSRSVYVCELCKVQCKRKFEMIQHQRAMHRFDKMPYECELCIFKCVCKSIMEQHRQSQCHSAEKKLSCSKCSYKFMWAENLQQHMQLQHGGTEGTPAHPSEASADRIPAIPTDPAAAADGVQLLQCPHCDRTYQMKSRLNNHIRDVHINGDRKRKEAIKKFLCSLCGRETQSAATLVTHMRRHTGEKPFKCDLCEMAFPRHSEMISHRRMHTGEKPFHCTVCGKDFARSDKLKRHMLTHSGLKPYKCTYCDKSYRQAKDLKLHLQQHTGECTFICGTCGERFIQGTALEKHRMMRRHFDEVEERATNTLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519319;
90% Identity: iTF_00538370;
80% Identity: -